گل بنگلزئی نا افسانہ غاتا کتاب، دڑد آتا گواچی؛ نا جاچ اس

When the industrial revolution and progressive tendencies in the nineteenth century influenced every sphere of life, literature could also not escape such trends. At that time, fiction (short story) was introduced as a new genre in literary world and soon it managed to generate a distinction. Like the other languages ​​of the world, fiction writers of Brahui literature also effectively adopted this genre. Among the pioneer Brahui fiction writers, the name of Gul Bangulzai is also well known who initiated the fiction writing. The effects of the progressive literary movement can be seen in his fiction writings. Gul Bangulzai in his book of fiction, Darhd ata Guachi, centralized the topic on the problems of ordinary individuals and lower class of the region. The book was first published in 1984, thus, standing the second book in Brahui literature after Dr. Taj Raisani's book, Anjeer na Phul. In, Darhd ata Guachi, Gul Bangulzai mainly reflected the problems of village life in a unique manner. Gul Bangulzai skillfully identified the problems of farmers, laborers, women, shepherds, and gypsies. Additionally, the themes also include poverty, starvation, the hardships of weather, cruelties of higher class, the culture and traditions of people of Baluchistan, and their mentality. The fiction also depicted the stunning natural landscapes of this region. In the fictions of Gul Bangulzai frustration, deprivation, helplessness, cruelties, and poverty are observable. However, ultimately, the message it conveys that after the dark night there is a dawn of new morning and hope which is another distinguished beauty of the fictions of Gul Bangulzai, bestows him a unique status in Brahui literature wherein most fictions revolves around the complications of village life.

Poststroke dendritic arbor regrowth requires the actin nucleator Cobl

Ischemic stroke is a major cause of death and long-term disability. We demonstrate that middle cerebral artery occlusion (MCAO) in mice leads to a strong decline in dendritic arborization of penumbral neurons. These defects were subsequently repaired by an ipsilateral recovery process requiring the actin nucleator Cobl. Ischemic stroke and excitotoxicity, caused by calpain-mediated proteolysis, significantly reduced Cobl levels. In an apparently unique manner among excitotoxicity-affected proteins, this Cobl decline was rapidly restored by increased mRNA expression and Cobl then played a pivotal role in poststroke dendritic arbor repair in peri-infarct areas. In Cobl knockout (KO) mice, the dendritic repair window determined to span day 2 to 4 poststroke in wild type (WT) strikingly passed without any dendritic regrowth. Instead, Cobl KO penumbral neurons of the primary motor cortex continued to show the dendritic impairments caused by stroke. Our results thereby highlight a powerful poststroke recovery process and identified causal molecular mechanisms critical during poststroke repair.

Mental Imagery in Bertrand Russell’s Nobel Lecture “What Desires Are Politically Important?”

The article presents the analysis of the mental images of human desires and their verbalization techniques involved in Bertrand Russell’s Nobel lecture delivered in 1950. Human desires are non-material mental constructs that are not clearly defined in the dictionaries, their verbalization being complicated by the issues related to rationality, psychology of thinking, objectivity, and the variability of individual behavioral reactions. The results of the research suggest that the verbalization of desires is essentially complicated by social and cultural stereotypes. It has been noted that storytelling can be applied as one of the most effective techniques to create the required mental imagery of desires in the recipient’s mind. B. Russell’s unique manner of defining such politically important desires as acquisitiveness, vanity, glory, love of power, excitement is carefully analyzed. The use of figurative language as well as conceptual and stylistic metaphors that facilitate the process of shaping mental images of desires have also been the focus of our attention. Special consideration has been given to the analysis of the verbalization means of the politically important desires.

Konceptualne metafore sa sastavnicama ŽIVOT i SMRT u Kamenom spavaču Maka Dizdara

Conceptual metaphor is a cognitive mechanism often and gladly used in all discourse types, but it shows its maximum potentials in literature as it demystifies in an efficient and unique manner the experience, perception and mental schemas of a particular speaker – as both a member of a group and an individual. This paper analyzes the application of conceptual metaphorization in Mehmedalija Mak Dizdar’s Stone Sleeper with the concepts of LIFE and DEATH in the position of target domains with the aim of questioning its purpose, motivation and originality. The conceptual metaphors used in the collection are a clear reflection of the notion of human existence in the Bogumil spiritual tradition (the extremely negative intonation of the worldly and the rather positive intonation of the otherworldly reality) but, as it also turned out, in universal human thought. With each new insight into the motivic-thematic world of Dizdar’s poetics, its formal exceptionality and inexhaustibility of content are reaffirmed. This time, it was achieved using the apparatus of cognitive linguistics, i. e. by finding innovative metaphorical linguistic units expressing conventional conceptual metaphorization in Stone Sleeper.

Pregnancy Complications Can Foreshadow Future Disease—Long-Term Outcomes of a Complicated Pregnancy

During gestation, the maternal body should increase its activity to fulfil the demands of the developing fetus as pregnancy progresses. Each maternal organ adapts in a unique manner and at a different time during pregnancy. In an organ or system that was already vulnerable before pregnancy, the burden of pregnancy can trigger overt clinical manifestations. After delivery, symptoms usually reside; however, in time, because of the age-related metabolic and pro-atherogenic changes, they reappear. Therefore, it is believed that pregnancy acts as a medical stress test for mothers. Pregnancy complications such as gestational hypertension, preeclampsia and gestational diabetes mellitus foreshadow cardiovascular disease and/or diabetes later in life. Affected women are encouraged to modify their lifestyle after birth by adjusting their diet and exercise habits. Blood pressure and plasmatic glucose level checking are recommended so that early therapeutic intervention can reduce long-term morbidity. Currently, the knowledge of the long-term consequences in women who have had pregnancy-related syndromes is still incomplete. A past obstetric history may, however, be useful in determining the risk of diseases later in life and allow timely intervention.

Petr Rychkov’s Map of Iske (Inner or Old) Kazan of 4 July 1770

Research objectives: On the basis of a recently discovered map – found in the manuscript library of the Russian Academy of Sciences in St. Petersburg – of Iske Kazan’s fortification made by P.N. Rychkov in 1770, this article investigates the manner in which its population protected itself against its foes in the restless era that witnessed the dissolution of the Golden Horde and the transition to the Kazan khanate. It additionally asks why in fact this map was composed. Research materials: Combining the evidence of Rychkov’s map with archaeological findings and in dialogue with the relevant historiography, the authors place the map in its historical context and ponder its significance, and suggest why this map was made in 1770. Results and novelty of the research: It appears that Iske Kazan’s inhabitants turned to a unique manner to defend themselves against their enemies, using a wall-moat-wall design to prevent any storming by mounted troops, different from what has been hitherto thought about the ruins of this defensive structure. This manner of defending seems eminently well suited to the restless conditions prevailing in the Volga-Kama region around 1400 and the art of war as practiced in this region. The article additionally suggests why this map was made in 1770, linking it to the general desire of the Romanov government to discover much more precisely how its subjects lived their lives. This impetus was born from the introduction of the Western-European scientific mindset in Peter I’s reign, which paid much closer heed to a realistic understanding of nature and culture. The Russian Academy of Sciences mounted from the 1720s onward a host of scientific expeditions, which almost resemble voyages of discovery, to map the tsarist empire, of which Rychkov’s travels formed a part. The article hints at the possibility that such fact-finding missions gradually allowed the central government in St. Petersburg to increase its power over its subject peoples.

Animal Studies and the Early Modern Period

The burgeoning field of animal studies has facilitated the exploration of human-animal relations across a variety of disciplines. Following the animal turn in humanities scholarship, a number of studies published in the late 20th and early 21st centuries have demonstrated that animals reflected the social, cultural, and political concerns of the early modern period in a unique manner due to a shift in the ways in which animals were viewed and valued. This shift was largely caused by the increasing commodification of animals, the discovery of new creatures through global exploration, a renewed interest in investigating and documenting all earthly beings, and an enhanced concern for animal welfare. A range of early modern texts reflect this shift in the perception of animals through engaged interaction with conceptions of the human-animal divide and interrogation of human exceptionalism. Animals also inhabit a multitude of early modern texts in a less prominent manner because, as is the case in the modern world, animals lived alongside humans and were a fundamental part of everyday life. While these texts may not at first seem to reveal much detail about the lives of animals and how they were viewed in the early modern period, the field of animal studies has provided a method of bringing nonhuman beings to the fore. When analyzing the representation of nonhuman beings in early modern texts through the lens of animal studies a thorough consideration of the context in which such texts were written and investigation of the lived experience of the animals they seek to portray is required in order to capture, what leading animal studies scholar Erica Fudge terms, a holistic history of animals.

Effects of Abiotic Stress on Soil Microbiome

Rhizospheric organisms have a unique manner of existence since many factors can influence the shape of the microbiome. As we all know, harnessing the interaction between soil microbes and plants is critical for sustainable agriculture and ecosystems. We can achieve sustainable agricultural practice by incorporating plant-microbiome interaction as a positive technology. The contribution of this interaction has piqued the interest of experts, who plan to do more research using beneficial microorganism in order to accomplish this vision. Plants engage in a wide range of interrelationship with soil microorganism, spanning the entire spectrum of ecological potential which can be mutualistic, commensal, neutral, exploitative, or competitive. Mutualistic microorganism found in plant-associated microbial communities assist their host in a number of ways. Many studies have demonstrated that the soil microbiome may provide significant advantages to the host plant. However, various soil conditions (pH, temperature, oxygen, physics-chemistry and moisture), soil environments (drought, submergence, metal toxicity and salinity), plant types/genotype, and agricultural practices may result in distinct microbial composition and characteristics, as well as its mechanism to promote plant development and defence against all these stressors. In this paper, we provide an in-depth overview of how the above factors are able to affect the soil microbial structure and communities and change above and below ground interactions. Future prospects will also be discussed.

The necessity defence and anthropogenic global warming protests: The times they are a-changin’

The Extinction Rebellion protests of 2019 and 2020 resulted in peaceful protesters being charged for a range of minor, non-violent criminal offences. The defence to those charges is necessity, a defence tightly restricted in its use by the courts. This article argues that in the specific context of minor criminal offences committed during anthropogenic global warming (AGW) protests, necessity must be reconceptualised. This is particularly so given the growing international recognition of that defence in AGW protest matters, the increasing state prohibition on protest and the unique manner in which AGW protests subvert the strict application of the rule of law.

Moduli spaces of low-dimensional Lie superalgebras

In this paper, we study moduli spaces of low-dimensional complex Lie superalgebras. We discover a similar pattern for the structure of these moduli spaces as we observed for ordinary Lie algebras, namely, that there is a stratification of the moduli space by projective orbifolds. The moduli spaces consist of some families as well as some singleton elements. The different strata are linked by jump deformations, which gives a unique manner of decomposing the moduli space which is consistent with deformation theory.