Tryptophan-Free Diets: A Physiological Tool to Study Brain Serotonin Function

Physiology ◽  
2000 ◽  
Vol 15 (5) ◽  
pp. 260-264 ◽  
Author(s):  
F. Fadda
Keyword(s):  
Sexual Behavior ◽  
Brain Serotonin ◽  
Laboratory Animals ◽  
Serotonin Synthesis

Tryptophan-free diets produce a specific reduction of brain serotonin synthesis and release. This method for lowering neural serotonin function has been extensively used in both laboratory animals and humans to study the role of serotonin in a variety of behaviors, such as aggressiveness, sleep, sexual behavior, anxiety, mood, memory, and so forth.

scholarly journals Role of a Functional SNP of the Gene Coding Brain Serotonin Synthesis Rate-Limiting Enzyme Tph2 in Dilated Cardiomyopathy

2020 ◽  
Vol 118 (3) ◽  
pp. 426a
Author(s):  
Sachio Morimoto ◽  
Kengo Hayamizu ◽  
Miki Nonaka ◽  
Lei Li ◽  
Yuanyuan Wang
Keyword(s):  
Dilated Cardiomyopathy ◽  
Brain Serotonin ◽  
Synthesis Rate ◽  
Serotonin Synthesis ◽  
Gene Coding ◽  
Rate Limiting ◽  
Functional Snp

scholarly journals Oxytocin, Erectile Function and Sexual Behavior: Last Discoveries and Possible Advances

2021 ◽  
Vol 22 (19) ◽  
pp. 10376
Author(s):  
Maria Rosaria Melis ◽  
Antonio Argiolas
Keyword(s):  
Sexual Behavior ◽  
Sexual Behaviors ◽  
Erectile Function ◽  
Complex Function ◽  
Laboratory Animals ◽  
Men And Women ◽  
Male And Female ◽  
Female Sexual Behavior ◽  
Sexual Behavior In Animals

A continuously increasing amount of research shows that oxytocin is involved in numerous central functions. Among the functions in which oxytocin is thought to be involved are those that play a role in social and sexual behaviors, and the involvement of central oxytocin in erectile function and sexual behavior was indeed one of the first to be discovered in laboratory animals in the 1980s. The first part of this review summarizes the results of studies done in laboratory animals that support a facilitatory role of oxytocin in male and female sexual behavior and reveal mechanisms through which this ancient neuropeptide participates in concert with other neurotransmitters and neuropeptides in this complex function, which is fundamental for the species reproduction. The second part summarizes the results of studies done mainly with intranasal oxytocin in men and women with the aim to translate the results found in laboratory animals to humans. Unexpectedly, the results of these studies do not appear to confirm the facilitatory role of oxytocin found in male and female sexual behavior in animals, both in men and women. Possible explanations for the failure of oxytocin to improve sexual behavior in men and women and strategies to attempt to overcome this impasse are considered.

scholarly journals L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications

2009 ◽  
Vol 2 ◽  
pp. IJTR.S2129 ◽  
Author(s):  
Dawn M Richard ◽  
Michael A Dawes ◽  
Charles W Mathias ◽  
Ashley Acheson ◽  
Nathalie Hill-Kapturczak ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Therapeutic Agents ◽  
Brain Serotonin ◽  
Tryptophan Depletion ◽  
Serotonin Synthesis ◽  
Human Diet ◽  
Metabolic Functions ◽  
The Brain ◽  
Behavior And Cognition

An essential component of the human diet, L-tryptophan is critical in a number of metabolic functions and has been widely used in numerous research and clinical trials. This review provides a brief overview of the role of L-tryptophan in protein synthesis and a number of other metabolic functions. With emphasis on L-tryptophan's role in synthesis of brain serotonin, details are provided on the research uses of L-tryptophan, particularly L-tryptophan depletion, and on clinical trials that have been conducted using L-tryptophan supplementation. The ability to change the rates of serotonin synthesis in the brain by manipulating concentrations of serum tryptophan is the foundation of much research. As the sole precursor of serotonin, experimental research has shown that L-tryptophan's role in brain serotonin synthesis is an important factor involved in mood, behavior, and cognition. Furthermore, clinical trials have provided some initial evidence of L-tryptophan's efficacy for treatment of psychiatric disorders, particularly when used in combination with other therapeutic agents.

1625: Role of Estrogen Receptor β in the Regulation of Sexual Behavior in Male Mice

2004 ◽  
Vol 171 (4S) ◽  
pp. 429-429
Author(s):  
Masayoshi Nomura ◽  
Naohiro Fujimoto ◽  
Donald W. Pfaff ◽  
Sonoko Ogawa ◽  
Tetsuro Matsumoto
Keyword(s):  
Estrogen Receptor ◽  
Sexual Behavior ◽  
Estrogen Receptor Β ◽  
Male Mice

Calculations used for assessment of rapid maxillary expansion

ORL ro ◽  
2016 ◽  
Vol 1 (1) ◽  
pp. 24-26
Author(s):  
Ruxandra Bartok ◽  
Bogdan Dimitriu Dimitriu ◽  
Constantin Vârlan ◽  
Radu Stanciu ◽  
Georgiana Moldoveanu ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Elasticity Modulus ◽  
Rapid Maxillary Expansion ◽  
Laboratory Animals ◽  
Maxillary Expansion ◽  
Literature Reference ◽  
Bone Changes ◽  
Upper Jaw ◽  
Materials Used

Rapid maxillary expansion is defined as the release of medio-palatine suture using an orthopedic forces. The role of this procedure is to expand  the upper jaw in order to achieve the  broadening of the upper arch. This study was initiated to quantify the effects of disjunction and post- treatment bone changes, after an adequate contention which lasted for three weeks. This study  is  carried on laboratory animals (common breed rabbit) to determine tensile strength and the elasticity modulus of  biological materials  used in orthdodontics. The results of the study are consistent with those reported in the literature reference.  

scholarly journals The Dual Role of Media Internalization in Adolescent Sexual Behavior

2016 ◽  
Vol 46 (6) ◽  
pp. 1685-1697 ◽  
Author(s):  
Ann Rousseau ◽  
Ine Beyens ◽  
Steven Eggermont ◽  
Laura Vandenbosch
Keyword(s):  
Sexual Behavior ◽  
Dual Role ◽  
Adolescent Sexual Behavior ◽  
Media Internalization
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