scholarly journals Suppurative Mediastinitis Secondary toBurkholderia Cepaciain a Patient with Cystic Fibrosis

2006 ◽  
Vol 13 (4) ◽  
pp. 215-218 ◽  
Author(s):  
Ronald B George ◽  
Yannick Cartier ◽  
Alan G Casson ◽  
Paul Hernandez
Keyword(s):  
Cystic Fibrosis ◽  
Weight Loss ◽  
Case Report ◽  
Lung Function ◽  
Blood Cell ◽  
Burkholderia Cepacia ◽  
Clinical Course ◽  
Opportunistic Pathogen ◽  
Blood Cell Count ◽  
Present Case Report

Burkholderia cepaciais an important opportunistic pathogen among patients with cystic fibrosis (CF); it is associated with deterioration of lung function, poor outcome following lung transplantation and increased mortality. Fever, an elevated white blood cell count, weight loss and an often fatal deterioration in pulmonary function characterize a particular clinical course, termed ‘Cepacia syndrome’. The present case report describes a 40-year-old man with CF who developed Cepacia syndrome complicated by suppurative mediastinitis, from whichB cepaciawas isolated. Despite optimal medical and surgical therapy, this patient succumbed to his illness. Those caring for patients with CF should be aware of this potentially catastrophic complication ofB cepaciainfection, especially in the setting of Cepacia syndrome.

Burkholderia cepacia. [Descriptions of Fungi and Bacteria].

1994 ◽  
Author(s):  
G. S. Saddler
Keyword(s):  
Cystic Fibrosis ◽  
Lycopersicon Esculentum ◽  
Geographical Distribution ◽  
Allium Cepa ◽  
Leaf Spot ◽  
Burkholderia Cepacia ◽  
Allium Sativum ◽  
Opportunistic Pathogen ◽  
Agaricus Bitorquis ◽  
Cultivated Mushroom

Abstract A description is provided for Burkholderia cepacia. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Common host is Allium cepa, but can also cause disease in Allium sativum. Also identified as causing disease in Lycopersicon esculentum (63, 3168), a cavity disease of a cultivated mushroom (Agaricus bitorquis) (72, 5605) and a leaf spot on the a number of orchids including Cymbidium spp., Dendrobium sp. and Paphiopedilum spp. (66, 4326). The bacterium can also be found in soil, in clinical material, in disinfectant solutions and as an opportunistic pathogen of man and animals. It is gaining in significance as a major pathogen for sufferers of cystic fibrosis (Isles et al., 1984; McKevitt & Woods, 1984; Thomassen et al., 1985). DISEASE: Onion slippery skin; this is a rot of bulb scales, usually occurring at or near maturity, sometimes in storage. The bacterium does not appear to be strongly invasive, attacking plants that are damaged or weakened. Bacteria are thought to gain entry through the neck or leaf blades as the foliage falls over and the epidermis breaks, at maturity (64, 5550). GEOGRAPHICAL DISTRIBUTION: Worldwide. TRANSMISSION: Appears to be a soilborne wound pathogen.

High Ascitic Protein and White Blood Cell Count in Uncomplicated Alcoholic Liver Disease: Case Report

1979 ◽  
Vol 144 (8) ◽  
pp. 544-544
Author(s):  
Denis J. Frank ◽  
Marcos S. Souza Lima ◽  
Robert A. Herman ◽  
Eugene R. Schiff
Keyword(s):  
Case Report ◽  
Liver Disease ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Alcoholic Liver Disease ◽  
Blood Cell Count ◽  
Disease Case

scholarly journals Burkholderia cepacia complex: clinical course in cystic fibrosis patients

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Tania Wrobel Folescu ◽  
Claudia Henrique da Costa ◽  
Renata Wrobel Folescu Cohen ◽  
Orlando Carlos da Conceição Neto ◽  
Rodolpho Mattos Albano ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Burkholderia Cepacia ◽  
Clinical Course ◽  
Burkholderia Cepacia Complex

scholarly journals Clinical Case of Pregnancy and Follow-Up of Bartter Syndrome (Type II) with a Novel Mutation

2020 ◽  
pp. 1-5
Author(s):  
Laura Lūse ◽  
Anna Miskova ◽  
Dace Rezeberga ◽  
Gita Jansone ◽  
Kristīne Rasnača ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Clinical Course ◽  
Novel Mutation ◽  
Bartter Syndrome ◽  
Psychomotor Development ◽  
Syndrome Type ◽  
Type Ii ◽  
Present Case Report ◽  
Normal Ranges

Background: Bartter syndrome is a rare autosomal recessive inherited salt wasting tubulopathy, it`s incidence proportion is 1.2 cases per 1.000.000 live births. The present case - report discusses a clinical case of an antenatal Bartter syndrome (type II) with a novel mutation and it`s course from antenatal presentation to 6 months postpartum. Case Presentation: The case-report discusses a clinical case of an antenatal Bartter syndrome (type II) with a novel homozygous missense variant mutation in KCNJ1 gene: c.554C>T (p. Pro185Leu). Symptoms presented from 24 weeks of pregnancy as premature labour threats, maternal dyspnoea and severe polyhydramnios (amniotic fluid index 36 cm). Therapeutic interventions included use of indomethacin, dexamethasone, micronized progesterone and three consequent amnioreductions. Pregnancy was prolonged until 32 weeks and induced due to severe reoccurring polyhydramnios, progressing maternal dyspnoea and inability to perform next amnioreduction. Labour was complicated by severe placental abruption and new born – boy was referred to neonatal intensive care unit. Neonatal period was complicated by electrolyte abnormalities: hyponatremia, hypochloremic metabolic alkalosis, transient hyperkalaemia that gradually developed into hypokalaemia, hypercalcemia and elevated rennin and aldosterone levels characteristic to type II Bartter syndrome. At 6 months (corrected age 4 months) he is gaining weight within normal ranges and his psychomotor development is ahead of his corrected age, without any need for daily medications. Conclusion: The present case report describes the clinical course of a Bartter syndrome is of high importance, due to the reason that it shows clinical course of patient with novel mutation and offers one of the ways how to manage the disease. The described novel mutation may have favourable prognosis for neonate. The pregnancy should be managed as high-risk pregnancy with expertise in perinatal diagnostics and interventions. Early recognition, and interventions, are and essential to prolong a pregnancy and lessen prematurity complications.

scholarly journals Congenital brucellosis: A case report

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097557
Author(s):  
Yahya Ali Mohzari ◽  
Renad Abdullah Alshuraim ◽  
Syed Mohammed Basheeruddin Asdaq ◽  
Saud O. ALanazi ◽  
Najwa Alghamdi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Case Report ◽  
Pregnant Woman ◽  
Blood Cell ◽  
Brucella Abortus ◽  
Blood Cultures ◽  
Blood Cell Count ◽  
Premature Rupture ◽  
Kingdom Of Saudi Arabia ◽  
Gram Negative

Although rare, brucellosis is endemic in the Kingdom of Saudi Arabia (KSA). In the case presented here, a neonate was born at 29 weeks gestation with severe respiratory depression, pyrexia; hypotension and an elevated white blood cell count. Her mother was a 19-year-old pregnant woman who developed premature rupture of the membranes and went into labour early. Sepsis was suspected and so the neonate received dobutamine and empiric ampicillin/gentamicin. The mother reported visiting a farm during her pregnancy and so congenital brucellosis was considered a possibility. Blood cultures were positive for Gram-negative coccobacilli and serology confirmed the presence of Brucella abortus and B. meltiness. Antibiotic treatment was changed to rifampin/gentamicin/ciprofloxacin but on day 17 the baby deteriorated and gentamicin was discontinued and meropenem was added. The neonate gradually improved; meropenem was discontinued on day 24 and the baby was discharged from hospital on day 38.

scholarly journals Complete Genome Sequence of Burkholderia cenocepacia K56-2, an Opportunistic Pathogen

2020 ◽  
Vol 9 (43) ◽  
Author(s):  
Inmaculada García-Romero ◽  
Miguel A. Valvano
Keyword(s):  
Cystic Fibrosis ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Burkholderia Cepacia ◽  
Opportunistic Pathogen ◽  
Burkholderia Cenocepacia ◽  
Content Type ◽  
Advance Research

ABSTRACT Burkholderia cenocepacia K56-2, an opportunistic bacterium for people with cystic fibrosis (CF), belongs to the Burkholderia cepacia complex (Bcc) and is consistently used as a model pathogen. We describe here the closed genome sequence for this strain, which will help advance research in B. cenocepacia biology and omics studies.

scholarly journals Leptospirosis meningitis transmission from a pet mouse: a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Anne Christine Nordholm ◽  
Lars Haukali Omland ◽  
Steen Villumsen ◽  
Imad Al-Subeihe ◽  
Terese L. Katzenstein
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Healthy Woman ◽  
Blood Cell Count ◽  
Wide Range ◽  
Pet Rodents

Abstract Background Leptospirosis is a reemerging zoonosis with a worldwide distribution and a wide range of clinical manifestations. We report a case of leptospirosis meningitis in a previously healthy woman infected by her pet mouse. Case presentation A 27-year-old Caucasian woman with pet mice presented to our institute with a 1 week history of fever, headache, myalgia, vomiting, diarrhea, and dark urine. Her admission examination revealed neck stiffness, conjunctivitis, and icteric sclera. Her liver enzymes, bilirubin, white blood cell count, and C-reactive protein were elevated. Her cerebrospinal fluid showed an elevated white blood cell count. Polymerase chain reactions using her cerebrospinal fluid, blood, and urine showed negative results for leptospirosis, but the result of her microagglutination test was positive for Leptospira interrogans serovar sejroe with a more than threefold increase in paired sera. The patient was treated with ceftriaxone for 1 week, and her condition steadily improved. Conclusions This case report raises awareness of pet rodents as sources of leptospirosis. Leptospirosis meningitis should be considered in patients with meningeal symptoms and pet rodents.

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