scholarly journals Evaluation of Three New Strategies to Fight Obesity in Families

2010 ◽  
Vol 2010 ◽  
pp. 1-10 ◽  
Author(s):  
C. Luley ◽  
A. Blaik ◽  
S. Aronica ◽  
J. Dierkes ◽  
S. Kropf ◽  
...  
Keyword(s):  
Weight Loss ◽  
Calorie Restriction ◽  
Financial Incentive ◽  
Obese Children ◽  
Restriction Diet ◽  
Diet Versus ◽  
Design And Methods ◽  
Weight Loss Strategy ◽  
New Strategies ◽  
Low Glycemic Index

Aims. To evaluate 3 strategies to reduce weight in obese families.Research design and methods. 142 obese parents and 119 obese children kept a fat-calorie restriction diet. On top of this diet, the families were randomized in a three-factorial design to one or more of three weight-loss strategies: (1) an additional diet preferring carbohydrates having a low glycemic index (dual diet), (2) financial incentive, and (3) telemonitoring of weight and physical activity.Results. All children improved their BMI-SDS by0.18±0.25(P<.001) independently of the weight-loss strategy. In parents, relative losses of weight (kg) were−6.4% versus−4.0% for dual diet versus calorie restriction (P=.029),−6.9% versus−3.4% for with or without financial incentive (P=.002), and−8.0% versus−4.8% for with or without telemonitoring (P=.033). The weight loss after financial incentive plus dual diet plus telemonitoring was−14.4%.Conclusions. All strategies were effective in adults, in particular when combined. Children improved their BMI-SDS regardless of the strategy.

Physiological and Therapeutic Outcomes of Intermittent Fasting versus Calorie-Restriction Diet in Patients suffering from Metabolic Syndrome

2019 ◽  
Vol 3 (1) ◽  
pp. 4-19
Author(s):  
Doreen Susanne Micallef
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Weight Loss ◽  
Blood Glucose ◽  
Calorie Restriction ◽  
Fasting Blood Glucose ◽  
Hdl Cholesterol ◽  
Intermittent Fasting ◽  
Retrospective Case ◽  
Restriction Diet

The main objective of this study was to determine whether an intermittent fasting diet in combination with a CR diet results in better outcomes on risk factors associated with metabolic syndrome (such as lowering of triglycerides, fasting blood glucose, and blood pressure decrease in abdominal obesity and an increase in HDL-cholesterol and related weight loss for both male and female patients) than with a conventional CR diet alone. A 12-week retrospective case-control study was carried out and involved 78 females and 22 males who exhibited or were receiving medications for three or more conditions related to metabolic syndrome and who completed the study out of 120 participants at baseline. These were randomly assigned to either a conventional calorie-restriction diet or to an intermittent-fasting diet. Relevant baseline parameters were measured during the first encounter and were then repeated after twelve weeks. Professional contact was maintained on a fortnightly basis for both groups. Subjects randomly assigned to the intermittent fasting diet lost more weight than subjects on a conventional calorie-restriction diet after 12 weeks (mean ± SD, 5.7 ± 3.2 kg vs 11.4 ± 6.4 kg; p < 0.001). There were also statistically significant decreases in waist circumference (10.1 ± 7.2 cm vs 4.5 ± 3.3 cm; p < 0.001), serum triglycerides (0.31 ± 0.29 mmol/l vs 0.16 ± 0.16 mmol/l; p = 0.002), and systolic blood pressure (11.1 ± 8.2 mm Hg vs 5.2 ± 4.8 mm Hg; p < 0.001) and an increase in HDL-cholesterol (0.25 ± 0.16 vs 0.14 ± 0.15 mmol/l; p = 0.001). However, no statistically significant changes in diastolic blood pressure and fasting blood glucose were recorded. The intermittent fasting diet gave better weight loss outcomes (6.67% vs 12.35%) than did the conventional calorie restriction diet when compared to the baseline weight after the conclusion of the 12-week programme. The intermittent fasting diet was also associated with statistically significant improvements in four out of the six parameters measured and associated with metabolic syndrome. Longer-term studies are required to determine whether these outcomes will be maintained over longer periods of time assuming that there is compliance by the participants.

scholarly journals Central Role of Cognitive Control Networks in Weight Loss During Voluntary Calorie Restriction

2017 ◽  
Author(s):  
Selin Neseliler ◽  
Wen Hu ◽  
Kevin Larcher ◽  
Maria Zacchia ◽  
Mahsa Dadar ◽  
...  
Keyword(s):  
Weight Loss ◽  
Calorie Restriction ◽  
Cue Reactivity ◽  
Brain Regions ◽  
Self Control ◽  
Food Cues ◽  
Control Networks ◽  
Restriction Diet ◽  
Brain Fmri

SummaryInsufficient responses to hypocaloric diets have been attributed to hormonal adaptations that override self-control of food intake. We tested this hypothesis by measuring brain fMRI reactivity to food cues and circulating energy-balance hormones in 24 overweight/obese participants before, and 1 and 3 months after starting a calorie restriction diet. Increased activity in prefrontal regions at month 1 correlated with weight loss at months 1 and 3. Weight loss was also correlated with increased plasma ghrelin and decreased leptin at month 1, and these changes were associated with greater food cue reactivity in reward-related brain regions. However, the reduction in leptin did not counteract weight loss; indeed, it was correlated with further weight loss at month 3. Activation in a network of prefrontal regions associated with self-control could contribute to individual differences in weight loss and maintenance, whereas we failed to find that the hormonal adaptations play a major role.

scholarly journals Adherence and Dietary Composition during Intermittent vs. Continuous Calorie Restriction: Follow-Up Data from a Randomized Controlled Trial in Adults with Overweight or Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1195
Author(s):  
Sarah T. Pannen ◽  
Sandra González Maldonado ◽  
Tobias Nonnenmacher ◽  
Solomon A. Sowah ◽  
Laura F. Gruner ◽  
...  
Keyword(s):  
Weight Loss ◽  
Energy Intake ◽  
Calorie Restriction ◽  
Controlled Trial ◽  
Dietary Composition ◽  
Modest Weight Loss ◽  
Significant Difference ◽  
Weight Loss Strategy ◽  
Overweight Or Obesity

Although intermittent calorie restriction (ICR) has become popular as an alternative weight loss strategy to continuous calorie restriction (CCR), there is insufficient evidence on diet quality during ICR and on its feasibility over longer time periods. Thus, we compared dietary composition and adherence between ICR and CCR in a follow-up analysis of a randomized trial. A total of 98 participants with overweight or obesity [BMI (kg/m2) 25–39.9, 35–65 years, 49% females] were randomly assigned to ICR, operationalized as a “5:2 diet” (energy intake: ~100% on five non-restricted (NR) days, ~25% on two restricted (R) days), or CCR (daily energy intake: ~80%). The trial included a 12-week (wk) intervention phase, and follow-up assessments at wk24, wk50 and wk102. Apart from a higher proportion of energy intake from protein with ICR vs. CCR during the intervention (wk2: p < 0.001; wk12: p = 0.002), there were no significant differences with respect to changes in dietary composition over time between the groups, while overall adherence to the interventions appeared to be good. No significant difference between ICR and CCR regarding weight change at wk102 was observed (p = 0.63). However, self-reported adherence was worse for ICR than CCR, with 71.1% vs. 32.5% of the participants reporting not to or only rarely have followed the regimen to which they were assigned between wk50 and wk102. These results indicate that within a weight management setting, ICR and CCR were equivalent in achieving modest weight loss over two years while affecting dietary composition in a comparable manner.

scholarly journals Uric acid is associated with adiposity factors, especially with fat mass reduction during weight loss in obese children and adolescents

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Yang Niu ◽  
Xue-lin Zhao ◽  
Hui-juan Ruan ◽  
Xiao-meng Mao ◽  
Qing-ya Tang
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Uric Acid ◽  
Children And Adolescents ◽  
Body Fat ◽  
Fat Mass ◽  
Dietary Control ◽  
Obese Children ◽  
Fat Percentage ◽  
Before And After

Abstract Background Current adult studies suggest that uric acid (UA) is associated with body fat, but the relationship in obese children is unclear. Thus, we aim to evaluate the association between uric acid and body composition of obese children. Methods A total of 79 obese children were included in this study, and 52 children (34 boys and 18 girls) underwent a 6-week weight loss camp, including 34 boys and 18 girls. Six-week weight-loss interventions were performed on all participants through aerobic exercise and appropriate dietary control. Laboratory tests and body composition were collected before and after the intervention. Results Before the intervention, correlation analysis demonstrated that uric acid was positively correlated with height, weight, body mass index (BMI), waist circumference, hip circumference, fat mass (FM), and free fat mass (FFM) with adjusting for age and gender (P < 0.05). After 6 weeks of intervention, the participants gained 3.12 ± 0.85 cm in height, body fat percentage decreased by 7.23 ± 1.97%, and lost 10.30 ± 2.83 kg in weight. Univariate and multivariate analysis indicated that uric acid at baseline was associated with FM reduction during weight loss (P < 0.05). Conclusions This study is the first report that uric acid is associated with BMI and FM, and may play an important role in the reduction of FM during weight loss in obese children and adolescents. The interaction between UA and adiposity factors and its underlying mechanisms need to be further explored. Trial registration This study was registered in Clinical Trials.gov (NCT03490448) and approved by the Ethics Committee of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.

scholarly journals Increased Oxidative Stress in Prepubertal Severely Obese Children: Effect of a Dietary Restriction-Weight Loss Program

2005 ◽  
Vol 90 (5) ◽  
pp. 2653-2658 ◽  
Author(s):  
Angelika Mohn ◽  
Mariangela Catino ◽  
Rita Capanna ◽  
Cosimo Giannini ◽  
Maria Marcovecchio ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Weight Loss ◽  
Dietary Restriction ◽  
Weight Loss Program ◽  
Obese Children ◽  
Severely Obese

scholarly journals Simulating long-term human weight-loss dynamics in response to calorie restriction

2018 ◽  
Vol 107 (4) ◽  
pp. 558-565 ◽  
Author(s):  
Juen Guo ◽  
Danielle C Brager ◽  
Kevin D Hall
Keyword(s):  
Weight Loss ◽  
Calorie Restriction
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