scholarly journals Uric acid is associated with adiposity factors, especially with fat mass reduction during weight loss in obese children and adolescents

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Yang Niu ◽  
Xue-lin Zhao ◽  
Hui-juan Ruan ◽  
Xiao-meng Mao ◽  
Qing-ya Tang
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Uric Acid ◽  
Children And Adolescents ◽  
Body Fat ◽  
Fat Mass ◽  
Dietary Control ◽  
Obese Children ◽  
Fat Percentage ◽  
Before And After

Abstract Background Current adult studies suggest that uric acid (UA) is associated with body fat, but the relationship in obese children is unclear. Thus, we aim to evaluate the association between uric acid and body composition of obese children. Methods A total of 79 obese children were included in this study, and 52 children (34 boys and 18 girls) underwent a 6-week weight loss camp, including 34 boys and 18 girls. Six-week weight-loss interventions were performed on all participants through aerobic exercise and appropriate dietary control. Laboratory tests and body composition were collected before and after the intervention. Results Before the intervention, correlation analysis demonstrated that uric acid was positively correlated with height, weight, body mass index (BMI), waist circumference, hip circumference, fat mass (FM), and free fat mass (FFM) with adjusting for age and gender (P < 0.05). After 6 weeks of intervention, the participants gained 3.12 ± 0.85 cm in height, body fat percentage decreased by 7.23 ± 1.97%, and lost 10.30 ± 2.83 kg in weight. Univariate and multivariate analysis indicated that uric acid at baseline was associated with FM reduction during weight loss (P < 0.05). Conclusions This study is the first report that uric acid is associated with BMI and FM, and may play an important role in the reduction of FM during weight loss in obese children and adolescents. The interaction between UA and adiposity factors and its underlying mechanisms need to be further explored. Trial registration This study was registered in Clinical Trials.gov (NCT03490448) and approved by the Ethics Committee of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.

scholarly journals Influence of ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms on body weight and body composition changes after a controlled weight-loss intervention

2016 ◽  
Vol 41 (3) ◽  
pp. 307-314 ◽  
Author(s):  
Barbara Szendrei ◽  
Domingo González-Lamuño ◽  
Teresa Amigo ◽  
Guan Wang ◽  
Yannis Pitsiladis ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Fat Mass ◽  
Current Evidence ◽  
Fat Percentage ◽  
Endurance Strength ◽  
Diet And Exercise ◽  
Before And After ◽  
Physical Activity Recommendations

The β-2 and β-3 adrenergic receptors (ADRB2 and ADRB3) are thought to play a role in energy expenditure and lipolysis. However, the effects of the ADRB2 glutamine (Gln) 27 glutamic acid (glutamate) (Glu) and ADRB3 tryptophan (Trp) 64 arginine (Arg) polymorphisms on weight loss remain controversial. The aim of this study was to investigate the effect of these polymorphisms on changes in weight and body composition during a controlled weight-loss program. One hundred seventy-three healthy overweight and obese participants (91 women, 82 men) aged 18–50 years participated in a 22-week-long intervention based on a hypocaloric diet and exercise. They were randomly assigned to 1 of 4 groups: strength, endurance, strength and endurance combined, and physical activity recommendations only. Body weight, body mass index (BMI), and body composition variables were assessed before and after the intervention. Genetic analysis was carried out according to standard protocols. No effect of the ADRB2 gene was shown on final weight, BMI, or body composition, although in the supervised male group, Glu27 carriers tended to have greater weight (p = 0.019, 2.5 kg) and BMI (p = 0.019, 0.88 kg/m2) reductions than did noncarriers. There seems to be an individual effect of the ADRB3 polymorphism on fat mass (p = 0.004) and fat percentage (p = 0.036), in addition to an interaction with exercise for fat mass (p = 0.038). After the intervention, carriers of the Arg64 allele had a greater fat mass and fat percentage than did noncarriers (p = 0.004, 2.8 kg). In conclusion, the ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms may influence weight loss and body composition, although the current evidence is weak; however, further studies are necessary to clarify their roles.

Comparison of the Effect of Soy protein and Whey protein on Body Composition: A Meta-Analysis of Randomized Clinical Trials

2021 ◽  
pp. 1-27
Author(s):  
Masoome Piri Damaghi ◽  
Atieh Mirzababaei ◽  
Sajjad Moradi ◽  
Elnaz Daneshzad ◽  
Atefeh Tavakoli ◽  
...  
Keyword(s):  
Body Composition ◽  
Whey Protein ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Soy Protein ◽  
Protein Supplementation ◽  
Body Fat Percentage ◽  
Fat Percentage

Abstract Background: Essential amino acids (EAAs) promote the process of regulating muscle synthesis. Thus, whey protein that contains higher amounts of EAA can have a considerable effect on modifying muscle synthesis. However, there is insufficient evidence regarding the effect of soy and whey protein supplementation on body composition. Thus, we sought to perform a meta-analysis of published Randomized Clinical Trials that examined the effect of whey protein supplementation and soy protein supplementation on body composition (lean body mass, fat mass, body mass and body fat percentage) in adults. Methods: We searched PubMed, Scopus, and Google Scholar, up to August 2020, for all relevant published articles assessing soy protein supplementation and whey protein supplementation on body composition parameters. We included all Randomized Clinical Trials that investigated the effect of whey protein supplementation and soy protein supplementation on body composition in adults. Pooled means and standard deviations (SD) were calculated using random-effects models. Subgroup analysis was applied to discern possible sources of heterogeneity. Results: After excluding non-relevant articles, 10 studies, with 596 participants, remained in this study. We found a significant increase in lean body mass after whey protein supplementation weighted mean difference (WMD: 0.91; 95% CI: 0.15, 1.67. P= 0.019). Subgroup analysis, for whey protein, indicated that there was a significant increase in lean body mass in individuals concomitant to exercise (WMD: 1.24; 95% CI: 0.47, 2.00; P= 0.001). There was a significant increase in lean body mass in individuals who received 12 or less weeks of whey protein (WMD: 1.91; 95% CI: 1.18, 2.63; P<0.0001). We observed no significant change between whey protein supplementation and body mass, fat mass, and body fat percentage. We found no significant change between soy protein supplementation and lean body mass, body mass, fat mass, and body fat percentage. Subgroup analysis for soy protein indicated there was a significant increase in lean body mass in individuals who supplemented for 12 or less weeks with soy protein (WMD: 1.48; 95% CI: 1.07, 1.89; P< 0.0001). Conclusion: Whey protein supplementation significantly improved body composition via increases in lean body mass, without influencing fat mass, body mass, and body fat percentage.

scholarly journals Customized Nutritional Intervention to Improve Body Composition, Macronutrient Intake, and Nutritional Behavior in Moderate to Severe Obese Children and Adolescents (P21-063-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Jieun Kim ◽  
YoonMyung Kim ◽  
Kyung-Hee Park ◽  
Han Byul Jang ◽  
Hye-Ja Lee ◽  
...  
Keyword(s):  
Body Composition ◽  
Children And Adolescents ◽  
Body Fat ◽  
Nutritional Intervention ◽  
Care Process ◽  
Evidence Based ◽  
Macronutrient Intake ◽  
Obese Children ◽  
Nutritional Behavior ◽  
Severely Obese

Abstract Objectives Evidence-based customized nutritional interventions are required for effective treatment of moderately-severely obese children and adolescents. Methods Eligible participants who agreed to participate in the intervention program provided informed consent. Customized nutritional intervention was implemented for each participant based on a nutrition care process (NCP) model. Sociodemographic assessment, anthropometrics, biochemical data, health- and dietary-related behaviors, and dietary intake of the study subjects were assessed at baseline and follow-up. All participants engaged in 30-minute nutritional sessions on a monthly basis. Results One hundred three [mean age: 12.4 years, severely obese: n = 69(67%)] children and adolescents were assessed at baseline. After 16 weeks, there were significant improvements in body composition [BMI (−0.8 ± 0.9, P < 0.05), BMI z-score (−0.3 ± 0.2, P < 0.001), body fat (kg) (−1.3 ± 2.1, P < 0.05), and body fat (%)(−1.5 ± 1.9, P < 0.05)] as well as macronutrient intake [total energy intake (kcal)(−563.7 ± 656.8, P < 0.05), energy (%)(−26.5 ± 30.0, P < 0.05) and fat (g)(−28.3 ± 40.6, P < 0.05)] in the adherent group than the non-adherent group. The stage of change according to the transtheoretical model (TTM) was higher in both groups after the intervention (P < 0.001). Conclusions Our customized nutritional intervention resulted in improvements in body composition, macronutrient intake, and nutritional behavior in adherent moderately-severely obese children and adolescents. These results highlight the positive effects of an evidence-based approach as a multidisciplinary intervention for people-centered nutritional care and weight management. Funding Sources This study was funded by Korea Centers for Disease Control and Prevention Grant 2015-ER6401-00.

Does body fat percentage predict post-exercise heart rate response in non-obese children and adolescents?

2017 ◽  
Vol 30 (6) ◽  
pp. 629-633 ◽  
Author(s):  
Tatjana Jezdimirovic ◽  
Valdemar Stajer ◽  
Sasa Semeredi ◽  
Julio Calleja-Gonzalez ◽  
Sergej M. Ostojic
Keyword(s):  
Heart Rate ◽  
Children And Adolescents ◽  
Body Fat ◽  
Heart Rate Recovery ◽  
Autonomic Regulation ◽  
Exercise Heart Rate ◽  
Body Fat Percentage ◽  
Obese Children ◽  
Fat Percentage ◽  
Post Exercise

AbstractBackground:A correlation between adiposity and post-exercise autonomic regulation has been established in overweight and obese children. However, little information exists about this link in non-obese youth. The main purpose of this cross-sectional study was to describe the relationship between body fat percentage (BFP) and heart rate recovery after exercise [post-exercise heart rate (PEHR)], a marker of autonomic regulation, in normal-weight children and adolescents.Methods:We evaluated the body composition of 183 children and adolescents (age 15.0±2.3 years; 132 boys and 51 girls) who performed a maximal graded exercise test on a treadmill, with the heart rate monitored during and immediately after exercise.Results:A strong positive trend was observed in the association between BFP and PEHR (r=0.14; p=0.06). Hierarchical multiple regression revealed that our model explained 18.3% of the variance in PEHR (p=0.00), yet BFP accounted for only 0.9% of the variability in PEHR (p=0.16). The evaluation of the contribution of each independent variable revealed that only two variables made a unique statistically significant contribution to our model (p<0.01), with age contributing 38.7% to our model (p=0.00) while gender accounted for an additional 25.5% (p=0.01). Neither BFP (14.4%; p=0.16) nor cardiorespiratory endurance (5.0%, p=0.60) made a significant unique contribution to the model.Conclusions:Body fatness seems to poorly predict PEHR in our sample of non-obese children and adolescents, while non-modifiable variables (age and gender) were demonstrated as strong predictors of heart rate recovery. The low amount of body fat reported in non-obese young participants was perhaps too small to cause disturbances in autonomic nervous system regulation.

Lipid Profiles of Obese Children and Adolescents Before and After Significant Weight Loss

2000 ◽  
Vol 93 (3) ◽  
pp. 278-282 ◽  
Author(s):  
MELINDA S. SOTHERN ◽  
BRIAN DESPINASSE ◽  
RAYNORDA BROWN ◽  
ROBERT M. SUSKIND ◽  
JOHN N. UDALL ◽  
...  
Keyword(s):  
Weight Loss ◽  
Children And Adolescents ◽  
Lipid Profiles ◽  
Significant Weight Loss ◽  
Obese Children ◽  
Before And After

scholarly journals Esteatose hepática pode comprometer o efeito do exercício físico sobre a composição corporal em crianças e adolescentes obesos?

2017 ◽  
Vol 19 (4) ◽  
pp. 459
Author(s):  
Bruna Thamyres Ciccotti Saraiva ◽  
Paula Alves Monteiro ◽  
Claudia De Carvalho Brunholi ◽  
Marcelo Rodrigues Ribeiro dos Santos ◽  
Diego Giulliano Destro Christofaro ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Exercise ◽  
Children And Adolescents ◽  
Hepatic Steatosis ◽  
Body Fat ◽  
Effect Size ◽  
Repeated Measures ◽  
Subcutaneous Fat ◽  
The Body ◽  
Obese Children

DOI: http://dx.doi.org/10.5007/1980-0037.2017v19n4p459 Physical exercise is one of the forms of prevention and treatment of obesity and associated diseases such as hepatic steatosis. The aim of this study was to analyze whether hepatic steatosis interferes in the effect of physical exercise on the body composition of obese children and adolescents. The sample consists of 40 obese individuals, 13 children (8.17±1.33 years) and 27 adolescents (12.28±1.36 years). Total and segmental body composition was estimated by DEXA. Anthropometric measurements were performed, as well as ultrasound examination of the liver to measure intra-abdominal and subcutaneous fat, and to diagnose hepatic steatosis (HS). The intervention consisted of 20 weeks, with recreational/competitive activities being applied to children and, for adolescents, concurrent training (aerobic and resistance). The Levene’s, repeated-measures ANOVA and effect size tests (ES) by Eta-Squared were performed. It was observed that, although not statistically significant, analyzing the effect size, physical activity in both children (body fat ES effect time= 0.210 and ES effect group= 0.208; fat mass ES effect group = 0.338; fat android ES effect Interaction= 0.267), and adolescents (intra-abdominal fat ES effect group = 0.230) regardless of whether or not HS was effective in reducing body fat. Therefore, exercise was effective in improving the body composition of obese children and adolescents, regardless of HS.

Cocoa-rich chocolate and body composition in postmenopausal women: a randomised clinical trial

2020 ◽  
pp. 1-9 ◽  
Author(s):  
Irene A. Garcia-Yu ◽  
Luis Garcia-Ortiz ◽  
Manuel A. Gomez-Marcos ◽  
Emiliano Rodriguez-Sanchez ◽  
Cristina Lugones-Sanchez ◽  
...  
Keyword(s):  
Body Composition ◽  
Postmenopausal Women ◽  
Body Fat ◽  
Fat Mass ◽  
The Body ◽  
Control Group ◽  
Body Fat Percentage ◽  
Body Fat Mass ◽  
Fat Percentage ◽  
Habitual Diet

Abstract During menopause, women undergo a series of physiological changes that include a redistribution of fat tissue. This study was designed to investigate the effect of adding 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women daily on body composition. We conducted a 6-month, two-arm randomised, controlled trial. Postmenopausal women (57·2 (sd 3·6) years, n 132) were recruited in primary care clinics. Participants in the control group (CG) did not receive any intervention. Those of the intervention group (IG) received 10 g daily of 99 % cocoa chocolate in addition to their habitual diet for 6 months. This quantity comprises 247 kJ (59 kcal) and 65·4 mg of polyphenols. The primary outcomes were the between-group differences in body composition variables, measured by impendancemetry at the end of the study. The main effect of the intervention showed a favourable reduction in the IG with respect to the CG in body fat mass (–0·63 kg (95 % CI –1·15, –0·11), P = 0·019; Cohen’s d = –0·450) and body fat percentage (–0·79 % (95 % CI –1·31, –0·26), P = 0·004; Cohen’s d = –0·539). A non-significant decrease was also observed in BMI (–0·20 kg/m2 (95 % CI –0·44, 0·03), P = 0·092; Cohen’s d = –0·345). Both the body fat mass and the body fat percentage showed a decrease in the IG for the three body segments analysed (trunk, arms and legs). Daily addition of 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women reduces their body fat mass and body fat percentage without modifying their weight.

Variants of the FTO Gene in Obese Children and their Impact on Body Composition and Metabolism before and after Lifestyle Intervention

2011 ◽  
Vol 120 (03) ◽  
pp. 128-131 ◽  
Author(s):  
J. Schum ◽  
G. Blumenstock ◽  
K. Weber ◽  
R. Schweizer ◽  
C. Pfaff ◽  
...  
Keyword(s):  
Body Composition ◽  
Lifestyle Intervention ◽  
Fat Mass ◽  
Child Nutrition ◽  
Obese Children ◽  
Fto Gene ◽  
Significant Difference ◽  
Before And After ◽  
Study Population ◽  
The Impact

AbstractTo investigate the impact of variants of the FTO gene (rs1421085, rs17817449, rs9939609) in obese children before and after lifestyle intervention.Design: Longitudinal, clinical intervention study with an increase in physical activity, and nutritional recommendations based on the ‘Optimized Mixed Diet for German Children and Adolescents’ (Research Institute of Child Nutrition, Germany). Study population: 75 overweight children (40 male, mean BMI 30.4±5.5 kg/m2, mean age 12.6±2.6 years). Measurements: Genotyping by means of a TaqMan SNP genotyping assay. Lean and fat mass were determined by means of DXA.For the whole study population, the 6-month lifestyle intervention resulted in a significant improvement (before intervention minus time point 6 months; mean±SD) in BMI-SDS (0.10±0.17, p<0.001), HOMA (1.41±3.19, p<0.001) and relative fat-mass-SDS (0.09±0.23, p=0.005). Before and after lifestyle intervention, there was no significant difference between heterozygote (n=52) and homozygote (n=21) carriers of the FTO gene in terms of BMI, body composition, and the metabolic profile (Insulin, HOMA, lipids, liver function tests).Variants in the FTO gene are common in obese children but have no impact on body composition and metabolism before and after lifestyle intervention.

scholarly journals Relative Fat Mass as an estimator of whole-body fat percentage among children and adolescents: A cross-sectional study using NHANES

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Orison O. Woolcott ◽  
Richard N. Bergman
Keyword(s):  
Waist Circumference ◽  
Children And Adolescents ◽  
Body Fat ◽  
Fat Mass ◽  
Misclassification Error ◽  
Whole Body ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Cross Sectional ◽  
Overweight Or Obesity

Abstract We evaluated the ability of the Relative Fat Mass (RFM) to estimate whole-body fat percentage among children and adolescents who participated in the National Health and Nutrition Examination Survey from 1999 through 2006 (n = 10,390). The RFM equation for adults (64 − (20 × height/waist circumference) + (12 × sex)) may be used for adolescents 15 to 19 years of age. For children and adolescents 8 to 14 years of age, we suggest a modified RFM equation, named as the RFMp (RFM pediatric): 74 − (22 × height/waist circumference) + (5 × sex). In both equations, sex equals 0 for boys and 1 for girls. RFMp was more accurate than BMI to estimate whole-body fat percentage (measured by dual energy X-ray absorptiometry, DXA) among girls (percentage of estimates that were <20% of measured body fat percentage, 88.2% vs. 85.7%; P = 0.027) and boys 8 to 14 years of age (83.4% vs. 71.0%; P < 0.001). RFM was more accurate than BMI among boys 15 to 19 years of age (82.3% vs. 73.9%; P < 0.001) but slightly less accurate among girls (89.0% vs. 92.6%; P = 0.002). Compared with BMI-for-age percentiles, RFMp had lower misclassification error of overweight or obesity (defined as a DXA-measured body fat percentage at the 85th percentile or higher) among boys 8 to 14 years of age (6.5% vs. 7.9%; P = 0.018) but not girls (RFMp: 8.2%; BMI-for-age: 7.9%; P = 0.681). Misclassification error of overweight or obesity was similar for RFM and BMI-for-age percentiles among girls (RFM: 8.0%; BMI-for-age: 6.6%; P = 0.076) and boys 15 to 19 years of age (RFM: 6.9%; BMI-for-age: 7.8%; P = 0.11). RFMp for children and adolescents 8 to 14 years of age and RFM for adolescents 15 to 19 years of age were useful to estimate whole-body fat percentage and diagnose body fat-defined overweight or obesity.

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