Anemia in Children with Down Syndrome

Background. Iron deficiency anemia impacts on cognitive development. The objective of this study was to determine the prevalence of anemia and iron deficiency in children with Down syndrome and identify risk factors for anemia.Methods. We conducted a prolective cross-sectional study of children attending a multidisciplinary Down syndrome medical center. One hundred and forty nine children with Down syndrome aged 0–20 years were enrolled in the study. Information obtained included a medical history, physical and developmental examination, nutritional assessment, and the results of blood tests.Results. Of the patients studied, 8.1% were found to have anemia. Among the 38 children who had iron studies, 50.0% had iron deficiency. In a multivariate analysis, Arab ethnicity and low weight for age were significantly associated with anemia. Gender, height, the presence of an eating disorder, and congenital heart disease were not risk factors for anemia.Conclusions. Children with Down syndrome are at risk for anemia and iron deficiency similar to the general population. Children with Down syndrome should be monitored for anemia and iron deficiency so that prompt intervention can be initiated.

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Characteristics and risk factors associated with stroke subtypes among adult patients admitted to stroke unit of JUMC

Current Hypertension Reviews ◽

10.2174/1573402115666191121120228 ◽

2019 ◽

Vol 15 ◽

Author(s):

Bekalu Getachew Gebreegziabher ◽

Tesema Etefa Birhanu ◽

Diriba Dereje Olana ◽

Behailu Terefe Tesfaye

Keyword(s):

Risk Factors ◽

Stroke Unit ◽

Medical Center ◽

Data Entry ◽

Public Health Problem ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Factors Associated ◽

Stroke Subtypes

Background: Stroke is a great public health problem in Ethiopia. According to reports, in-hospital stroke mortality was estimated to be 14.7% in Ethiopia. Despite this, in this country researches done on factors associated with stroke sub-types were inadequate. Objective: To assess the Characteristics and risk factors associated with stroke sub-types among patients admitted to JUMC. Methods and materials: A retrospective cross sectional study was conducted from May 2017 to May 2018 in stroke unit of Jimma University Medical Center. A total of 106 medical charts of patients diagnosed with stroke were reviewed. Checklist comprising of relevant variables was used to collect data. SPSS version 21 was employed for data entry and analysis. Chi-square test was used to point-out association and difference among stroke sub-types. The data was presented using text, tables and figures. Result: From a total of 106 patients, 67(63.2%) were men. The mean ± SD of age was 52.67±12.46 years, and no significant association was found. Of all the patients, 59(55.6%) had ischemic strokes and 47(44.4%) had hemorrhagic strokes. The most common risk factor in the patients was alcohol use with a prevalence of 69.9%. Of all the risk factors, only sex, cigarettes smoking and dyslipidemia were significantly associated to sub-types of stroke. Conclusion: Ischemic stroke was the most common subtype of stroke. Sex of patient, cigarette smoking and dyslipidemia are significantly associated with the two stroke subtypes.

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Hepcidin levels can distinguish anemia of chronic disease from iron deficiency anemia in a cross-sectional study of hidradenitis suppurativa patients

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2021.03.090 ◽

2021 ◽

Author(s):

Mondana H. Ghias ◽

Andrew D. Johnston ◽

Kayla M. Babbush ◽

Allison J. Kutner ◽

H. Dean Hosgood ◽

...

Keyword(s):

Chronic Disease ◽

Iron Deficiency ◽

Iron Deficiency Anemia ◽

Hidradenitis Suppurativa ◽

Cross Sectional Study ◽

Deficiency Anemia ◽

Sectional Study ◽

Anemia Of Chronic Disease ◽

Cross Sectional

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Risk factors for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage

Open Medicine ◽

10.1515/med-2020-0169 ◽

2020 ◽

Vol 15 (1) ◽

pp. 598-604

Author(s):

Valentina Opancina ◽

Snezana Lukic ◽

Slobodan Jankovic ◽

Radisa Vojinovic ◽

Milan Mijailovic

Keyword(s):

Risk Factors ◽

Subarachnoid Hemorrhage ◽

Cerebral Vasospasm ◽

Aneurysmal Subarachnoid Hemorrhage ◽

Medical Center ◽

White Blood Cells ◽

Cerebral Aneurysms ◽

International Normalized Ratio ◽

Cross Sectional Study ◽

Cross Sectional

AbstractIntroductionAneurysmal subarachnoid hemorrhage is a type of spontaneous hemorrhagic stroke, which is caused by a ruptured cerebral aneurysm. Cerebral vasospasm (CVS) is the most grievous complication of subarachnoid hemorrhage (SAH). The aim of this study was to examine the risk factors that influence the onset of CVS that develops after endovascular coil embolization of a ruptured aneurysm.Materials and methodsThe study was designed as a cross-sectional study. The patients included in the study were 18 or more years of age, admitted within a period of 24 h of symptom onset, diagnosed and treated at a university medical center in Serbia during a 5-year period.ResultsOur study showed that the maximum recorded international normalized ratio (INR) values in patients who were not receiving anticoagulant therapy and the maximum recorded white blood cells (WBCs) were strongly associated with cerebrovascular spasm, increasing its chances 4.4 and 8.4 times with an increase of each integer of the INR value and 1,000 WBCs, respectively.ConclusionsSAH after the rupture of cerebral aneurysms creates an endocranial inflammatory state whose intensity is probably directly related to the occurrence of vasospasm and its adverse consequences.

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Evaluation of serum electrolyte levels in iron deficiency anemia patients.

The Professional Medical Journal ◽

10.29309/tpmj/2021.28.05.5702 ◽

2021 ◽

Vol 28 (05) ◽

pp. 691-696

Author(s):

Maryam Rafiq ◽

Amna Arooj ◽

Qurrat-ul-Ain Tahir ◽

Nudrat Fayyaz ◽

Afra Samad ◽

...

Keyword(s):

Iron Deficiency ◽

Iron Deficiency Anemia ◽

Serum Ferritin ◽

Cross Sectional Study ◽

Deficiency Anemia ◽

Close Monitoring ◽

Cross Sectional ◽

Mean Values ◽

Medical College ◽

Complete Blood Counts

Objectives: To evaluate electrolytes levels in patients suffering from iron deficiency anemia and to compare it with patients without anemia. Study Design: Descriptive Cross Sectional study. Setting: Department of Pathology, Sahiwal Medical College Sahiwal. Period: November, 2019 to May, 2020. Material & Methods: After taking informed consent, five milliliter of blood was drawn from each patient. Blood sample was analyzed for electrolytes, complete blood counts and serum ferritin levels. Results were compared in normal and iron deficiency anemic groups. Results: A total of 287 clinically anemic suspects including 181 (63.0%) female and 106 (37.0%) male with mean age of patients as 36.11±12.23 were included in this study. A total of 205 (71.4%) of the suspects had anemia whereas frequency of anemia remained higher among females (78.5%) as compared to males (59.5%) in this study. On the basis of serum ferritin levels a total of 178 (62.0%) patients had iron deficiency. Mean values of Sodium (130.41±0.59) and Bicarbonate (24.10±0.31) remained low while mean Potassium (4.33±0.07) and Chloride (103.93±0.47) levels of Iron Deficiency Anemia (IDA) group remained high as compared to non-anemic group. Conclusion: Levels of sodium and bicarbonate are found to be on the lower side while potassium and chloride remained on higher side in patients with Iron deficiency Anemia in this study. Thus these findings indicate close monitoring of electrolytes to evade impediments during management of patients.

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IRON DEFICIENCY ANEMIA;

The Professional Medical Journal ◽

10.29309/tpmj/2019.26.02.3083 ◽

2019 ◽

Vol 26 (02) ◽

Author(s):

Naresh Kumar Seetlani ◽

Khalid Imran ◽

Kashif Sadruddin ◽

Asif Ali ◽

Pyar Ali ◽

...

Keyword(s):

Iron Deficiency ◽

Blood Loss ◽

Iron Deficiency Anemia ◽

Cross Sectional Study ◽

Deficiency Anemia ◽

Outcome Variable ◽

Gi Tract ◽

Cross Sectional ◽

Common Causes ◽

Hospital Stays

Objectives: To determine the frequency of dual lesions detected by Upper and lower GI endoscopies in patients with iron deficiency anemia without obvious blood loss. Study Design: Cross sectional study. Place and Duration of Study: Department of Medicine, Civil Hospital Karachi from 1st Feb 2015 to 31st July 2015. Methodology: A total 163 patients with Iron deficiency anemia (IDA) for duration of 6 months were registered. Upper and lower GI endoscopies were done in all patients. Outcome variable were the presence of dual lesion identified by gastroenterologist during Upper and lower GI endoscopies. All the results were catered in the pre-approved performa and findings were evaluated by SPSS 17. Results: The average age of the patients was 40.64±11.17 years. Frequency of dual lesions detected by Upper and lower GI endoscopies in patients with iron deficiency anemia without obvious blood loss was observed in 38.65% (63/163) cases. Conclusion: Upper GI tract lesion like gastritis, duodenitis, gastric ulcer and duodenal ulcer were the most common causes of IDA without obvious blood loss. However, Dual lesions were not uncommon, thus both procedures (upper and lower GI endoscopies) were required in most (particularly elderly) patients. This can help to provide shorter hospital stays, reduced medical costs and faster decision making for patient care.

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Food Quality and Nutritional Profile of Students from a Public School in Brazil

Food Science and Nutrition Studies ◽

10.22158/fsns.v1n2p87 ◽

2017 ◽

Vol 1 (2) ◽

pp. 87

Author(s):

Loriana L. Teixeira ◽

Estelamar MB Teixeira ◽

Helen Mara Gomes ◽

Lucas Arantes-Pereira

Keyword(s):

Public School ◽

Nutritional Status ◽

Nutritional Assessment ◽

Age Groups ◽

Cross Sectional Study ◽

Cross Sectional ◽

Brazilian Government ◽

Low Weight ◽

Nutritional Transition ◽

Nutritional Status Of Children

<p><em>Feeding is directly related to nutritional status and alterations as obesity and malnutrition, affecting human body and increasing the risk of morbidity and mortality. This study aimed to evaluate the nutritional status of children and adolescents in a public school located in Uberaba MG Brazil by comparing macro and micronutrients on the school menu with PNAE (Brazilian government program) recommendations. A descriptive cross-sectional study including 547 individuals was carried out. Nutritional assessment was done based on anthropometric Z-score analysis. Only the food ingestion made at the school was considered, in order to verify if the meals offered by the school meet the percentage of nutrients recommended by PNAE. With regard to the nutritional status, there was a small proportion of students (0.18%) with low weight (-3 ? Z < -2). There was 15% prevalence of overweight (overweight, obesity, and severe obesity) among students. Menus composition revealed that macronutrients, fiber, and energy intake was lower than that recommended by PNAE for all age groups studied. The prevalence of a considerable number of overweight students is a warning for interventions to prevent obesity. A small percentage of students classified as low weight represents a nutritional transition trend in recent years.</em></p>

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Assessment of Knowledge of Antenatal Mothers Regarding Selected Health Problems of Complicated Pregnancy- A Cross Sectional Study

Biosciences Biotechnology Research Asia ◽

10.13005/bbra/2662 ◽

2018 ◽

Vol 15 (3) ◽

pp. 561-566

Author(s):

R. Johncyrani ◽

Judie Arulappan

Keyword(s):

Risk Factors ◽

Simple Random Sampling ◽

Educational Status ◽

Cross Sectional Study ◽

Health Problems ◽

Deficiency Anemia ◽

Health Seeking ◽

Cross Sectional ◽

Adequate Knowledge ◽

Instructional Manual

Pregnancy and child birth are common and highly important aspects of women’s life. The focus of midwifery is on the care of essentially healthy women, and the care extends to women with social, medical or obstetric risk factors. A descriptive study to assess the knowledge of antenatal mothers on selected health problems complicating pregnancy was conducted. 100 antenatal mothers were selected through simple random sampling method. Among 100 antenatal mothers, 83% had inadequate knowledge and 17% had moderately adequate knowledge. There was highly significant association between the knowledge of antenatal mothers and their demographic variables such as educational status, occupation, and monthly income. It is reported that many of the antenatal mothers were having poor knowledge of selected health problems complicating pregnancy and its clinical manifestation and risk factors. Hence, it is necessary to create awareness among antenatal mothers which might improve their health seeking behaviors. This can be achieved by giving health education to the antenatal mothers. So the researcher had given instructional manual to improve knowledge regarding selected health problems complicating pregnancy which included iron deficiency anemia, gestational diabetes mellitus and pregnancy induced hypertension.

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IRON DEFICIENCY ANEMIA

The Professional Medical Journal ◽

10.29309/tpmj/2014.21.01.1919 ◽

2018 ◽

Vol 21 (01) ◽

pp. 100-105

Author(s):

Hamzullah Khan ◽

Khalid Khan ◽

Fazle Raziq ◽

Aamir Naseem

Keyword(s):

Iron Deficiency ◽

Iron Deficiency Anemia ◽

Cross Sectional Study ◽

Deficiency Anemia ◽

Medical Institute ◽

Cross Sectional ◽

Gynecology And Obstetrics ◽

Study Results ◽

Red Cell Indices ◽

Age Range

Objectives: To determine the importance of the RDW and other red cell indices(MCV, HBG) in the prediction of iron deficiency anemia in third trimester of pregnancy in a tertiarycare hospital of Peshawar. Design: Cross sectional study. Setting: OPD Department ofGynecology and Obstetrics Postgraduate Medical Institute, Lady reading Hospital (PGMI-LRH)st th Peshawar. Period: 1 August 2012- 10 Dec 2012. Material and Methods: A Total of 152 womenattending the centre were included. Necessary information’s were recorded on the questionnaireprepared in accordance with the objectives of the study. Results: A total of 152 women in theirthird trimester presenting to Gynecology and obstetrics department of Lady reading hospitalPeshawar. The age range of the patient was from 20 years to 55 years with mean age of33+3.4years.Out of total 27(18%) were primagravida. Majority of the cases 118(77.6%) werefrom Peshawar, 9% from charsadda, 8% nowshera etc. We also received 2 patients 1.2% fromAfghanistan. Regarding financial status 57 %( 87) females were in upper Class ( i.e. income>20000/month) on recall. Of total 81(53%) of the females were having hemoglobin less than11g/dl and 22% of the women had HCT<32% which as per criteria of the WHO were anemic at thetime of presentation. While 29(19%) patients had low value of MCV (microcytic). Fifty five patients(36.2%) had RDW CV(%) more than 15% which points more towards the microcytic nature ofanemia and more anisocytosis. Conclusions: Fifty five patients (36.2%) had RDW CV(%) morethan 15% which points more towards the microcytic nature of anemia. While 29(19%) patientshad low value of MCV (microcytic). Increased RDW is best indicator for the detection of irondeficiency anemia than MCV. Increased RDW even in the presence of normal MCV can be anearly signal for iron deficiency anemia in pregnacy. Hence RDW is more reliable indicator for irondeficiency especially in pregnancy. Changes in RDW in last trimester is more significant that MCV.

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