scholarly journals Association between Endocrine Disrupting Phenols in Colostrums and Maternal and Infant Health

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
B. Yi ◽  
C. Kim ◽  
M. Park ◽  
Y. Han ◽  
J. Y. Park ◽  
...  

Bisphenol A (BPA) and alkylphenols (APs) are well-known endocrine disrupting chemicals (EDCs) which may threat the next generations' health. We performed biomonitoring of these phenols in colostrums to assess risk of the phenols in breast-fed neonates. Study subjects were the lactating mothers who delivered babies within 2 weeks (N=325; 30.67±3.45 years) and their neonates (N=326; embryonic period, 39.1±1.5 weeks). BPA, nonylphenol (NP), and octylphenol (OP) in colostrums were quantified with LC/MS/MS. Information for environmental exposure sources of the phenols was obtained by questionnaires. As results, median level of BPA in colostrums was 7.8 ng/mL, while most NP or OP was not detected. Regarding health risks of phenols, levels of total NP in colostrums were elevated among sick mothers with toxemia, thyroid disorders, gastritis, and so forth than health mothers (3.51±4.98 versus 2.04±3.71 ng/mL,P=0.02). Dairy products intake and detergents use were positively correlated with total BPA levels (Ps<0.05). In conclusion, we estimate most neonates who are exposed to BPA rather than NP or OP via colostrums and recommend continuous biomonitoring of the phenols to clarify their suspected health risk on neonates and pregnant or gestation mothers.

2016 ◽  
Vol 19 (14) ◽  
pp. 2551-2561 ◽  
Author(s):  
Natalie Holowko ◽  
Mark Jones ◽  
Ilona Koupil ◽  
Leigh Tooth ◽  
Gita Mishra

AbstractObjectiveBreast-feeding is associated with positive maternal and infant health and development outcomes. To assist identifying women less likely to meet infant nutritional guidelines, we investigated the role of socio-economic position and parity on initiation of and sustaining breast-feeding for at least 6 months.DesignProspective cohort study.SettingAustralia.SubjectsParous women from the Australian Longitudinal Study on Women’s Health (born 1973–78), with self-reported reproductive and breast-feeding history (N4777).ResultsWhile 89 % of women (83 % of infants) had ever breast-fed, only 60 % of infants were breast-fed for at least 6 months. Multiparous women were more likely to breast-feed their first child (~90 %v. ~71 % of primiparous women), and women who breast-fed their first child were more likely to breast-feed subsequent children. Women with a low education (adjusted OR (95 % CI): 2·09 (1·67, 2·62)) or a very low-educated parent (1·47 (1·16, 1·88)) had increased odds of not initiating breast-feeding with their first or subsequent children. While fewer women initiated breast-feeding with their youngest child, this was most pronounced among high-educated women. While ~60 % of women breast-fed their first, second and third child for at least 6 months, low-educated women (first child, adjusted OR (95 % CI): 2·19 (1·79, 2·68)) and women with a very low (1·82 (1·49, 2·22)) or low-educated parent (1·69 (1·33, 2·14)) had increased odds of not breast-feeding for at least 6 months.ConclusionsA greater understanding of barriers to initiating and sustaining breast-feeding, some of which are socio-economic-specific, may assist in reducing inequalities in infant breast-feeding.


Author(s):  
Eka Safitri Yanti

Exclusive breastfeeding coverage is still low in Central Bangka Regency. One of the factors causing this is the lack of public knowledge about the management of stored breast milk. Therefore, the team provides counseling on the management of breast milk for Posyandu cadres as well as pregnant and lactating mothers in Tanjung Gunung Village, Central Bangka Regency. After the counseling was carried out, there was a positive impact on the knowledge of mothers about the management of stored breast milk. The statistical results also showed that there was a significant difference between the scores of mothers’ knowledge before and after counseling (p = 0.042). Thus, this activity can be one of the efforts to increase the coverage of exclusive breastfeeding. However, these efforts must also continue to be supported by both the community, community leaders and local health workers. For village officials and the health office, the results of this community service can be used as a medium for policy making, especially on maternal and infant health. Cakupan ASI eksklusif masih tergolong rendah pada Kabupaten Bangka Tengah. Salah satu faktor yang menjadi penyebab hal ini adalah masih rendahnya pengetahuan masyarakat tentang ASI perah. Oleh karena itu, tim pengabdi memberikan penyuluhan tentang manajemen ASI Perah terhadap kader Posyandu serta ibu hamil dan menyusui di Desa Tanjung Gunung Kabupaten Bangka Tengah. Setelah dilakukan penyuluhan tersebut, ada dampak positif terhadap pengetahuan ibu tentang manajemen ASI perah. Hasil statistik juga menunjukkan terdapat perbedaan yang bermakna antara skor pengetahuan ibu sebelum dan sesudah dilakukan penyuluhan (p=0,042). Dengan demikian, kegiatan penyuluhan ini dapat menjadi salah satu dari upaya untuk meningkatkan cakupan ASI eksklusif. Namun, upaya ini juga harus terus didukung baik oleh masyarakat, tokoh masyarakat maupun petugas kesehatan setempat. Bagi perangkat desa dan dinas kesehatan, hasil pengabdian masyarakat ini dapat dijadikan salah satu media untuk pengambilan kebijakan terutama pada kesehatan ibu dan bayi.


2021 ◽  
Vol 11 (20) ◽  
pp. 9358
Author(s):  
Vasiliki Boti ◽  
Vasiliki Kobothekra ◽  
Triantafyllos Albanis ◽  
Ioannis Konstantinou

A simple methodology was developed for the determination of four Endocrine Disrupting Chemicals (EDCs) in dairy products. The EDCs included alkylphenols (4-tert-octylphenol, technical nonylphenol isomers, 4-nonylphenol) and bisphenol-A. The methodology consisted of a quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by liquid chromatography (LC) coupled to the hybrid LTQ/Orbitrap mass spectrometer (MS). The high resolution (HR) analysis provided the required selectivity demonstrating excellent sensitivity and enabled the high-mass accuracy of the analytes within short time of analysis, after a chemometric optimization of the instrument parameters. An experimental design was employed for the estimation of the effect of different parameters on the QuEChERS extraction efficiency to obtain the optimum conditions. Method validation proved that analysis exhibited excellent linearity (R2 > 0.9966), low enough precision (0.6 to 13.3%) and recoveries in the range of 91 to 108%. Limits of detection (LOD < 6.5 ng g−1) and quantification (LOQ < 20 ng g−1) as well as matrix effects (ME) were also evaluated. The optimized method was successfully applied to analyze dairy commodities varying in fat content and packaging material including milk, yogurts and infant formulae. Detected concentration levels (MDL-10.4 ng g−1) for bisphenol-A BPA in milk samples resulted in 0.36% of TDI for the medium case (average BPA concentrations) and 1.15% of TDI for the worst case (maximum BPA concentration).


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