scholarly journals Differential Expression of Myogenic Regulatory Factor Genes in the Skeletal Muscles of TambaquiColossoma macropomum(Cuvier 1818) from Amazonian Black and Clear Water

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
F. A. Alves-Costa ◽  
C. M. Barbosa ◽  
R. C. M. Aguiar ◽  
E. A. Mareco ◽  
M. Dal-Pai-Silva

Hypothesizing that the Amazonian water system differences would affect the expression of muscle growth-related genes in juvenile tambaquiColossoma macropomum(Cuvier 1818), this study aimed to analyze the morphometric data and expression of myogenic regulatory factors (MRFs) in the white and red muscle from tambaqui obtained from clear and black Amazonian water systems. All of the MRF transcript levels (myod,myf5,myogenin, andmrf4) were significantly lower in the red muscle from black water fish in comparison to clear water fish. However, in white muscle, only themyodtranscript level was significantly decreased in the black water tambaqui. The changes in MRFs gene expression in muscle fibers of tambaqui from black water system provide relevant information about the environmental influence as that of water systems on gene expression of muscle growth related genes in theC. macropomum. Our results showed that the physical and chemical water characteristics change the expression of genes that promote muscle growth, and these results may be also widely applicable to future projects that aim to enhance muscle growth in fish that are of substantial interest to the aquaculture.

1993 ◽  
Vol 27 (5-6) ◽  
pp. 61-67 ◽  
Author(s):  
E. Jacobs ◽  
J. W. van Sluis

The surface water system of Amsterdam is very complicated. Of two characteristic types of water systems the influences on water and sediment quality are investigated. The importance of the sewer output to the total loads is different for both water systems. In a polder the load from the sewers is much more important than in the canal basin. Measures to reduce the emission from the sewers are much more effective in a polder. The effect of these measures on sediment quality is more than the effect on water quality. Some differences between a combined sewer system and a separate sewer system can be found in sediment quality.


1999 ◽  
Vol 39 (4) ◽  
pp. 221-231
Author(s):  
A. H. Lobbrecht

The properties of main water ways and infrastructure of rural water systems are often determined by very general design methods. These methods are based on standards that use only little information of the actual water system. Most design methods applied in the Netherlands are based on land use and soil texture. Standards have been developed on the basis of generalized properties of water systems. Details of the actual layout of the water system and the way in which that system is controlled, are usually not incorporated. Present-day dynamic simulation programs and the computer power currently available enable more detailed modeling and incorporation of location-specific data into models. Such models can be used to design the water system and can include real data. A model-based design method is introduced, in which the actual situation of the water system is taken into consideration as well as the way in which the water system is controlled. Stochastics concerning the operation and availability of controlling infrastructure are included in the method. Models can be evaluated by including real data. In this way the actual safety of the water system, for example during floods, can be determined. Water-quantity design criteria can be incorporated as well as water-quality criteria. Application of the method makes it possible to design safe water systems in which excess capacities are avoided and in which all requirements of interest are met. The method, called the ‘dynamic design procedure’, can result in considerable savings for water authorities when new systems have to be designed or existing designs have to be reconsidered.


Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 835
Author(s):  
Mohammadreza Mohammadabadi ◽  
Farhad Bordbar ◽  
Just Jensen ◽  
Min Du ◽  
Wei Guo

Farm-animal species play crucial roles in satisfying demands for meat on a global scale, and they are genetically being developed to enhance the efficiency of meat production. In particular, one of the important breeders’ aims is to increase skeletal muscle growth in farm animals. The enhancement of muscle development and growth is crucial to meet consumers’ demands regarding meat quality. Fetal skeletal muscle development involves myogenesis (with myoblast proliferation, differentiation, and fusion), fibrogenesis, and adipogenesis. Typically, myogenesis is regulated by a convoluted network of intrinsic and extrinsic factors monitored by myogenic regulatory factor genes in two or three phases, as well as genes that code for kinases. Marker-assisted selection relies on candidate genes related positively or negatively to muscle development and can be a strong supplement to classical selection strategies in farm animals. This comprehensive review covers important (candidate) genes that regulate muscle development and growth in farm animals (cattle, sheep, chicken, and pig). The identification of these genes is an important step toward the goal of increasing meat yields and improves meat quality.


2021 ◽  
Vol 757 ◽  
pp. 143896
Author(s):  
Elin Sørhus ◽  
Carey E. Donald ◽  
Denis da Silva ◽  
Anders Thorsen ◽  
Ørjan Karlsen ◽  
...  

2010 ◽  
Vol 5 (1) ◽  
pp. 29-50 ◽  
Author(s):  
Terje Tvedt

AbstractGlobal history has centred for a long time on the comparative economic successes and failures of different parts of the world, most often European versus Asian regions. There is general agreement that the balance changed definitively in the latter part of the eighteenth century, when in continental Europe and England a transformation began that revolutionized the power relations of the world and brought an end to the dominance of agrarian civilization. However, there is still widespread debate over why Europe and England industrialized first, rather than Asia. This article will propose an explanation that will shed new light on Europe’s and England’s triumph, by showing that the ‘water system’ factor is a crucial piece missing in existing historical accounts of the Industrial Revolution. It is argued that this great transformation was not only about modernizing elites, investment capital, technological innovation, and unequal trade relations, but that a balanced, inclusive explanation also needs to consider similarities and differences in how countries and regions related to their particular water systems, and in how they could exploit them for transport and the production of power for machines.


2006 ◽  
Vol 4 (S2) ◽  
pp. 201-240 ◽  
Author(s):  
Michael Messner ◽  
Susan Shaw ◽  
Stig Regli ◽  
Ken Rotert ◽  
Valerie Blank ◽  
...  

In this paper, the US Environmental Protection Agency (EPA) presents an approach and a national estimate of drinking water related endemic acute gastrointestinal illness (AGI) that uses information from epidemiologic studies. There have been a limited number of epidemiologic studies that have measured waterborne disease occurrence in the United States. For this analysis, we assume that certain unknown incidence of AGI in each public drinking water system is due to drinking water and that a statistical distribution of the different incidence rates for the population served by each system can be estimated to inform a mean national estimate of AGI illness due to drinking water. Data from public water systems suggest that the incidence rate of AGI due to drinking water may vary by several orders of magnitude. In addition, data from epidemiologic studies show AGI incidence due to drinking water ranging from essentially none (or less than the study detection level) to a rate of 0.26 cases per person-year. Considering these two perspectives collectively, and associated uncertainties, EPA has developed an analytical approach and model for generating a national estimate of annual AGI illness due to drinking water. EPA developed a national estimate of waterborne disease to address, in part, the 1996 Safe Drinking Water Act Amendments. The national estimate uses best available science, but also recognizes gaps in the data to support some of the model assumptions and uncertainties in the estimate. Based on the model presented, EPA estimates a mean incidence of AGI attributable to drinking water of 0.06 cases per year (with a 95% credible interval of 0.02–0.12). The mean estimate represents approximately 8.5% of cases of AGI illness due to all causes among the population served by community water systems. The estimated incidence translates to 16.4 million cases/year among the same population. The estimate illustrates the potential usefulness and challenges of the approach, and provides a focus for discussions of data needs and future study designs. Areas of major uncertainty that currently limit the usefulness of the approach are discussed in the context of the estimate analysis.


2009 ◽  
Vol 7 (3) ◽  
pp. 465-470 ◽  
Author(s):  
Bernardo Baldisserotto ◽  
Carlos Eduardo Copatti ◽  
Levy Carvalho Gomes ◽  
Edsandra Campos Chagas ◽  
Richard Philip Brinn ◽  
...  

Fishes that live in the Amazonian environment may be exposed to several kinds of waters: "black waters", containing high dissolved organic carbon and acidic pH, "white waters", with ten fold higher Ca2+ concentrations than black waters and neutral pH, and "clear waters", with two fold higher Ca2+ concentrations than black waters and also neutral pH. Therefore, the aim of the present study was to analyze Ca2+ fluxes in the facultative air-breather Hoplosternum littorale (tamoatá) exposed to different Amazonian waters. Fishes were acclimated in well water (similar to clear water) and later placed in individual chambers for Ca2+ fluxes measurements. After 4 h, water from the chambers was replaced by a different type of water. Transfer of tamoatás to ion-poor black or acidic black water resulted in net Ca2+ loss only in the first 2 h of experiment. However, transfer from black or acidic black water to white water led to only net Ca2+ influxes. The results obtained allowed us to conclude that transfer of tamoatás to ion-poor waters (black and acidic black water) led to transient net Ca2+ loss, while the amount of Ca2+ in the ion-rich white water seems adequate to prevent Ca2+ loss after transfer. Therefore, transfer of tamoatás between these Amazonian waters does not seem to result in serious Ca2+ disturbance.


eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Aynur Kaya-Çopur ◽  
Fabio Marchiano ◽  
Marco Y Hein ◽  
Daniel Alpern ◽  
Julie Russeil ◽  
...  

Skeletal muscles are composed of gigantic cells called muscle fibers, packed with force-producing myofibrils. During development the size of individual muscle fibers must dramatically enlarge to match with skeletal growth. How muscle growth is coordinated with growth of the contractile apparatus is not understood. Here, we use the large Drosophila flight muscles to mechanistically decipher how muscle fiber growth is controlled. We find that regulated activity of core members of the Hippo pathway is required to support flight muscle growth. Interestingly, we identify Dlg5 and Slmap as regulators of the STRIPAK phosphatase, which negatively regulates Hippo to enable post-mitotic muscle growth. Mechanistically, we show that the Hippo pathway controls timing and levels of sarcomeric gene expression during development and thus regulates the key components that physically mediate muscle growth. Since Dlg5, STRIPAK and the Hippo pathway are conserved a similar mechanism may contribute to muscle or cardiomyocyte growth in humans.


2021 ◽  
Author(s):  
Pedro Medeiros ◽  
Xi Chen ◽  
Thushara Gunda ◽  
Pieter van Oel ◽  
Giulia Vico ◽  
...  

<p>Dynamic interactions between humans and water have produced unanticipated feedbacks, leading to unsustainability. Current water management practices are unable to capture the relevant spatial and temporal detail of the processes that drive the coupled human-water system. Whereas natural and socioeconomic processes occur slowly, local communities and individuals rapidly respond to ensure supply-demand balance. In this context, agricultural human-water systems stand out, as roughly 70% of global water demand is for agricultural uses. Additionally, interactions between humans and agricultural water systems involve many actors and occur at multiple spatial and temporal scales. For example, farmers are influenced by risk perceptions, and decisions made at the farm level influence regional hydrologic and socioeconomic systems, such as degradation and depletion of water sources as well as prices of crops. Regional behaviors, in turn, affect national and international dynamics associated with crop production and trade of associated investments. On the other hand, global and national priorities can also percolate down to the regional and local levels, influencing farmer decision-making through policies and programs supporting production of certain crops and local investments. Over the last decade, relevant phenomena in the coupled agricultural human-water systems have been described, as the irrigation efficiency paradox, reservoir effect, and river basin closure. Along with the globalization in the food market, attempts have been taken to developing and applying benchmarks for water-efficient food production, focusing on water productivities, water footprints and yield gaps for agricultural products. Furthermore, significant advancements have been achieved by incorporating social dimensions of agricultural human-water systems behavior. Fusion of quantitative datasets via observations, remote sensing retrieval, and physically-based models has been explored. Advancements have also been made to capture qualitative or relatively intangible concepts of community values, norms, and behaviors, by interacting with stakeholders, identifying the most important elements of their environments, and incorporating these insights into socio-hydrological models. Based on what has been done during the IAHS Panta Rhei decade and what we have learned, and despite recent efforts towards a more comprehensive understanding of the effects of human interventions in agricultural systems, several challenges persist, of which we highlight: 1) Identification of the cross-scale causal effect on agricultural water uses; 2) Quantification of human behavior uncertainties shaped by social norms and cultural values; 3) Development of a high spatial and temporal resolution global dataset.</p>


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