scholarly journals Model Organisms and Traditional Chinese Medicine Syndrome Models

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Shuang Ling ◽  
Jin-Wen Xu
Keyword(s):  
Animal Model ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Evaluation System ◽  
Pharmacological Action ◽  
Modern Medicine ◽  
Model Organisms ◽  
Traditional Chinese Medicine Syndrome ◽  
The Difference ◽  
Tcm Syndrome

Traditional Chinese medicine (TCM) is an ancient medical system with a unique cultural background. Nowadays, more and more Western countries due to its therapeutic efficacy are accepting it. However, safety and clear pharmacological action mechanisms of TCM are still uncertain. Due to the potential application of TCM in healthcare, it is necessary to construct a scientific evaluation system with TCM characteristics and benchmark the difference from the standard of Western medicine. Model organisms have played an important role in the understanding of basic biological processes. It is easier to be studied in certain research aspects and to obtain the information of other species. Despite the controversy over suitable syndrome animal model under TCM theoretical guide, it is unquestionable that many model organisms should be used in the studies of TCM modernization, which will bring modern scientific standards into mysterious ancient Chinese medicine. In this review, we aim to summarize the utilization of model organisms in the construction of TCM syndrome model and highlight the relevance of modern medicine with TCM syndrome animal model. It will serve as the foundation for further research of model organisms and for its application in TCM syndrome model.

scholarly journals The Quintessence of Traditional Chinese Medicine: Syndrome and Its Distribution among Advanced Cancer Patients with Constipation

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Chung-Wah Cheng ◽  
Annie O. L. Kwok ◽  
Zhao-Xiang Bian ◽  
Doris M. W. Tse
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Cross Sectional Study ◽  
Advanced Cancer Patients ◽  
Cross Sectional ◽  
Traditional Chinese Medicine Syndrome ◽  
Blood Haemoglobin ◽  
Tcm Syndrome

Constipation is a common problem in advanced cancer patients; however, specific clinical guidelines on traditional Chinese medicine (TCM) syndrome (Zhang) are not yet available. In this cross-sectional study, the TCM syndromes distribution and their common symptoms and signs among 225 constipated advanced cancer patients were determined. Results showed that 127 patients (56.4%) and 7 patients (3.1%) were in deficient and excessive patterns, respectively, while 91 patients (40.4%) were in deficiency-excess complex. The distributions of the five syndromes were:Qideficiency (93.3%),Qistagnation (40.0%), blood (Yin) deficiency (28.9%), Yang deficiency (22.2%), and excess heat (5.8%). Furthermore, age, functional status, and level of blood haemoglobin were factors related to the type of TCM syndrome. A TCM prescription with the functions on replenishing the Deficiency, redirecting the flow ofQistagnation and moistening the dryness caused by the blood (Yin) deficiency can be made for the treatment of advance cancer patients with constipation. Robust trials are urgently needed for further justifying its efficacy and safety in evidence-based approaches.

scholarly journals A Home Efficacy Multi-Modal Intelligent Evaluation System for Wearable Treatment Equipment of Insomnia Through Integration Between Traditional Chinese Medicine and Modern Medicine

2021 ◽  
Vol 38 (5) ◽  
pp. 1469-1476
Author(s):  
Guihong Zhang ◽  
Atsushi Ogihara ◽  
Siyu Zhou ◽  
Xiaotong Yang ◽  
Yujia Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Treatment Efficacy ◽  
Evaluation System ◽  
Modern Medicine ◽  
Home Treatment ◽  
Prediction Ability ◽  
Test Instrument ◽  
Treatment Equipment ◽  
At Home

Wearable treatment equipment has become a hot topic among traditional Chinese medicine (TCM) researchers. The wearable instrument for transcutaneous electrical stimulation therapy (TEST) developed by our research team has unique advantages in treating insomnia induced by the heart disorder due to phlegm and fire (HDPF). However, the treatment efficacy of the instrument has not been verified by multi-modal data, which limits its application at home. In fact, there is no intelligent efficacy evaluation system for the home treatment of insomnia with the instrument. To make up the gap, this paper attempts to build a home efficacy multi-modal intelligent evaluation system (HEMIES) for this wearable TEST instrument, drawing on the latest technologies of medicine and informatics. Taking HDPF-induced insomnia as an example, the authors firstly set up an index system of the HEMIES for HDPF-induced insomnia, and constructed a conceptual model of the HEMIES. Next, the syndrome images of TCM were fused with the text data of modern medicine, and used to evaluate the treatment efficacy and complete the HEMIES. Finally, 33 patients with HDPF-induced insomnia were recruited to treat the disease with the wearable TEST instrument at home. The observed results show that the prediction accuracy rate of the HEMIES was as high as 90.63%, indicating that the system boasts a good prediction ability and a high value for home application. Our HEMIES realizes the objective evaluation of the home treatment efficacy of the wearable TEST instrument in the absence of TCM practitioners, and provides a reference for the efficacy research of other TCM treatment equipment in home treatment.

scholarly journals A Real-World Evidence Study for Distribution of Traditional Chinese Medicine Syndrome and Its Elements on Respiratory Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Fei Xu ◽  
Wengqiang Cui ◽  
Qing Kong ◽  
Zihui Tang ◽  
Jingcheng Dong
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Real World ◽  
Association Rule ◽  
Medical Information ◽  
Real World Data ◽  
Traditional Chinese Medicine Syndrome ◽  
The Core ◽  
Real World Evidence ◽  
Tcm Syndrome

Background. This study aimed to investigate the distribution and characteristics of traditional Chinese medicine (TCM) syndrome and its elements on respiratory diseases (RDs) based on real-world data (RWD). Methods. A real-world study was performed to explore the relationships among TCM syndrome and RDs based on electronic medical information. A total of 26,074 medical records with complete data were available for data analysis. Factor analyses were used to reduce dimensions of TCM syndrome elements and detect common factors. Additionally, cluster analyses were employed to assess combinations of TCM syndrome elements. Finally, association rule analyses were performed to investigate the structures of TCM syndrome elements to estimate the patterns of TCM syndrome. Results. A total of 27 TCM syndromes were extracted from RWD in this work. There were four TCM syndromes with >5.0% frequency based on the distribution frequency. The top five pathogenesis TCM syndrome elements were Tan, Huo, Feng, Qi_Xu, and Han. Factor analysis, cluster analysis, and association rule analysis demonstrated that Tan, Huo, Feng, Qi_Xu, Shen, and Fei were the core TCM syndrome elements. Conclusion. Four common Shi TCM syndromes on RDs were identified: Tan_Re_Yong_Fei, Tan_Zhuo_Zu_Fei, Feng_Re_Fan_Fei, and Feng_Han_Xi_Fei; two core common Xu TCM syndromes (Fei_Shen_Qi_Xu and Fei_Yin_Xu) and two core common Mix TCM syndromes (Fei_Pi_Qi_Xu-Tan_Shi_Yun_Fei and Fei_Shen_Qi_Xu-Tan_Yu_Zu_Fei) were also determined. The core TCM syndrome elements of Tan, Huo, Feng, Qi_Xu, Shen, and Fei were identified in this work.

Opening up a New Field of Modern Medical Research 1

2020 ◽  
Author(s):  
Xiaoguang Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Human Body ◽  
Low Cost ◽  
Acupuncture Point ◽  
Modern Medicine ◽  
Body Structure ◽  
Special Effect ◽  
Special Knowledge ◽  
Opening Up

Modern medicine tells us that the human body is an organism composed of heart, lung, liver, kidney, spleen, stomach, brain, nerves, muscles, bones, blood vessels, blood and so on, while traditional Chinese medicine believes that besides these tissues and organs, the human body still has another part of the structure, traditional Chinese medicine calls them Jing Luo and Shu Xue. Jing Luo means the longitudinal line of the human body and the accompanying net, translated into English Meridians and Collaterals. Shu Xue means holes distributed on Jing Luo and outside Jing Luo, because stimulating Shu Xue's position by acupuncture, massage and other methods can cure diseases, so Shu Xue is translated into English acupuncture point, abbreviated as acupoint or point. Meridians and acupoints are the special knowledge of human body structure in traditional Chinese medicine. Traditional Chinese medicine not only draws the distribution map of the meridians and acupoints in the human body, but also has been using them to treat diseases for thousands of years. There are hundreds of these acupoints, stimulating each one by acupuncture, massage or other methods will have a special effect on the human body and can treat various diseases. But what effect does stimulating every acupoint have on the human body so that it can treat various diseases? The discussion of traditional Chinese medicine is vague and incomprehensible, and can not be proved by experiments. According to the author's research for more than 30 years, this paper makes a clear and accurate exposition of the effects on the human body and diseases that can be treated with acupoint massage. These statements can be proved by experiments, so they are believed to be reliable. It is hoped that meridians, acupoints and massage therapy can be incorporated into modern medicine and become a part of modern medicine after being proved by others through experiments. Massaging acupoints can not only treat many diseases that are difficult to be treated with drugs, but also have simple methods and low cost.

1+1 > 2: Integration of the Host-directed Traditional Chinese Medicine and the Virus-targeted Modern Medicine in Control of COVID-19

2020 ◽  
Vol 7 (2) ◽  
pp. 89-94
Author(s):  
Jianjun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
The World ◽  
Plausible Mechanism

The COVID-19 pandemic has caused millions of infections and hundreds of thousands deaths in the world. The pandemic is still ongoing and no specific antivirals have been found to control COVID-19. The integration of Traditional Chinese Medicine with supportive measures of Modern Medicine has reportedly played an important role in the control of COVID-19 in China. This review summarizes the evidence of TCM in the treatment of COVID-19 and discusses the plausible mechanism of TCM in control of COVID-19 and other viral infectious diseases.

Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review

2012 ◽  
Vol 40 (06) ◽  
pp. 1109-1122 ◽  
Author(s):  
Xijun Wang ◽  
Aihua Zhang ◽  
Hui Sun ◽  
Ping Wang
Keyword(s):  
Systems Biology ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Disease Diagnosis ◽  
Modern Medicine ◽  
Therapeutic Approaches ◽  
Current Trends ◽  
Close Relationship ◽  
The Right ◽  
Personalize Medicine

Traditional Chinese medicine (TCM), an alternative medicine, focuses on the treatment of human disease via the integrity of the close relationship between body and syndrome analysis. It remains a form of primary care in most Asian countries and its characteristics showcase the great advantages of personalized medicine. Although this approach to disease diagnosis, prognosis and treatment has served the medical establishment well for thousands of years, it has serious shortcomings in the era of modern medicine that stem from its reliance on reductionist principles of experimentation and analysis. In this way, systems biology offers the potential to personalize medicine, facilitating the provision of the right care to the right patient at the right time. We expect that systems biology will have a major impact on future personalized therapeutic approaches which herald the future of medicine. Here we summarize current trends and critically review the potential limitations and future prospects of such treatments. Some characteristic examples are presented to highlight the application of this groundbreaking platform to personalized TCM as well as some of the necessary milestones for moving systems biology of a state-of-the-art nature into mainstream health care.

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