scholarly journals Alepidea amatymbicaEckl. & Zeyh.: A Review of Its Traditional Uses, Phytochemistry, Pharmacology, and Toxicology

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
O. A. Wintola ◽  
A. J. Afolayan

Alepidea amatymbicais an important medicinal plant in Southern Africa with a long history of traditional use for the management of conditions like colds, coughs, sore throat, influenza, asthma, and abdominal cramps. Despite the much acclaimed traditional uses of the plant, there is a dearth of scientific information on the review of this plant. Hence, this review is aimed at providing information on the botany, phytochemistry, pharmacology, and toxicology ofA. amatymbica. This review uses all the synonyms of the plant obtained from the plant list. Google scholar, Science Direct, PubMed, and Scopus were made use of in addition to the University of Fort Hare’s online databases. All the phytochemical studies onAlepidea amatymbicaobtained from the literature reported the presence of kaurene-type diterpenoids and their derivatives. Pharmacological areas identified onA. amatymbicafresh and dried extract include antibacterial, antifungal, sedative, astringent, antimalarial, anti-inflammatory, antihelminthes, antihypertensive, anti-HIV, and diuretic activities. Literature search onA. amatymbicarevealed the use of cell line, brine shrimps, and rats for the determination of the toxicity in the plant. Clinical trials and product development to fully exploit the medicinal value are also required to validate its folklore use in traditional medicine.

1999 ◽  
Vol 12 (1) ◽  
pp. 203-225 ◽  
Author(s):  
Hannah Landecker

The ArgumentCell lines and other human-derived biological materials have since 1980 become valuable forms of patentable matter. This paper revisits the much-critiqued legal case Moore v. Regents of the University of Cahfornia, in which John Moore claimed property rights in a patented cell line made from his spleen. Most work to date has critiqued the text of the decision and left the relevant scientific and technical literature unexamined. By mapping out the construction of discontinuity and continuity between human body and cell line in this literature, this paper provides a novel critique of the Moore case regarding the source and mobilization of scientific information in the decision. At the same time, the elisions of the case are used to move to a larger set of questions. Comparative material from the history of the first widely used cell line, HeLa, and a discussion of the relation of the scientific and economic value of cell lines, are aimed at analysis of how new objects such as patented human cell lines come into existence through science and law, and what kinds of definitions and practices make them valued objects of contention in the first place.


2013 ◽  
Vol 2013 ◽  
pp. 1-51 ◽  
Author(s):  
Arlene P. Bartolome ◽  
Irene M. Villaseñor ◽  
Wen-Chin Yang

There are 230 to 240 knownBidensspecies. Among them,Bidens pilosais a representative perennial herb, globally distributed across temperate and tropical regions.B. pilosahas been traditionally used in foods and medicines without obvious adverse effects. Despite significant progress in phytochemical and biological analyses ofB. pilosaover the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. The present review aims to summarize up-to-date information on the phytochemistry, pharmacology, and toxicology ofB. pilosafrom the literature. In addition to botanical studies and records of the traditional use ofB. pilosain over 40 diseases, scientific studies investigating the potential medicinal uses of this species and its constituent phytochemicals for a variety of disorders are presented and discussed. The structure, bioactivity, and likely mechanisms of action ofB. pilosaand its phytochemicals are emphasized. Although some progress has been made, further rigorous efforts are required to investigate the individual compounds isolated fromB. pilosato understand and validate its traditional uses and develop clinical applications. The present review provides preliminary information and gives guidance for further basic and clinical research into this plant.


2020 ◽  
Vol 23 (5) ◽  
pp. 970-976
Author(s):  
Khaytgul Mukhammedovba Pirmedova

Tashkent State Law University is the basic higher educational and scientific-methodological institution for the training of legal personnel in Uzbekistan. The formation and development of the Information Resource Center of Tashkent State Law University is inextricably linked with the history of the formation and development of the university itself.The author talks about the activities of the Information Resource Center, which is the most important link in the academic system of scientific information of the republic on legal sciences.


2014 ◽  
Vol 42 (01) ◽  
pp. 23-35 ◽  
Author(s):  
Soheil Zorofchian Moghadamtousi ◽  
Muhamad Noor Alfarizal Kamarudin ◽  
Chim Kei Chan ◽  
Bey Hing Goh ◽  
Habsah Abdul Kadir

Loranthus parasiticus Merr (L. parasiticus) is a member of Loranthaceae family and is an important medicinal plant with a long history of Chinese traditional use. L. parasiticus, also known as Sang Ji Sheng (in Chinese), benalu teh (in Malay) and baso-kisei (in Japanese), is a semiparasitic plant, which is mostly distributed in the southern and southwestern regions of China. This review aims to provide a comprehensive overview of the ethnomedicinal use, phytochemistry and pharmacological activity of L. parasiticus and to highlight the needs for further investigation and greater global development of the plant's medicinal properties. To date, pharmacological studies have demonstrated significant biological activities, which support the traditional use of the plant as a neuroprotective, tranquilizing, anticancer, immunomodulatory, antiviral, diuretic and hypotensive agent. In addition, studies have identified antioxidative, antimutagenic, antiviral, antihepatotoxic and antinephrotoxic activity. The key bioactive constituents in L. parasiticus include coriaria lactone comprised of sesquiterpene lactones: coriamyrtin, tutin, corianin, and coriatin. In addition, two proanthocyanidins, namely, AC trimer and (+)-catechin, have been recently discovered as novel to L. parasiticus. L. parasiticus usefulness as a medicinal plant with current widespread traditional use warrants further research, clinical trials and product development to fully exploit its medicinal value.


2012 ◽  
Vol 3 (2) ◽  
pp. 193
Author(s):  
Rosario Mosello ◽  
Maria Grazia Cuoghi ◽  
Diego Fontaneto ◽  
Arianna Orrù ◽  
Clementina Rovati

The paper discusses the relative frequency of topics of study in Italy, through the bibliography compiled by Emilio Corti, an assistant professor at the Zoology Institute of the University of Pavia, covering the period 1850–1933, compared with those obtained from the world literature from the database of Web of Knowledge by the Institute for Scientific Information (ISI) of Thomson Reuters, for the period 1945–2005. Corti's bibliography, which has never been published, is kept in the Archives of the Pavia University Museum and comprises around 5500 papers covering various aspects of hydrobiology, fish and fish farming. Altogether what emerged was a methodical, complex study, providing a wealth of information even though made up solely of bibliographic references. Today it represents a significant source of consultation for anyone interested in the history of science and zoogeography. The comparison of Corti's topics with those of the 1945–2005 period confirmed (1) an overall increase in most research topics, (2) that some research topics, especially related to human activities, increased more than the others, (3) that the studies on malaria showed a peculiar trend, and that (4) organisms-based research did not diminish its importance through time.


2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Renée A. Street ◽  
Jasmeen Sidana ◽  
Gerhard Prinsloo

The genusCichorium(Asteraceae) is made up of six species with major geographical presence in Europe and Asia.Cichorium intybus, commonly known as chicory, is well known as a coffee substitute but is also widely used medicinally to treat various ailments ranging from wounds to diabetes. Although this plant has a rich history of use in folklore, many of its constituents have not been explored for their pharmacological potential. Toxicological data onC. intybusis currently limited. This review focuses on the economic and culturally important medicinal uses ofC. intybus. Traditional uses, scientific validation, and phytochemical composition are discussed in detail.


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