scholarly journals Phytochemistry and Biology of Loranthus parasiticus Merr, a Commonly Used Herbal Medicine

2014 ◽  
Vol 42 (01) ◽  
pp. 23-35 ◽  
Author(s):  
Soheil Zorofchian Moghadamtousi ◽  
Muhamad Noor Alfarizal Kamarudin ◽  
Chim Kei Chan ◽  
Bey Hing Goh ◽  
Habsah Abdul Kadir
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Sesquiterpene Lactones ◽  
Bioactive Constituents ◽  
Comprehensive Overview ◽  
Traditional Use ◽  
Coriaria Lactone ◽  
Medicinal Value ◽  
History Of ◽  
Medicinal Properties

Loranthus parasiticus Merr (L. parasiticus) is a member of Loranthaceae family and is an important medicinal plant with a long history of Chinese traditional use. L. parasiticus, also known as Sang Ji Sheng (in Chinese), benalu teh (in Malay) and baso-kisei (in Japanese), is a semiparasitic plant, which is mostly distributed in the southern and southwestern regions of China. This review aims to provide a comprehensive overview of the ethnomedicinal use, phytochemistry and pharmacological activity of L. parasiticus and to highlight the needs for further investigation and greater global development of the plant's medicinal properties. To date, pharmacological studies have demonstrated significant biological activities, which support the traditional use of the plant as a neuroprotective, tranquilizing, anticancer, immunomodulatory, antiviral, diuretic and hypotensive agent. In addition, studies have identified antioxidative, antimutagenic, antiviral, antihepatotoxic and antinephrotoxic activity. The key bioactive constituents in L. parasiticus include coriaria lactone comprised of sesquiterpene lactones: coriamyrtin, tutin, corianin, and coriatin. In addition, two proanthocyanidins, namely, AC trimer and (+)-catechin, have been recently discovered as novel to L. parasiticus. L. parasiticus usefulness as a medicinal plant with current widespread traditional use warrants further research, clinical trials and product development to fully exploit its medicinal value.

Hidden Potential of Natural Herb Carissa Carandas (Karonda)

2017 ◽  
Vol 3 (2) ◽  
pp. 294-302
Author(s):  
Reshu Virmani ◽  
Tarun Virmani ◽  
Charan Singh ◽  
Geeta Sorout ◽  
Jyoti Gupta
Keyword(s):  
Ascorbic Acid ◽  
Medicinal Plant ◽  
Cardiac Glycosides ◽  
Biological Activities ◽  
Bioactive Constituents ◽  
Medicinal Uses ◽  
Medicinal Value ◽  
Carissa Carandas ◽  
Intestinal Worms ◽  
Natural Herb

Carissa carandas (F. Apocynaceae) is an important fruit commonly known as Karonda ‘Christ’s thorn’ which grows wild in bushes. Carissa carandas is a useful food and medicinal plant of India, found to be widely distributed throughout subtropical and topical regions. The plant has been used as a traditional medicinal plant over thousands of years in the Ayurvedic, Unani, and Homoeopathic system of medicine. The major bioactive constituents, which impart medicinal value to the herb, are alkaloids, flavonoids, saponins and large amounts of cardiac glycosides, triterpenoids, phenolic compounds and tannins. Roots were reported to contain volatile principles including 2-acetyl phenol, lignan, carinol, sesquiterpenes (carissone, carindone), lupeol, β-sitosterol, 16β-hydroxybetulinic acid, α-amyrin, β-sitosterol glycoside, and des-N-methylnoracronycine, whereas leaves were reported to contain triterpenoid constitutes as well as tannins. While, fruits have been reported to contain carisol, epimer of α-amyrin, linalool, β-caryophyllene, carissone, carissic acid, carindone, ursolic acid, carinol, ascorbic acid, lupeol, and β-sitosterol. Traditionally the plant has been used in the treatment of scabies, intestinal worms, pruritus, biliousness and also used as antiscorbutic, anthelmintic. The notable biological activities reported are analgesic, anti inflammatory, anti pyretic, cardiotonic and histamine releasing. This review has been written to presents a detailed survey of the literature on phytochemistry, traditional and biologically evaluated medicinal uses of C. carandas to promote safe and effective herbal treatments to cure a number of diseases.

A Prospective Review on Phyto-pharmacological Aspects of Vitex negundo Linn.

2019 ◽  
Vol 05 ◽  
Author(s):  
Mohd Faisal Khan ◽  
Poonam Arora ◽  
Mahaveer Dhobi
Keyword(s):  
Chlorogenic Acid ◽  
Biological Activities ◽  
Volatile Oil ◽  
Vitex Negundo ◽  
Bioactive Constituents ◽  
Traditional System ◽  
Comprehensive Information ◽  
Medicinal Properties ◽  
Main Components ◽  
Important Drug

Background: Vitex negundo Linn. commonly known as five leave chase tree is an ethnobotanically important drug in traditional system of medicine. The plant is widely distributed in India, China and other Asian and American countries. Objective: The review aims at presenting comprehensive information with respect to ethnopharmacological rele-vance and recent findings on phytochemical and biological activities of Vitex negundo. Method: Literature was collected from various sources such as pubmed, scopus, science direct, and others. Results: Extracts and secondary metabolites of this plant, particularly those from roots and leaves, possess useful pharmacological activities such as anti-inflammatory, antitumor, antioxidant, antimicrobial, galactagogue, antigas-tric, antiflatulant, antiparasitic, analgesic, hepatoprotective and antihypertensive, some of which have been vali-dated scientifically. All parts of plant especially leave and roots contain a large number of bioactive phytoconstitu-ents including flavonoids, iridoids, lignans, volatile oil, terpenes, coumarins, phenolic and steroidal compounds which impart it multiple medicinal properties. Vitexin, isovitexin, viridifol, caffeic acid, chlorogenic acid and iso-chlorogenic acid are the main components. Conclusion: The review emphasises the medicinal importance of Vitex negundo and its bioactive constituents in traditional system of medicine.

scholarly journals Chemical Constituents of Eupatorium japonicum and Anti-Inflammatory, Cytotoxic, and Apoptotic Activities of Eupatoriopicrin on Cancer Stem Cells

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Minh Giang Phan ◽  
Thi Thao Do ◽  
Thi Nga Nguyen ◽  
Thi Viet Huong Do ◽  
Ngoc Phuc Dong ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Human Cancer ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Sesquiterpene Lactones ◽  
No Production ◽  
Bioactive Constituents ◽  
Anti Inflammatory ◽  
First Time ◽  
Eupatorium Japonicum

Eupatorium japonicum Thunb. of the plant family Asteraceae is a popular traditional herb in Vietnam. However, its chemical constituents as well as bioactive principles have not been investigated yet. We investigated the phytochemistry of E. japonicum in Vietnam and isolated seventeen compounds (1–17) including phytosterols, terpenoids, phenolic acids, flavonoids, fatty alcohols, and fatty acids. They were structurally determined by MS and NMR analysis. Except for compounds 6 and 12, all the other compounds were identified for the first time from E. japonicum. Since many sesquiterpene lactones with α-methylene γ-lactone ring are reported as anti-inflammatory and anticancer agents, eupatoriopicrin (10), 1-hydroxy-8-(4,5-dihydroxytigloyloxy)eudesma-4(15),11(13)-dien-6,12-olide (11) were selected among the isolates for biological assays. Compound 10 was identified as the main bioactive sesquiterpene lactone of E. japonicum showing its potent anti-inflammatory and cytotoxic activity through inhibiting NO production and the growth of HepG2 and MCF-7 human cancer cell lines. For the first time, eupatoriopicrin (10) was demonstrated to strongly inhibit NTERA-2 human cancer stem cell (CSC) line in vitro. It is noticeable that the cytotoxicity of eupatoriopicrin against NTERA-2 cells is mediated by its apoptosis-inducing capability of 10 as demonstrated by the results of Hoechst 33342 staining, flow cytometry apoptosis analysis, and caspase-3 activity assays. The biological activities of the main bioactive constituents 1–7, 10, 12, and 15 supported the reported anti-inflammatory and anticancer properties of extracts from E. japonicum.

scholarly journals Flavonoids Profile, Taxonomic Data, History of Cosmetic Uses, Anti-Oxidant and Anti-Aging Potential of Alpinia galanga (L.) Willd

Cosmetics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 89
Author(s):  
Duangjai Tungmunnithum ◽  
Nobuyuki Tanaka ◽  
Ayumi Uehara ◽  
Tsukasa Iwashina
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Taxonomic Status ◽  
Raw Material ◽  
Alpinia Galanga ◽  
Long Time ◽  
History Of ◽  
Data History ◽  
Phytochemical Compounds ◽  
Anti Oxidant

Alpinia galanga is a well-known medicinal plant in Southeast Asia and has been used for a long time as food and medicine. A large number of flavonoid phytochemical compounds have been identified in various parts of this medicinal herb. Flavonoids are commonly known as attractive compounds that can be applied to cosmetic or cosmeceutical product development because of their antioxidant, anti-aging and many other potential biological activities. This recent review aims to illustrate and update the taxonomic status as well as the species description that will be helpful for a rigorous identification and authenticate the raw material or living specimen from A. galanga. The flavonoid phytochemical compounds and the bioactivity of this medicinal plant are also provided. The future perspectives and research directions of A. galanga and its flavonoids are pointed out in this study as well.

scholarly journals Traditional Applications, Phytochemistry, and Pharmacological Activities of Eupatorium lindleyanum DC.: A Comprehensive Review

2020 ◽  
Vol 8 ◽  
Author(s):  
Xueyi Wang ◽  
Shangying Ma ◽  
Feifan Lai ◽  
Yiqi Wang ◽  
Chenghua Lou
Keyword(s):  
Biological Activities ◽  
Sesquiterpene Lactones ◽  
Research Work ◽  
Preclinical Research ◽  
Pharmacological Activities ◽  
Bioactive Substances ◽  
Traditional Use ◽  
Clinical Safety ◽  
Traditional Chinese Herbal Medicine ◽  
Underlying Mechanisms

Eupatorium lindleyanum DC. (EL) has a long history of traditional use in China to cure coughs, chronic bronchitis, lobar pneumonia, and hypertension. Because of this extensive use of EL in traditional medicine, this present review gives a systematic overview of the conventional applications, phytochemistry, and pharmacological effects of the herb. Literature was systematically searched using the scientific databases ScienceDirect, SciFinder, CNKI, Wiley, Baidu Scholar, SpringerLink, PubMed, Web of Science, and other professional websites. Information was also gathered from books on traditional Chinese herbal medicine, the Chinese Pharmacopoeia and Chinese Materia Medica. To date, many preparations of EL have been widely used clinically to treat various diseases of the respiratory system. More than 100 compounds have been isolated from the herb, including triterpenes, sesquiterpenes, sesquiterpene lactones, flavonoids, acyclic diterpenoids, sterols, and so on. Among them, terpenoids are considered to be the most important bioactive substances in EL. The pharmacological functions of EL, including anti-asthmatic, anti-tussive, anti-inflammatory, anti-hyperlipidemic, anti-hypertensive, anti-virus, and anti-tumor activities, have been widely investigated. However, most of the studies are preclinical research. Further studies are required to examine the underlying mechanisms of action. Traditionally, EL is used for treating many diseases, especially respiratory diseases. Unfortunately, up to now, modern studies have not yet well elucidated the conventional usage of EL. Most importantly, its biological activities and the corresponding constituents are still unclear. Moreover, studies on the pharmacokinetics and toxicity of EL are few, so data on the clinical safety of EL are lacking. Taken together, research work on EL is quite preliminary. More in-depth studies of phytochemistry, pharmacological activities, pharmacokinetics, and toxicity of the herb are needed. This review aims to provide valuable information on EL to guide future investigations and applications.

scholarly journals VALIDATION OF TRIBAL CLAIMS ON MORINGA OLEIFERA LAM. USING PHYTOCHEMICAL ANALYSIS

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Getsial Sabatini Wallace J ◽  
S. Naveen Kumar ◽  
V. Negasta Smila ◽  
T. Nivitha ◽  
Stalin Nithaniyal ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Future Research ◽  
Phytochemical Analysis ◽  
Traditional Use ◽  
Phytochemical Study ◽  
Medicinal Uses ◽  
Pharmacological Significance ◽  
History Of

Moringa is a medicinally important genus that has long history of traditional use as a remedy to cure wounds and various ailments such as colds, diabetes, digestive problems etc. In addition, the species is consumed as a source of nutritive food and used as vegetables worldwide. The genus consists of 13 species that have been cultivated throughout Asia and Africa for their multiple purpose use value. The current study is aimed to validate the traditional medicinal uses of Moringa oleifera, provide scientific insights on the phytochemistry, biological activities and thereby correlating its therapeutic potential for future prospects. Analysis of phytochemical profile showed the presence of the major important bioactive compounds (saponin, tannin, flavonoids, phenolics, and reducing sugar) that were assessed in aqueous, methanolic aqueous and acetone-aqueous extracts following standard procedures. This study provides the foundation to explore the tribal medicinal use complemented with the scientific evaluation. Our study reinforce further phytochemical study with advanced technologies for future research opportunities of this species as it is an interesting plant containing commercially important active compounds that enable to determine pharmacological significance, and socio-economic potential.

scholarly journals The Applications of Origanum Vulgare and Its Derivatives in Human, Ruminant and Fish Nutrition – A Review

2020 ◽  
Vol 20 (2) ◽  
pp. 389-407 ◽  
Author(s):  
Mahmoud Alagawany ◽  
Mohamed E. Abd El-Hack ◽  
Mayada R. Farag ◽  
Hazem M. Shaheen ◽  
Mervat A. Abdel-Latif ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Biological Activities ◽  
Health Benefits ◽  
Feed Additive ◽  
Fish Nutrition ◽  
Bioactive Constituents ◽  
Origanum Vulgare ◽  
Urinary Disorders ◽  
Composition And Structure ◽  
Medicinal Properties

AbstractOriganum vulgare L. is an aromatic enduring herb that belongs to Lamiaceae family. The bioactive constituents of this herb, such as carvacrol and thymol possess several medicinal properties, such as antioxidant, antidiabetic, anti-inflammatory, antimicrobial, antiviral, antiparasitic, anti-neoplastic, and immune modulatory. Moreover, it is considered a standard natural, less toxic, and residue free feed additive, that is successfully used in livestock and fish. Additionally, in human, Origanum vulgare is extensively used with promising health benefits against respiratory, digestive and urinary disorders. This review casts light on description, chemical composition and structure of Origanum vulgare, as well as its therapeutic applications in human and its biological activities in ruminants and fish, data that will be possibly useful for physiologists, nutritionists and veterinarians.

scholarly journals AN OVERVIEW OF MEDICINAL VALUE OF CURCUMA SPECIES

2018 ◽  
Vol 11 (12) ◽  
pp. 40 ◽  
Author(s):  
Vanita Kanase ◽  
Farha Khan
Keyword(s):  
Southern China ◽  
Biological Activities ◽  
Curcuma Longa ◽  
Traditional Use ◽  
Medicinal Uses ◽  
Medicinal Value ◽  
The Pacific ◽  
The Family ◽  
The One ◽  
Diabetic Wounds

Curcuma is a genus of about 100 accepted species in the family Zingiberaceae that contains such species as turmeric and Siam tulip. They are native to Southeast Asia, southern China, ISSN (Online): 2319-7064 ISSN (Online): 2319-7064 naturalized in other warm parts of the world such as Tropical Africa, Central America, Florida, and various islands of the Pacific, Indian, and Atlantic Oceans. Few known species of Curcuma with reported pharmacological activity are Curcuma longa, Curcuma aeruginosa, Curcuma pseudomontana, Curcuma aromatica, Curcuma xanthorrhiza, Curcuma zedoaria, Curcuma angustifolia. Among them, C. longa is the one species extensively studied and has ancient traditional medicinal uses. These Curcuma species have been used in traditional medicine as a household remedy for various diseases, including biliary disorders, anorexia, cough, diabetic wounds, hepatic disorders, rheumatism, and sinusitis. For the past few decades, extensive work has been done to establish the biological activities and pharmacological actions of Curcuma species and its extracts. This review article is created with an intention to give an overview on the reported research carried out on the Curcuma species such as anticancer activity, antitumor, antitubercular, antibacterial, antimicrobial, toxicity activity, and wound healing. And also, these Curcuma species can be considered as herbal medicinal plant having a plethora of research opportunities based on its traditional use and biological activity.

scholarly journals Alepidea amatymbicaEckl. & Zeyh.: A Review of Its Traditional Uses, Phytochemistry, Pharmacology, and Toxicology

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
O. A. Wintola ◽  
A. J. Afolayan
Keyword(s):  
Scientific Information ◽  
Traditional Use ◽  
Traditional Uses ◽  
Medicinal Value ◽  
Online Databases ◽  
Brine Shrimps ◽  
History Of ◽  
Pharmacology And Toxicology ◽  
Dried Extract ◽  
The University

Alepidea amatymbicais an important medicinal plant in Southern Africa with a long history of traditional use for the management of conditions like colds, coughs, sore throat, influenza, asthma, and abdominal cramps. Despite the much acclaimed traditional uses of the plant, there is a dearth of scientific information on the review of this plant. Hence, this review is aimed at providing information on the botany, phytochemistry, pharmacology, and toxicology ofA. amatymbica. This review uses all the synonyms of the plant obtained from the plant list. Google scholar, Science Direct, PubMed, and Scopus were made use of in addition to the University of Fort Hare’s online databases. All the phytochemical studies onAlepidea amatymbicaobtained from the literature reported the presence of kaurene-type diterpenoids and their derivatives. Pharmacological areas identified onA. amatymbicafresh and dried extract include antibacterial, antifungal, sedative, astringent, antimalarial, anti-inflammatory, antihelminthes, antihypertensive, anti-HIV, and diuretic activities. Literature search onA. amatymbicarevealed the use of cell line, brine shrimps, and rats for the determination of the toxicity in the plant. Clinical trials and product development to fully exploit the medicinal value are also required to validate its folklore use in traditional medicine.

scholarly journals Acalypha indica L. - an Important Medicinal Plant: A Brief Review of Its Pharmacological Properties and Restorative Potential

2020 ◽  
pp. 1-10
Author(s):  
Sudhakar Chekuri ◽  
Lali Lingfa ◽  
Shivaprasad Panjala ◽  
K. C. Sai Bindu ◽  
Roja Rani Anupalli
Keyword(s):  
Medicinal Plant ◽  
Review Article ◽  
Synthetic Chemicals ◽  
Medicinal Value ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Medicinal Properties ◽  
Important Medicinal Plant ◽  
Acalypha Indica

Medicinal plants are moving from border to mainstream use with a more number of people seeking treatment and health approaches free from side effects caused by synthetic chemicals. India officially recognizes over 3500 plants for their medicinal value. It is generally estimated that over 6000 plants in India are in use in folk, traditional and herbal medicine. This review article aims to provide a comprehensive review on the phytochemical and various pharmacological aspects of Acalypha indica. This plant widely used in traditional medicinal system of India and many other countries has been reported to possess anti-cancer, anti-diabetic, anti-oxidant, anti-bacterial, antifungal hepatoprotective, anti-inflammatory, and also used to check anti-ulcers and wounds healing. It is known as a rich source of glycosides, flavanoids and tannins. The medicinal properties and therapeutic uses of Acalypha indica and its secondary metabolites investigations prove its importance as a valuable medicinal plant.

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