scholarly journals Physical Activity, Aerobic Capacity, and Total Antioxidant Capacity in Healthy Men and in Men with Coronary Heart Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Anna Gawron-Skarbek ◽  
Jacek Chrzczanowicz ◽  
Joanna Kostka ◽  
Dariusz Nowak ◽  
Wojciech Drygas ◽  
...  

Objective.The purpose of the study was to assess total antioxidant capacity (TAC) of blood serum in relation with habitual leisure time physical activity (LTPA) and aerobic capacity in a group of 90 men with coronary heart disease (CHD) aged 34.8–77.0 years and in 90 age-matched peers without CHD.Methods.Two spectrophotometric methods were applied to assess TAC: Ferric Reducing Ability of Serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH) tests. Aerobic capacity was expressed as physical working capacity at 85% of the maximal heart rate (PWC85%HRmax).Results. CHD patients had higher values of TACFRAS (1.37±0.28versus1.27±0.23 mmol FeCl2·L−1;P<0.05) but there were no group differences for TAC-DPPH and for uric acid (UA). Negative correlation was found between LTPA (also when calculated per kg of body mass) and TAC-DPPH in CHD patients. In CHD patients, TAC-FRAS and UA were lower in subjects with higher aerobic capacity expressed asPWC85%HRmax/kg. Those associations were not found in healthy men.Conclusions. We conclude that TAC of blood serum is moderately adversely related to LTPA and aerobic capacity in patients with CHD. UA, as the main determinant of serum TAC, may be partially responsible for those associations.

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Anna Gawron-Skarbek ◽  
Jacek Chrzczanowicz ◽  
Joanna Kostka ◽  
Dariusz Nowak ◽  
Wojciech Drygas ◽  
...  

Whether the incidence of coronary heart disease (CHD) is related to a decrease in total antioxidant capacity (TAC) has not yet been completely clarified. We assessed TAC of blood serum in a group of 163 men with CHD aged 34.8–77.0 years and in 163 age-matched peers without CHD. Two spectrophotometric methods were applied to assess TAC: ferric reducing ability of serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH) tests. In the CHD group, multivariate analysis revealed that uric acid (UA), triglycerides, and systolic blood pressure contributed independently to the TAC-FRAS variance. TAC-DPPH was favorably predicted by UA concentration, but negatively so by current smoking and glucose levels. In men without CHD, UA was the only independent determinant of both TAC-FRAS and TAC-DPPH. Presence of CHD was not an independent predictor of TAC—observed between-group differences (higher TAC in CHD patients) disappeared after adjustment for other confounders. We conclude that UA is the main determinant of TAC of blood serum in men. TAC is not directly influenced by age or CHD but is related to several indices of overweight/obesity and laboratory measures of metabolic syndrome, especially in patients with CHD.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Stavros A. Kavouras ◽  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Christina Chrysohoou ◽  
Giannis Arnaoutis ◽  
...  

We studied the association of physical activity and adherence to the Mediterranean diet, in total antioxidant capacity (TAC). A random sample of 1514 men and 1528 women was selected from Attica region. Physical activity was assessed with a translated version of the validated “International Physical Activity Questionnaire” (iPAQ), and dietary intake through a validated Food Frequency Questionnaire (FFQ). Adherence to the Mediterranean diet was assessed by the MedDietScore that incorporated the inherent characteristics of this diet. TAC was positively correlated with the degree of physical activity (P<.05). TAC was also positively correlated with MedDietScore (r=0.24,P<.001). Stratified analysis by diet status revealed that the most beneficial results were observed to highly active people as compared to inactive, who also followed the Mediterranean diet (288  ±  70 μmol/L,230  ±  50 μmol/L, resp.), after adjusting for various confounders. Increased physical activity and greater adherence to the Mediterranean diet were associated with increased total antioxidant capacity.


2007 ◽  
Vol 17 (8) ◽  
pp. 590-597 ◽  
Author(s):  
Christina Chrysohoou ◽  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Ioannis Skoumas ◽  
Lambros Papademetriou ◽  
...  

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5812-P5812
Author(s):  
E. Oikonomou ◽  
G. Siasos ◽  
C. Chrysohoou ◽  
D. Tousoulis ◽  
M. Zaromitidou ◽  
...  

2003 ◽  
Vol 6 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Jing Ma, ◽  
Zhaomin Liu, ◽  
Wenhua Ling

AbstractObjective:To investigate the relationship between different types and levels of physical activity and cardiovascular disease risk factors, including oxidative stress, blood lipids and insulin resistance, in a healthy female population in China.Method:Healthy women (n= 761) aged 35 to 65 years participated in this study. The habitual physical activity was evaluated by self-administered questionnaire (MOSPA). The dietary intakes of nutrients were calculated from 3-day recall records. Anthropometric data of each subject were measured, fasting blood samples were taken, and erythrocytes and serum were prepared for the measurement of erythrocyte superoxide dismutase activity, serum malondialdehyde, total antioxidant capacity, insulin, glucose and lipids (total cholesterol, triglycerides, apolipoprotein AI (apo A) and apolipoprotein B (apo B)) concentrations.Results:Low level of physical activity was related to a lower concentration of serum apo B, and higher energy expenditure from household physical activity had a reverse relationship with serum apo B and triglyceride levels. In the group with moderate occupational energy expenditure, the concentration of serum triglycerides was lower, but that of high-density lipoprotein was higher. Moderate energy expenditure (less than 1700 kcal day−1) from leisure-time physical activity was positively related to total antioxidant capacity and insulin sensitivity. However, heavy occupational physical activity may be not beneficial for the cardiovascular system.Conclusion:This study indicates that leisure-time, moderate occupational and household physical activity levels decreased risk factors for cardiovascular disease.


2012 ◽  
Vol 44 (4) ◽  
pp. 575-582 ◽  
Author(s):  
JACEK CHRZCZANOWICZ ◽  
ANNA GAWRON-SKARBEK ◽  
JOANNA KOSTKA ◽  
DARIUSZ NOWAK ◽  
WOJCIECH DRYGAS ◽  
...  

2019 ◽  
Vol 25 (3) ◽  
pp. 158-171
Author(s):  
Mahnaz Chatraei Azizabadi ◽  
◽  
Parvaneh NazarAli ◽  
Mehdi Hedayati ◽  
Azam Ramezankhani ◽  
...  

Aims: Certain exercises can develop the antioxidant system. Fenugreek supplementation containing antioxidant capacity and minerals may increase the benefits of exercises. The current study aimed at investigating the effect of Pilates training with fenugreek supplement on Total Antioxidant Capacity (TAC) and minerals in active women. Methods & Materials: The current study was with a quasi-experimental design was conducted on 36 active women aged 21-28 years randomly assigned into four groups: training, supplement, training plus supplement, and control. The training groups performed six weeks of Pilates training with the intensity of 60%-80% of maximal heart rate, three times a week for six weeks. Supplement groups received 500 mg fenugreek seeds daily for six weeks. Before and after the intervention, TAC and minerals (calcium, phosphorus, and iron) were measured. Data were analyzed by two-way ANOVA, Tukey post hoc test, and paired t-test at significant levels of P<0.05. Findings: In two variables, TAC and calcium, the time effect was significant, in other words, regardless of the group factor, there were significant differences between the post-test and pre-test of TAC and calcium variables in the experimental groups. The interaction of time-group was significant in TAC variable (P<0.05). The effect of the group was not significant in any of the variables. Conclusion: The obtained results suggested that one period of Pilates training and the use of fenugreek supplement alone and in combination could possibly prevent oxidative stress induced by exercise and could be effective in enhancing TAC and increasing calcium levels in active women.


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