scholarly journals The Effects of Red Fruit (Pandanus Conoideus Lam) Supplementation on Total Antioxidant Capacity and Creatine Kinase in Rats after Maximal Physical Activity

Author(s):  
Fajar Apollo Sinaga ◽  
Pangondian Hotliber Purba ◽  
Rika Nailuvar Sinaga ◽  
Ramlan Silaban
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Donrawee Leelarungrayub ◽  
Raphiphat Khansuwan ◽  
Prapas Pothongsunun ◽  
Jakkrit Klaphajone

Aim of this study was to evaluate the effects of short-term (7 days) N-acetylcysteine (NAC) at 1,200 mg daily supplementation on muscle fatigue, maximal oxygen uptake (), total antioxidant capacity (TAC), lactate, creatine kinase (CK), and tumor necrotic factor-alpha (TNF-α). Twenty-nine sedentary men (13 controls; 16 in the supplement group) from a randomized control were included. At before and after supplementation, fatigue index (FI) was evaluated in the quadriceps muscle, and performed a graded exercise treadmill test to induce oxidative stress, and as a measure of . Blood samples were taken before exercise and 20 minutes after it at before and after supplementation, to determine TAC, CK, lactate, and TNF-αlevels. Results showed that FI and increased significantly in the supplement group. After exercise decreased the levels of TAC and increased lactate, CK, and TNF-αof both groups at before supplementation. After supplementation, lactate, CK, and TNF-αlevels significantly increased and TAC decreased after exercise in the control group. Whereas the TAC and lactate levels did not change significantly, but CK and TNF-αincreased significantly in the supplement group. Therefore, this results showed that NAC improved the muscle fatigue, , maintained TAC, controlled lactate production, but had no influence on CK and TNF-α.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Stavros A. Kavouras ◽  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Christina Chrysohoou ◽  
Giannis Arnaoutis ◽  
...  

We studied the association of physical activity and adherence to the Mediterranean diet, in total antioxidant capacity (TAC). A random sample of 1514 men and 1528 women was selected from Attica region. Physical activity was assessed with a translated version of the validated “International Physical Activity Questionnaire” (iPAQ), and dietary intake through a validated Food Frequency Questionnaire (FFQ). Adherence to the Mediterranean diet was assessed by the MedDietScore that incorporated the inherent characteristics of this diet. TAC was positively correlated with the degree of physical activity (P<.05). TAC was also positively correlated with MedDietScore (r=0.24,P<.001). Stratified analysis by diet status revealed that the most beneficial results were observed to highly active people as compared to inactive, who also followed the Mediterranean diet (288  ±  70 μmol/L,230  ±  50 μmol/L, resp.), after adjusting for various confounders. Increased physical activity and greater adherence to the Mediterranean diet were associated with increased total antioxidant capacity.


1999 ◽  
Vol 96 (1) ◽  
pp. 105-115 ◽  
Author(s):  
R. CHILD ◽  
S. BROWN ◽  
S. DAY ◽  
A. DONNELLY ◽  
H. ROPER ◽  
...  

This study investigated the effects of chronic muscle inflammation on indices of antioxidant status and muscle injury after eccentric exercise. Eight subjects each performed 70 maximal voluntary eccentric muscle actions on an isokinetic dynamometer, using the knee extensors of a single leg. Venous blood samples were collected into serum and EDTA tubes 5 and 3 days before exercise, immediately before exercise, and then again on days 3, 4, 5, 6, 7, 10 and 12 after the bout. Needle biopsies were taken from the vastus lateralis of six subjects, a week before exercise (baseline), and again on days 4 and 7 post-exercise. The concentrations of malondialdehyde in plasma and muscle were used as markers of lipid peroxidation. Creatine kinase activity, β-glucuronidase activity and total antioxidant capacity were determined in serum. In muscle, aqueous and bound total antioxidant capacity, the aqueous sulphydryl concentration, and β-glucuronidase and glucose-6-phosphate dehydrogenase activity were determined. No changes were detected in serum total antioxidant capacity, serum creatine kinase and β-glucuronidase after the baseline biopsy. After exercise serum creatine kinase and β-glucuronidase were elevated although other serum measures were unchanged. In muscle, aqueous and bound total antioxidant capacity, sulphydryls, glucose-6-phosphate dehydrogenase and β-glucuronidase were all elevated. Despite evidence of inflammation in this study, muscle antioxidant status was not compromised, and malondialdehyde was unaltered in muscle and plasma. Therefore, this study provides no evidence that chronic muscle inflammation compromises antioxidant status or increases lipid peroxidation.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Anna Gawron-Skarbek ◽  
Jacek Chrzczanowicz ◽  
Joanna Kostka ◽  
Dariusz Nowak ◽  
Wojciech Drygas ◽  
...  

Objective.The purpose of the study was to assess total antioxidant capacity (TAC) of blood serum in relation with habitual leisure time physical activity (LTPA) and aerobic capacity in a group of 90 men with coronary heart disease (CHD) aged 34.8–77.0 years and in 90 age-matched peers without CHD.Methods.Two spectrophotometric methods were applied to assess TAC: Ferric Reducing Ability of Serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH) tests. Aerobic capacity was expressed as physical working capacity at 85% of the maximal heart rate (PWC85%HRmax).Results. CHD patients had higher values of TACFRAS (1.37±0.28versus1.27±0.23 mmol FeCl2·L−1;P<0.05) but there were no group differences for TAC-DPPH and for uric acid (UA). Negative correlation was found between LTPA (also when calculated per kg of body mass) and TAC-DPPH in CHD patients. In CHD patients, TAC-FRAS and UA were lower in subjects with higher aerobic capacity expressed asPWC85%HRmax/kg. Those associations were not found in healthy men.Conclusions. We conclude that TAC of blood serum is moderately adversely related to LTPA and aerobic capacity in patients with CHD. UA, as the main determinant of serum TAC, may be partially responsible for those associations.


2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5812-P5812
Author(s):  
E. Oikonomou ◽  
G. Siasos ◽  
C. Chrysohoou ◽  
D. Tousoulis ◽  
M. Zaromitidou ◽  
...  

2003 ◽  
Vol 6 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Jing Ma, ◽  
Zhaomin Liu, ◽  
Wenhua Ling

AbstractObjective:To investigate the relationship between different types and levels of physical activity and cardiovascular disease risk factors, including oxidative stress, blood lipids and insulin resistance, in a healthy female population in China.Method:Healthy women (n= 761) aged 35 to 65 years participated in this study. The habitual physical activity was evaluated by self-administered questionnaire (MOSPA). The dietary intakes of nutrients were calculated from 3-day recall records. Anthropometric data of each subject were measured, fasting blood samples were taken, and erythrocytes and serum were prepared for the measurement of erythrocyte superoxide dismutase activity, serum malondialdehyde, total antioxidant capacity, insulin, glucose and lipids (total cholesterol, triglycerides, apolipoprotein AI (apo A) and apolipoprotein B (apo B)) concentrations.Results:Low level of physical activity was related to a lower concentration of serum apo B, and higher energy expenditure from household physical activity had a reverse relationship with serum apo B and triglyceride levels. In the group with moderate occupational energy expenditure, the concentration of serum triglycerides was lower, but that of high-density lipoprotein was higher. Moderate energy expenditure (less than 1700 kcal day−1) from leisure-time physical activity was positively related to total antioxidant capacity and insulin sensitivity. However, heavy occupational physical activity may be not beneficial for the cardiovascular system.Conclusion:This study indicates that leisure-time, moderate occupational and household physical activity levels decreased risk factors for cardiovascular disease.


2012 ◽  
Vol 44 (4) ◽  
pp. 575-582 ◽  
Author(s):  
JACEK CHRZCZANOWICZ ◽  
ANNA GAWRON-SKARBEK ◽  
JOANNA KOSTKA ◽  
DARIUSZ NOWAK ◽  
WOJCIECH DRYGAS ◽  
...  

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S148-S148
Author(s):  
Renata F Oliveira ◽  
Maria Mota ◽  
Jorge Soares ◽  
Zirlene Santos ◽  
Bianca Rosa ◽  
...  

Abstract Oxidative stress is involved in degenerative processes, aging, and diseases. Lifestyle can be change oxidative stress. One of reactive oxygen species targets is polyunsaturated fatty acid, an important cellular membrane component. The aim of this study is to analyse the contribute of lifestyle in lipid peroxidation in over fourty years old women. Were included 60 women whith age ranged between 41 and 82 years old (53.3 ± 9.1 years). Lifestyle were explored doing a food frequency questionnaire, Perceptive Stress Scale (PSS) and International Physical Activity Questionnaire (IPAQ). The functional capacity was determinate by 6-min walking test (cardiorespiratory capacity) and Squat-jump (leg strength and power). Parameters of oxidative stress were determinate from plasma during fasting, lipid peroxidation was evaluated by TBARs, and antioxidant capacity was evaluated by catalase activity and ABTS. Spearman correlation and Multiple Linear Regression model, through Stepwise method, considering TBARs as dependent variable, and age, weight, body mass index, waist circumference, stress perception, physical activity level, total antioxidant capacity, catalase activity, cardiorespiratory capacity, leg strength and power, daily caloric intake, daily fruit, vegetables, coffee/tea, vitamin E and alcohol intake, as independent variable, was performed. Negative correlations were obtained between TBARs and cardiorespiratory capacity (r= -0.35; p=0.026) and between TBARS and ABTS (r= -0.33; p=0.038). Total antioxidant capacity was the model’s first variable (F= 5.50; p = 0.013), explaining 15.3% of TBARS, then cardiorespiratory capacity (F= 5.50; p = 0.047), explaining 10.5% of TBARs The results revealed total antioxidant capacity and cardiorespiratory capacity as predictors to lipid peroxidation damage.


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