scholarly journals Modification of PLGA Nanofibrous Mats by Electron Beam Irradiation for Soft Tissue Regeneration

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Jae Baek Lee ◽  
Young-Gwang Ko ◽  
Donghwan Cho ◽  
Won Ho Park ◽  
Byeong Nam Kim ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Molecular Weight ◽  
Cell Proliferation ◽  
Electron Beam ◽  
Soft Tissue ◽  
Electron Beam Irradiation ◽  
Degradation Behavior ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Electron Beam Radiation

Biodegradable poly(lactide-co-glycolide) (PLGA) has found widespread use in modern medical practice. However, the degradation rate of PLGA should be adjusted for specific biomedical applications such as tissue engineering, drug delivery, and surgical implantation. This study focused on the effect of electron beam radiation on nanofibrous PLGA mats in terms of physical properties and degradation behavior with cell proliferation. PLGA nanofiber mats were prepared by electrospinning, and electron beam was irradiated at doses of 50, 100, 150, 200, 250, and 300 kGy. PLGA mats showed dimensional integrity after electron beam irradiation without change of fiber diameter. The degradation behavior of a control PLGA nanofiber (0 kGy) and electron beam-irradiated PLGA nanofibers was analyzed by measuring the molecular weight, weight loss, change of chemical structure, and fibrous morphology. The molecular weight of the PLGA nanofibers decreased with increasing electron beam radiation dose. The mechanical properties of the PLGA nanofibrous mats were decreased with increasing electron beam irradiation dose. Cell proliferation behavior on all electron beam irradiated PLGA mats was similar to the control PLGA mats. Electron beam irradiation of PLGA nanofibrous mats is a potentially useful approach for modulating the biodegradation rate of tissue-specific nonwoven nanofibrous scaffolds, specifically for soft tissue engineering applications.

A Comparative Study of Electron Beam Radiation Treatment of Quinestrol, Norethindrone and Dienestrol from Wastewater and Toxicity Test

2014 ◽  
Vol 1073-1076 ◽  
pp. 86-89
Author(s):  
Ming Hong Wu ◽  
Jia Ling Li ◽  
Xiang Xin He ◽  
Yan Feng Sun ◽  
Gang Xu ◽  
...  
Keyword(s):  
Electron Beam ◽  
Toxicity Test ◽  
Degradation Rate ◽  
Electron Beam Irradiation ◽  
Radiation Treatment ◽  
Estrogenic Activity ◽  
Acidic Environment ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Electron Beam Radiation

The irradiation degradation of selected estrogens quinestrol (QS) , norethindrone (NET) and dienestrol (DS) were evaluated by electron beam . Processes using electron beam can efficiently degradate QS, NETand DS, usually at reaction dosage lower than 6KGy. Especially remarkable is the high degradation efficiency shown by oxygen saturation which is extremely favored by acidic environment. The order of the degradation rate: DS > NET> QS by different analysis methods such as HPLC. Among electron beam irradiation carried out, higher removal of 90% from solution was observed. In addition, the estrogenic activity of QS, NET and DS was carried out by rotifer test.

scholarly journals Improvements in the Rheological Properties, Impact Strength, and the Biodegradability of PLA/PCL Blend Compatibilized by Electron-Beam Irradiation in the Presence of a Reactive Agent

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Jae Sung Jeon ◽  
Do Hung Han ◽  
Boo Young Shin
Keyword(s):  
Electron Beam ◽  
Rheological Properties ◽  
Electron Beam Irradiation ◽  
Poly Lactic Acid ◽  
Beam Irradiation ◽  
Thermal Stabilities ◽  
Beam Radiation ◽  
Electron Beam Radiation ◽  
Twin Screw ◽  
Compatibilized Blends

In this study, we blended poly(ε-caprolactone) (PCL) into poly(lactic acid) (PLA) and compatibilized these PLA/PCL blends by electron-beam irradiation in the presence of a reactive agent to overcome drawbacks of PLA. To produce compatibilized blends, mixtures of the PLA/PCL/reactive agent were prepared using a twin-screw extruder and exposed to electron-beam radiation at room temperature. Glycidyl methacrylate (GMA) was chosen as the reactive agent to achieve interfacial cross-copolymerization between PLA and PCL phases. Morphological, rheological, and mechanical properties and biodegradabilities of blends were investigated. The morphological study showed significantly improved interfacial adhesion for compatibilized blends, and this was supported by FTIR analysis and a rheological study. Impact strengths, thermal stabilities, and rheological properties of PLA/PCL blends were improved by compatibilization, and the biodegradabilities of compatibilized PLA/PCL blends were greater than that of pure PLA.

scholarly journals Effects of electron beam irradiation on characteristic properties of expanded graphite

2021 ◽  
Vol 11 (1) ◽  
pp. 26-34
Author(s):  
Thu Hong Pham Thi ◽  
Thanh Duoc Nguyen ◽  
Thi Ly Nguyen ◽  
Nhut Khanh Chu ◽  
Van Chung Cao ◽  
...  
Keyword(s):  
Electron Beam ◽  
Electron Beam Irradiation ◽  
Expanded Graphite ◽  
Graphite Powder ◽  
Microwave Treatment ◽  
The Self ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Electron Beam Radiation ◽  
Before And After

Vietnamese graphite powder was irradiated by electron beam radiation (EB) at a range of dose from 0 to 120 kGy, then the graphite samples were expanded with a mixture of H2O2:H2SO4 (1,4:20, v/v) incorporating microwave treatment at 700 W for 30 seconds. The characteristic properties of graphite before and after expansion were evaluated by methods of FTIR, Raman, SEM and XRD. Besides the self-assembled of the graphite’s structure after irradiation, the electron beam radiation also facilitated intercalation processing to make expanded graphite, with coefficient of expansion (Kv) 35% higher than that of pristine graphite.

scholarly journals Effect of Electron Beam Irradiation on Viability of Sarcocystis spp. in Beef

2020 ◽  
Author(s):  
G. Eslami ◽  
S. Peletto ◽  
M. Vakili ◽  
S. Kargar
Keyword(s):  
Electron Beam ◽  
Ribosomal Rna ◽  
Electron Beam Irradiation ◽  
Optimal Dose ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Electron Beam Radiation ◽  
Sarcocystis Spp ◽  
Polymerase Chain ◽  
Zero Time

Background: Sarcocystosis is one of the most distributed parasitic diseases over the world, caused by Sarcocystis spp. In this study, we assessed the effect of electron beam irradiation on the viability of Sarcocystis spp. in beef.  Methods: Experimental beef groups were irradiated by four different electron beam doses of 1, 2, 3, and 4 kGy, at intervals of 0 and 24 h after irradiation, then the samples were transferred inside a sterile microtube containing RNAlater solution and stored at -20 °C till next steps. RNA extractions and cDNA synthesis were done using the related kit in order to detect the presence of the 18S ribosomal RNA region. Relative quantification was carried out using SYBR Green Real time Polymerase Chain Reaction. The statistical analysis was done using SPSS 16.0 by Tukey’s and Kruskal-Wallis tests. Results: Irradiation at zero time was not effective on viability of Sarcocystis, but at 24 h, irradiation doses of 3 (p=0.003) and 4 kGy (p=0.008) caused a significant reduction in Sarcocystis viability. Irradiation doses of 1 and 2 kGy had no significant (p>0.05) effect on Sarcocystis viability reduction. Also, no significant differences (p>0.05) were observed between irradiation doses of 3 and 4 kGy. Conclusion: Electron beam radiation at dose of 3 kGy was effective as the optimal dose for the elimination of Sarcocystis spp. in beef. 

scholarly journals Effects of Gamma and Electron Beam Irradiation on FBG and DFB-FL

2021 ◽  
Vol 2112 (1) ◽  
pp. 012005
Author(s):  
Haifeng Qi ◽  
D Sporea ◽  
A Stancalie ◽  
D Ighigeanu ◽  
D Neguţ ◽  
...  
Keyword(s):  
Electron Beam ◽  
Electron Beam Irradiation ◽  
Gamma Ray ◽  
Radiation Detection ◽  
Distributed Feedback ◽  
Irradiation Condition ◽  
Beam Irradiation ◽  
Irradiation Effects ◽  
Beam Radiation ◽  
Electron Beam Radiation

Abstract This paper reports the comparative experimental study concerning the irradiation effects of gamma-ray and electron beam on fiber Bragg grating (FBG) and distributed feedback fiber laser (DFB-FL). The obvious reflection wavelength shifts are observed for FBGs and DFB-FLs without evident changes in reflectivity and bandwidth under the current experimental irradiation condition, up to 60 kGy gamma radiation and 100 kGy electron beam radiation, respectively. Especially for DFB-FLs, evident attenuation in output power is observed and the rising tendency of the attenuation under increasing irradiation dose is demonstrated as well. Thus, the DFB-FLs are more suitable for radiation detection as compared to passive FBGs.

Effect of Electron Beam Irradiation on the Rheological Properties and Phase Transition Temperature of Poly(N-Vinylcaprolactam)

2020 ◽  
Vol 865 ◽  
pp. 19-24
Author(s):  
Shane C. Halligan ◽  
Kieran A. Murray ◽  
Olivier Vrain ◽  
John G. Lyons ◽  
Luke M. Geever
Keyword(s):  
Phase Transition ◽  
Electron Beam ◽  
Rheological Properties ◽  
Smart Materials ◽  
Electron Beam Irradiation ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Rheological Analysis ◽  
Novel Approach ◽  
Potential Applications

Exposing smart materials to electron beam radiation can induce free radical reactions, such as chain branching or crosslinking, hence enhancing the characteristics of the polymers. Poly (N-vinylcaprolactam) (PNVCL) is a smart material which was synthesised by photopolymerisation. Subsequently, samples were exposed to electron beam technology, where electron beam irradiation was utilised in a novel approach. This led to the modification of the rheological and phase transition properties. Modifying PNVCL through electron beam irradiation opens new avenues and potential applications in the biomedical field. Physically cross-linked PNVCL polymers were prepared by photopolymerisation and samples were subsequently irradiated at different dose ranges (5kGy, 25kGy and 50 kGy). The rheological properties of the PNVCL based samples were established by rheological analysis. Similarly, the PNVCL based sample polymers were further characterised in solution to determine the phase transition of PNVCL.

Modification of Polylactic Acid/ Halloysite Bionanocomposites Using Electron Beam Radiation: Physical, Barrier and Thermal Properties

2020 ◽  
Vol 1002 ◽  
pp. 57-65
Author(s):  
Abdulkader M. Alakrach ◽  
Nik Noriman Zulkepli ◽  
Awad A. Al-Rashdi ◽  
Sam Sung Ting ◽  
Rosniza Hamzah ◽  
...  
Keyword(s):  
Electron Beam ◽  
Polylactic Acid ◽  
Food Packaging ◽  
Electron Beam Irradiation ◽  
Casting Process ◽  
Barrier Properties ◽  
Beam Irradiation ◽  
Beam Radiation ◽  
Electron Beam Processing ◽  
The Impact

This study aimed to develop novel Polylactic acid/ Halloysite (PLA/ HNTs) films which showed better properties when they were used for food packaging. They also displayed better mechanical, barrier, morphological and structural properties when the researchers analysed the impact of the electron beam irradiation on the nanomaterials. They prepared PLA-based nanocomposites containing 5 % w/w of HNTs using the solution casting process. These nanocomposites were further exposed to different ebeam doses (i.e., 0, 20, 40 and 60 kGy). The researchers assessed the effect of the electron beam irradiation on the various properties of the PLA. All the composites showed a homogenous dispersion and distribution of the HNTs in this PLA matrix. Results indicated that the nanocomposites showed better barrier properties in comparison to the neat PLA. Furthermore, the ebeam irradiation could increase the glass-transition temperature and lead to the development of more crosslinks, which increased the degradation temperature and hydrophilicity of the nanocomposites. In this study, the researchers showed that the PLA/HNTs films were effective materials that could be used for the electron beam processing of the pre-packed foods. The best effect was noted for the 20 kGy dosage which was used in the study.

Electron-Beam Irradiation of Cinnamate Films Affords Nanoscale Patterned Substrates for Use in Devices and as Scaffolds in Tissue Engineering

2020 ◽  
Vol 3 (8) ◽  
pp. 7365-7370
Author(s):  
Karl-Philipp Strunk ◽  
N. Maximilian Bojanowski ◽  
Christian Huck ◽  
Markus Bender ◽  
Lisa Veith ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Electron Beam ◽  
Electron Beam Irradiation ◽  
Patterned Substrates ◽  
Beam Irradiation

scholarly journals Electron-Beam Irradiation of the PLLA/CMS/β-TCP Composite Nanofibers Obtained by Electrospinning

Polymers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1593
Author(s):  
Mohd Reusmaazran Yusof ◽  
Roslinda Shamsudin ◽  
Sarani Zakaria ◽  
Muhammad Azmi Abdul Hamid ◽  
Fatma Yalcinkaya ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Electron Beam ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Electron Beam Irradiation ◽  
Composite Nanofibers ◽  
Chemical Interaction ◽  
Slight Reduction ◽  
Beam Irradiation ◽  
Carboxy Methyl

Nanofibrous materials produced by electrospinning processes have potential advantages in tissue engineering because of their biocompatibility, biodegradability, biomimetic architecture, and excellent mechanical properties. The aim of the current work is to study the influence of the electron beam on the poly L-lactide acid/ carboxy-methyl starch/β-tricalcium phosphate (PLLA/CMS/β-TCP) composite nanofibers for potential applications as bone-tissue scaffolds. The composite nanofibers were prepared by electrospinning in the combination of 5% v/v carboxy-methyl starch (CMS) and 0.25 wt% of β-TCP with the PLLA as a matrix component. The composites nanofibers were exposed under 5, 30, and 100 kGy of irradiation dose. The electron-beam irradiation showed no morphological damage to the fibers, and slight reduction in the water-contact angle and mechanical strength at the higher-irradiation doses. The chain scission was found to be a dominant effect; the higher doses of electron-beam irradiation thus increased the in vitro degradation rate of the composite nanofibers. The chemical interaction due to irradiation was indicated by the Fourier transform infrared (FTIR) spectrum and thermal behavior was investigated by a differential scanning calorimeter (DSC). The results showed that the electron-beam-induced poly L-lactide acid/carboxy-methyl starch/β-tricalcium phosphate (PLLA/CMS/β-TCP) composite nanofibers may have great potential for bone-tissue engineering.

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