scholarly journals Valproate Prescribing in Women of Childbearing Age: An Audit of Clinical Practice

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Harini Atturu ◽  
Adedeji Odelola

Background. Evidence is accruing regarding the risks of valproate exposure in women of childbearing age. Recommendations have recently been made for a higher standard of prenatal counselling and prescribing practice in respect of valproate use in this patient group. Aim and Method. A reaudit was carried out to review the standard of clinical discussion around teratogenic risk and pregnancy planning offered to women of child-bearing age prescribed valproate. Case notes and prescription charts of women 45 years old or less were examined and compared with the results of a previous audit in 2005. Results. The use of valproate was increased overall by 64% and there was an 18% increase in off-label valproate use. The rate of clinical discussion carried out during commencement declined from 70% to 35% and at annual review from 50% to 22%. There was less clinical discussion in outpatients and in older patients. More than 40% of doctors surveyed were not confident about giving information to women. Clinical Implication. There is a need for a multidisciplinary approach and action at Healthcare Trust level, to increase awareness and reduce risks associated with valproate prescribing in childbearing women.

Author(s):  
Tatyana Muzychuk ◽  
Svetlana Kulakova ◽  
Yury Suslov ◽  
Anastasia Samoylova

The paper discusses the criminological characteristics of convicted women in penitentiary institutions. It is based on the authors own observations, the analysis of disciplinary practices and crimes of convicted women and the reports of various departments of the Russian Federal Penitentiary Service in 2015-2017. Due to the social function of women, the problem of female crime and its prevention is currently urgent and requires a prompt solution. Most incarcerated women are of child-bearing age, some of them enter the penitentiary system already being pregnant, others become pregnant after extended visits by their husbands. The authors identify and analyze personal and criminological aspects of convicted womens behavior in the context of their motherhood. The paper stresses the behavioral characteristics of convicted women connected with motherhood in the conditions of isolation (the phenomenon of motherhood in the conditions of penitentiary isolation). The penitentiary system should provide the necessary conditions for mothers and their newborn children, which puts an additional specific burden on penitentiary systems employees responsible for achieving the goals of punishment, correction of inmates, observance of regime and prevention of repeat crimes.


Author(s):  
Irshad Begum Shaikh ◽  
Syed Imtiaz Ahmed Jafry ◽  
Syed Muhammad Zulfiqar Hyder Naqvi ◽  
Syeda Nadia Firdous ◽  
Admin

Abstract A cross-sectional survey was conducted from February 2016 to September 2016 to assess knowledge, attitude and practices regarding implants among women of childbearing age visiting Reproductive Health Services Center, Civil Hospital,Karachi. A total of 396 adult non-pregnant married females of child bearing age, from 18 to 49 years old, were interviewed using a structured questionnaire.Only153 (38.6%) of therespondentshad knowledge about implants whereas out of them 122 (79.7%) acquired it from family planning clinics. Almost two third of them (n=267, 67.4%) were in favor of using implants as a contraceptive method. Moreover, 244 (61.6%) of them were of the opinion that if given the choice, they will use implanon though out of total 316 (79.8%) respondents who ever used contraceptives, only 3 (0.9%) used implants.Despiteafavorable attitude, limited knowledge and poor practices of the respondents highlighted the study findings. Keywords: Knowledge, Attitude, Contraception, Progestins, Continuous...


Author(s):  
Yichun Hu ◽  
Min Li ◽  
Jinghuan Wu ◽  
Rui Wang ◽  
Deqian Mao ◽  
...  

Anemia is a public health issue for developing countries, especially for women of childbearing age. The aim of this study was to assess the anemia status and analyze the risk factors for anemia in Chinese childbearing women aged 18–49 years. Hemoglobin concentration was measured by the HiCN method in the Fifth Chinese National Nutrition and Health Survey (CNNHS) in 2010–2012. Age, region type, ethnicity, bodyweight, height, education, season and smoke habit were recorded in unified questionnaires. Latitude was divided by China’s Qinling Mountains and Huaihe River. Childbearing women (28,289) from the CNNHS 2010–2012 were included in this study. The median hemoglobin concentration was 136.2(126.6–145.0) g/L, and it was significantly higher than in CNNHS 2002 (132.5 (122.3–141.6) g/L). The prevalence of anemia was 15.0%, and it was significantly lower than 10 years ago. The logistic regression analysis showed anemia in Chinese childbearing women was specifically related to 30–39 age group (P = 0.004), in spring (P < 0.0001) or in winter (P = 0.006), small and medium-sized cities (P = 0.044) and middle school education level (P = 0.027). The results showed that anemia status among childbearing women was greatly improved over 10 years since 2002, but it was still more severe than the rest of the populations. The nutrition propaganda and education is recommended for childbearing women to help them to improve the nutritional status on their own.


2010 ◽  
Vol 4 (5) ◽  
pp. 217
Author(s):  
Suhartono Suhartono ◽  
Dharminto Dharminto

Wanita bermukim di daerah pertanian berisiko terpajan pestisida yang dapat berakibat hipotiroidisme yang pada kehamilan dapat menyebabkan gangguan tumbuh-kembang janin. Tujuan penelitian ini adalah mengetahui angka kejadian keracunan pestisida dan hipotiroidisme pada wanita usia subur di daerah pertanian. Penelitian ini menggunakan disain penelitian cross-sectional dan 26 WUS terpilih sebagai subjek secara acak. Semua subjek dilakukan pengukurankadar TSH, fT4 dan enzim kolinesterase, sementara kadar T3, UEI, dan Pb darah diukur pada sub-sampel. Penderita dinyatakan keracunan pestisida apabila ditemukan kadar enzim kolinesterase <3,9 μg/L dan dinyatakan hipotiroidisme apabila kadar TSH >4,5 μIU/L. Penelitian ini menemukan rerata kadar kolinesterase adalah 7,26 (±1,28) dengan kisaran nilai 5,33-9,39 μg/L; rerata kadar TSH adalah 5,09 (±6,14), dengan kisaran nilai 0,47-31,73μIU/L; rerata kadar fT4 adalah 15,18 (±2,09), dengan kisaran nilai 8,73-18,87 pmol/L; rerata kadar T3 adalah 1,75 (±0,51), dengan kisaran nilai 1,24-2,95 pmol/L. Prevalensi keracunan pestisida pada WUS 0,0% dan prevalensi hipotiroidisme 46,2%.Kata kunci : Pestisida, hipotiroidisme, wanita usia subur, daerah pertanianAbstractWomen lived in agricultural areas are risk to suffer various disorders due to pesticides exposure such as hypothyroidism. Hypothyroidism causes growth and development disorders of fetus. The aim of the study is to find out the prevalence of pesticide poisoning and hypothyroidism in women of childbearing age in agricultural areas. Cross-sectional study was conducted and 26 women of childbearing age were selected randomly. TSH, fT4 and cholinesterase enzymelevels were measured in all subjects, while levels of T3, UEI and blood Pb were measured in the sub-sample. Pesticide poisoning is determined if the levels of enzymes cholinesterase <3.9 μg/L and determined as hypothyroidism if the TSH >4.5 μIU/L. This study showed that mean of cholinesterase levels was 7.26 (± 1.28), range of values 5.33-9.39 μg/L; mean of TSH levels was 5.09 (± 6.14), range of values 0.47-31.73 μIU/L; mean of fT4 level was 15.18 (±2.09), range of values 8.73-18.87 pmol/L; mean of T3 levels was 1.75 (±0.51), range of values 1.24-2.95 pmol/L. The prevalence of pesticide poisoning in childbearing women was 0.0% and prevalence of hypothyroidism was 46.2%.Key words : Pesticide, hypothyroidism, women of childbearing age, agricultural area


Author(s):  
Trenton Tollefson ◽  
Lynn Liu

Epilepsy is the fourth most common neurologic disorder behind migraine, stroke, and Alzheimer’s disease. The Center for Disease Control (CDC) data estimates about 3.4 million people in the United States have active epilepsy. Approximately 1 million women of childbearing age in the United States have epilepsy, and about 2 to 5 infants of 1000 pregnancies are born to mothers with epilepsy. Therefore, providers should consider additional aspects of epilepsy care unique to women with epilepsy (WWE) of childbearing age such as planning for and care during pregnancy; concern how epilepsy may affect pregnancy and how pregnancy may impact seizure control. Fortunately, more than 90% of pregnant WWE will give birth to healthy infants. Providers should maintain these important items in mind when caring for a WWE of child-bearing age. This chapter focuses on the effects of pregnancy on seizures and the effects of seizures on pregnancy in pregnant WWE.


2010 ◽  
Vol 71 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Liana C. Del Gobbo ◽  
Josephine A. Archbold ◽  
Loren D. Vanderlinden ◽  
Chris S. Eckley ◽  
Miriam L. Diamond ◽  
...  

Pregnant women's fish consumption provides both benefits and risks to the developing fetus. Docosahexaenoic acid (DHA) from fish may enhance fetal neurodevelopment, while methylmercury (MeHg) can have detrimental effects. Dietitians would benefit from information on the frequency with which fish species may be consumed to increase DHA intake among Canadian women of childbearing age, and on minimizing the risks from MeHg, especially for those who consume fish frequently. Eighteen fish species were selected for DHA and mercury analysis from retail markets in the Toronto area. Consumption scenarios using analytical results for these fish species indicate that women of childbearing age can consume nine of 18 fish species every day (14 servings a week) or often (up to four servings a week) and remain below toxicological benchmarks for mercury. Moreover, women can also attain the recommended DHA level by consuming six of those nine fish: four 75-g servings of smelt, porgie, or bluefish a week, or two 75-g servings of milkfish, silver pomfret, or tilapia a day. Our analysis indicates that the DHA level recommended for childbearing women can be attained through fish consumption alone, without the need for supplementation and without posing a risk to the woman (or the fetus) from mercury.


2015 ◽  
Vol 17 (1) ◽  
pp. 14-24
Author(s):  
Shakila Zaman Rima ◽  
SM Moinul Islam ◽  
Nazmun Nahar ◽  
Rawshan Ara ◽  
Ratan Kumar Chakraborty ◽  
...  

Thyroid disorders are prevalent in women of childbearing age and for this reason commonly present in pregnancy and the puerperium. Chronic autoimmune thyroiditis (AIT) is the most common and extensively studied organ-specific autoimmune disorder and it has important consequences on fertility, the occurrence of pregnancy complications and pregnancy outcome. Across sectional analytical study has been carried out on autoimmune thyroiditisamong the women of child bearing age with suspected thyroid disorders in the Centre for Nuclear Medicine & Ultrasound, Mymensingh during the period of July, 2011 to June, 2012.The objectives of the study were to estimate the prevalence of autoimmune thyroiditis in women of child bearing age and to determine the association of autoimmune thyroiditis with thyroid function and thyroid antibody status. In the present study, 100 women of childbearing age (15-45Yrs) with any sorts of suspected thyroid disorders were included. But already diagnosed all follow up cases were excluded from the study. High Resolution Ultrasonography (HRUS) had been taken as principal modality of diagnosis of autoimmune thyroiditis. T3, T4 and TSH were taken as an important indicator for thyroid function status. Serum TM-Ab (Thyroid Microsomal Antibody) level and serum Tg-Ab (Thyroglobulin Antibody) level were measured to see the thyroid antibody status. In the present study, prevalence of autoimmune thyroiditis among the women of childbearing age with suspected thyroid disorders was found 41%. According to the thyroid function status, 65.85% AIT patients were found in hypothyroid state, 29.27% in subclinical hypothyroid state and rest 4.88% were found in euthyroid state. In consideration of thyroid antibody status, 69.23% AIT patients were positive & 30.77% were negative for thyroid autoantibody. This study revealed that there were significant association of AIT with the biochemical hypothyroid state and positive thyroid antibody status DOI: http://dx.doi.org/10.3329/bjnm.v17i1.22487 Bangladesh J. Nuclear Med. 17(1): 14-24, January 2014


2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Avani Shukla ◽  

Background: Young women of reproductive age constitute a significant proportion of India's epilepsy patient population. Doctors take several considerations into account while prescribing antiepileptic drugs (AEDs) to young women to balance the risk of seizures with other concerns. Objective: To understand how doctors perceive various AEDs regarding their safety, efficacy, and other attributes for women of childbearing age. Materials and Methods: This study consisted of a survey designed to understand the usage and perception of 12 antiepileptic drugs in the Indian market. The survey respondents of this study were neurologists, neurosurgeons, and psychiatrists from all over India, from private or government setups, and with different experience and patient load levels. Results: In the study, 93% of all survey respondents indicated that they avoid one or more AEDs in women of childbearing age, making it a significant consideration. This consideration is a specialty split for the second- generation AEDs, Oxcarbazepine, and Levetiracetam. Approximately three times more Neurosurgeons avoid Oxcarbazepine as compared to neurologists and psychiatrists who use this drug. In the case of Levetiracetam, mainly only psychiatrists avoid it for women of reproductive age. Apart from the personal experience of doctors, factors other than teratogenic risks, such as changes in reproductive hormone levels, may have contributed to the observed difference in perception. Conclusion: The study highlights doctors ‘differing perceptions for highly used drugs among all specialties emphasizing the need to determine if such differences in perception exist between other AEDs for various types of patient profiles.


2021 ◽  
Vol 5 (11) ◽  
pp. 110-113
Author(s):  
Jing Huo ◽  
Hongling Fan ◽  
Hui Liu ◽  
Chunjing Zhao ◽  
Xiuli Hou

Objective: To investigate the psychological cognition of women of childbearing age on the use of cosmetics during pregnancy, so as to provide guidance for women of childbearing age to correctly use cosmetics during pregnancy. Methods: A total of 180 women of childbearing age who underwent gynecological examination in Dezhou People’s Hospital from October 2020 to October 2021 were selected as the research subjects. Questionnaires were used to investigate the psychological cognition of women of childbearing age on the use of cosmetics during pregnancy. Results: Among the 180 women of childbearing age, 48 (26.67%) felt that cosmetics cannot be used during pregnancy, 60 (33.33%) felt that it did not matter, and 72 (40.00%) agreed that cosmetics can be used during pregnancy. In addition, urban women, highly educated women, unmarried women, and enterprise employees agreed with the use of special cosmetics for pregnant women or the selective use of cosmetics during pregnancy. Conclusion: Most women of child-bearing age felt that cosmetics can be used during pregnancy; this cognition is related to their education level, occupation, and registered residence.


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