scholarly journals Accuracy of Colposcopically Directed Biopsy: Results from an Online Quality Assurance Programme for Colposcopy in a Population-Based Cervical Screening Setting in Italy

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Mario Sideri ◽  
Paola Garutti ◽  
Silvano Costa ◽  
Paolo Cristiani ◽  
Patrizia Schincaglia ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Multivariate Analysis ◽  
Failure Rate ◽  
Web Application ◽  
Cervical Screening ◽  
Quality Assurance Programme ◽  
Regional Administration ◽  
Biopsy Site ◽  
Increased Risk ◽  
Selection Of

Purpose. To report the accuracy of colposcopically directed biopsy in an internet-based colposcopy quality assurance programme in northern Italy.Methods. A web application was made accessible on the website of the regional Administration. Fifty-nine colposcopists out of the registered 65 logged in, viewed a posted set of 50 digital colpophotographs, classified them for colposcopic impression and need for biopsy, and indicated the most appropriate site for biopsy with a left-button mouse click on the image.Results. Total biopsy failure rate, comprising both nonbiopsy and incorrect selection of biopsy site, was 0.20 in CIN1, 0.11 in CIN2, 0.09 in CIN3, and 0.02 in carcinoma. Errors in the selection of biopsy site were stable between 0.08 and 0.09 in the three grades of CIN while decreasing to 0.01 in carcinoma. In multivariate analysis, the risk of incorrect selection of biopsy site was 1.97 for CIN2, 2.52 for CIN3, and 0.29 for carcinoma versus CIN1.Conclusions. Although total biopsy failure rate decreased regularly with increasing severity of histological diagnosis, the rate of incorrect selection of biopsy site was stable up to CIN3. In multivariate analysis, CIN2 and CIN3 had an independently increased risk of incorrect selection of biopsy site.

QUALITY ASSURANCE OF THERAPEUTIC HEPARIN/ORAL ANTICOAGULANT THERAPY IN A GENERAL TEACHING HOSPITAL

1987 ◽  
Author(s):  
W Brien ◽  
M Inwood ◽  
K Dillon
Keyword(s):  
Quality Assurance ◽  
Teaching Hospital ◽  
Oral Anticoagulant Therapy ◽  
Anticoagulation Therapy ◽  
Heparin Therapy ◽  
Rabbit Brain ◽  
Standard Protocol ◽  
Quality Assurance Programme ◽  
Therapeutic Benefits ◽  
Increased Risk

In preparation for the development of a standard anticoagulation protocol and as part of a quality assurance programme, a retrospective analysis of anticoagulation therapy in a teaching hospital was undertaken. The results of this audit were compared to the results of other workers who have previously emphasized controversial areas of anticoagulation therapy and potential benefits of a standard anticoagulation protocol.Charts from seventy-nine patients with a diagnosis of venous thrombosis were analyzed. Fifty-five percent of the patients were at increased risk of bleeding and forty-five percent had an extensive proximal vein thrombosis, but not apparent consideration of a heparin dose adjustment was noted. Patients received heparin for an average 9.7 days, with concomitant coumadin therapy for an average 4.8 days. Patients on heparin were over/ or undercoagulated on average 5.4 days and ninety-four percent of patients on coumadin had a PT (rabbit brain) greater than 18 seconds for at least one day. Sixty percent of patients had their dose changes noted in a tabular form for easy reference. Less than fifty percent had their hemoglobin or platelet counts followed while on heparin. The APTT and TCT are used to follow heparin therapy and discrepant results were noted in thirty-three percent. All patients' discrepancies were investigated automatically by the coagulation laboratory. Less than thirty percent of patients received formal teaching from the clinical pharmacist concerning coumadin therapy.We feel that these results show a need for a standard protocol for heparin coumadin therapy. It has been shown that a standard protocol favourable chemical, financial and therapeutic benefits

scholarly journals Knowledge and practice of quality assurance programme of X ray equipment among radiographers in Kano Metropolis

2021 ◽  
Vol 12 (2) ◽  
pp. 191-196
Author(s):  
M. Sidi ◽  
A.A. Bello
Keyword(s):  
Quality Assurance ◽  
Computed Radiography ◽  
Average Score ◽  
Quality Assurance Programme ◽  
Cross Sectional ◽  
Radiography System ◽  
Alpha Reliability ◽  
Knowledge And Practice ◽  
Ethical Clearance ◽  
Selection Of

The main goal of quality assurance programme is to consistently provide diagnostic information at the lowest possible cost, and at the least possible exposure of the patient to ionizing radiation. The study aims at evaluating the knowledge and practice of ray equipment among radiographers in Kano metropolis. The study design was prospective and cross sectional conducted among radiographers in the Kano metropolis from April 2019 to October 2019. Non-probability sampling meth used in the selection of the respondents. An ethical clearance to conduct the study was obtained from the Human Research and Ethics Committee of the Kano State Ministry of Health, and informed consent was obtained from every selected respondent. A s questionnaire was designed and used an instrument for data collection. The questionnaire was validated by experienced colleagues, using a pilot study the reliability was rested and the chronbach’s alpha reliability coefficient was found to be 0.7 one questionnaires were administered to the consented radiographers in Kano metropolis. The obtained data was analyzed using SPSS version 22.0. Out of the 41 (100%) administered questionnaires 36 (87%) were returned, and all the returned naires were properly filled. Only 3 (8.3%) known the meaning of quality assurance programme, only 12 (33.3%) know the components of quality assurance programme and only 6 (16.7%) know the frequency of computed radiography system average score for knowledge among radiographers in Kano metropolis is 44.9% and that of practice is 47.9%. The study concludes that radiographers in Kano metropolis have poor knowledge and pactice of quality assurance programme.

scholarly journals Rationale and development of an on-line quality assurance programme for colposcopy in a population-based cervical screening setting in Italy

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Lauro Bucchi ◽  
Paolo Cristiani ◽  
Silvano Costa ◽  
Patrizia Schincaglia ◽  
Paola Garutti ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Cervical Screening ◽  
Population Based ◽  
Quality Assurance Programme ◽  
On Line

THE USE OF WEB APPLICATIONS FOR THE SELECTION OF CROP GROWING TECHNOLOGIES

2018 ◽  
Vol 48 (3) ◽  
pp. 84-90 ◽  
Author(s):  
E. A. Lapchenko ◽  
S. P. Isakova ◽  
T. N. Bobrova ◽  
L. A. Kolpakova
Keyword(s):  
Web Application ◽  
Crop Production ◽  
Web Applications ◽  
Weather Forecast ◽  
Technical Institute ◽  
Software Complex ◽  
Agricultural Enterprise ◽  
Weather Situation ◽  
The Web ◽  
Selection Of

It is shown that the application of the Internet technologies is relevant in the selection of crop production technologies and the formation of a rational composition of the machine-and-tractor fl eet taking into account the conditions and production resources of a particular agricultural enterprise. The work gives a short description of the web applications, namely “ExactFarming”, “Agrivi” and “AgCommand” that provide a possibility to select technologies and technical means of soil treatment, and their functions. “ExactFarming” allows to collect and store information about temperature, precipitation and weather forecast in certain areas, keep records of information about crops and make technological maps using expert templates. “Agrivi” allows to store and provide access to weather information in the fi elds with certain crops. It has algorithms to detect and make warnings about risks related to diseases and pests, as well as provides economic calculations of crop profi tability and crop planning. “AgCommand” allows to track the position of machinery and equipment in the fi elds and provides data on the weather situation in order to plan the use of agricultural machinery in the fi elds. The web applications presented hereabove do not show relation between the technologies applied and agro-climatic features of the farm location zone. They do not take into account the phytosanitary conditions in the previous years, or the relief and contour of the fi elds while drawing up technological maps or selecting the machine-and-tractor fl eet. Siberian Physical-Technical Institute of Agrarian Problems of Siberian Federal Scientifi c Center of AgroBioTechnologies of the Russian Academy of Sciences developed a software complex PIKAT for supporting machine agrotechnologies for production of spring wheat grain at an agricultural enterprise, on the basis of which there is a plan to develop a web application that will consider all the main factors limiting the yield of cultivated crops.

scholarly journals Genomic Analysis, Progress and Future Perspectives in Dairy Cattle Selection: A Review

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 599
Author(s):  
Miguel A. Gutierrez-Reinoso ◽  
Pedro M. Aponte ◽  
Manuel Garcia-Herreros
Keyword(s):  
Dairy Cattle ◽  
Production Efficiency ◽  
Association Studies ◽  
Phenotypic Traits ◽  
Progeny Testing ◽  
Genome Wide Association Studies ◽  
Genetic Progress ◽  
Breeding Programs ◽  
Increased Risk ◽  
Selection Of

Genomics comprises a set of current and valuable technologies implemented as selection tools in dairy cattle commercial breeding programs. The intensive progeny testing for production and reproductive traits based on genomic breeding values (GEBVs) has been crucial to increasing dairy cattle productivity. The knowledge of key genes and haplotypes, including their regulation mechanisms, as markers for productivity traits, may improve the strategies on the present and future for dairy cattle selection. Genome-wide association studies (GWAS) such as quantitative trait loci (QTL), single nucleotide polymorphisms (SNPs), or single-step genomic best linear unbiased prediction (ssGBLUP) methods have already been included in global dairy programs for the estimation of marker-assisted selection-derived effects. The increase in genetic progress based on genomic predicting accuracy has also contributed to the understanding of genetic effects in dairy cattle offspring. However, the crossing within inbred-lines critically increased homozygosis with accumulated negative effects of inbreeding like a decline in reproductive performance. Thus, inaccurate-biased estimations based on empirical-conventional models of dairy production systems face an increased risk of providing suboptimal results derived from errors in the selection of candidates of high genetic merit-based just on low-heritability phenotypic traits. This extends the generation intervals and increases costs due to the significant reduction of genetic gains. The remarkable progress of genomic prediction increases the accurate selection of superior candidates. The scope of the present review is to summarize and discuss the advances and challenges of genomic tools for dairy cattle selection for optimizing breeding programs and controlling negative inbreeding depression effects on productivity and consequently, achieving economic-effective advances in food production efficiency. Particular attention is given to the potential genomic selection-derived results to facilitate precision management on modern dairy farms, including an overview of novel genome editing methodologies as perspectives toward the future.

scholarly journals The Lean Six Sigma Algorithm—A Pathway for Decreasing the Continuous Improvement Projects Failure Rate

Proceedings ◽  
2020 ◽  
Vol 63 (1) ◽  
pp. 47
Author(s):  
Karam Al-Akel ◽  
Liviu-Onoriu Marian
Keyword(s):  
Failure Rate ◽  
Continuous Improvement ◽  
Six Sigma ◽  
Lean Six Sigma ◽  
Manufacturing Processes ◽  
Timely Manner ◽  
Improvement Project ◽  
Project Failures ◽  
Specific Order ◽  
Selection Of

Even if Lean and Six Sigma tools are available for large audiences, many of the continuous improvement projects fail due to the lack of a pathway that ensures appropriate results in a timely manner. We would like to address this universal issue by generating, testing and validating an algorithm that improves manufacturing processes in a controlled manner. With a selection of the most valuable set of tools and concepts implemented in a specific order, a guideline for successful project implementation is proposed. Decreasing the overall number of continuous improvement project failures is the main scope of our algorithm and suggested methodology.

scholarly journals Examining and Fine-tuning the Selection of Glycan Compositions with GlyConnect Compozitor

2020 ◽  
Vol 19 (10) ◽  
pp. 1602-1618 ◽  
Author(s):  
Thibault Robin ◽  
Julien Mariethoz ◽  
Frédérique Lisacek
Keyword(s):  
Search Engine ◽  
Posttranslational Modifications ◽  
Search Engines ◽  
Web Application ◽  
Contextual Information ◽  
Fine Tuning ◽  
Data Sources ◽  
Web Interface ◽  
Definition Of ◽  
Selection Of

A key point in achieving accurate intact glycopeptide identification is the definition of the glycan composition file that is used to match experimental with theoretical masses by a glycoproteomics search engine. At present, these files are mainly built from searching the literature and/or querying data sources focused on posttranslational modifications. Most glycoproteomics search engines include a default composition file that is readily used when processing MS data. We introduce here a glycan composition visualizing and comparative tool associated with the GlyConnect database and called GlyConnect Compozitor. It offers a web interface through which the database can be queried to bring out contextual information relative to a set of glycan compositions. The tool takes advantage of compositions being related to one another through shared monosaccharide counts and outputs interactive graphs summarizing information searched in the database. These results provide a guide for selecting or deselecting compositions in a file in order to reflect the context of a study as closely as possible. They also confirm the consistency of a set of compositions based on the content of the GlyConnect database. As part of the tool collection of the Glycomics@ExPASy initiative, Compozitor is hosted at https://glyconnect.expasy.org/compozitor/ where it can be run as a web application. It is also directly accessible from the GlyConnect database.

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