scholarly journals Association between Glucose Levels and Intraocular Pressure: Pre- and Postprandial Analysis in Diabetic and Nondiabetic Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Luis Guilherme Milesi Pimentel ◽  
Carolina P. B. Gracitelli ◽  
Leticia Sant’Ana Cardoso da Silva ◽  
Aline Katia Siqueira Souza ◽  
Tiago Santos Prata

The aim of this study was to evaluate the relationship between glucose levels and intraocular pressure (IOP) fluctuation in diabetic and nondiabetic patients. Seventeen nondiabetic and 20 diabetic subjects underwent a complete ophthalmic examination, capillary glucose testing, and applanation tonometry in two distinct situations: first, fasting for at least 8 hours and, second, postprandial measurements. Baseline glucose levels were higher in diabetic patients (P<0.001). Postprandial IOP was significantly higher than baseline IOP in diabetic (P<0.001) and nondiabetic patients (P=0.006). Postprandial glucose levels were significantly higher than baseline measurements in both diabetic (P=0.005) and nondiabetic patients (P=0.015). There was a significant association between glucose levels variation and IOP change in both diabetic patients (R2=0.540;P<0.001) and nondiabetic individuals (R2=0.291;P=0.025). There is also a significant association between the baseline glucose levels and IOP change in diabetic group (R2=0.445;P=0.001). In a multivariable model, the magnitude of glucose level change remained significantly associated with IOP variation even including age, baseline IOP, ancestry, and gender as a confounding factor (P<0.001). We concluded that there is a significant association between blood glucose levels and IOP variation, especially in diabetic patients.

2021 ◽  
Vol 4 (1) ◽  
pp. 51-60
Author(s):  
Sunita Karki ◽  
Anjan Rai ◽  
Manish Pradhan

Introduction Acrochordons or skin tags are common benign cutaneous tumors that occur especially over the neck and major flexures. A possible association between diabetes mellitus and dyslipidemia is observed in numerous past studies with varying results. We aim to find out the association of diabetes mellitus with acrochordons Methods: One hundred patients were enrolled in our study. Among them, 50 (27 males and 23 females) with skin tags were selected as cases and 50 with other dermatologic diseases after matching age and gender were taken as controls. Blood glucose levels including both fasting and postprandial glucose levels were determined for both cases and controls and compared. Results: There was a higher frequency of Diabetes Mellitus and impaired glucose tolerance in patients with skin tags in comparison to controls (p<0.001). Moreover, there were higher odds of acquiring skin tags in patient with abnormal blood glucose levels. Conclusions: There is an increased risk of developing DM in patients with skin tags. It is highly recommended that suspicion for Diabetes Mellitus is to be done in patients with skin tags for early screening and diagnosis of Diabetes.


Author(s):  
Karim Zahed ◽  
Farzan Sasangohar ◽  
Ranjana Mehta ◽  
Madhav Erraguntla ◽  
Mark Lawley ◽  
...  

Diabetes is a prevalent condition affecting millions of patients globally. Some diabetic patients suffer from a deadly condition called Hypoglycemia (sudden drop in blood glucose levels). Continuous Glucose Monitors (CGMs) have been the most pervasive tool used to track blood glucose levels but these tools are invasive and costly. While early detection of hypoglycemia has been studied, current approaches do not leverage tremors; which are a primary symptom of hypoglycemia. A scoping review was conducted to understand the relationship between tremors and hypoglycemia, and to document any efforts that utilized tremor signatures non-invasively to detect hypoglycemic events. Findings suggest that hypoglycemic tremors are a medium frequency tremor, more resistant to hypoglycemic impairment than other symptoms, and have not been fully explored yet. This paper also documents the work in progress to utilize a novel wearable device that predicts the onsets of hypoglycemia using hand tremor sensing.


BIOEDUSCIENCE ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 120-123
Author(s):  
Putri Dafriani ◽  
Mutiara Karamika ◽  
Siska Sakti Anggraini ◽  
Roza Marlinda

Background: Diabetes Mellitus is a chronic metabolic disorder caused by insulin resistance. Noni juice has the potential as herbal medicine which believed to reduce blood glucose levels. This study aims to determine the effect of noni juice on blood sugar levels on diabetic patients. Methods: This study used 16 respondents. They divided two groups, a control group and a treatment group. Each group consists of 8 respondents. The intervention group received 150 ml of noni juice which was given once a day for ten days. Glucose testing was carried out by the glucose-check method. The blood was taken from the respondent's fingertips capillary. The blood glucose levels between the control group and the intervention group were analyzed using independent t-test. Results: The average blood glucose level in the intervention group was 199.88 mg/dl, while the control group was 326.25 mg/dl. The test results of the mean blood glucose levels between the control group and the intervention group had a significant difference with a value of p = 0.003 (p ≤ 0.05). This indicates a significant effect between blood glucose levels in the control group and the intervention group. Conclusion: Noni can reduce blood glucose levels because it contains flavonoid. It has a hypoglycemic effect. Health workers can suggest consuming noni juice to decrease blood glucose in diabetic patients.    


2017 ◽  
Vol VOLUME 5 (VOLUME 5 NUMBER 2 JULY 2017) ◽  
pp. 11-14
Author(s):  
Ankur Wats

INTRODUCTION: The Prevalence of Diabetes Melilites Is Increasing All Over the World Particularly in The Developing Countries. Diabetes Is Associated with Hearing Impairment Which Has Been Described as Sensorineural in Origin, But Evidence Favoring a Specific Mechanism Is Insufficient. Brainstem Evoked Response Audiometry Is a Simple, Non-Invasive Procedure to Detect Early Impairment of Acoustic Nerve and Auditory Pathway, Even in The Absence of Specific Symptoms. The Present Study Is Under Taken to Evaluate the Impact of Type 2 Diabetes Mellitus on BERA Parameters. OBJECTIVES: To Analyze and Compare the Brainstem Evoked Response Audiometry in Diabetic Patients and Age and Gender Matched Controls. METHODS: 40 Type 2 Diabetic Patients Attending Outpatient Department of Otorhinolaryngology and Medicine, C. S. S. Hospital, Meerut and 40 Non Diabetic Age and Gender Matched Subjects from General Population Were Selected Randomly, With None of Them Having Complains of Hearing Loss and Were Subjected to Brainstem Evoked Response Audiometry (BERA). BERA Parameters Such as Latency of Wave I, II, III, IV, And V; Inter-Peak Latencies I-III, I-V and III-V Were Analyzed. BERA Parameters Were also assessed according to The Duration of Diabetes and Fasting Blood Glucose Levels. RESULTS: Patients with Type 2 Diabetes Mellitus Were Found to Have Subclinical Hearing Impairment as Revealed by Impaired Auditory Brainstem Response. In This Study Diabetic Patients Showed a Statistically Significant (p value<0.05) Delay in The Latency of Waves I, III and V and Inter-Peak Latency of Waves I-III, I-V and III-V When Compared to Controls. There Was a Positive Correlation Between Prolongation of Latencies and Duration of Diabetes Mellitus. The Latencies Were Also Found to Be Prolonged with altered blood glucose levels. CONCLUSION: The present study correlates with earlier findings that impaired BERA response in diabetic patients is a consequence of microangiopathy. Meticulous control of blood sugar levels is a must to prevent the early complications of diabetes, so that further damage to auditory pathway can be prevented. KEY-WORDS: Diabetes mellitus; Hearing; Brainstem evoked response audiometry (BERA).


2020 ◽  
Vol 8 (1) ◽  
pp. 4
Author(s):  
Malyn Martha Lilac Ketisha Antoine ◽  
Yancheng Xu ◽  
Dodji Kossi Djakpo

The macro-vascular complications (cardiovascular, neurovascular and peripheral vascular diseases) observed in diabetic patients usually develop secondary to the presence of atherosclerotic diseases. In diabetic patients chronically elevated blood glucose levels play a major role in contributing to the development of the disease; however, in addition to hyperglycaemia, other factors such as hypertension, dyslipidaemia and obesity also contribute to the development of this condition. Despite the fact that further research is required to fully establish the relationship between hyperglycaemia and the development of atherosclerotic plaques in diabetic patients, three major pathways have already been identified for the role they play in the pathogenesis of atherosclerosis. These pathways are identified as follows: 1. non-enzymatic glycosylation of lipids and proteins 2. oxidative stress 3.Protein kinase C. This review discusses how hyperglycaemia influences the development of atherosclerosis which further leads to the development of major vascular complications in diabetic patients. 


2020 ◽  
Vol 8 (1) ◽  
pp. 24
Author(s):  
Arin Wulansari ◽  
Fryta Ameilia Luthfinnisa ◽  
Fuadah Uyun ◽  
Dwi Retnoningrum ◽  
Fifin Luthfia Rahmi ◽  
...  

Background: Obesity cause various physiological changes in the body, one of which is insulin resistance causes high blood glucose levels. Chewing is a stimulus of cephalic phase responses and sensory stimulation that can increase hormones releasing such as insulin, ghrelin, cholecystokinin (CCK) and glucagon like peptide-1 (GLP-1). Chewing plays important role in determining postprandial plasma glucose concentration.Objective: Investigate the effect of chewing on postprandial blood glucose in obese adults.Method: This was true experimental research. Research subjects were treated in the form of chewing 22 times and 40 times each mouthful. Blood glucose levels were measured using glucometer on fasting blood glucose and postprandial blood glucose 15 minutes, 30 minutes, 60 minutes, and 120 minutes. Statistical test using Independent t-test.Results: The mean postprandial glucose levels in the 22 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 112.11 ± 14.3328, 126.11 ± 15.667, 116.94 ± 15.539, and 89.67 ± 11.668 . While the mean postprandial blood glucose levels in the 40 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 122.22 ± 14.381, 129.61 ± 15.112, 109.50 ± 14.995, and 85.83 ± 13.963. There were statistically significant differences between chewing groups 22 times and chewing 40 times on fasting blood glucose and 15 minutes postprandial blood glucose (p = 0.041 and p = 0.042), while on 30 minutes postprandial glucose testing, 60 minutes , and 120 minutes there was no significant difference (p> 0.05).Conclusion: There was significant differences in 15 minutes postprandial blood glucose level between group 22 times chewing and 40 times chewing each mouthful.


1981 ◽  
Vol 15 (3) ◽  
pp. 175-179 ◽  
Author(s):  
Michael S. Torre ◽  
David H. Schofield ◽  
Robert A. Mangione ◽  
Alain Boisvert

The historical development, biosynthesis, analysis, interpretation, and utilization of glycosylated hemoglobin determinations (HbA1 or HbA1c alone) are presented. The relationship between glycosylated hemoglobin determinations and assessment of diabetic control is discussed. HbA1 and HbA1c levels are elevated approximately twofold in diabetic patients. A correlation exists between abnormal fluctuations in blood glucose levels and HbA1 concentrations. The results of glycosylated hemoglobin determinations are not influenced by recent meals, physical activity, emotional stress, or inherited abnormalities. Although glycosylated hemoglobin determinations are subject to fewer variables than blood and urine glucose assessments, the clinician must be aware of the indications and limitations for their use. These indications and limitations are discussed.


2020 ◽  
Vol 16 (4) ◽  
pp. 301-312 ◽  
Author(s):  
Jyoti Singh ◽  
Prasad Rasane ◽  
Sawinder Kaur ◽  
Vikas Kumar ◽  
Kajal Dhawan ◽  
...  

Diabetes is a globally prevalent chronic metabolic disease characterized by blood glucose levels higher than the normal levels. Sugar, a common constituent of diet, is also a major factor often responsible for elevating the glucose level in diabetic patients. However, diabetic patients are more prone to eat sweets amongst the human population. Therefore, we find a popular consumption of zero or low-calorie sweeteners, both natural and artificial. But, the uses of these sweeteners have proved to be controversial. Thus, the purpose of this review was to critically analyze and highlight the considerations needed for the development of sugar-free or low-calorie products for diabetic patients. For this purpose, various measures are taken such as avoiding sugary foods, using natural nectar, artificial sweeteners, etc. It cannot be ignored that many health hazards are associated with the overconsumption of artificial sweeteners only. These sweeteners are high-risk compounds and a properly balanced consideration needs to be given while making a diet plan for diabetic patients.


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