scholarly journals The Potential of Noni (Moringa citrifolia) in Lowering Blood Glucose Levels in Diabetes Mellitus Patients

BIOEDUSCIENCE ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 120-123
Author(s):  
Putri Dafriani ◽  
Mutiara Karamika ◽  
Siska Sakti Anggraini ◽  
Roza Marlinda

Background: Diabetes Mellitus is a chronic metabolic disorder caused by insulin resistance. Noni juice has the potential as herbal medicine which believed to reduce blood glucose levels. This study aims to determine the effect of noni juice on blood sugar levels on diabetic patients. Methods: This study used 16 respondents. They divided two groups, a control group and a treatment group. Each group consists of 8 respondents. The intervention group received 150 ml of noni juice which was given once a day for ten days. Glucose testing was carried out by the glucose-check method. The blood was taken from the respondent's fingertips capillary. The blood glucose levels between the control group and the intervention group were analyzed using independent t-test. Results: The average blood glucose level in the intervention group was 199.88 mg/dl, while the control group was 326.25 mg/dl. The test results of the mean blood glucose levels between the control group and the intervention group had a significant difference with a value of p = 0.003 (p ≤ 0.05). This indicates a significant effect between blood glucose levels in the control group and the intervention group. Conclusion: Noni can reduce blood glucose levels because it contains flavonoid. It has a hypoglycemic effect. Health workers can suggest consuming noni juice to decrease blood glucose in diabetic patients.    

2018 ◽  
Vol 3 (2) ◽  
pp. 72
Author(s):  
Setyoadi Setyoadi ◽  
Heri Kristianto ◽  
Siti Nur Afifah

Diabetes mellitus is a disease that required good self-management. Noncompliance in diet and meal plans cause the instability of blood glucose levels. Nutrition education calendar method can improve knowledge and ability to consume food that matches the number, hours and types with dietary adjustments listed in the calendar diet. This study aimed to determine the effect of nutrition education calendar method on blood glucose levels of patients with type 2 diabetes mellitus in Community Health Center Pakis Malang. Pre-experimental design one group pretest-posttest with purposive sampling was conducted in this study and sample obtained as many as 21 people. Blood glucose levels were measured before and after the nutrition education calendar methods. Compliance in using calendar method with the observation sheet. Statistical analysis values obtained by Wilcoxon, the p-value of 0.007 (p <0.05). The results of the analysis, 16 respondents showed a decrease in blood glucose levels and 5 respondents experienced an increase in blood glucose levels after the given intervention. It can be concluded that there are differences between blood glucose levels before and after nutrition education calendar method. Differences in blood glucose levels can be influenced by controlling diet respondent in accordance with the calendar method in education, but also antidiabetic drugs, and sports. Should be added to the control group to determine objectively the effect of nutrition education on the calendar method.


Author(s):  
Pipit Festi W

 Administration of oral hypoglycemic drugs and insulin is one of the most common pharmacological treatments given to people with diabetes mellitus. This treatment is carried out in the long term so that it causes side effects and is carried out continuously so that it will affect the financial condition of the diabetes mellitus patient. The purpose of this study was to determine the effect of black garlic extract on decreasing blood glucose levels in mice (mus musculus). This study uses the design of True Experimental design (pretest-posttest with control group design). The population is mice in Pusvetma Surabaya. Sampling method uses Non Probability Sampling Purposive Sampling type. Samples taken were 30 mice consisting of 15 intervention groups and 15 control groups. Data was collected using observation sheets, then analyzed using Independent sample t test and Dependent sample t test with a significance level of 5 0.05. The results showed: Using the test Independent sample T test obtained a significance value ρ = 0,000  It can be concluded that there is an effect of black onion extract to reduce blood glucose levels in mice. In the paired t-test test in the treatment group showed ρ = 0,000  that there were differences in blood glucose levels before being given extracts of garlic and after being given intervention. It is expected that black garlic can be used as an alternative medicine to reduce blood glucose levels.Keyword : Ekstrak of black garlic, Blood sugar levels, mus musculus


2017 ◽  
Vol 4 (2) ◽  
pp. 188
Author(s):  
Eryna Laili Putri

Diabetes Mellitus (DM) is a chronic disease with high prevalence, associated with various debilitating complications and can decreases the quality of life in people with it. It is important for people with DM to doing exercise to control the stability of their blood glucose levels. The purpose of this study was to finding out the association between frequency, duration, and intensity of exercise with average blood glucose levels in people with DM. This was an observational study that used case control design. Data obtained from interview with 20 samples from case group and 20 samples from control group, that had been chosen with systematic random sampling technique. Dependent variable of this study was the average blood glucose levels and independents variables were frequency, duration, intensity, and the kind of exercise. This study used Chi Square test 3 × 2 contingency tables to finding out the association and risk of dependent variable with independent variables,. The results showed that exercise factors that associated to average blood glucose levels were duration of exercise (p = 0.022) and intensity of exercise (p = 0.021). The frequency of exercise does not associated to average blood glucose levels (p = 0.340). Diabetic patients who did not do any exercise have the risk of having uncontrolled blood glucose levels. The conclusion was duration and intensity of exercise related significantly to blood glucose levels. By doing exercise three times a week for 30 minutes or more can decreases the risk of uncontrolled blood glucose levels in people with DM.Keywords: Diabetes mellitus, exercise, average blood glucose levels


2020 ◽  
Vol 6 (3) ◽  
pp. 149
Author(s):  
Indi Kamilia Fitri ◽  
Cholis Abrori ◽  
Dion Krismashogi Dharmawan

In people with diabetes mellitus (DM) there is a decrease in basal vitamin C levels which is thought to be a result of oxidative stress in the condition of hyperglycemia that it needs to increase vitamin C as an antioxidant. Hyperglycemia in DM needs to be lowered by pharmacological therapy, named glimepirid so the purpose of this study is to determine the effectiveness of vitamin C addition to the reduction of KGD hyperglycemic mice with glimepirid treatment. This study is true experimental with a sample of 25 mice 20-30 grams and divided into five groups, first the control group (K0); STZ  induction group (K1); STZ induction group with glimepirid treatment (K2); STZ induction group with the treatment of vitamin C (K3); STZ induction group by treatment of a combination of glimepirid and vitamin C (K4). STZ is injected intraperitonially 150 mg / kgBB. All groups were measured for KGD 1 after induction of STZ and KGD 2 after treatment for fourteen days. The results of the STZ induction group with the treatment of a combination of glimepirid and vitamin C (K4) experienced a smaller and not significant decrease in BSL in the STZ induction group with a single glimepirid (K2) treatment. These results are thought to have an influence from interactions between drugs that cause one drug to not work optimally. The conclusion of this study is that administration of glimepirid, vitamin C, or both can reduce blood glucose levels in hyperglycemic mice with the greatest decrease occurring in the glimepirid group.


2021 ◽  
Vol 3 (2) ◽  
pp. 285-295
Author(s):  
Umi Romayati Keswara ◽  
Rahma Elliya ◽  
Maya Maya

ABSTRACT: THE EFFECT OF PROGRESIVE MUSCLE RELAXATION (PMR) ON REDUCING BLOOD GLUCOSE LEVELS IN PEOPLE WITH DIABETES MELLITUS IN THE WORK AREA OF OGAN LIMA HEALTH CENTER, WEST ABUNG DISTRICT, NORTH LAMPUNG Introduction: Diabetes mellitus (DM) is a non-communicable disease that often suffers. Diabetes mellitus (DM) is a non-communicable disease that often suffers.Purpose: To determine the effect of progresive muscle relaxation (PMR) on reducing blood glucose levels in people with diabetes mellitus.Method: This type of research is quantitative, quasi-experimental design using non equivalent control groups. The population in this study were all DM patients in the Work Area of Ogan Lima Health Center, West Abung District, North Lampung, with a total sample of 34 respondents. Data analysis used T test analysis (dependent and independent sample t-test).Results: The results of univariate analysis showed that the average blood glucose level of respondents in the pretest group was 247.29 ± 28.431 mg / dL and posttest 210.29 ± 28.711 mg / dL. The average level of respondent's blood glucose at pretest was 255.94 ± 30.738 mg / dL and posttest 230.76 ± 25.69 mg / dL. T-dependent test results obtained by the treatment group p-value = 0,000, and the control group p-value = 0.006. T-independent test results obtained p-value = 0.035.Conclusion: There was a significant difference between the blood glucose levels of diabetics in the treatment group and the control group. Suggestions are expected that health workers can apply PMR training as an alternative therapy for DM patients. Keywords :progresive muscle relaxation, blood glucose level, diabetes mellitus  Latar Belakang: Diabetes Melitus (DM) merupakan penyakit tidak menular yang sering diderita. Data di dunia sebanyak 422 juta orang dewasa hidup dengan diabetes, di Indonesia tahun 2018 prevalensi  diabetes meningkat dari 1,1% menjadi 2,0%, di Provinsi Lampung meningkat dari 0,8% menjadi1,6%, di Kabupaten Lampung Utara meningkat dari 0,9menjadi 1,07 %. Terapi komplementer untuk mengontrol kadar glukosa darah salah satunya dengan relaksasi otot progresif (Progresive Muscle Relaxation (PMR).Tujuan:Diketahui Pengaruh Progresive Muscle Relaxation (PMR) terhadap penurunan kadar glukosa  darah pada penderita diabetes melitus.Metode Penelitian:Jenis penelitian ini adalah kuantitatif, rancangan quasi eksperiment menggunakan non equivalent control group. Populasi dalam penelitian ini adalah seluruh pasien DM di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara, dengan jumlah sampel sebanyak 34 responden.Analisis data menggunakan analisis uji T (dependent dan independent sample t-test).Hasil Penelitian: Hasil analisis univariat bahwa rata-rata kadar glukosa darah responden kelompok perlakuan saat pretest yaitu 247,29 ± 28,431 mg/dL dan posttest 210,29 ± 28,711 mg/dL. Rata-rata kadar glukosa darah responden saat pretest yaitu 255,94 ± 30,738 mg/dL dan posttest 230,76 ± 25,69mg/dL. Hasil uji t-dependen kelompok perlakuan diperoleh p-value=0,000, dan kelompok kontrol p-value=0,006. Hasil uji t-independen diperoleh p-value=0,035.Kesimpulan: Ada perbedaan yang signifikan antara kadar glukosa darah penderita diabetes melitus pada kelompok perlakuan dan kelompok kontrol. Saran diharapkan agar tenaga kesehatan dapat menerapkan latihan PMR sebagai alternative terapi pada pasien DM. Kata Kunci     : progresive muscle relaxation, kadar glukosa darah, diabetes melitus


2020 ◽  
Vol 9 (5) ◽  
pp. 314-317
Author(s):  
Tri Damayanty Syamsul ◽  
◽  
Rosdiana Natzir ◽  
Marhaen Hardjo ◽  
Hasyim Kasim ◽  
...  

Introduction Diabetes Mellitus (DM) is a multicultural metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. Abnormalities in insulin secretion or action cause problems in the metabolism of carbohydrates, fats, and proteins. DM Type II is characterized by the occurrence of insulin resistance in body tissues. Trigona honey is rich in phenolic compounds because it is food collected by bees from plants. The total phenolic content in honey is highly correlated with antioxidant activity. In this study, we aimed to see the different effects of trigona honey (Tetragonula sp) on plasma insulin and blood glucose levels in mice with diabetes mellitus. Methods. Balb/c mice (n= 28) were randomly assigned into the control group (n=7), negative control, positive control, and intervention group which received a daily intake of trigona honey (n= 14). Results. showed that administration of trigona honey can increase administration of the metformin. This is caused because honey contains high antioxidants and contains bioactive compounds such as alkaloids, flavonoids, triterpenoids, and phenol compounds. Conclusion. Daily consumption of trigona honey has a remarkable potential to decrease the blood glucose, thus it can contribute to the prevention of the diabetes mellitus development.


2017 ◽  
Vol 4 (2) ◽  
pp. 188
Author(s):  
Eryna Laili Putri

Diabetes Mellitus (DM) is a chronic disease with high prevalence, associated with various debilitating complications and can decreases the quality of life in people with it. It is important for people with DM to doing exercise to control the stability of their blood glucose levels. The purpose of this study was to finding out the association between frequency, duration, and intensity of exercise with average blood glucose levels in people with DM. This was an observational study that used case control design. Data obtained from interview with 20 samples from case group and 20 samples from control group, that had been chosen with systematic random sampling technique. Dependent variable of this study was the average blood glucose levels and independents variables were frequency, duration, intensity, and the kind of exercise. This study used Chi Square test 3 × 2 contingency tables to finding out the association and risk of dependent variable with independent variables,. The results showed that exercise factors that associated to average blood glucose levels were duration of exercise (p = 0.022) and intensity of exercise (p = 0.021). The frequency of exercise does not associated to average blood glucose levels (p = 0.340). Diabetic patients who did not do any exercise have the risk of having uncontrolled blood glucose levels. The conclusion was duration and intensity of exercise related significantly to blood glucose levels. By doing exercise three times a week for 30 minutes or more can decreases the risk of uncontrolled blood glucose levels in people with DM.Keywords: Diabetes mellitus, exercise, average blood glucose levels


2021 ◽  
Vol 3 (2) ◽  
pp. 285-295
Author(s):  
Umi Romayati Keswara ◽  
Rahma Elliya ◽  
Maya Maya

ABSTRACT: THE EFFECT OF PROGRESIVE MUSCLE RELAXATION (PMR) ON REDUCING BLOOD GLUCOSE LEVELS IN PEOPLE WITH DIABETES MELLITUS IN THE WORK AREA OF OGAN LIMA HEALTH CENTER, WEST ABUNG DISTRICT, NORTH LAMPUNG Introduction: Diabetes mellitus (DM) is a non-communicable disease that often suffers. Diabetes mellitus (DM) is a non-communicable disease that often suffers.Purpose: To determine the effect of progresive muscle relaxation (PMR) on reducing blood glucose levels in people with diabetes mellitus.Method: This type of research is quantitative, quasi-experimental design using non equivalent control groups. The population in this study were all DM patients in the Work Area of Ogan Lima Health Center, West Abung District, North Lampung, with a total sample of 34 respondents. Data analysis used T test analysis (dependent and independent sample t-test).Results: The results of univariate analysis showed that the average blood glucose level of respondents in the pretest group was 247.29 ± 28.431 mg / dL and posttest 210.29 ± 28.711 mg / dL. The average level of respondent's blood glucose at pretest was 255.94 ± 30.738 mg / dL and posttest 230.76 ± 25.69 mg / dL. T-dependent test results obtained by the treatment group p-value = 0,000, and the control group p-value = 0.006. T-independent test results obtained p-value = 0.035.Conclusion: There was a significant difference between the blood glucose levels of diabetics in the treatment group and the control group. Suggestions are expected that health workers can apply PMR training as an alternative therapy for DM patients. Keywords :progresive muscle relaxation, blood glucose level, diabetes mellitus  Latar Belakang: Diabetes Melitus (DM) merupakan penyakit tidak menular yang sering diderita. Data di dunia sebanyak 422 juta orang dewasa hidup dengan diabetes, di Indonesia tahun 2018 prevalensi  diabetes meningkat dari 1,1% menjadi 2,0%, di Provinsi Lampung meningkat dari 0,8% menjadi1,6%, di Kabupaten Lampung Utara meningkat dari 0,9menjadi 1,07 %. Terapi komplementer untuk mengontrol kadar glukosa darah salah satunya dengan relaksasi otot progresif (Progresive Muscle Relaxation (PMR).Tujuan:Diketahui Pengaruh Progresive Muscle Relaxation (PMR) terhadap penurunan kadar glukosa  darah pada penderita diabetes melitus.Metode Penelitian:Jenis penelitian ini adalah kuantitatif, rancangan quasi eksperiment menggunakan non equivalent control group. Populasi dalam penelitian ini adalah seluruh pasien DM di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara, dengan jumlah sampel sebanyak 34 responden.Analisis data menggunakan analisis uji T (dependent dan independent sample t-test).Hasil Penelitian: Hasil analisis univariat bahwa rata-rata kadar glukosa darah responden kelompok perlakuan saat pretest yaitu 247,29 ± 28,431 mg/dL dan posttest 210,29 ± 28,711 mg/dL. Rata-rata kadar glukosa darah responden saat pretest yaitu 255,94 ± 30,738 mg/dL dan posttest 230,76 ± 25,69mg/dL. Hasil uji t-dependen kelompok perlakuan diperoleh p-value=0,000, dan kelompok kontrol p-value=0,006. Hasil uji t-independen diperoleh p-value=0,035.Kesimpulan: Ada perbedaan yang signifikan antara kadar glukosa darah penderita diabetes melitus pada kelompok perlakuan dan kelompok kontrol. Saran diharapkan agar tenaga kesehatan dapat menerapkan latihan PMR sebagai alternative terapi pada pasien DM. Kata Kunci     : progresive muscle relaxation, kadar glukosa darah, diabetes melitus


2019 ◽  
Vol 1 (1) ◽  
pp. 38-50
Author(s):  
Jumari Jumari ◽  
Agung Waluyo ◽  
Wati Jumaiyah ◽  
Dhea Natashia

However limited study had examined the effect of acupressure to reduce blood glucose levels in patients with type 2 diabetes mellitus. This quasi experimental trial was conducted to identify the effect of acupressure on blood glucose level in patients with type 2 diabetes mellitus. Purposive samples of 32 patients were enrolled. They were divided into intervention (n = 16) and control group (n = 16). Paired t-test have been used to examine the effectiveness of acupressure before and after intervention. The results showed a significant difference in blood glucose levels between the intervention group and the control group (t = 4.22; p = 0.001). Acupressure is an effective intervention to reduce blood glucose levels in patients with type 2 diabetes mellitus. Acupressure can be recommended as one of the independent complementary therapies in nursing care among patient with type 2 diabetes mellitus.   Keywords: Acupressure, Blood Glucose Level, Type 2 Diabetes Mellitus.


2019 ◽  
Vol 6 (3) ◽  
pp. 786
Author(s):  
Eda Dayakar ◽  
C. Sathya Sree ◽  
E. Sanjay

Background: Diabetes mellitus is a common health problem globally. Dyslipidaemia is a major risk factor to develop cardiovascular disease in diabetics. They present study was undertaken to find out the prevalence of dyslipidaemia in type 2 diabetic patients.Methods: The present study was a cross sectional study consisting of 46 (23 male and 23 female) known type 2 diabetes mellitus patients. Age, gender, duration of diabetes, body mass index (BMI) was recorder in all the diabetic patients.  Fasting blood glucose levels, total cholesterol, triglycerides, HDL, LDL, VLDL levels were measured using standard methods and recorded.Results: The average total cholesterol, triglycerides, LDL, HDL and VLDL were 200±42mg/dl, 169.62±89.79mg/dl, 132.45±36.38mg/dl,39.1±16.6mg/dl and 35.85±17.09mg/dl respectively. The incidence of occurrence of hypercholesterolemia was 58.6% and hypertriglyceridemia 36.9%. Increased levels of LDL were observed in 30 (65.2%) patients and reduced HDL was observed in 43 (93.4%) patients. The incidence rate of dyslipidaemia was higher in female diabetic patients when compared to male diabetic patients.Conclusions: Awareness on the dyslipidaemia and its risk factors should be provided to the type 2 diabetic patients as they are more prone to get cardiovascular disease and lipid profile also should be monitored regularly along with blood glucose levels.


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