scholarly journals Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Sundar Khadka ◽  
Jeevan Bahadur Sherchand ◽  
Dinesh Binod Pokharel ◽  
Bharat Mani Pokhrel ◽  
Shyam Kumar Mishra ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Trichophyton Mentagrophytes ◽  
Clinical Findings ◽  
University Teaching ◽  
Care Hospital ◽  
Fungal Treatment ◽  
Superficial Mycoses ◽  
Superficial Mycosis

Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as well as mycological profile of superficial mycoses in a tertiary care hospital, Nepal.Methods. This was a prospective case-control laboratory based study conducted over a period of six months from January to June 2014 at Tribhuvan University Teaching Hospital, Nepal. A total of 200 specimens were collected from the patients suspected of superficial mycoses. The specimens were macroscopically as well as microscopically examined. The growth was observed up to 4 weeks.Results.Out of total 200 specimens from the patients suspected of superficial mycoses, tinea corporis 50 (25%) was most common clinical types. KOH mount was positive in 89 (44.5%) and culture was positive in 111 (55.5%).Trichophyton mentagrophytes44 (39.6%) was the most common isolate.Conclusions.The diagnostic yields of KOH mount and culture were found to be complementary to each other. Thus both the methods added with clinical findings are equally important to establish superficial mycosis.

A study on the antifungal susceptibility pattern of dermatophytes isolated in a tertiary care hospital

2017 ◽  
Vol 6 (05) ◽  
pp. 5379
Author(s):  
Vanathi Sabtharishi* ◽  
Radhika Katragadda ◽  
Thyagarajan Ravinder
Keyword(s):  
Tertiary Care Hospital ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Antifungal Drugs ◽  
Dilution Method ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Superficial Mycosis ◽  
Broth Dilution ◽  
Common Infections

Recent years, due to increased usage of antifungal treatment worldwide, there is an increased chance of rising resistance among antifungal drugs too. Dermatophytic infections causes’ superficial mycosis and it affects skin, hair and nail. These infections are more common and antifungal drugs are used everywhere to treat those common infections. To conduct a study by determining the antifungal susceptibility pattern in dermatophytic isolates from patients attending dermatology OPD in a tertiary care hospital. A total of 217 samples like hair, nail and skin scrapings were obtained and isolation of dermatophytes was done. Antifungal susceptibility testing for dermatophytes was performed by micro broth dilution method. Antifungal drugs tested were Griseofulvin, Fluconazole, Itraconazole and Ketoconazole. Minimum inhibitory concentration for each drug for fungal isolates was tested and results studied. Fluconazole showed a higher MIC values in the range of 1-8µg/ml. Itraconazole showed the lowest MIC values by micro broth dilution method. Since there is limitation of standard guidelines and protocol, meticulous research must be conducted on effect of antifungals and derive at universally implementable guidelines.

Characterization of particulate matter 2.5 in an urban tertiary care hospital in the Philippines

2015 ◽  
Vol 92 ◽  
pp. 432-439 ◽  
Author(s):  
Marian Fe Theresa C. Lomboy ◽  
Leni L. Quirit ◽  
Victorio B. Molina ◽  
Godofreda V. Dalmacion ◽  
Joel D. Schwartz ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
The Philippines ◽  
Care Hospital ◽  
Particulate Matter 2.5

scholarly journals Patterns and Causality Assessment of Adverse Drug Reactions in Inpatients of a Tertiary Care Hospital, Nepal

2020 ◽  
Vol 42 (3) ◽  
pp. 97-101
Author(s):  
Anish Mudvari ◽  
Dipendra Yadav ◽  
Rakesh Ghimire ◽  
Pravin Prasad
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Exposure ◽  
Causality Assessment ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
University Teaching ◽  
Care Hospital ◽  
Drug Reactions ◽  
Clinical Events ◽  
The World

Introduction Adverse drug reaction (ADR) is a leading cause of morbidity and mortality around the world. Causality assessment is done to establish relation of drug exposure with undesired clinical events. This study conducted in tertiary care hospital was undertaken to evaluate the patterns of ADR and causality assessment using Naranjo causality algorithm. MethodsData on suspected ADR cases were collected retrospectively from Medicine and Dermatology wards of Tribhuvan University Teaching Hospital, Kathmandu from April 2018 to April 2019. Naranjo causality assessment was performed. Statistical analysis was done using SPSS version 18. ResultsOf 34 suspected ADR, occurrence of ADR was more in females (18) as compared to males (16). Skin and integumentary system was the most common organ affected (35.29%). Pyrazinamide induced hepatitis was found to be the most common suspected ADR. Causality assessment was performed and ADRs were categorized as possible 17 (50%), probable 16 (47.06%) and definite 1 (2.94%). ConclusionThe patients are commonly admitted at the hospital due to suspected ADRs. Pyrazinamide induced hepatitis was the most common suspected ADR.

scholarly journals Characterization of Patients with Thymic Tumors in a Tertiary Care Hospital in Latin America

2020 ◽  
Author(s):  
L. Fernandez ◽  
E.I. Morales ◽  
D.F. Scarpetta ◽  
V. Zuniga ◽  
D. Martinez ◽  
...  
Keyword(s):  
Latin America ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Thymic Tumors
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