Antibacterial Activity of Partially Oxidized Ag/Au Nanoparticles against the Oral PathogenPorphyromonas gingivalisW83

Advances in nanotechnology provide opportunities for the prevention and treatment of periodontal disease. While physicochemical properties of Ag containing nanoparticles (NPs) are known to influence the magnitude of their toxicity, it is thought that nanosilver can be made less toxic to eukaryotes by passivation of the NPs with a benign metal. Moreover, the addition of other noble metals to silver nanoparticles, in the alloy formulation, is known to alter the silver dissolution behavior. Thus, we synthesized glutathione capped Ag/Au alloy bimetallic nanoparticles (NPs)viathe galvanic replacement reaction between maltose coated Ag NPs and chloroauric acid (HAuCl4) in 5% aqueous triblock F127 copolymer solution. We then compared the antibacterial activity of the Ag/Au NPs to pure Ag NPs onPorphyromonas gingivalisW83, a key pathogen in the development of periodontal disease. Only partially oxidized glutathione capped Ag and Ag/Au (Au : Ag ≈ 0.2) NPs inhibited the planktonic growth ofP. gingivalisW83. This effect was enhanced in the presence of hydrogen peroxide, which simulates the oxidative stress environment in the periodontal pocket during chronic inflammation.

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Antibacterial activity of royal jelly-mediated green synthesized silver nanoparticles

AMB Express ◽

10.1186/s13568-021-01213-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Susanna Gevorgyan ◽

Robin Schubert ◽

Mkrtich Yeranosyan ◽

Lilit Gabrielyan ◽

Armen Trchounian ◽

...

Keyword(s):

Silver Nanoparticles ◽

Antibacterial Activity ◽

Green Synthesis ◽

Royal Jelly ◽

Fluorescence Emission ◽

Spherical Particles ◽

Ag Nps ◽

Gram Negative ◽

Green Synthesized Silver Nanoparticles ◽

Higher Sensitivity

AbstractThe application of green synthesis in nanotechnology is growing day by day. It’s a safe and eco-friendly alternative to conventional methods. The current research aimed to study raw royal jelly’s potential in the green synthesis of silver nanoparticles and their antibacterial activity. Royal jelly served as a reducing and oxidizing agent in the green synthesis technology of colloidal silver nanoparticles. The UV–Vis maximum absorption at ~ 430 nm and fluorescence emission peaks at ~ 487 nm confirmed the presence of Ag NPs. Morphology and structural properties of Ag NPs and the effect of ultrasound studies revealed: (i) the formation of polydispersed and spherical particles with different sizes; (ii) size reduction and homogeneity increase by ultrasound treatment. Antibacterial activity of different concentrations of green synthesized Ag NPs has been assessed on Gram-negative S. typhimurium and Gram-positive S. aureus, revealing higher sensitivity on Gram-negative bacteria.

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Bimetallic Nanoparticles Associating Noble Metals and First-Row Transition Metals in Catalysis

ACS Nano ◽

10.1021/acsnano.0c09744 ◽

2021 ◽

Author(s):

Irene Mustieles Marin ◽

Juan M. Asensio ◽

Bruno Chaudret

Keyword(s):

Transition Metals ◽

Noble Metals ◽

Bimetallic Nanoparticles

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Influence of monometallic and bimetallic phytonanoparticles on physiological status of mezquite

Open Life Sciences ◽

10.1515/biol-2019-0008 ◽

2019 ◽

Vol 14 (1) ◽

pp. 62-68 ◽

Cited By ~ 3

Author(s):

Daniel Gonzalez-Mendoza ◽

Benjamín Valdez-Salas ◽

Erick Bernardo-Mazariegos ◽

Olivia Tzintzun-Camacho ◽

Federico Gutiérrez-Miceli ◽

...

Keyword(s):

Bimetallic Nanoparticles ◽

Positive Impact ◽

Photochemical Efficiency ◽

Localized Surface Plasmon ◽

Physiological Status ◽

Ag Nps ◽

Zeta Potentials ◽

Minimum Particle Size ◽

Ag Particles ◽

The Impact

AbstractThe present study was conducted to evaluate the impact of monometallic and bimetallic nanoparticles (NPs) of copper (Cu) and silver (Ag) from Justicia spicigera on the photochemical efficiency and phenol pattern of Prosopis glandulosa. In this study, the existence of localized surface plasmon resonance absorption associated with the nano-sized nature of Ag, Cu and Cu/Ag particles was confirmed by the presence of a single peak around 487, 585, and 487/580 nm respectively. Zeta potential and electrophoretic mobility were found to be 0.2 mV and 0.02 μmcm/(Vs) for synthesized NPs indicating less stability and thus tendency to agglomerate, and broad distribution of particles. Cu-NPs and Cu/Ag-NPs demonstrate that the dispersed phase is stable and has a minimum particle size at zeta potentials above –30 mV. Changes in phenolic compounds, total chlorophyll, and photochemical efficiency in leaves exposed to Ag, Cu and Cu/Ag phyto-nanoparticles were evaluated up to 72 hours. The results revealed that Ag-NP and Cu-NP from J. spicigera at 100 mg/L showed significant reduction in chlorophyll, epidermal polyphenol content and photochemical efficiency of P. glandulosa. In contrast, the application of bimetallic Cu/Ag-NP from J. spicigera showed a positive impact on physiological parameters of P. glandulosa after 72 h of exposure.

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Relationship Between Body Mass Index and Chronic Periodontitis

Journal of Nepalese Society of Periodontology and Oral Implantology ◽

10.3126/jnspoi.v5i1.38176 ◽

2021 ◽

Vol 5 (1) ◽

pp. 7-10

Author(s):

Shreeya Aryal ◽

Ameena Pradhan ◽

Shilu Shrestha ◽

Surendra Man Shrestha

Keyword(s):

Body Mass Index ◽

Periodontal Disease ◽

Body Mass ◽

Disease Status ◽

Periodontal Pocket ◽

Potential Threat ◽

Predisposing Factor ◽

Clinical Attachment Loss ◽

Cross Sectional ◽

Attachment Loss

Introduction: Obesity is regarded as unnecessary body fat in ratio to lean body mass. Besides being an established risk factor for cardiovascular and other systemic diseases, obesity has been suggested to be a potential threat for periodontitis as well. Objective: The objective of the study was to learn relationship between body mass index (BMI) and periodontal disease. Methods: This analytical cross-sectional study was conducted at People’s Dental College from February 16 to April 15, 2021 after ethical approval. Seventy-two participants were selected conveniently who, on the basis of calculation of weight and height were allocated into two groups: Group A: participants with normal BMI, Group B: Obese/ overweight individuals. Plaque index, gingival index, periodontal pocket, and clinical attachment loss were recorded in both the groups to assess the periodontal disease status. On basis of findings, the two groups were statistically compared. Results: The result showed clinical attachment loss was significantly higher (P <0.001) in overweight/obese group than in normal BMI group (P =0 .001). Conclusion: The findings of this study suggest that obesity and overweight can be a possible predisposing factor for periodontal disease.

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Excellent fabrication of Pd-Ag NPs/PSi photocatalyst based on bimetallic nanoparticles for improving methylene blue photocatalytic degradation

Optik ◽

10.1016/j.ijleo.2018.11.011 ◽

2019 ◽

Vol 179 ◽

pp. 708-717 ◽

Cited By ~ 13

Author(s):

Layla A. Wali ◽

Alwan M. Alwan ◽

Amer B. Dheyab ◽

Duaa A. Hashim

Keyword(s):

Methylene Blue ◽

Photocatalytic Degradation ◽

Bimetallic Nanoparticles ◽

Ag Nps

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“Green” Synthesis of Metallic Nanoparticles by Sonoelectrochemical and Sonogalvanic Replacement Methods

Bioinorganic Chemistry and Applications ◽

10.1155/2021/9830644 ◽

2021 ◽

Vol 2021 ◽

pp. 1-17

Author(s):

Оrest Kuntyi ◽

Galyna Zozulya ◽

Andriy Kytsya

Keyword(s):

Green Synthesis ◽

Electrochemical Reduction ◽

Metallic Nanoparticles ◽

Bimetallic Nanoparticles ◽

Galvanic Replacement ◽

Pulsed Ultrasound ◽

Environmental Friendliness ◽

And Shock Waves ◽

Sonoelectrochemical Synthesis

The main features of the “green” synthesis of metallic nanoparticles (MNPs) by the sonoelectrochemical methods are manufacturability, environmental friendliness, and the possibility of controlling the geometry of the forming particles. The electrochemical reduction technique allows efficiently designing the metal nanoparticles and provides the control of the content of components of bimetallic nanoparticles, as well as minimizing the number of precursors in working solutions. Due to the generation of turbulence, microjets, and shock waves, ultrasound increases mass transfer and formation of radicals in aqueous solutions and, accordingly, accelerates the processes of nucleation and growth of MNPs. Therefore, this hybrid method, which combines electrolysis and ultrasound, has attracted the interest of researchers in the last two decades as one of the most promising techniques. The present work presents a short analysis of the reference literature on sonoelectrochemical synthesis of metallic and bimetallic nanoparticles. The main factors influencing the geometry of nanoparticles and their size distribution are analyzed. The use of pulsed ultrasound and pulsed current supply during sonoelectrochemical synthesis is especially effective in designing MNPs. Emphasis is placed on the role of surfactants in the formation of MNPs and sacrificial anodes in providing the algorithm: “anodic dissolution-electrochemical reduction of metal-nucleation and formation of МNPs.” It is noted that ultrasound allows synthesizing the MNPs and M1M2NPs during the galvanic replacement, and an analogy of the formation of nanoparticles by sonogalvanic replacement and sonoelectrochemical method is shown.

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The Effect of Periodontal Pocket Irrigation Using Cetylpyridinium Chloride (CPC) on Clinical Signs and Oral Bacterial Flora in Patients with Periodontal Disease.

Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) ◽

10.2329/perio.33.448 ◽

1991 ◽

Vol 33 (2) ◽

pp. 448-457 ◽

Cited By ~ 1

Author(s):

Naoya IWASAKI ◽

Hiroshi ITO ◽

Yoshinari HARA ◽

Tohru MUSHIAKE ◽

Hiroyuki KONOBU ◽

...

Keyword(s):

Periodontal Disease ◽

Cetylpyridinium Chloride ◽

Bacterial Flora ◽

Clinical Signs ◽

Periodontal Pocket

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Periodontal clinical features of bronchial asthma patient using inhalation drugs

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol33no3.29739 ◽

2021 ◽

Vol 33 (3) ◽

pp. 217

Author(s):

Maria Efrinta Ginting ◽

Rosiliwati Wihardja ◽

Dyah Nindita Carolina

Keyword(s):

Periodontal Disease ◽

Clinical Features ◽

Bronchial Asthma ◽

Periodontal Pocket ◽

Periodontal Status ◽

Asthmatic Patients ◽

Gingival Bleeding ◽

Periodontal Index ◽

Asthma Patients ◽

One Year

Introduction: Bronchial asthma patients use inhalation drugs as therapy to achieve a controlled asthma state. Inhaled corticosteroids and β2 agonists are the medication that is being used in this case. Prolonged use of inhalation drugs will affect the health of periodontal tissue. The effect of these drugs can reduce the periodontal defense mechanism and increase the risk of periodontal disease. This study aims to determine the periodontal clinical features of bronchial asthma patients using inhalation drugs. Method: This research was a descriptive study. The sample of the study were 22 females and 8 males bronchial asthma patients at the Community Lung Health Center of Bandung (Balai Besar Kesehatan Paru Masyarakat Bandung/BBKPM Bandung) who had been using inhalation drugs for at least one year. The periodontal clinical feature was assessed by employing a Community Periodontal Index (CPI) modified with probing the gingival sulcus to assess the presence of gingival bleeding, periodontal pocket, and loss of clinical attachment where then a periodontal status was obtained. The periodontal status data were then processed using the periodontitis case definitions from the Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) to determine periodontal disease in asthmatics patients. Results: Clinical features of gingival bleeding were found in 26 asthmatic patients (86.7%), periodontal pockets in 18 asthmatic patients (60%), and loss of clinical attachment in 27 asthmatic patients (90%). Based on the CDC/AAP case definition, 23 asthmatic patients (76.7%) had periodontitis. Bronchial asthma patients who used inhalation drugs had a risk of periodontitis.Conclusion: Bronchial asthma patients who used inhalation drugs for at least one year had gingival bleeding and loss of clinical attachment and periodontal pocket.

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Detection of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans strains in patients with periodontal disease

Pesquisa Odontológica Brasileira ◽

10.1590/s1517-74912003000200016 ◽

2003 ◽

Vol 17 (2) ◽

pp. 183-188 ◽

Cited By ~ 12

Author(s):

Sheila Cavalca Cortelli ◽

Antonio Olavo Cardoso Jorge ◽

José Roberto Cortelli ◽

Shawn Francis Jordan ◽

Violet Ibyola Haraszthy

Keyword(s):

Periodontal Disease ◽

Strong Association ◽

Aggressive Periodontitis ◽

Actinobacillus Actinomycetemcomitans ◽

Periodontal Pocket ◽

Chain Reaction ◽

Chi Square ◽

Pocket Depth ◽

Polymerase Chain ◽

Brazilian Cohort

This study examined the prevalence of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans in patients with periodontal disease. Pooled subgingival plaque samples from 136 patients with some form of periodontal disease were examined. Subjects were between 14 and 76 years of age. Clinical examinations included periodontal pocket depth (PD), plaque index (PI) and bleeding index (BI). The obtained plaque samples were examined for the presence of highly or minimally leukotoxic A. actinomycetemcomitans strains by the polymerase chain reaction (PCR). Chi-square and logistic regression were performed to evaluate the results. Forty-seven subjects were diagnosed with gingivitis, 70 with chronic periodontitis and 19 with aggressive periodontitis. According to chi-square there was no significant correlation detected between PD (chi2 = 0.73), PI (chi2 = 0.35), BI (chi2 = 0.09) and the presence of the highly leukotoxic A. actinomycetemcomitans. The highly leukotoxic A. actinomycetemcomitans strains were correlated with subjects that were 28 years of age and younger (chi2 = 7.41). There was a significant correlation between highly leukotoxic A. actinomycetemcomitans and aggressive periodontitis (chi2 = 22.06). This study of a Brazilian cohort confirms the strong association between highly leukotoxic A. actinomycetemcomitans strains and the presence of aggressive periodontitis.

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