scholarly journals A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Shih-Feng Chou ◽  
Simi Gunaseelan ◽  
Mhd Hussam Hijazi Kiellani ◽  
Venkata Vamsi Krishna Thottempudi ◽  
Pierre Neuenschwander ◽  
...  

The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing.

2019 ◽  
Vol 7 (7) ◽  
pp. 2652-2674 ◽  
Author(s):  
Susheel Kumar Nethi ◽  
Sourav Das ◽  
Chitta Ranjan Patra ◽  
Sudip Mukherjee

The emergence of inorganic nanoparticles has generated considerable expectation for solving various biomedical issues including wound healing and tissue regeneration. This review article highlights the role and recent advancements of inorganic nanoparticles for wound healing and tissue regeneration along with their advantages, clinical status, challenges and future directions.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 308
Author(s):  
Sandra Ruiz-Alonso ◽  
Ilia Villate-Beitia ◽  
Idoia Gallego ◽  
Markel Lafuente-Merchan ◽  
Gustavo Puras ◽  
...  

Three-dimensional (3D) printing is a game changer technology that holds great promise for a wide variety of biomedical applications, including ophthalmology. Through this emerging technique, specific eye tissues can be custom-fabricated in a flexible and automated way, incorporating different cell types and biomaterials in precise anatomical 3D geometries. However, and despite the great progress and possibilities generated in recent years, there are still challenges to overcome that jeopardize its clinical application in regular practice. The main goal of this review is to provide an in-depth understanding of the current status and implementation of 3D bioprinting technology in the ophthalmology field in order to manufacture relevant tissues such as cornea, retina and conjunctiva. Special attention is paid to the description of the most commonly employed bioprinting methods, and the most relevant eye tissue engineering studies performed by 3D bioprinting technology at preclinical level. In addition, other relevant issues related to use of 3D bioprinting for ocular drug delivery, as well as both ethical and regulatory aspects, are analyzed. Through this review, we aim to raise awareness among the research community and report recent advances and future directions in order to apply this advanced therapy in the eye tissue regeneration field.


2021 ◽  
Vol 8 ◽  
Author(s):  
Ruixuan Wang ◽  
Hongli Mou ◽  
Xiaozhi Lin ◽  
Hui Zhu ◽  
Bing Li ◽  
...  

Plastic fragments < 5 mm, known as microplastics (MPs), are ubiquitously present in the marine environment. Research on MPs pollution has gradually shifted from field investigations to laboratory studies. With the rapid growth of plastic consumption and the prevalence of aquaculture products, studies on marine MPs have focused on key marine species, such as mollusks. This review summarizes the recent knowledge including 77 important relevant literatures (from 2010 to 2021) on MPs contamination in mollusks with the objectives of (1) elucidating the current status of MPs pollution levels in mollusks, (2) highlighting the main methods and techniques for separation, extraction, and identification of MPs in soft tissues of bivalves and (3) presenting the current research progress and future directions. The review visually presents some of the important results in graphic form, which shows that the most common polymer plastics in bivalves are polypropylene, polystyrene, and polyethylene, and the shapes were mainly fiber and threadiness, mollusks are more likely to feed smaller MPs, most of the MPs in bivalves are less than 500 μm, and the abundance of MPs in seawater and the abundance of MPs in mollusks have a positive relationship, etc. This review will provide a comprehensive reference for studies of microplastics in marine organisms and the ecological pollution, and also has scientific guiding significance in the research method.


Author(s):  
Shaikh Md Mominul Alam ◽  
Shilpi Akter ◽  
Md Lutfor Rahman

The aim of this paper is to introduce novel dressing with Mikania Micrantha for quick blood clotting and wound healing. When epidermis of human skin is cut or scrapped, sometimes too much bleeding occurs. Excessive bleeding may cause death, if bleeding is not stopped immediately. To promote blood clotting & wound healing natural based bio materials are still insufficient in medical textile sector. To fill up this scarcity, woven fabric treated with Mikania micrantha leaf juice & leaf powder was examined. M. micrantha exhibits good blood clotting time in comparison with available dressing materials. Woven fabric (bandage) that contains M. micrantha can be used for cut wounds healing purpose. The experiments were carried out in environment friendly way which indicates the production & processing of these dressing materials can have enormous contribution to sustainable operations and products.


1997 ◽  
Vol 3 (1) ◽  
pp. 233-239 ◽  
Author(s):  
Patrick Holmes

The international dimension of science and engineering education is of paramount importance and merits serious consideration of the coherent skill set that is required to allow scientists and engineers more readily to transport themselves and their work to other locations in the world. 


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