scholarly journals Glomangioma of the Kidney: A Rare Case of Glomus Tumor and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Ammar Almaghrabi ◽  
Nizar Almaghrabi ◽  
Haneen Al-Maghrabi
Keyword(s):  
Glomus Tumor ◽  
Histopathological Analysis ◽  
Kidney Tumors ◽  
Mesenchymal Tumors ◽  
Unique Case ◽  
Glomus Tumors ◽  
Extensive Search ◽  
One Year ◽  
Immunohistochemical Studies ◽  
Histopathology Examination

Background. Glomus tumors are rare mesenchymal tumors originating from glomus bodies in the skin. Glomus tumors of the kidney are rare tumors and only a few cases have been reported in the medical literature. An extensive search revealed a very limited number of primary renal glomus tumors. Although most of these cases were benign in nature, including a case with uncertain diagnosis of malignant potential, two were malignant. Case Report. We present a unique case of a 57-year-old male patient with an incidentally discovered 2 cm left renal mass. Histopathology examination and immunohistochemical studies confirm the diagnosis of glomangioma (a form of glomus tumor). The patient was followed for one year after partial nephrectomy and showed a benign course without any evidence of local recurrence or metastasis. Conclusion. To the best of our knowledge, this is the 16th case of primary benign renal glomus tumors. Primary renal glomus tumors are rare and may mimic other mesenchymal renal neoplasms radiologically. Proper investigation (including histopathological analysis and immunohistochemical staining) of kidney tumors is essential to make the diagnosis of glomus tumors, which usually show a benign clinical course following resection.

scholarly journals Primary pancreatic glomus tumor invading into the superior mesenteric vein: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Ichiro Tamaki ◽  
Yohei Hosoda ◽  
Hironobu Sasano ◽  
Yu Sasaki ◽  
Hidenori Kiyochi ◽  
...  
Keyword(s):  
Case Report ◽  
Tumor Cells ◽  
Solid Tumor ◽  
Superior Mesenteric Vein ◽  
Glomus Tumor ◽  
Small Cells ◽  
Histopathological Analysis ◽  
Glomus Tumors ◽  
Mesenteric Vein ◽  
Direct Invasion

Abstract Background Glomus tumors are subcutaneous tumors arising from glomus bodies, thermoregulatory components of the skin. These tumors could occur in visceral organs where glomus bodies are not normally present. Herein, we report a case of primary pancreatic glomus tumor with aggressive direct invasion into the superior mesenteric vein (SMV). To the best of our knowledge, this is the second case report of a glomus tumor arising in the pancreas. Case presentation A 46-year-old woman was referred to our hospital due to vomiting with epigastric and back pain. Dynamic-CT revealed a well-circumscribed hypervascular mass, measuring 37 mm in its maximal diameter involving the pancreatic head. Both CT and endoscopic ultrasonography (EUS) revealed direct invasion into the SMV and radiologically suspected tumor thrombus. Biopsy sample obtained by EUS-guided fine needle aspiration revealed proliferation of small cells, round-to-oval tumor cells with round nuclei and scant cytoplasm. A histological diagnosis of pancreatic neuroendocrine tumor, G1 was initially considered. Therefore, subtotal stomach-preserving pancreatoduodenectomy using Child-II reconstruction was subsequently performed. Her SMV was resected and reconstructed due to extensive tumor involvement. Subsequent histopathological analysis revealed solid tumor cells proliferation that comprised oval-shaped nuclei and scant cytoplasm around disorganized or slit-shaped vessels in hematoxylin–eosin-stained slides. Immunohistochemical analysis then demonstrated positive immunoreactivity for smooth muscle actin, vimentin, and CD34, but negative for chromogranin A, synaptophysin, CD56, and signal transducer and activator of transcription 6. Based on these histological findings of resected specimens, the lesion was subsequently diagnosed as a primary pancreatic glomus tumor harboring direct invasion into the SMV. Her postoperative course was uneventful and annual surveys for the following 4 years post-op detected no clinical signs of recurrence. Conclusions We report a very rare case of glomus tumor of the pancreas accompanied by venous invasion. Curative surgical resection is the best treatment option for pancreatic glomus tumors. Although pancreatic glomus tumor is rare, it should be taken into consideration in the differential diagnosis of a pancreatic solid tumor with hypervascularity.

Pediatric Malignant Glomus Tumor of the Cervical Paraspinal Tissue: Case Report and Review of the Literature

2020 ◽  
Author(s):  
Andrea Ziegler ◽  
Eric Thorpe
Keyword(s):  
Glomus Tumor ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
The Body ◽  
Long Term Outcomes ◽  
Mesenchymal Tumors ◽  
En Bloc ◽  
Glomus Tumors ◽  
First Case

AbstractGlomus tumors are mesenchymal tumors that arise from glomus bodies and most frequently occur in the distal extremities. These tumors can occur throughout the body and are typically benign. However, a very small fraction of glomus tumors displays aggressive features and are considered atypical or malignant. We report on our experience and management of the first case in the literature of a malignant glomus tumor in a child originating in the paraspinal region with involvement of the cervical spine. Malignant glomus tumors tend to be locally aggressive, and en bloc resection is difficult, especially when the tumors occur in the head and neck. Additional studies on disease progression and adjuvant treatment outcomes are necessary to determine the best treatment approach and long-term outcomes in patients with malignant glomus tumors.

scholarly journals Angioleiomyoma of the Tongue- A Rare Peculiar Entity

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Garima Rawat
Keyword(s):  
Oral Cavity ◽  
Who Classification ◽  
Spindle Cell ◽  
Soft Tissue Tumors ◽  
Histopathological Analysis ◽  
Mesenchymal Tumors ◽  
Lateral Border ◽  
Immunohistochemical Studies ◽  
Slow Growing ◽  
Who Classification 2016

Angioleiomyomas (ALs) are benign mesenchymal tumors which were considered to be of smooth muscle origin, until the latest WHO classification (2016) of soft tissue tumors, in which it was reclassified as a tumor of perivascular origin. The majority of ALs occurs in the uterus, gastrointestinal tract and skin; AL of the oral cavity is infrequent, and AL of the tongue is particularly rare. These usually appear as solitary, slow-growing masses and are seldom observed in oral cavity. Here, we present a case of a fifty four year old male with a lesion on the left lateral border of the tongue, clinically mimicking a neurofibroma/ schwannoma. In this article we highlight the importance of scrupulous and detailed histopathological analysis and differential immunohistochemical studies which are essential for the diagnosis of AL from other spindle cell lesions.

scholarly journals Gastric Glomus Tumor: A Clinicopathologic and Immunohistochemical Study of 21 Cases

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Jun Lin ◽  
Juan Shen ◽  
Hao Yue ◽  
Qiongqiong Li ◽  
Yuqing Cheng ◽  
...  
Keyword(s):  
Glomus Tumor ◽  
Smooth Muscle Actin ◽  
Treatment Method ◽  
Clinical Findings ◽  
Mesenchymal Tumors ◽  
Glomus Tumors ◽  
Common Location ◽  
Local Surgery ◽  
Nest Pattern ◽  
The Mean

Gastric glomus tumors (GGTs) are rare mesenchymal tumors. Most glomus tumors occur in the distal parts of the extremities. Here, we retrospectively analyzed the features of GGTs from two institutions. The histologic and clinical findings of all GGT cases from 2009 to 2018 were reviewed. The most common location was the antrum, the mean age of patients was 49.3 years, and the mean tumor size was 2.1 cm. Microscopically, small, round cell nodules surrounded the expansion of blood vessels in a nest pattern. Immunohistochemical assays for vimentin and smooth muscle actin (SMA) were positive, and assays for H-caldesmon and calponin were partially positive. GGT is rare and easily misdiagnosed before operation. However, immunohistochemistry is useful for the differential diagnosis. The majority of GGTs are benign, and local surgery achieving complete resection is the most effective treatment method.

CT and MRI imaging of glomus tumors of the temporal bone

2018 ◽  
pp. 26-32
Author(s):  
E. A. Stepanova ◽  
М. V. Vishnyakova ◽  
V. I. Sambulov ◽  
I. Т. Mukhamedov
Keyword(s):  
Magnetic Resonance ◽  
Diagnostic Imaging ◽  
Temporal Bone ◽  
Glomus Tumor ◽  
Magnetic Resonance Tomography ◽  
Mri Imaging ◽  
Glomus Tumors ◽  
Magnetic Resonance Imaging Mri ◽  
Temporal Bone Tumor ◽  
Ct And Mri

Glomus tumor is one of the most common temporal bone tumors. Most of them are benign and locally invasive, some are occasionally able to metastasize and have signs of malignancy. Diagnostic imaging is necessary before treatment. Computer tomography (CT) is traditionally used as a primary method of diagnosis, to recognize changes in the temporal bone. Role of magnetic resonance imaging (MRI) in temporal bone tumor diagnosis is not definitively determined.Purpose. To assess the possibilities of computer and magnetic resonance tomography, to develop an algorithm for the application of diagnostic imaging methods in the diagnosis of glomus tumors of the temporal bone.Material and methods. The article presents the experience of diagnosing 30 patients with glomus tumors.Results. The tympanic form of the glomus tumor was observed in 11 cases (37%), tympano-yugular in 19 cases (63%). CT and MRI data totally coincided in cases of small tumors (type A and B). In the presence of extended forms CT ability of assessing bone invasion, involvement of the internal carotid artery, internal jugular vein, and dural sinuses was lower than the MRI.

scholarly journals Digital Glomus Tumor: Bibliographic Review of the Studies Published over the Past 10 Years

2021 ◽  
Vol 49 (01) ◽  
pp. 046-055
Author(s):  
Victoria Hernández ◽  
Tania Lena ◽  
Eliana Camacho ◽  
Matías Craviotto
Keyword(s):  
Glomus Tumor ◽  
Case Reports ◽  
Low Frequency ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Glomus Tumors ◽  
The Past ◽  
Pubmed Search ◽  
Magnetic Resonance Imaging Mri

AbstractGlomus tumors are a mostly benign neoplasm that constitutes less than 4% of upper-limb soft-tissue tumors. Its unspecific clinical presentation, added to its low frequency, leads to a late diagnosis.The objective of the present study is to update the clinical-paraclinical approach and the surgical technique used in the treatment.We carried out a literature review from 2014 to 2019 on digital glomus tumor in the hand in adult patients using the PubMed search engine.In most of the publications analyzed, the diagnosis was clinical, with a delay of 1 to 10 years. Plain radiography is the most requested study; of the 16 articles reporting its indication, only half evidenced compatible changes. Magnetic resonance imaging (MRI) was requested in 15 articles, presenting normal results in 3 of them. The treatment of choice was surgical excision using a transungual approach. Only 4 articles report recurrence after excision.Although there is diversity in the approach to these tumors, we conclude that the diagnosis is clinical, and the treatment surgical, and there is no consensus regarding the paraclinical indication. The information available comes mainly from case reports, publications that contribute to the generation of evidence for the clinical practice in rare diseases such as this one.

scholarly journals Intravascular Glomus Tumor of the Forearm Causing Chronic Pain and Focal Tenderness

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Sang Ki Lee ◽  
Dae Geon Song ◽  
Won Sik Choy
Keyword(s):  
Chronic Pain ◽  
Glomus Tumor ◽  
Rare Condition ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Glomus Tumors ◽  
Contrast Magnetic Resonance ◽  
History Of ◽  
Subcutaneous Layer ◽  
Magnetic Resonance Imaging Mri

Introduction. A glomus tumor is a benign vascular tumor derived from glomus cells and occurs mainly in the subcutaneous layer of the subungual or digital pulp. Extradigital glomus tumors have been reported within the palm, wrist, forearm, foot, bone, stomach, colon, cervix, and mesentery. Glomus tumors can originate from the intraosseous, intramuscular, periosteal, intravascular, and intraneural layers. However, a glomus tumor originating from the intravascular layer of the forearm is a rare condition.Case Report. A 44-year-old woman had a 7-year history of chronic pain and focal tenderness of the forearm. No hypersensitivity or sensory alterations were observed. Contrast magnetic resonance imaging (MRI) showed a mass measuring 5 × 3 × 2 mm leading to a vein. Surgical excision was performed, and the tumor was completely resected. Finding of gross examination revealed a dark-red, well-defined soft tissue tumor, and histologic examination confirmed that the mass was a glomus tumor. The patient’s symptoms were completely resolved postoperatively.Conclusion. Intravascular glomus tumors rarely occur in the forearm; therefore, a thorough physical exam, comprehensive medical history, in-depth imaging, and early surgical excision upon clinical suspicion may be helpful to prevent a delayed or incorrect diagnosis.

scholarly journals Gastric schwannoma: a case report

2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Hayfa Romdhane ◽  
Myriam Cheikh ◽  
Zeineb Mzoughi ◽  
Sana Ben Slama ◽  
Rym Ennaifer ◽  
...  
Keyword(s):  
Epigastric Pain ◽  
Submucosal Tumor ◽  
Muscularis Propria ◽  
Partial Gastrectomy ◽  
Gastric Antrum ◽  
Submucosal Tumors ◽  
Gastric Schwannoma ◽  
One Year ◽  
Immunohistochemical Studies ◽  
Enhanced Computed Tomography

Schwannomas are generally benign, slow growing tumors. They are rarely observed in the gastrointestinal tract with the most common site being the stomach. These tumors are usually asymptomatic. The preoperative diagnosis <em>via</em> endoscopy is a challenging issue due to the difficulty of differentiation from other submucosal tumors. A 54-year-old woman presented with epigastric pain persisting for the last 10 months. Upper endoscopy revealed an elevated submucosal mass of the gastric antrum. The overlying mucosa was normal. Biopsy specimens yielded only unspecific signs of mild inactive chronic inflammation. Endoscopic ultrasound examination noted a hypoechoic homogeneous mass lesion located in the gastric antrum. The mass appeared to arise from the muscularis propria, and there was no perigastric lymphadenopathy. A contrast-enhanced computed tomography scan identified a homogeneous round mass and arising from the antrum of the stomach. Submucosal tumor was suspected and surgical intervention was recommended. The patient underwent an elective laparoscopic partial gastrectomy. The histopathologic features and immunohistochemical-staining pattern were consistent with a benign gastric schwannoma. Our patient shows no recurrence with a follow-up of one year. The definitive diagnosis of gastric schwannomas requires immunohistochemical studies. Complete margin negative surgical resection, as in this case, is the curative treatment of choice. The clinical course is generally benign.

scholarly journals Metastasis of breast cancer to bladder

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Asma Hadhri ◽  
Rim Abidi ◽  
Najet Mahjoub ◽  
Alia Mousli ◽  
Khalil Mahjoubi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lobular Carcinoma ◽  
Bladder Wall ◽  
Hormonal Treatment ◽  
Left Breast ◽  
Case Presentation ◽  
History Of ◽  
Bladder Metastasis ◽  
One Year ◽  
Immunohistochemical Studies

Abstract Background Breast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastasis. Urinary bladder metastasis from breast cancer is rarely reported in the literature. Case presentation We report a case of a 77-year-old female with history of left breast cancer, who presented a thickening of the bladder wall at pelvic ultrasound. Biopsy confirmed that the origin was lobular carcinoma of breast origin. The patient received chemotherapy, but the clinical course of the patient was very aggressive and she died one year later. Conclusion Bladder metastasis from breast cancer is rare, but the literature reveals an increase in such occurrence over the last few years. Pathologic diagnosis relies on immunohistochemical studies. Chemotherapy and hormonal treatment represent the standard therapy, with radiotherapy being used only to control bladder bleeding. The prognosis is usually poor.

scholarly journals Glomus Tumor of Uncertain Malignant Potential: A Rare Case Report

2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Mehta Shailee ◽  
◽  
Dabral Ritwika ◽  
Trivedi Priti ◽  
◽  
...  
Keyword(s):  
Soft Tissues ◽  
Glomus Tumor ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Current Case ◽  
Glomus Tumors ◽  
Large Size ◽  
Rare Case Report ◽  
Mitotic Figures

Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissues of the extremities and rarely in the visceral locations. Its bronchopulmonary origin is exceedingly rare clinical condition. The current case reported a 51-year-old male with dyspnea on exertion and obstructive pneumonia; he had a glomus tumor which has large size, deep location and exhibits an infiltrative margin as well as atypical mitotic figures. These characteristic suggests malignant behavior. Therefore diagnosis of glomus tumor of uncertain malignant potential was favored. Recently, the histopathological diagnostic criteria for malignant glomus tumors were defined in the WHO classification of soft tissue and bone tumors 4th edition. Here we also reviewed the literature on primary bronchopulmonary glomus tumors with special attention to the current concept of malignancy grade estimation.

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