scholarly journals Decolonization ofStaphylococcus aureusin Healthcare: A Dermatology Perspective

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Drew Kuraitis ◽  
Laura Williams

The bacteriumStaphylococcus aureusis responsible for significant morbidity, mortality, and financial burden in healthcare. It easily colonizes susceptible patients and can cause recurrent infections, especially in populations at risk. In addition to treating sequelae of infections, there is a growing body of literature aimed at decolonizing susceptible patients in order to prevent infection and also to prevent spread. Such strategies are widely employed in surgical, intensive care, and hospitalist fields.Staphylococcus aureusinvolvement has been implicated in the pathogenesis and persistence of many dermatologic diseases that are treated in the outpatient setting. This review serves to summarize current evidence for the management ofStaphylococcus aureuscolonized patients, as well as the evidence available for decolonization. We further characterize the role that colonization may play in atopic dermatitis, recurrent infections, hand eczema, cutaneous T-cell lymphoma, and also in surgical infections after Mohs surgery.

2021 ◽  
Vol 10 (4) ◽  
pp. 758
Author(s):  
Jason W. Lee ◽  
Tobi Somerville ◽  
Stephen B. Kaye ◽  
Vito Romano

Bacterial keratitis is a devastating condition that can rapidly progress to serious complications if not treated promptly. Certain causative microorganisms such as Staphylococcus aureus and Pseudomonas aeruginosa are notorious for their resistance to antibiotics. Resistant bacterial keratitis results in poorer outcomes such as scarring and the need for surgical intervention. Thorough understanding of the causative pathogen and its virulence factors is vital for the discovery of novel treatments to avoid further antibiotic resistance. While much has been previously reported on P. aeruginosa, S. aureus has been less extensively studied. This review aims to give a brief overview of S. aureus epidemiology, pathophysiology and clinical characteristics as well as summarise the current evidence for potential novel therapies.


2013 ◽  
Vol 69 (2) ◽  
pp. e82
Author(s):  
Minoru Fukuda ◽  
Tadashi Baba ◽  
Yuki Katayama ◽  
Teruyo Itou ◽  
Junko Kawasaki ◽  
...  

2015 ◽  
Vol 9 (1) ◽  
pp. 495-498 ◽  
Author(s):  
M James ◽  
W.S Khan ◽  
M.R Nannaparaju ◽  
J.S Bhamra ◽  
R Morgan-Jones

Since the introduction of laminar air flow in orthopaedic theatres by Sir John Charnley, it has widely become accepted as the standard during orthopaedic procedures such as joint arthroplasty. We present a review of available current literature for the use of laminar flow operating theatre ventilation during total joint arthroplasty and examines the effectiveness of laminar flow ventilated operating theatres in preventing post-operative wound infection. Results of our findings suggest that while bacterial and air particulate is reduced by laminar air flow systems, there is no conclusive effect on the reduction of post-operative wound infections following total joint arthroplasty. We conclude that a combination of strict aseptic technique, prophylactic antibiotics and good anaesthetic control during surgery remains crucial to reduce post-operative surgical infections.


2021 ◽  
pp. 0
Author(s):  
L Nørreslet ◽  
S Edslev ◽  
E Flachs ◽  
N Ebbehøj ◽  
P Andersen ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Akshyaya Pradhan ◽  
Ashish Tiwari ◽  
Rishi Sethi

Hypertension continues to be global pandemic with huge mortality, morbidity, and financial burden on the health system. Unfortunately, most patients with hypertension would eventually require two or more drugs in combination to achieve their target blood pressure (BP). To this end, emergence of more potent antihypertensive drugs is a welcome sign. Angiotensin receptor blockers (ARBs) are cornerstones of hypertension management in daily practice. Among all ARBs, azilsartan is proven to be more potent in most of the head-to-head trials till date. Azilsartan is the latest ARB approved for hypertension with greater potency and minimal side effects. This review highlights the role of azilsartan in management of hypertension in the current era.


2020 ◽  
Vol 83 (6) ◽  
pp. 442-449
Author(s):  
Line B. Nørreslet ◽  
Sofie M. Edslev ◽  
Paal S. Andersen ◽  
Frederik Plum ◽  
Jette Holt ◽  
...  

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