scholarly journals Bacterial Profile, Antibacterial Resistance Pattern, and Associated Factors from Women Attending Postnatal Health Service at University of Gondar Teaching Hospital, Northwest Ethiopia

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Abebaw Bitew Kifilie ◽  
Mulat Dagnew ◽  
Birhanemeskel Tegenie ◽  
Biruk Yeshitela ◽  
Rawleigh Howe ◽  
...  
Keyword(s):  
Health Service ◽  
Bacterial Infection ◽  
Associated Factors ◽  
Multidrug Resistant ◽  
Resistance Pattern ◽  
Resistant Bacteria ◽  
Antibacterial Resistance ◽  
Site Infection ◽  
Multidrug Resistant Bacteria ◽  
Study Participants

Introduction. Surgical site infection is a vital cause of maternal mortality and morbidity, especially in resource-limited countries. The rise of antibiotic resistance bacterial infection poses a big threat to this vulnerable population. However, there is lack of studies around the study area. Objective. The purpose of this study was to identify bacterial profile, antibacterial resistance pattern, and associated factors among mothers attending postnatal care health service. Methods. Institutional based cross-sectional study was conducted on 107 study participants at University of Gondar Teaching Hospital from 1 January 2016 to 30 May 2016. Wound swab, aspirate, and biopsy were collected and performed for culture and drug resistance testing. Data were entered and analyzed by using SPSS version 20. Bivariate and multivariate logistic regression models were fitted to determine the associated factors for bacterial infection. Odds ratio (95% CI) was calculated to determine the strength of statistically significant associated factors. Result. Bacterial growth was confirmed in 90 (84.1%) of 107 study participants suspected to have surgical site infection. The predominant bacterial isolates were S. aureus (41.6%), E. coli (19.8%), K. pneumoniae (13.9%), coagulase negative Staphylococcus (12.9%), and Enterobacter spp. (4%). The majority of isolates were resistant to ampicillin, amoxicillin, and tetracycline but susceptible to ceftriaxone and amikacin. Multidrug-resistant bacteria species were isolated. Using a procedure such as cesarean section and episiotomy for delivery and premature rapture of membrane had strong association with bacterial infection. Conclusion. The high prevalence of bacterial profile and isolation of multidrug-resistant bacteria pose a big threat to postnatal mothers and their children. Factors such as cesarean section, episiotomy for delivery, and premature rapture of membrane were predictors for bacterial infection. Therefore, there should be done a continuous surveillance as well as rational use of antibiotics and a longitudinal study using phenotypic and genotypic methods will be done.

Surgical site infection after liver transplantation in the era of multidrug-resistant bacteria: what new risks should be considered?

2021 ◽  
Vol 99 (1) ◽  
pp. 115220
Author(s):  
Maristela P. Freire ◽  
Alice T. Wan Song ◽  
Isabel Cristina Vilela Oshiro ◽  
Wellington Andraus ◽  
Luiz Augusto Carneiro D'Albuquerque ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Surgical Site Infection ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Site Infection ◽  
Multidrug Resistant Bacteria

Silver nanoparticles coated by green graphene quantum dots for accelerating the healing of MRSA-infected wounds

2020 ◽  
Vol 8 (23) ◽  
pp. 6670-6682 ◽  
Author(s):  
Xianghua Zhong ◽  
Chunyi Tong ◽  
Tiansheng Liu ◽  
Li Li ◽  
Xu Liu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Silver Nanoparticles ◽  
Bacterial Infection ◽  
Human Health ◽  
Graphene Quantum Dots ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Clinical Therapy ◽  
Infected Wounds

Bacterial infection, especially multidrug-resistant bacteria-induced infection, threatens human health seriously, which has posed great challenges for clinical therapy.

Multifunctional upconverting nanoparticles for near-infrared triggered and synergistic antibacterial resistance therapy

2014 ◽  
Vol 50 (72) ◽  
pp. 10488-10490 ◽  
Author(s):  
Meili Yin ◽  
Zhenhua Li ◽  
Enguo Ju ◽  
Zhenzhen Wang ◽  
Kai Dong ◽  
...  
Keyword(s):  
Near Infrared ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Antibacterial Resistance ◽  
Multidrug Resistant Bacteria

A novel nanomaterial with CuS nanoparticles decorated onto the surface of NaYF4:Mn/Yb/Er@photosensitizer doped SiO2 was synthesized for synergistic multidrug-resistant bacteria therapy.

scholarly journals Bacterial Multidrug Resistant Patterns Associated with Intensive Care Unit Infections in Akum, Cameroon

2020 ◽  
pp. 13-21
Author(s):  
Asakizi Augustine Nji ◽  
Forcham Emmanuel Duna
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Multidrug Resistant ◽  
Resistance Pattern ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Klebsiella Species ◽  
Microbiological Methods ◽  
Tract Infections ◽  
Hospital Associated Infections

Background: Patients admitted into the intensive care unit (ICU) usually have impaired immunity and are therefore at high risk of acquiring hospital associated infections. Infections caused by multidrug resistant bacteria now constitute a major problem, limiting the choice of antimicrobial therapy. Objectives: This study was aimed at determining the antimicrobial resistance pattern of pathogens causing ICU infections at the Catholic Holy Family Hospital Akum-Bamenda. The etiological agents, prevalence and types ICU infections were also determined. Methods: Thirteen months hospital associated infections surveillance was conducted in the hospital for patients admitted into ICU. Blood, urine, tracheal aspirate and wound biopsies specimens were collected under strict asepsis and sent to the Medical Microbiology laboratory of the same institution for immediate processing. All pathogens were isolated and identified by standard microbiological methods. Disk diffusion antibiotic susceptibility testing was performed and interpreted according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: The overall prevalence of ICU infections was 30.9% out of which 12.9% were bloodstream infections, 31.5% urinary tract infections, 38.9% pneumonia, and 16.7% skin and soft tissue infections. Klebsiella species and Escherichia coli were the predominant pathogens. Multidrug resistant organisms constituted 59.3% of the pathogens, MDR Klebsiella spp and MDR E. coli were 70.8% and 71.4% respectively. Resistance to Cefuroxime was the highest (92.9%) while Meropenem had the least resistance (21.4%). Conclusion: There is a high prevalence of multidrug resistant bacteria causing ICU infections.  With the advent of covid-19, infection control procedures and institution of functional antimicrobial stewardship are needed to be put in place in order to cover come this herculean task.

scholarly journals Characterization of Multidrug Resistant Bacteria Isolated from Hospital Environment

2020 ◽  
Vol 10 (2) ◽  
pp. 94-101
Author(s):  
Saba Irshad ◽  
Humaira Yasmeen
Keyword(s):  
Multidrug Resistance ◽  
Financial Burden ◽  
Multidrug Resistant ◽  
Hospital Environment ◽  
Diffusion Method ◽  
Resistance Pattern ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Hospital Waste ◽  
Bacillus Spp

Background: Unveiling of multidrug resistance in bacteria is becoming a global concern. It contributes as a main financial burden to treat infectious diseases especially in developing countries. Objectives: This study was designed to determine the prevalence and resistance pattern of multidrug resistant bacteria from hospital soil. Methodology: Using random soil sampling technique, bacterial isolates were obtained through dilution plate method. Antimicrobial screening of isolates was performed by Kirby Bauer disc diffusion method against a panel of 14 known antibiotics. Furthermore, strains were biochemically identified following Bergey’s Manual of Determinative Bacteriology. Results: A total of 44 isolates were successfully identified from 4 soil samples of different waste areas of hospital from Multan region. Bacillus spp. and Staphylococcus ssp. were prominent isolates in all the sites. Resistance among Bacillus spp. was high against ampicillin (91%) and in Staphylococcus spp. against tetracycline (78%). Out of total strains, 35 were found to be multidrug resistant. Conclusion: Presence of drug residue in the hospital waste contributes to its resistance in bacteria. A substantial increase of multidrug resistance in hospital waste demands an effective management against drugs.

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