scholarly journals Microfluidic Preparation of Liposomes Using Ethyl Acetate/n-Hexane Solvents as an Alternative to Chloroform

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Eunhye Yang ◽  
Hyunjong Yu ◽  
Jun-Young Park ◽  
Kyung-Min Park ◽  
Pahn-Shick Chang
Keyword(s):  
Phase Separation ◽  
Physicochemical Properties ◽  
Ethyl Acetate ◽  
Critical Issue ◽  
Optimum Ratio ◽  
Nutrient Delivery ◽  
Food Industries ◽  
Random Combination ◽  
Liposome Solution ◽  
Halogenated Solvents

Although liposomes have been used as a nutrient delivery carrier in the pharmaceutical, cosmetic, and food industries, they still suffer from the critical issue caused by the use of halogenated solvents (e.g., chloroform), which may be harmful to humans. Nonhalogenated solvents have been screened as candidate substitutes for chloroform based on their physicochemical properties. However, none of the candidates examined to date could form stable inverted micelles when used alone. Here, to obtain physicochemical properties similar to chloroform, combined mixtures were prepared using various ratios of each candidate. Based on the results of random combination trials with numerous candidates, ethyl acetate: n-hexane = 4 : 1(v/v) was selected as the optimum ratio because it could form stable inverted micelles and a transparent liposome solution without phase separation. The ethyl acetate and n-hexane mixture are a potential substitute for chloroform, which may resolve concerns regarding the toxicity of residual halogenated solvents in lipid nanovesicles.

Electrospinning as a Versatile Method of Composite Thin Films Fabrication for Selected Applications

2019 ◽  
Vol 293 ◽  
pp. 35-49 ◽  
Author(s):  
Wiktor Matysiak ◽  
Tomasz Tański ◽  
Weronika Smok
Keyword(s):  
Thin Films ◽  
Phase Separation ◽  
Physicochemical Properties ◽  
Template Synthesis ◽  
Self Assembly ◽  
Textile Industry ◽  
Separation Method ◽  
Common Method ◽  
High Quality ◽  
Composite Thin Films

Today, one of the most popular nanomaterials are thin nanofibrous layers, which are used in many fields of industry, eg electronics, optics, filtration and the textile industry. They can be produced by various methods, such as drawing, template synthesis, molecular self-assembly or phase separation method, but the most common method is electrospinning from a solution or melts. Electrospinning is gaining more and more interest due to its versatility, simplicity and economy as well as the possibility of producing fibers from various types of polymeric, ceramic and metalic materials. Nanofibrous layers produced by this method are characterized by high quality and the desired physicochemical properties.

Promoting Effects of Al on Ni-Based Catalyst for the Hydrodeoxygenation Performance of Ethyl Acetate

2019 ◽  
Vol 17 (12) ◽  
Author(s):  
Caixia Miao ◽  
Fengjiao Wang ◽  
Guilin Zhou ◽  
Hongmei Xie ◽  
Zhaojie Jiao ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Ethyl Acetate ◽  
Atmospheric Pressure ◽  
Active Component ◽  
Adsorption Property ◽  
Good Stability ◽  
Active Components ◽  
Al Content

Abstract The mesoporous Ni20/Al-KIT-6 (denoted as N20AxK) catalysts with different Al content (1–9 wt%) were prepared, metal Ni and KIT-6 modified by Al were used as active component and support, respectively. The physicochemical properties of the prepared N20AxK catalysts were characterized by H2-TPR, XRD, BET, TEM, and H2-TPD. The catalytic hydrodeoxygenation(HDO) performance of N20AxK catalysts was evaluated by ethyl acetate catalytic HDO. The results show that the catalytic HDO performance of the prepared N20AxK catalysts is related to the adsorption and activation performance for H2 molecules, as well as the dispersion of matal Ni active components. N20A5K catalyst shows the best H2 adsorption property and Ni dispersion. N20A5K catalyst presents superior catalytic HDO performance. At 300 °C and atmospheric pressure, the conversion of ethyl acetate and ethane selectivity of N20A5K catalyst are 99.3 % and 97.4 %, respectively. Besides, the N20A5K catalyst exhibits good stability.

Novel porphyrin-labelled poly(N-isopropylacrylamides): syntheses from bromoalkyl-containing prepolymers and physicochemical properties

2000 ◽  
Vol 04 (06) ◽  
pp. 579-587 ◽  
Author(s):  
YURI S. AVLASEVICH ◽  
TIMOUR A. CHEVTCHOUK ◽  
VALERY N. KNYUKSHTO ◽  
OLEG G. KULINKOVICH ◽  
KONSTANTIN N. SOLOVYOV
Keyword(s):  
Phase Transition ◽  
Phase Separation ◽  
Physicochemical Properties ◽  
Absorption Spectra ◽  
Polymer Solutions ◽  
Soret Band ◽  
Water Soluble ◽  
Absorption Bands ◽  
Aqueous Polymer ◽  
Peak Intensity

Novel water-soluble tetraarylporphyrin-labelled polymers have been synthesized by the reaction of bromoalkyl-containing poly(N-isopropylacrylamides) with 5-(4-pyridyl)-10,15,20-tri(4-methoxyphenyl) porphyrin. Corresponding Zn -porphyrin-containing polymers have also been prepared. Phase transition diagrams show that aqueous polymer solutions exhibit phase separation upon heating. Absorption spectra of the porphyrin-labelled polymers have been recorded in water and organic solvents. It is found that the absorption bands in aqueous polymer solutions are broadened and shifted bathochromically, the peak intensity of the Soret band in the polymer spectra being strongly lowered in water. Fluorescence properties of the polymers are briefly reported.

scholarly journals Characterization of Structural and Physicochemical Properties of an Exopolysaccharide Produced by Enterococcus sp. F2 From Fermented Soya Beans

2021 ◽  
Vol 12 ◽  
Author(s):  
Guangyang Jiang ◽  
Longzhan Gan ◽  
Xiaoguang Li ◽  
Juan He ◽  
Shihao Zhang ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Edible Oils ◽  
Gel Filtration ◽  
Alternative Source ◽  
Excellent Thermal Stability ◽  
Spectral Techniques ◽  
Food Industries ◽  
Functional Additives ◽  
Potential Alternative ◽  
High Concentrations

The present study sought to isolate a novel exopolysaccharide (EPS-F2) from Enterococcus sp. F2 through ethanol precipitation, anion-exchange, and gel-filtration chromatography and characterize the physicochemical properties by spectral techniques. EPS-F2 was identified as a neutral homo-exopolysaccharide composed of only glucose with a high molecular weight of 1.108 × 108 g/mol. It contained →6)-α-D-Glcp-(1→ linkage in the main chain and →3, 6)-α-D-Glcp-(1→ branch chain). Moreover, EPS-F2 possessed excellent thermal stability (266.6°C), water holding capacity (882.5%), oil holding capacity (1867.76%), and emulsifying activity against various edible oils. The steady shear experiments exhibited stable pseudo plasticity under various conditions (concentrations, temperatures, and pHs). The dynamic oscillatory measurements revealed that EPS-F2 showed a liquid-like behavior at a low concentration (2.5%), while a solid-like behavior at high concentrations (3.0 and 3.5%). Overall, these results suggest that EPS-F2 could be a potential alternative source of functional additives and ingredients and be applied in food industries.

A one-pot method for the synthesis of 3-(hetero-)aryl-1,4,2-dioxazol-5-ones

2020 ◽  
Vol 98 (3) ◽  
pp. 158-163 ◽  
Author(s):  
Toren Hynes ◽  
David S. Hall ◽  
Alexander W.H. Speed ◽  
Jason D. Masuda ◽  
J.R. Dahn
Keyword(s):  
Ethyl Acetate ◽  
Lithium Ion Batteries ◽  
Hydroxamic Acid ◽  
Room Temperature ◽  
Lithium Ion ◽  
Environmentally Benign ◽  
One Pot ◽  
Electrolyte Additives ◽  
Reaction Proceeds ◽  
Halogenated Solvents

3-R-1,4,2-dioxazol-5-ones are a class of compounds that are increasingly finding diverse uses, including as regioselective amidation reagents and as electrolyte additives that enable long cycling lifetimes in rechargeable lithium-ion batteries. Conventional methods for their synthesis tend to be slow and time-consuming, requiring isolation and thorough drying of a hydroxamic acid intermediate, followed by a separate cyclization step with N,N′-carbonyldiimidazole. Furthermore, the cyclization is typically performed in dichloromethane, an environmentally harmful solvent. This work demonstrates a new one-pot method for the synthesis of these compounds that eliminates the need for isolation of the intermediate or the use of halogenated solvents. The reaction is mainly performed using environmentally benign ethyl acetate and a relatively small amount of N,N-dimethylformamide. The reaction proceeds readily at room temperature and requires no expensive metal catalysts to function.

Identification of Biflavones in Ethyl Acetate Fraction from Ethanol Extract of Selaginella doederleinii Hieron

2012 ◽  
Vol 550-553 ◽  
pp. 1862-1865
Author(s):  
Yan Zhang ◽  
Li Yang ◽  
Lin Wang
Keyword(s):  
Physicochemical Properties ◽  
Ethyl Acetate ◽  
Dimethyl Ether ◽  
Spectroscopic Data ◽  
Chemical Constituents ◽  
Ethanol Extract ◽  
Ethyl Acetate Fraction ◽  
Chemical Structures ◽  
Trimethyl Ether ◽  
First Time

The chemical constituents were isolated from the ethyl acetate fraction from ethanol extract of Selaginella doederleinii Hieron by column chromatography on silica gel and Sephadex LH-20. The chemical structures of six biflavones were elucidated on the basis of physicochemical properties and spectroscopic data as amentoflavone (1), robustaflavone 7,4',7''-o-trimethyl ether (2), heveaflavone (3), podocarpusflavone A (4), robustaflavone 4',4'''-o-dimethyl ether (5) and robustaflavone 4'-o-methyl ether (6). Biflavones 2, 4 and 5 were obtained from Selaginella doederleinii Hieron for the first time.

Sign in / Sign up

Export Citation Format

Share Document