scholarly journals The Relationship between Simple Snoring and Metabolic Syndrome: A Cross-Sectional Study

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Juanjuan Zou ◽  
Fan Song ◽  
Huajun Xu ◽  
Yiqun Fu ◽  
Yunyan Xia ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Linear Trend ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Linear Trend ◽  
The Relationship ◽  
Multivariable Adjustment ◽  
Simple Snoring

Purpose. This cross-sectional study was performed to assess the relationship between simple snoring and metabolic syndrome (MetS).Methods. A total of 5635 participants including 300 healthy volunteers without snoring allegedly were initially included from 2007 to 2016. Polysomnographic variables, anthropometric measurements, and biochemical indicators were collected. The polynomial linear trend test was used to assess the linear trend across snoring intensity for metabolic score, and logistic regression was used to evaluate the odds ratios (ORs) for MetS after controlling for age, sex, obesity, smoking status, and alcohol consumption.Results. The final study population consisted of 866 participants. Simple snorers showed more severe metabolic disorders and higher prevalence of MetS than nonsnorers. A significant linear trend was observed between snoring intensity and metabolic score. Simple snoring was significantly associated with increased odds for MetS among all participants (OR=2.328, 95% CI: 1.340–4.045) and female participants (OR=2.382, 95% CI: 1.136–4.994) after multivariable adjustment. With regard to MetS components, simple snoring was significantly associated with increased odds for hypertension (OR=1.730, 95% CI: 1.130–2.650), abdominal obesity (OR=1.810, 95% CI: 1.063–3.083), and hyper-triglycerides (TG) (OR=1.814, 95% CI: 1.097–2.998) among all participants, with hypertension (OR=3.493, 95% CI: 1.748–6.979) among males and with abdominal obesity (OR=2.306, 95% CI: 1.245–4.270) and hyper-TG (OR=2.803, 95% CI: 1.146–6.856) among females after multivariable adjustment.Conclusions. After excluding the influence of repeated apnea and hypoxia, simple snoring was still significantly associated with MetS, especially in women. Furthermore, the associations were more obvious for hypertension among males and for abdominal obesity and hyper-TG among females. In addition to OSA, simple snoring also should be valued.

scholarly journals Effect of number of medications and use of potentially inappropriate medications on frailty among early-stage older outpatients

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuya Uragami ◽  
Kazuhiro Takikawa ◽  
Hajime Kareki ◽  
Koji Kimura ◽  
Kazuyuki Yamamoto ◽  
...  
Keyword(s):  
Early Stage ◽  
Linear Trend ◽  
Cross Sectional Study ◽  
Potentially Inappropriate Medications ◽  
Sectional Study ◽  
Antithrombotic Drugs ◽  
Cross Sectional ◽  
The Relationship ◽  
Inappropriate Medications ◽  
Frailty Score

Abstract Background Frailty is an urgent concern among an aging population worldwide. However, the relationship between frailty and number and types of medications has not been studied in detail among early-stage older patients, and it is unclear what prescriptions may have a role in preventing frailty. This study aimed to clarify the effects of number of medications and use of potentially inappropriate medications (PIMs) on frailty among early-stage older outpatients in Japan. Methods A cross-sectional study was undertaken. Frailty scores and medications of outpatients aged 65–74 years who regularly visited community pharmacies were investigated. Frailty scores were classified as 0 (non-frailty), 1–2 (pre-frailty), and ≥ 3 (frailty). The association between frailty and number of medications was analyzed by age and compared between PIM use and non-use groups. The proportion of patients who used PIMs was also analyzed by frailty score. Results Of 923 older outpatients, 49 (5.3%) and 318 (34.5%) patients had frailty and pre-frailty scores, respectively. The numbers of medications among patients with pre-frailty and frailty were significantly higher than among those with non-frailty (p <  0.001 for both). A similar increase was shown for PIM use groups aged 69–71 and 72–74 years, but not for the PIM use group aged 65–68 years and all groups without PIM use. An increasing linear trend was observed for the relationship between the proportion of patients who used any PIM, as well as some subcategories of PIMs (such as NSAIDs, benzodiazepines, loop diuretics and antithrombotic drugs) and frailty score. Conclusions Unnecessary medication use among early-stage older outpatients, especially patients aged ≥69 years who use PIMs and many medications, seems to be associated with frailty, but further research is needed to confirm these findings.

The Relationship Between Recommended and None Recommended Food Scores on Cardiovascular Risk Factors in Obese and Overweight Adult Women: A Cross Sectional Study

2020 ◽  
Author(s):  
Maryam Sabbari ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Abdominal Obesity ◽  
Lower Risk ◽  
Cross Sectional Study ◽  
Composition Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

Abstract Objective: No studies have examined the relationship between recommended food score (RFS), none recommended food score (NRFS) and cardiovascular risk factors. This study was conducted to evaluate the association of RFS and NRFS with cardiovascular risk factors in overweight and obese women.Methods: This cross-sectional study was performed on 379 overweight and obese (BMI ≥25 kg/m2) women aged 18-48 years. Anthropometric measurements and body composition analysis were assessed in all participants. Dietary intake was assessed by a valid and reliable food frequency questionnaire (FFQ) containing 147 items and RFS and NRFS calculated. Biochemical assessments including TC, HDL, LDL, TG, FBS, insulin, HOMA-IR and hs-CRP were quantified by ELISA.Results: The mean age and BMI of participants were 36.73±9.21 (y) and 31.17±4.22 (kg/m²) respectively. Binary logistic analysis showed that participants in the highest quartile of the RFS compared to the lowest quartile had 82% lower risk for Hypertriglyceridemia [OR=0.18, 95%CI=0.06-0.53, P=0.002] and 91% lower risk for abdominal obesity [OR=0.09, 95%CI=0.008-1.04, P=0.05]. in addition, Participants who were in the highest quartile of the RFS compared to the lowest quartile had lower HOMA-IR [OR=0.29, 95%CI=0.08-1.00, P=0.05]. subjects with high adherence to the NRFS had lower HDL [OR=2.11, 95%CI=1.08-4.12, P=0.02] and higher risk for Hypertriglyceridemia [OR=2.95, 95%CI=1.47-5.94, P=0.002] compared to low adherence. Conclusions: There was an inverse significant association between adherence to RFS and risk of Hypertriglyceridemia, insulin resistance, and abdominal obesity. There was a significant association between NRFS and Hypertriglyceridemia, and also we found an inverse relationship between NRFS and HDL.

scholarly journals Gender Differences in the Association between Sleep Duration and Cardiometabolic Risk: A Cross-sectional Study

2020 ◽  
Author(s):  
Rei Matsuo ◽  
Shigemasa Tani ◽  
Naoya Matsumoto ◽  
Yasuo Okumura
Keyword(s):  
Metabolic Syndrome ◽  
Gender Differences ◽  
Risk Factor ◽  
Waist Circumference ◽  
Sleep Duration ◽  
Cardiometabolic Risk ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

Abstract Background: Inappropriate sleep duration (shorter/longer than optimal sleep duration) has come to be identified as a potential cardiometabolic risk factor, and thereby, as a risk factor for atherosclerotic cardiovascular disease (ASCVD). Few data exist regarding the gender differences in the relationship between sleep duration and cardiometabolic risk.Methods: This cross-sectional study was conducted in a study population of 9262 apparently healthy (5004 male, 4258 female) subjects at the Health Planning Center of Nihon University Hospital between September, 2015, and October 2016.Results: In the male subjects, as compared to a sleep duration of 6 to 7 hours, a sleep duration of ³8 hours was associated with an odds ratio (OR) for abdominal obesity (defined according to the Japanese criteria for metabolic syndrome as a waist circumference of ³85 cm) of 1.31 (95% confidence interval [CI], 1.004-1.71) and for a non-high-density lipoprotein cholesterol level of ³150 mg/dL (defined as “Borderline hyper” by the Japan Atherosclerosis Society Guidelines for Prevention of ASCVD 2017) of 1.33 (1.05-1.68), and a sleep duration of <5 hours was associated with an OR (95% CI) for a fasting blood glucose of ³100 mg/dL (defined as “high” by a specialized lifestyle checkup program for the detection of symptoms of metabolic syndrome in Japan) of 1.74 (1.25-2.42). On the other hand, in the female subjects, as compared to a sleep duration of 6 to 7 hours, a sleep duration of <5 hours was associated with an OR (95% CI) for abdominal obesity (waist circumference ³90 cm) of 1.98 (1.11-3.55) and for a hemoglobin A1c (HbA1c) level of ³5.6 % of 1.52 (1.10-2.10), whereas a sleep duration of ³8 hours was not associated with worsening of any of the examined cardiometabolic risk factors. Conclusions: There may be gender differences in the relationship between sleep duration and cardiometabolic risk. To further reduce the risk of ASCVD, it may be of particular importance to emphasize adequate sleep duration.Clinical Trial Registration: UMIN (http://www.umin.ac.jp/) Study ID:　 UMIN000037643 retrospectively registered on 9 August 2019

scholarly journals Positive association of SCD1 genetic variation and metabolic syndrome in dialysis patients in China

2020 ◽  
Vol 17 (2) ◽  
pp. 111-119
Author(s):  
Yanyan Guo ◽  
Zibo Xiong ◽  
Meiling Su ◽  
Limin Huang ◽  
Jinlan Liao ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Genetic Variation ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Renal Diseases ◽  
Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Aim: Metabolic syndrome (MetS) diagnosed in the dialysis patients is increasingly reported which worsens the prognosis of the renal diseases. The relationship of SCD1 with MetS is largely unknown. The purpose of this study was to investigate the relationship between SCD1 polymorphism and MetS in dialysis patients. Methods: A cross-sectional study was conducted on 323 Chinese dialysis patients, and the correlation between the seven SNPs of SCD1 gene (rs10883465, rs2060792, rs1502593, rs522951, rs3071, rs3978768 and rs1393492) and MetS was analyzed. Results: One tag-SNP (rs1393492) has significantly associated with the prevalence of MetS. Dialysis patients with rs1393492 AA genotype of SCD1 are more prone to MetS (p = 0.021). Conclusion: This study shows that the rs1393492 variations of SCD1 gene are related with the development of MetS in Chinese dialysis patients.

scholarly journals Dietary patterns and their association with the components of metabolic syndrome: A cross-sectional study of adults from northeast Thailand

F1000Research ◽  
2019 ◽  
Vol 7 ◽  
pp. 905
Author(s):  
Pornpimon Chupanit ◽  
Benja Muktabhant ◽  
Frank Peter Schelp
Keyword(s):  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Cross Sectional Study ◽  
Food Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mixed Pattern ◽  
Traditional Pattern

Background:Nutritional transition influences a shift in eating behaviour that is associated with a rise in the prevalence of non-communicable diseases (NCDs). Metabolic syndrome (MetS) comprises a set of NCD risk factors. This study aimed to investigate dietary patterns and to determine the relationship between dietary patterns and MetS and its components.Methods:An analytical cross-sectional study was conducted among 468 adults aged 35–60 years who were residents of a semi-urban district of one of the central provinces in the northeast of Thailand. A factor analysis identified dietary patterns based on the consumption of 21 food groups, which were assessed by using a semi-quantitative food frequency questionnaire. MetS was identified by using the harmonized criteria that were stipulated by six leading international organisations. The association between dietary patterns and MetS and its components were evaluated by multiple logistic regressions. The confounding factors adjusted in the model were age, sex, smoking status, physical activity, and medication intake.Results:Two dietary patterns were identified: a traditional pattern characterised by high intakes of sticky rice and animal source foods; a mixed pattern included high intakes of white rice and a variety of food groups. The two dietary patterns did not show any association with MetS. Participants in the highest tertile of the traditional pattern was significantly related to high triglycerides (adjusted OR = 1.74, 95% CI: 1.10–2.88), in comparison to those from the lowest tertile, whereas participants in the highest tertile of the mixed pattern was inversely associated with abdominal obesity (adjusted OR= 0.49, 95% CI: 0.30–0.81) than those in the lowest tertile.Conclusions:Adherence to a traditional dietary pattern among the northeast Thai adults, in the context of nutrition transition, was associated with high triglyceride levels while the mixed dietary pattern was inversely related to abdominal obesity.

scholarly journals The Relationship and Gender Disparity Between Thyroid Nodules and Metabolic Syndrome Components Based on a Recent Nationwide Cross-Sectional Study and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Fan Zhang ◽  
Yongze Li ◽  
Xiaohui Yu ◽  
Xichang Wang ◽  
Zheyu Lin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
Cross Sectional Study ◽  
Cochrane Library ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

BackgroundMetabolic syndrome (MetS) has a potential connection with thyroid disease, but its relationship with thyroid nodules (TNs) is still controversial. This study aims to clarify the relationship between MetS and TNs, and this relationship in the subgroup of gender.MethodsThe recent nationwide cross-sectional study called Thyroid Disorders, Iodine Status, and Diabetes Epidemiological survey provided the newest data on the relationship between MetS and TNs from China and included 56,729 subjects. We also researched related literature in PubMed, EMBASE, Cochrane Library, and MEDLINE until Oct 30, 2020, in order to perform a meta-analysis. The relevant articles were examined, and the eligible studies were included to assess the association between MetS and TNs.ResultsThe meta-analysis included 15 studies (involving 468,845 subjects). Of these, 14 studies were from the databases, and one study was this cross-sectional data. The meta-analysis showed that TNs were associated with a higher prevalence of MetS (OR=1.87, 95% CI: 1.44–2.45) and the components of MetS, including central obesity (OR=1.41, 95% CI: 1.15–1.72), hypertriglyceridemia (OR=1.13, 95% CI: 1.10–1.15), low high-density lipoprotein cholesterolemia (OR=1.11, 95% CI: 1.02–1.20), abnormal blood pressure (OR=1.68, 95% CI: 1.62–1.75), and hyperglycemia (OR=1.59, 95% CI: 1.46–1.74). Central obesity displayed gender differences, being a risk factor in males (OR=1.38, 95% CI: 1.02–1.86) but not in females (OR=1.47, 95% CI: 0.97–2.23).ConclusionTNs were indeed associated with a higher prevalence of MetS. In addition, its component diseases, such as central obesity, hypertriglyceridemia, abnormal blood pressure, and hyperglycemia, were also associated with TNs. Females with MetS or its components had a higher risk of suffering from TNs than males.

scholarly journals C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Feiyu Jiang ◽  
Min Yang ◽  
Xili Zhao ◽  
Rui Liu ◽  
Gangyi Yang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Multiple Stepwise Regression Analysis ◽  
Glucose And Lipid Metabolism ◽  
Study Population ◽  
The Relationship

Objective. C1q/TNF-related protein5 (CTRP5) is a member of the C1q/tumor necrosis factor α- (TNF-α-) related protein family and has been reported to be associated with the regulation of glucose and lipid metabolism. However, the clinical association between CTRP5 and metabolic syndrome (MetS) has not been reported. The aim of the current study is to investigate the association between CTRP5 and MetS by a cross-sectional study. Methods. We performed a cross-sectional study in a Chinese population including 89 controls and 88 MetS individuals. Serum CTRP5 concentrations were determined by ELISA. The relationship between circulating CTRP5 and MetS and insulin resistance (IR) was assessed by Spearman’s correlation and multiple stepwise regression analysis. Results. Circulating CTRP5 concentrations were markedly decreased in MetS individuals relative to normal adults. Overweight/obese individuals (BMI ≥ 25 kg/m2) showed a lower serum CTRP5 level than lean subjects (BMI < 25 kg/m2) in the study population (124.1 (99.12–147.37) vs. 103.9 (79.15–124.25) μg/L; P<0.01). Circulating CTRP5 was found to be correlated negatively with BMI, FAT%, FBG, WHR, SBP, HbA1c, TG, 2-hour blood glucose after glucose overload (2-hOGTT), FIns, and HOMA-IR and positively with HDL-C (P<0.05 or P<0.01). Binary logistic regression revealed that serum CTRP5 levels were associated with MetS. In addition, serum CTRP5 levels gradually decreased with the increase in MetS components. Conclusions. Circulating CTRP5 is relative to the elevated risk of MetS in humans and may be in part through the effect of insulin resistance. This trial is registered with ChiCTR-OCS-13003185.

scholarly journals Dietary patterns and their association with the components of metabolic syndrome: A cross-sectional study of adults from northeast Thailand

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 905 ◽  
Author(s):  
Pornpimon Chupanit ◽  
Benja Muktabhant ◽  
Frank Peter Schelp
Keyword(s):  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Cross Sectional Study ◽  
Food Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mixed Pattern ◽  
Traditional Pattern

Background:Nutritional transition influences a shift in eating behaviour that is associated with a rise in the prevalence of non-communicable diseases (NCDs). Metabolic syndrome (MetS) comprises a set of NCD risk factors. This study aimed to investigate dietary patterns and to determine the relationship between dietary patterns and MetS and its components.Methods:A cross-sectional study was conducted among 468 healthy adults aged 35–60 years who were residents of a semi-urban district of one of the central provinces in the northeast of Thailand. A factor analysis identified dietary patterns based on the consumption of 21 food groups, which were assessed by using a semi-quantitative food frequency questionnaire. MetS was identified by using the harmonized criteria that were stipulated by six leading international organisations. The association between dietary patterns and MetS and its components were evaluated by multiple logistic regressions. The confounding factors adjusted in the model were age, sex, smoking status, physical activity, and medication intake.Results:Two dietary patterns were identified: a traditional pattern characterised by high intakes of sticky rice and animal source foods; a mixed pattern included high intakes of white rice and a variety of food groups. The two dietary patterns did not show any association with MetS. Participants in the highest tertile of the traditional pattern was significantly related to high triglycerides (adjusted OR = 1.74, 95% CI: 1.10–2.88), in comparison to those from the lowest tertile, whereas participants in the highest tertile of the mixed pattern was inversely associated with abdominal obesity (adjusted OR= 0.49, 95% CI: 0.30–0.81) than those in the lowest tertile.Conclusions:Adherence to a traditional dietary pattern among the northeast Thai adults, in the context of nutrition transition, was associated with high triglyceride levels while the mixed dietary pattern was inversely related to abdominal obesity.

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