scholarly journals Application Research of “Field” Theory in the Problem of Colleges and Universities Innovation Team Aggregation

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
HongJing Liang ◽  
JinSheng Liu ◽  
Rong Wang ◽  
YaQin Song ◽  
YuanYuan Zhou
Keyword(s):  
Field Theory ◽  
Growth Factor ◽  
Colleges And Universities ◽  
Application Research ◽  
Growth Path ◽  
Academic Leaders ◽  
Innovation Teams ◽  
Virtuous Cycle ◽  
The Individual ◽  
Innovation Team

Based on the field theory in physics, the thesis applies model construction and other methods to apply the research on the agglomeration problem of colleges’ and universities’ innovation teams and constructs the growth field model of colleges’ and universities’ innovation teams. The conclusions show that the “growth field” of the colleges’ and universities’ innovation team is composed of two elements: “hidden growth factor” and “dominant growth factor,” which have the directional and force acting; if the growth force is more powerful than the resistance, the team growth will move forward along the growth path; if the resultant force is greater than the power, it will enter the recession or be stagnant in advance. The growth path is different in the magnitude and direction of the force at each stage, and the growth path of the individual members of the team and the team as a whole is also different; there is agglomeration in the growth field, and the excellent academic leaders are particularly important. It is a process in which the field forces overlap each other, which will form a situation of continuous agglomeration and a virtuous cycle of interaction and find out the ways to integrate and enhance the ability of colleges’ and universities’ innovation teams under the field effect, in order to achieve the goal of attracting talents to join, optimizing and integrating within the team, improving the overall ability of the team, and increasing outputs.

Emerson's Atom and the Matter of Suffering

2009 ◽  
Vol 64 (1) ◽  
pp. 16-47
Author(s):  
Mark Noble
Keyword(s):  
Field Theory ◽  
Natural History ◽  
Classical Field Theory ◽  
Classical Field ◽  
The Other ◽  
History Of ◽  
The One ◽  
The Individual ◽  
Solid Bodies ◽  
Lines Of Force

This essay argues that Ralph Waldo Emerson's interest in the cutting-edge science of his generation helps to shape his understanding of persons as fluid expressions of power rather than solid bodies. In his 1872 "Natural History of Intellect," Emerson correlates the constitution of the individual mind with the tenets of Michael Faraday's classical field theory. For Faraday, experimenting with electromagnetism reveals that the atom is a node or point on a network, and that all matter is really the arrangement of energetic lines of force. This atomic model offers Emerson a technology for envisioning a materialized subjectivity that both unravels personal identity and grants access to impersonal power. On the one hand, adopting Faraday's field theory resonates with many of the affirmative philosophical and ethical claims central to Emerson's early essays. On the other hand, however, distributing the properties of Faraday's atoms onto the properties of the person also entails moments in which materialized subjects encounter their own partiality, limitation, and suffering. I suggest that Emerson represents these aspects of experience in terms that are deliberately discrepant from his conception of universal power. He presumes that if every experience boils down to the same lines of force, then the particular can be trivialized with respect to the general. As a consequence, Emerson must insulate his philosophical assertions from contamination by our most poignant experiences of limitation. The essay concludes by distinguishing Emersonian "Necessity" from Friedrich Nietzsche's similar conception of amor fati, which routes the affirmation of fate directly through suffering.

Ecological field theory model: a mechanistic approach to simulate plant–plant interactions in southeastern forest ecosystems

1993 ◽  
Vol 23 (10) ◽  
pp. 2180-2193 ◽  
Author(s):  
Pu Mou ◽  
Robert J. Mitchell ◽  
Robert H. Jones
Keyword(s):  
Field Theory ◽  
Loblolly Pine ◽  
Vegetation Dynamics ◽  
Plant Size ◽  
Theory Model ◽  
Plant Interactions ◽  
Simulation Accuracy ◽  
Individual Level ◽  
The Individual ◽  
Plant Plant

Ecological field theory, unlike many other vegetation modeling approaches, provides a basis to construct an individually based, spatially explicit, and resource-mediated model for mechanistic simulation of plant–plant interactions and vegetation dynamics. The model REGROW has been developed, based on ecological field theory principles, to simulate vegetation dynamics for northern hardwood forests. Using data from a current study of a southern pine system to calibrate a modified version of this model, SPGROW, we simulated growth of individuals for the first growing season in stands of loblolly pine (Pinustaeda L.) and sweetgum (Liquidambarstyraciflua L.) seedlings and loblolly pine seedling–sweetgum sprout mixtures. SPGROW accurately simulated stand development at population and stand levels. However, less agreement occurred at the individual level between simulated and field survey values, possibly owing to lack of data on site heterogeneity and genetic variation. Plant interactions, which altered resource availability (light, water, and nutrients) to individual plants, played a major role in differentiating plant size in the model. Given its unique model structure and simulation accuracy, SPGROW has the potential to provide very detailed insight into the mechanisms of plant–plant interactions.

Differential trans activation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4

1990 ◽  
Vol 10 (8) ◽  
pp. 3934-3944
Author(s):  
K E Yutzey ◽  
S J Rhodes ◽  
S F Konieczny
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Transcriptional Activation ◽  
Muscle Development ◽  
Fibroblast Growth ◽  
Temporal Expression ◽  
Regulatory Factors ◽  
In Trans ◽  
Muscle Regulatory Factors ◽  
The Individual

Expression of the mammalian muscle regulatory factors MyoD1, myogenin, and MRF4 will convert C3H10T1/2 fibroblasts to stable muscle cell lineages. Recent studies have shown that MyoD1 and myogenin also trans-activate expression of a number of cotransfected contractile protein genes, suggesting that these muscle regulatory factors are involved in controlling terminal differentiation events. The extent and specificity of trans activation by the muscle regulatory factors, however, have not been compared directly. In this study, we found that MyoD1, myogenin, and MRF4 exhibited different trans-activation capacities. In contrast to MyoD1 and myogenin, MRF4 was inefficient in trans-activating most of the genes tested, although conversion of C3H10T1/2 fibroblasts to a myogenic lineage was observed at similar frequencies with all three factors. Addition of basic fibroblast growth factor to cells expressing exogenous muscle regulatory factors inhibited the transcriptional activation of cotransfected genes, demonstrating that MyoD1, myogenin, or MRF4 proteins alone are not sufficient to produce a terminally differentiated phenotype. In all cases, trans activation was dependent on signal transduction pathways that are regulated by fibroblast growth factor. Our observations, coupled with previous studies showing differences in the temporal expression and protein structure of MyoD1, myogenin, and MRF4, suggest that the individual members of the muscle regulatory factor family have distinct biological roles in controlling skeletal muscle development.

Intellectual Virtues in Higher Education

2021 ◽  
Author(s):  
Ashley Floyd Kuntz ◽  
Rebecca M. Taylor
Keyword(s):  
Higher Education ◽  
Emerging Adults ◽  
Empirical Studies ◽  
Interdisciplinary Approach ◽  
Colleges And Universities ◽  
Vital Role ◽  
Intellectual Virtues ◽  
Cognitive Limitations ◽  
Intellectual Autonomy ◽  
The Individual

Intellectual virtues are characteristics that motivate individuals to pursue knowledge and understanding. They support the intellectual flourishing of the individual and consequently of society writ large. Scholars are only beginning to examine how these virtues are developed. An interdisciplinary approach that bridges philosophy, psychology, neuroscience, and education research is needed to add empirical grounding to philosophical conceptions of intellectual virtues and to provide recommendations for educators to advance these virtues. Schools arguably have a vital role to play in the development of the intellectual virtues. Colleges and universities embrace several core aims, among them fostering the individual flourishing of their students and the broader public good. Interpreted through a philosophical lens, achieving these aims invokes intellectual virtues. Two intellectual virtues—intellectual autonomy and intellectual fairness—are particularly salient for emerging adults in the higher education context. Empirical research has the potential to shed light on how these virtues are developed and what educators can do to better promote them. Although empirical studies suggest that emerging adults in college may be developmentally primed for the virtues of intellectual autonomy and intellectual fairness, many emerging adults do not leave college reliably demonstrating these virtues. Colleges and universities can do more to support their development by (a) providing students with challenging situations and supportive conditions, (b) creating opportunities for self-directed learning and intellectual risk-taking, and (c) raising awareness of cognitive limitations that undermine fairness.

Systematization Education Discussion and Application Research of Architecture Major in Higher Education

2011 ◽  
Vol 88-89 ◽  
pp. 759-762
Author(s):  
Bin Wang ◽  
Xia Zhao ◽  
Xiao Wen Bian ◽  
Jian Guo Li ◽  
Zhao Jun Ren ◽  
...  
Keyword(s):  
Higher Education ◽  
Real Estate ◽  
High Speed ◽  
Colleges And Universities ◽  
Application Research ◽  
Professional Skill ◽  
Industry Development ◽  
Business Establishment ◽  
Pillar Industry ◽  
Education Platform

In the industry division standard GB/T 4754-2002, construction includes two types. They are E- construction and K-construction, especially the booming real estate has been the first pillar industry in recent years. The industry development provide capacious space for the talents that express in the enrollment amount of colleges and universities and the incrementary ratio is 20% higher than other traditional professions. As the important education combination of architecture professional ability, people with professional skill needs to grasp opportunity of high-speed development to adjust the industry requirement. That will train students to reach professionalization, specialization and pay attention to the talents training systematization that students can express their innovation and business establishment in the architecture industry. This article will emphasize in the systematization education mode and application of architecture major in higher education, describe the establishment of projectization education platform, sectional type education application and courses resource accumulate and integration then to provide new opinion and method to the higher education revolution.

scholarly journals Physiological Requirement for Both SH2 Domains for Phospholipase C-γ1 Function and Interaction with Platelet-Derived Growth Factor Receptors

1999 ◽  
Vol 19 (7) ◽  
pp. 4961-4970 ◽  
Author(s):  
Qun-sheng Ji ◽  
Ansuman Chattopadhyay ◽  
Manuela Vecchi ◽  
Graham Carpenter
Keyword(s):  
Growth Factor ◽  
Phospholipase C ◽  
Intact Cell ◽  
Biological Response ◽  
Sh2 Domain ◽  
Site Directed Mutagenesis ◽  
Platelet Derived Growth Factor ◽  
Surface Plasmon Resonance Analysis ◽  
Sh2 Domains ◽  
The Individual

ABSTRACT Two approaches have been utilized to investigate the role of individual SH2 domains in growth factor activation of phospholipase C-γ1 (PLC-γ1). Surface plasmon resonance analysis indicates that the individual N-SH2 and C-SH2 domains are able to specifically recognize a phosphotyrosine-containing peptide corresponding to Tyr 1021 of the platelet-derived growth factor (PDGF) β receptor. To assess SH2 function in the context of the full-length PLC-γ1 molecule as well as within the intact cell, PLC-γ1 SH2 domain mutants, disabled by site-directed mutagenesis of the N-SH2 and/or C-SH2 domain(s), were expressed in Plcg1−/− fibroblasts. Under equilibrium incubation conditions (4°C, 40 min), the N-SH2 domain, but not the C-SH2 domain, was sufficient to mediate significant PLC-γ1 association with the activated PDGF receptor and PLC-γ1 tyrosine phosphorylation. When both SH2 domains in PLC-γ1 were disabled, the double mutant did not associate with activated PDGF receptors and was not tyrosine phosphorylated. However, no single SH2 mutant was able to mediate growth factor activation of Ca2+mobilization or inositol 1,4,5-trisphosphate (IP3) formation. Subsequent kinetic experiments demonstrated that each single SH2 domain mutant was significantly impaired in its capacity to mediate rapid association with activated PDGF receptors and become tyrosine phosphorylated. Hence, when assayed under physiological conditions necessary to achieve a rapid biological response (Ca2+mobilization and IP3 formation), both SH2 domains of PLC-γ1 are essential to growth factor responsiveness.

scholarly journals Identification of Novel Interaction Sites that Determine Specificity between Fibroblast Growth Factor Homologous Factors and Voltage-gated Sodium Channels

2011 ◽  
Vol 286 (27) ◽  
pp. 24253-24263 ◽  
Author(s):  
Chaojian Wang ◽  
Chuan Wang ◽  
Ethan G. Hoch ◽  
Geoffrey S. Pitt
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Sodium Channels ◽  
Fibroblast Growth ◽  
Subcellular Targeting ◽  
Voltage Gated ◽  
Interaction Sites ◽  
Voltage Gated Sodium Channels ◽  
C Terminus ◽  
The Individual

Fibroblast growth factor homologous factors (FHFs, FGF11–14) bind to the C termini (CTs) of specific voltage-gated sodium channels (VGSC) and thereby regulate their function. The effect of an individual FHF on a specific VGSC varies greatly depending upon the individual FHF isoform. How individual FHFs impart distinctive effects on specific VGSCs is not known and the specificity of these pairwise interactions is not understood. Using several biochemical approaches combined with functional analysis, we mapped the interaction site for FGF12B on the NaV1.5 C terminus and discovered previously unknown determinants necessary for FGF12 interaction. Also, we demonstrated that FGF12B binds to some, but not all NaV1 CTs, suggesting specificity of interaction. Exploiting a human single nucleotide polymorphism in the core domain of FGF12 (P149Q), we identified a surface proline that contributes a part of this pairwise specificity. This proline is conserved among all FHFs, and mutation of the homologous residue in FGF13 also leads to loss of interaction with a specific VGSC CT (NaV1.1) and loss of modulation of the resultant Na+ channel function. We hypothesized that some of the specificity mediated by this proline may result from differences in the affinity of the binding partners. Consistent with this hypothesis, surface plasmon resonance data showed that the P149Q mutation decreased the binding affinity between FHFs and VGSC CTs. Moreover, immunocytochemistry revealed that the mutation prevented proper subcellular targeting of FGF12 to the axon initial segment in neurons. Together, these results give new insights into details of the interactions between FHFs and NaV1.x CTs, and the consequent regulation of Na+ channels.

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