Effect of Supplementary Branch Chain Amino Acids on the Ability of Table Tennis Players by Image Analysis of Visual Sensors

The purpose of this article is to in-depth explore the specific effects of supplementation of branched-chain amino acids on table tennis performance and its mechanism. Athletic ability refers to the ability of a person to participate in sports and training. It is a comprehensive manifestation of a person’s physical form, quality, function, skills, and psychological abilities. From a biochemical point of view, the level of exercise capacity mainly depends on the energy supply, transfer, and utilization of energy during exercise. The metabolic basis of exercise capacity and its influencing factors, the central and peripheral causes of sports fatigue, and the general law of the recovery of consumed substances after exercise provide a theoretical basis for athletes’ selection of talents, evaluation of training effects, and formulation of training plans. The main function of the vision sensor is to obtain enough of the most primitive images to be processed by the machine vision system. Use the latest vision sensor technology for in-depth research. This article takes 20 professional table tennis players with the same sports score as the research object and divides the athletes into the control group and observation group supplemented with branch chain amino acids. For the observation group, the exercise plan is to design two one-hour table tennis games, divided into two days, with a 10-minute break after half an hour of the game, and the athletes in the observation group to have a weight of 0.3 g/kg before and during the rest of the game. Weight measurement supplemented with branched-chain amino acids, the control group, athletes supplemented with the same amount of ordinary mineral water, the athletes’ fatigue index, endurance index, and reaction ability index were scored, and the athlete’s blood was drawn to test the sports-related biochemical indicators after the end of table tennis. The results of the study showed that after supplementation with branched-chain amino acids, the fatigue index of the athletes in the observation group was ( 7.5 ± 1.2 ), the fatigue index of the control group was ( 11.2 ± 1.5 ), the endurance index of the observation group was ( 28.4 ± 4.8 ), that of the control group was ( 19.6 ± 3.7 ), the reaction ability index of the observation group was ( 18.4 ± 4.2 ), and the control group was ( 12.3 ± 2.8 ). At the same time, the athletes’ plasma antioxidant capacity and metabolism level of the observation group were significantly higher than those of the control group. Therefore, it can be seen that supplementing branched-chain amino acids can effectively improve the athletic ability of table tennis players.

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Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial

Clinical Chemistry ◽

10.1373/clinchem.2015.251710 ◽

2016 ◽

Vol 62 (4) ◽

pp. 582-592 ◽

Cited By ~ 91

Author(s):

Miguel Ruiz-Canela ◽

Estefania Toledo ◽

Clary B Clish ◽

Adela Hruby ◽

Liming Liang ◽

...

Keyword(s):

Cardiovascular Disease ◽

Amino Acids ◽

Cardiovascular Death ◽

Branched Chain Amino Acids ◽

Control Group ◽

Cvd Risk ◽

Hazard Ratios ◽

Increased Risk ◽

Branched Chain

Abstract BACKGROUND The role of branched-chain amino acids (BCAAs) in cardiovascular disease (CVD) remains poorly understood. We hypothesized that baseline BCAA concentrations predict future risk of CVD and that a Mediterranean diet (MedDiet) intervention may counteract this effect. METHODS We developed a case-cohort study within the Prevención con Dieta Mediterránea (PREDIMED), with 226 incident CVD cases and 744 noncases. We used LC-MS/MS to measure plasma BCAAs (leucine, isoleucine, and valine), both at baseline and after 1 year of follow-up. The primary outcome was a composite of incident stroke, myocardial infarction, or cardiovascular death. RESULTS After adjustment for potential confounders, baseline leucine and isoleucine concentrations were associated with higher CVD risk: the hazard ratios (HRs) for the highest vs lowest quartile were 1.70 (95% CI, 1.05–2.76) and 2.09 (1.27–3.44), respectively. Stronger associations were found for stroke. For both CVD and stroke, we found higher HRs across successive quartiles of BCAAs in the control group than in the MedDiet groups. With stroke as the outcome, a significant interaction (P = 0.009) between baseline BCAA score and intervention with MedDiet was observed. No significant effect of the intervention on 1-year changes in BCAAs or any association between 1-year changes in BCAAs and CVD were observed. CONCLUSIONS Higher concentrations of baseline BCAAs were associated with increased risk of CVD, especially stroke, in a high cardiovascular risk population. A Mediterranean-style diet had a negligible effect on 1-year changes in BCAAs, but it may counteract the harmful effects of BCAAs on stroke.

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Branched-Chain Amino Acids Have Equivalent Effects to Other Essential Amino Acids on Lifespan and Aging-Related Traits in Drosophila

The Journals of Gerontology Series A ◽

10.1093/gerona/glz080 ◽

2019 ◽

Vol 75 (1) ◽

pp. 24-31 ◽

Cited By ~ 10

Author(s):

Paula Juricic ◽

Sebastian Grönke ◽

Linda Partridge

Keyword(s):

Amino Acids ◽

Control Diet ◽

Essential Amino Acids ◽

Branched Chain Amino Acids ◽

Control Group ◽

Dependent Manner ◽

Dietary Nitrogen ◽

Compensatory Feeding ◽

Age Related ◽

Branched Chain

Abstract Branched-chain amino acids (BCAAs) have been suggested to be particularly potent activators of Target of Rapamycin (TOR) signaling. Moreover, increased circulating BCAAs are associated with higher risk of insulin resistance and diabetes in both mice and humans, and with increased mortality in mice. However, it remains unknown if BCAAs play a more prominent role in longevity than do other essential amino acids (EAAs). To test for a more prominent role of BCAAs in lifespan and related traits in Drosophila, we restricted either BCAAs or a control group of three other EAAs, threonine, histidine and lysine (THK). BCAA restriction induced compensatory feeding, lipid accumulation, stress resistance and amelioration of age-related gut pathology. It also extended lifespan in a dietary-nitrogen-dependent manner. Importantly, the control restriction of THK had similar effects on these phenotypes. Our control diet was designed to have every EAA equally limiting for growth and reproduction, and our findings therefore suggest that the level of the most limiting EAAs in the diet, rather than the specific EAAs that are limiting, determines the response of these phenotypes to EAA restriction.

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Thirteen-Week Oral Toxicity Study of Branched-Chain Amino Acids in Rats

International Journal of Toxicology ◽

10.1080/10915810490444424 ◽

2004 ◽

Vol 23 (2) ◽

pp. 119-126 ◽

Cited By ~ 25

Author(s):

Shoji Tsubuku ◽

Kazuhisa Hatayama ◽

Toyohisa Katsumata ◽

Nobuo Nishimura ◽

Kazunori Mawatari ◽

...

Keyword(s):

Amino Acids ◽

Body Weight ◽

Ketone Bodies ◽

Body Weight Gain ◽

Recovery Period ◽

Branched Chain Amino Acids ◽

Control Group ◽

Standard Diet ◽

Oral Toxicity ◽

Branched Chain

Branched-chain amino acids (l-isoleucine, l-valine, and l-leucine) are being increasingly used in sport supplements. This study evaluated toxicological and behavioral effects of l-isoleucine (Ile), l-valine (Val), and l-leucine (Leu) during a dosing study with male and female Sprague-Dawley rats. The amino acids were incorporated into a standard diet at doses equal to 1.25%, 2.5%, and 5.0% ( w/ w). A control group of rats received a standard diet. All diets were administered ad libitum for 13 consecutive weeks. To examine stability of any potential effects, the administration period was followed by a 5-week recovery period, during which only the standard diet was provided to all animals. No significant, dose-related effects on body weight were found in rats fed a Leu-and Ile-supplemented diet. Val mixed into a diet at 5.0% ( w/ w) decreased slightly, but significantly body weight gain in females, but not males. Ile (5.0% w/ w) affected the urine electrolytes, protein, ketone bodies, urine glucose, and urobilinogen in both genders, yet the observed changes remained mostly within the range observed in controls. The random findings in hepatology and ophthalmology at the 13-week sacrifice were not considered toxicologically relevant to effects of the tested amino acids. No significant changes in organ weights were recorded. We estimate the no-observed-adverse-effect level (NOAEL) for Ile at 2.5% for both genders (male, 1.565 ± 0.060 g/kg/day; females, 1.646 ± 0.095 g/kg/day), Val at 5.0% for males (3.225 ± 0.135 g/kg/day) and 2.5% for females (1.853 ± 0.060 g/kg/day), and Leu at 5.0% for both genders (males, 3.333 ± 0.101 g/kg/day: females, 3.835 ± 0.257 g/kg/day).

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Effect of Lifestyle Intervention in the Concentration of Adipoquines and Branched Chain Amino Acids in Subjects with High Risk of Developing Type 2 Diabetes: Feel4Diabetes Study

Cells ◽

10.3390/cells9030693 ◽

2020 ◽

Vol 9 (3) ◽

pp. 693

Author(s):

Itziar Lamiquiz-Moneo ◽

Ana M. Bea ◽

Cristian Palacios-Pérez ◽

Pilar De Miguel-Etayo ◽

Esther M. González-Gil ◽

...

Keyword(s):

Type 2 Diabetes ◽

Amino Acids ◽

High Risk ◽

Glycated Hemoglobin ◽

Intervention Group ◽

Branched Chain Amino Acids ◽

Control Group ◽

Community Based ◽

Branched Chain

Introduction: The global prevalence of type 2 diabetes (T2D) is increasing rapidly, especially in low- and middle-income countries and has a high number of associated comorbidities. Plasmatic concentrations of branched chain amino acids (BCAA) and retinol-binding protein 4 (RBP4) have been shown to be elevated in T2D subjects in cross-sectional studies. However, the effect of lifestyle community-based interventions on BCAA and RBP4 concentrations has not yet been analyzed. Material and methods: The Feel4Diabetes study is a school and community-based intervention that identified 360 European families with a high risk of developing T2D according to the FINDRISC questionnaire. Families were randomized in control and intervention groups were followed-up from 2016 to 2018. In the Spanish families, the concentration of BCAA and RBP4 was determined in 266 subjects (115 control and 151 intervention group) that attended the three time-point assessments by colorimetric and ELISA reaction, respectively. Results: Baseline BCAA levels showed positive correlations with the FINDRISC score and glucose impairment (baseline glucose, insulin, and glycated hemoglobin), body mass index, and body weight. The participants receiving the community-based intervention showed a significant decrease in glycated hemoglobin and BCAA levels compared to the control group (p = 0.011 and p < 0.001, respectively). However, baseline RBP4 did not show significant correlations with anthropometric and glycemic parameters, and no significant change was observed in anthropometric parameters and RBP4 concentrations throughout the follow-up. Conclusion: A community-based intervention on lifestyle led to a significant reduction in BCAA levels regardless of weight loss. These findings suggest that this interventional approach could be promising in T2D prevention.

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Only L-valine among branched-chain amino acids is effective in promoting the growth of the small intestinal mucosa

Gastroenterology ◽

10.1016/s0016-5085(01)83364-3 ◽

2001 ◽

Vol 120 (5) ◽

pp. A676-A676

Author(s):

T TAKAHASHI ◽

H DOI ◽

H KOMATSU ◽

K SATO ◽

O UEDA ◽

...

Keyword(s):

Amino Acids ◽

Intestinal Mucosa ◽

Branched Chain Amino Acids ◽

Small Intestinal Mucosa ◽

Small Intestinal ◽

Branched Chain

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The Weight Loss Effects of Branched Chain Amino Acids and Vitamin B6: A Randomized Controlled Trial on Obese and Overweight Women

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000511 ◽

2018 ◽

Vol 88 (1-2) ◽

pp. 80-89 ◽

Cited By ~ 3

Author(s):

Zahra Shakibay Novin ◽

Saeed Ghavamzadeh ◽

Alireza Mehdizadeh

Keyword(s):

Amino Acids ◽

Weight Loss ◽

Body Composition ◽

Vitamin B6 ◽

Controlled Trial ◽

Density Lipoprotein ◽

Branched Chain Amino Acids ◽

Model Assessment ◽

Waist To Hip Ratio ◽

Branched Chain

Abstract. Branched chain amino acids (BCAA), with vitamin B6 have been reported to improve fat metabolism and muscle synthesis. We hypothesized that supplementation with BCAA and vitamin B6 would result in more weight loss and improve body composition and blood markers related to cardiovascular diseases. Our aim was to determine whether the mentioned supplementation would affect weight loss, body composition, and cardiovascular risk factors during weight loss intervention. To this end, we performed a placebo-controlled randomized clinical trial in 42 overweight and obese women (BMI = 25–34.9 kg/m2). Taking a four-week moderate deficit calorie diet (–500 kcal/day), participants were randomized to receive BCAA (6 g/day) with vitamin B6 (40 mg/day) or placebo. Body composition variables measured with the use of bioelectrical impedance analysis, homeostatic model assessment, and plasma insulin, Low density lipoprotein, High density lipoprotein, Total Cholesterol, Triglyceride, and fasting blood sugar were measured. The result indicated that, weight loss was not significantly affected by BCAA and vitamin B6 supplementation (–2.43 ± 1.02 kg) or placebo (–1.64 ± 1.48 kg). However, significant time × treatment interactions in waist to hip ratio (P = 0.005), left leg lean (P = 0.004) and right leg lean (P = 0.023) were observed. Overall, supplementation with BCAA and vitamin B6 could preserve legs lean and also attenuated waist to hip ratio.

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