scholarly journals Infected Facial Tissue Fillers Caused by Dental Infection

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Antoine Berberi ◽  
Bouchra Hjeij ◽  
Georges Aad ◽  
Georges Aoun
Keyword(s):  
Female Patient ◽  
Dental Treatment ◽  
Complete Healing ◽  
Facial Rejuvenation ◽  
Dermal Filler ◽  
Volume Loss ◽  
Dental Infection ◽  
Dermal Fillers ◽  
Facial Contours ◽  
Radiological Examinations

Injectable dermal fillers are widely used for facial rejuvenation; they help reshape the facial contours by treating volume loss due to aging changes. Facial fillers may become infected following a dental infection. In this report, we present a case of a 44-year-old female patient who presented with a swelling in her upper right buccal region following dental treatment of her second maxillary right premolar. After a thorough history, clinical, and radiological examinations, the diagnosis of infected dermal filler was made. The lesion was treated by association of two antibiotics (ciprofloxacin IM and clindamycin tablets 300 mg), and a complete healing was observed two months after the end of the dental treatments.

scholarly journals Dermal Filler types, Effect on soft tissue and Life Style correlation

2020 ◽  
Vol 3 ◽  
pp. 1
Author(s):  
Dalia A Mohamed
Keyword(s):  
Hyaluronic Acid ◽  
Soft Tissue ◽  
Life Style ◽  
Dermal Filler ◽  
Dermal Fillers ◽  
Bovine Collagen ◽  
The World ◽  
History Of ◽  
Facial Contours ◽  
Common Manifestation

One of the most common manifestation in our time, especially among girls, is those procedures on the skin or maintaining or to modify some of the changes in the skin, such as those that come due to aging or any other cosmetic reasons. Fillers and Botox are two of the most popular procedures. Dermal fillers are effective treatments used to soften and reduce wrinkles and deep lines, fill out the cheeks and smooth facial contours. There are four main types of injectable dermal fillers, including fat, collagen, hyaluronic acid, and microsphere-containing carriers of another material such as polymethyl methacrylate (PMMA). So that to understand any type of injection, it is important to look at its history for valuable lessons and for successful progress. Honestly, it is very interesting to see what and where the world gets in the last 40 years of injectable. Today, we will be examining the brief history of dermal fillers from their bovine collagen roots, to the advanced fillers that are available today. In this review, we aimed to show some types of dermal fillers including a variety of its complication in soft tissue. Also, we try to correlate the factor of lifestyle  with its variant effects.

scholarly journals Toward Physicochemical and Rheological Characterization of Different Injectable Hyaluronic Acid Dermal Fillers Cross-Linked with Polyethylene Glycol Diglycidyl Ether

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 948
Author(s):  
Nicola Zerbinati ◽  
Sabrina Sommatis ◽  
Cristina Maccario ◽  
Maria Chiara Capillo ◽  
Giulia Grimaldi ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Polyethylene Glycol ◽  
Biological Activities ◽  
Diglycidyl Ether ◽  
Dermal Filler ◽  
Cross Linking ◽  
Matrix Structure ◽  
Dermal Fillers ◽  
Rheological Characterization

(1) Background: Injectable hyaluronic acid (HA) dermal fillers are used to restore volume, hydration and skin tone in aesthetic medicine. HA fillers differ from each other due to their cross-linking technologies, with the aim to increase mechanical and biological activities. One of the most recent and promising cross-linkers is polyethylene glycol diglycidyl ether (PEGDE), used by the company Matex Lab S.p.A., (Brindisi, Italy) to create the HA dermal filler PEGDE family. Over the last few years, several studies have been performed to investigate the biocompatibility and biodegradability of these formulations, but little information is available regarding their matrix structure, rheological and physicochemical properties related to their cross-linking technologies, the HA content or the degree of cross-linking. (2) Methods: Seven different injectable HA hydrogels were subjected to optical microscopic examination, cohesivity evaluation and rheological characterization in order to investigate their behavior. (3) Results: The analyzed cross-linked dermal fillers showed a fibrous “spiderweb-like” matrix structure, with each medical device presenting different and peculiar rheological features. Except for HA non cross-linked hydrogel 18 mg/mL, all showed an elastic and cohesive profile. (4) Conclusions: The comparative analysis with other literature works makes a preliminary characterization of these injectable medical devices possible.

scholarly journals Facial Rejuvenation with Concentrated Lipograft—A 12 Month Follow-Up Study

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 594
Author(s):  
Lukas Prantl ◽  
Eva Brix ◽  
Sally Kempa ◽  
Oliver Felthaus ◽  
Andreas Eigenberger ◽  
...  
Keyword(s):  
Stromal Vascular Fraction ◽  
Facial Rejuvenation ◽  
Fat Graft ◽  
Volume Loss ◽  
Patient’S Satisfaction ◽  
Resazurin Assay ◽  
Long Term Follow Up ◽  
The Difference

Lipofilling is a popular technique to treat volume loss in aging patients. The isolated adipose tissue is composed of adipocytes and stromal vascular fraction cells, which include adipose-derived stem cells (ASC). We hypothesize that the patient’s wrinkle severity scale (WSS) and patient’s satisfaction on the global aesthetic improvement scale (GAIS) can be improved after using concentrated lipoaspirate. Fourteen patients (54 years ± 11.09 years) with volume loss in the midface area underwent waterjet-assisted liposuction (Human Med AG, Schwerin, Germany). Fat was centrifuged in an ACP Double Syringe (Arthrex GmbH, Munich, Germany) using Rotofix 32A centrifuge (Andreas Hettich, GmbH & Co.KG, Tuttlingen, Germany). Homogenization was performed using the double syringe and a 1.4 mm female–female luerlock connector. After a second centrifugation, patients received periorbital (PO) and nasolabial (NL) lipografting. ASC count was performed after enzymatical digestion. Vitality of cells was assessed using a resazurin assay. During long-term follow up (12 months, n = 10), we found a high patient’s satisfaction (GAIS 1+/−0.52) and a good improvement of the WSS during short- and long-term follow-up. The ASC count of processed lipoaspirate was 2.1-fold higher than of unprocessed lipoaspirate (p < 0.001). The difference of ASC in sedimented and simply centrifuged lipoaspirate was also significant (p < 0.05). Facial rejuvenation with concentrated fat graft offers good results concerning objective aesthetic outcome and patient’s satisfaction.

Anatomical Variations in the Course of Labial Arteries: A Literature Review

2018 ◽  
Vol 39 (11) ◽  
pp. 1225-1235 ◽  
Author(s):  
Souphiyeh Samizadeh ◽  
Ali Pirayesh ◽  
Dario Bertossi
Keyword(s):  
Literature Review ◽  
Anatomical Variation ◽  
Anatomical Variations ◽  
Great Variability ◽  
Dermal Filler ◽  
Functional Importance ◽  
Dermal Fillers ◽  
Cutaneous Necrosis ◽  
Complex Anatomy ◽  
Vascular Compromise

AbstractBackgroundNonsurgical lip enhancement using dermal fillers is a very popular procedure. The trend for enlarged lips has been popularized by media and social media. The lips have considerable aesthetic and functional importance, in addition to having a complex anatomy. Serious complications, including vascular compromise or occlusion leading to cutaneous necrosis and blindness, can occur as the result of lip enhancement using dermal fillers. Therefore, aesthetic practitioners require an in-depth understanding of the anatomy and vasculature of the lips and the perioral area prior to providing lip enhancement using dermal fillers.ObjectivesThis literature review aimed to summarize existing data describing the origin, path, and depth of the superior and inferior labial arteries, and to help aesthetic practitioners in providing safer injections to the lips.MethodsA literature search was carried out to summarize the available data describing the origin, path, and depth of the labial arteries.ResultsAnalysis of the literature revealed that the labial arteries display great variability with respect to path (distribution), presence, and location.ConclusionsIncreasing the volume of lips through injections of dermal filler needs to be undertaken with caution, and awareness of the anatomical variation in artery location and path is a crucial concept that is essential when injecting the lips.

Adjuncts to Facial Rejuvenation

2020 ◽  
Author(s):  
Heather R. Faulkner
Keyword(s):  
Soft Tissue ◽  
Facial Rejuvenation ◽  
Dermal Filler ◽  
Nasolabial Fold ◽  
High Quality ◽  
The Past ◽  
Appropriate Treatment ◽  
Soft Tissue Filler ◽  
Facial Anatomy ◽  
Filler Complications

The preferred methods for facial rejuvenation have been changing over the past decade, with operative procedures on the decline and minimally invasive, office-based procedures on the rise. As a result, it is critical for plastic surgery practitioners to understand the intricacies of the use of neuromodulators and soft tissue fillers in this milieu. While these procedures are usually performed in an office, without general anesthesia, the risk of significant complications still exists. The knowledge of facial anatomy, techniques, and pitfalls is essential for achieving high quality, predictable, and reproducible results. Likewise, when a complication arises, prompt recognition and appropriate treatment is paramount. In this chapter, the history, purpose, technical guidelines, and complications of adjunctive techniques for facial rejuvenation are reviewed in detail. This review contains 2 tables, and 52 references. Keywords: facial rejuvenation, neuromodulator, soft tissue filler, botulinum toxin, dermal filler, aging face, facial rhytids, filler complications, glabellar lines, nasolabial fold 

scholarly journals Cetuximab associated dermal filler reaction

2019 ◽  
Vol 12 (8) ◽  
pp. e228882 ◽  
Author(s):  
Shivanshan Pathmanathan ◽  
Marcin Dzienis
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Radiation Therapy ◽  
Hyaluronic Acid ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Dermal Filler ◽  
Dermal Fillers ◽  
Epidermal Growth ◽  
Receptor Inhibitor

A 52-year-old male patient with hyaluronic acid-based dermal fillers injected in his cheeks was diagnosed with glossotonsillary malignancy, and managed with concurrent cetuximab (epidermal growth factor receptor inhibitor) and radiation therapy. He developed significant inflammation around the dermal filler sites after first cycle of cetuximab which improved with dissolution of the dermal fillers with hyaluronidase. This suggests that cetuximab can lead to inflammation around the dermal filler sites, which can be treated with dissolution of the filler.

Dermal filler migration complications following lip augmentation procedures

2020 ◽  
Vol 9 (7) ◽  
pp. 276-281
Author(s):  
Danielle Davy
Keyword(s):  
Hyaluronic Acid ◽  
Rare Complication ◽  
Post Treatment ◽  
The Body ◽  
Dermal Filler ◽  
Dermal Fillers ◽  
Short Term ◽  
Lip Augmentation ◽  
Permanent Fillers

Filler migration is a rare complication of dermal filler treatment. Although most research has found that more permanent fillers, such as silicone, are more likely to migrate due to their long-term presence in the body, there have also been reported cases of filler migration from short-term hyaluronic acid-based dermal fillers. As lip augmentation procedures are fast becoming one of the most frequently requested treatments in medical aesthetics, this article looks at the longevity of hyaluronic acid lip dermal fillers, while also aiming to assess the cause of dermal filler post-treatment migration and evaluating how to minimise its risk.

scholarly journals HA-based dermal filler: downstream process comparison, impurity quantitation by validated HPLC-MS analysis, and in vivo residence time study

2019 ◽  
Vol 17 (3) ◽  
pp. 228080001986707 ◽  
Author(s):  
Cristian Guarise ◽  
Carlo Barbera ◽  
Mauro Pavan ◽  
Susi Panfilo ◽  
Riccardo Beninatto ◽  
...  
Keyword(s):  
Residence Time ◽  
Rabbit Model ◽  
Diglycidyl Ether ◽  
In Vitro Cytotoxicity ◽  
Dermal Filler ◽  
Dermal Fillers ◽  
Process Comparison ◽  
Hygroscopic Properties

The success of hyaluronic acid (HA)-based dermal fillers, with more than 2 million minimally invasive procedures conducted in 2016 in the US alone, is due to their hygroscopic properties of biocompatibility and reversibility. The type and density of HA cross-linkage, as well as the manufacturing technology, may influence not only the in vivo persistence but also the safety profile of dermal fillers. 1,4-Butanediol diglycidyl ether (BDDE) is the cross-linker used in most market-leading HA fillers; 1,4-butanediol di-(propan-2,3-diolyl) ether (BDPE) is the major impurity obtained from the HA–BDDE cross-linking (HBC) process. In this work, a new process to obtain high purity HBC fillers was developed. A new HPLC-MS method was validated for the quantification of BDPE content in HBC dermal fillers. In vitro cytotoxicity of BDPE was evaluated in fibroblasts (IC50 = 0.48 mg/mL). The viscoelasticity was monitored during the shelf-life of the HBC-10% hydrogel and was correlated with in vitro hyaluronidase resistance and in vivo residence time in a rabbit model. This analysis showed that elasticity is the best parameter to predict the in vivo residence time. Finally, a series of parameters were investigated in certain marketed dermal fillers and were compared with the results of the HBC-10% hydrogel.

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