scholarly journals Ruptured Retinal Arterial Macroaneurysm Secondary to Toxoplasmic Kyrieleis Arteriolitis: A Case Report

2017 ◽  
Vol 8 (2) ◽  
pp. 390-395
Author(s):  
Natalie Huang ◽  
W. Andrew Lee ◽  
Sean Rivera ◽  
Sandra R. Montezuma
Keyword(s):  
Fundus Photography ◽  
Systemic Hypertension ◽  
Hypertensive Retinopathy ◽  
Eye Color ◽  
Retinal Arterial Macroaneurysm ◽  
Vein Occlusion ◽  
Ocular Imaging ◽  
History Of ◽  
The Right

Purpose: The aim of this report was to describe multimodal ocular imaging findings in a patient who presented with a ruptured retinal arterial macroaneurysm (RAM) associated with toxoplasmic Kyrieleis arteriolitis. Methods: We report the case of a 64-year-old man with a history of systemic hypertension and dense amblyopia of the left eye who presented with decreased vision and new floaters in the left eye. Color fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, and indocyanine green angiography were used as diagnostic imaging tools. Results: No signs of hypertensive retinopathy were noted in the right eye. Multiple chorioretinal scars characteristic of previous toxoplasmosis were revealed in the left eye, with one covering most of the macula. Periarterial plaques or Kyrieleis arteriolitis were observed in retinal arteries surrounding the toxoplasmic retinal scars. Multiple RAMs were observed in these vessels, one of which was acutely ruptured. A perivenular plaque associated with a chronic branch retinal vein occlusion (BRVO) was noted along the same arcade at the arteriovenous crossing. Conclusion: RAM formation and BRVO can present as possible long-term complications of toxoplasmic Kyrieleis arteriolitis. This is the first reported case demonstrating an association between toxoplasmic Kyrieleis arteriolitis and RAM formation.

scholarly journals Oncocytic cyst of the larynx: a rare finding

2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-227214 ◽  
Author(s):  
Samantha Baird ◽  
Halina Mann ◽  
Cesar M Salinas-La Rosa ◽  
Halil Ozdemir
Keyword(s):  
Social History ◽  
Granular Eosinophilic Cytoplasm ◽  
Eosinophilic Cytoplasm ◽  
Long Term Follow Up ◽  
History Of ◽  
The Right ◽  
False Vocal ◽  
Columnar Cells

A 75-year-old woman presented with an 18-month history of severe, slowly worsening dysphonia. She was a smoker and known to have multiple benign cystic thyroid lesions. She reported no associated symptoms and other medical and social history was unremarkable. Fibreoptic nasendoscopy revealed a right-sided supraglottic cyst appearing to arise from the right false vocal cord. Further bedside examination was unremarkable. She underwent microlaryngoscopy and biopsy which showed a cyst originating from the right anterior ventricle, successfully removed without rupture using cold steel. Formal histopathology revealed a 14×10×7 mm unilocular, completely excised cyst lined by oncocytic epithelium and composed of columnar cells with darkly stained nuclei and abundant granular, eosinophilic cytoplasm. Three weeks postoperatively the patient’s voice had returned to normal. To date, 11 months postoperatively, there is no evidence of recurrence, and she will continue long-term follow-up.

scholarly journals Thirteen-year follow-up of parasellar intravascular papillary endothelial hyperplasia successfully treated by surgical excision: case report

2015 ◽  
Vol 15 (4) ◽  
pp. 384-391 ◽  
Author(s):  
Sook Young Sim ◽  
Yong Cheol Lim ◽  
Keun Soo Won ◽  
Kyung Gi Cho
Keyword(s):  
Surgical Excision ◽  
Subtotal Resection ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Long Term Follow Up ◽  
History Of ◽  
Papillary Endothelial Hyperplasia ◽  
The Right ◽  
Frontal Skull Base

Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.

Hypertensive retinopathy in a neonate

2020 ◽  
Vol 13 (10) ◽  
pp. e235720
Author(s):  
Prakhar Goyal ◽  
Komal Agarwal
Keyword(s):  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Female Child ◽  
Visual Development ◽  
Fundus Photography ◽  
Systemic Hypertension ◽  
Hypertensive Retinopathy ◽  
Long Term Effects ◽  
Hard Exudates

A 23-day-old female child diagnosed as having systemic hypertensive emergency was referred for retinal screening. The fundus examination showed bilateral intraretinal haemorrhages and hard exudates especially at the macula. Venous looping was noted. The ocular features were suggestive of hypertensive retinopathy. Control of systemic hypertension was advised and was managed conservatively with close follow-up. Widefield fundus photography was done at presentation and follow-up to document the change in retinopathy with control of hypertension.The haemorrhages and exudates resolved on follow-up but significant retinal pigment epithelium changes with beaten bronze appearance were noted at the area of previous oedema. Presence of hypertensive retinopathy in a neonate is rare and has long-term effects on visual development. This report describes the course of hypertensive retinopathy in a neonate.

scholarly journals Acute blue finger syndrome: a rare benign cause of acute digit discolouration

2019 ◽  
Vol 12 (1) ◽  
pp. e223365
Author(s):  
Kiran Dhaliwal ◽  
Colin Thomas Brewster ◽  
Sivarajasingham Pakeerathan
Keyword(s):  
Rapid Assessment ◽  
Middle Finger ◽  
X Rays ◽  
Benign Condition ◽  
Volar Aspect ◽  
History Of ◽  
The Right ◽  
Digital Ischaemia ◽  
First Time

Acute blue finger syndrome is a rare benign condition that mimics digital ischaemia. We discuss the case of a 32-year-old woman who presented with a 6hour history of blue discolouration of the middle finger of the right hand, associated with pain and swelling. There was no history of trauma and this was the first time that the patient had experienced these symptoms. Examination found blue discolouration of the digit primarily on the volar aspect with associated swelling. All investigations, including blood tests, X-rays and Doppler scanning, were normal. The symptoms resolved spontaneously within 48 hours. There were no recurrent episodes or long-term sequelae. Patients presenting with an acutely blue finger need rapid assessment to exclude digit ischaemia. Knowledge of this rare benign condition may prevent unnecessary distress, invasive investigations and potentially harmful treatment of a healthy patient.

scholarly journals Isolated myxoid degeneration of aortic valve: diagnostic dilemma

2019 ◽  
Vol 12 (3) ◽  
pp. e228414
Author(s):  
Htay Htay Kyi ◽  
Kewan Hamid ◽  
Luay Alkotob ◽  
Thair Dawood
Keyword(s):  
Aortic Valve ◽  
Acute Pulmonary Oedema ◽  
Diagnostic Dilemma ◽  
Positron Emission ◽  
Valve Insufficiency ◽  
History Of ◽  
History Of Epilepsy ◽  
The Right ◽  
Myxoid Degeneration

Myxoid degeneration of the aortic valve as a cause of acute aortic valve regurgitation in young age is uncommon. We report a 39-year-old African-American man with a history of epilepsy and hypertension who presented with a 1-month history of worsening shortness of breath. He was diagnosed with acute pulmonary oedema. Transoesophageal echocardiogram showed normal ejection fraction but severe aortic valve insufficiency with small masses on the ventricular side of the right and non-coronary cusps, small vegetations cannot be ruled out but other valves were normal. Subsequent cultures were negative for endocarditis. Myocardial positron emission tomography (PET) scan was strongly suggestive of cardiac sarcoidosis. However, this diagnosis was ruled out as well when he underwent aortic valve replacement with bioprosthetic valve as he did not want to take long-term anticoagulation. Histological examination of the aortic valve showed myxoid degeneration. The patient was doing very well 1 year after the surgery.

Risk Factors for Branch and Central Retinal Vein Occlusion

2020 ◽  
pp. 115-120
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Risk Factors ◽  
Retinal Vein Occlusion ◽  
Open Angle Glaucoma ◽  
Case Control ◽  
Systemic Hypertension ◽  
Vein Occlusion ◽  
Increased Risk ◽  
History Of ◽  
Control Study ◽  
Central Retinal Vein

The Eye Disease Case-Control Study was a clinic-based, case-control study that investigated risk factors for 5 retinal diseases—branch retinal vein occlusion (BRVO), central retinal vein occlusion (CRVO), neovascular age-related macular degeneration (AMD), idiopathic macular hole, and rhegmatogenous retinal detachment—using a similar protocol and the same large pool of controls. An increased risk of BRVO was found in persons with a history of systemic hypertension, cardiovascular disease, increased body mass index at 20 years of age, a history of glaucoma, and higher serum levels of alpha 2 globulin. An increased risk of CRVO was found in persons with systemic hypertension, diabetes mellitus, and open-angle glaucoma. The authors recommended that patients with BRVO and CRVO should be evaluated for risk factors for cardiovascular disease (hypertension, hyperlipidemia, and diabetes), as well as for open-angle glaucoma.

scholarly journals Occurrence of metastatic eccrine porocarcinoma in an immunosuppressed patient

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mitul B. Modi ◽  
Ata S. Moshiri ◽  
Toru Shoji ◽  
Martin C. Mihm ◽  
Xiaowei Xu ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Immunosuppressive Therapy ◽  
Left Lung ◽  
Immunosuppressed Patient ◽  
Axillary Lymph ◽  
Comfort Care ◽  
History Of ◽  
The Right ◽  
Eccrine Porocarcinoma

Abstract Background Eccrine porocarcinoma is a rare malignancy accounting for 0.005 to 0.01% of all cutaneous tumors. However, its etiology is not well established. Herein we are reporting the occurrence of metastatic porocarcinoma of the back in a patient with a history of multiple cutaneous malignancies and chronic immunosuppression. Case presentation A 79-year-old male with a history of long-term immunosuppressive therapy for left lung transplantation and multiple cutaneous malignancies including melanoma, presented with an enlargening plaque on the right upper back. Biopsy demonstrated an infiltrative epithelial tumor with aggressive histology and ductal formation. Immunohistochemical stains for p63, CK-5/6, and CEA were diffusely positive, while CK-7 and CK-20 were negative. A diagnosis of eccrine porocarcinoma was made. He underwent complete wide excision with negative margins of the right upper back in January 2018. In November 2018, he was found to have a right posterior shoulder mass, positive right axillary lymph nodes, superficial right upper back soft tissue masses and lymphangitic carcinomatosis involving the left lung. He was transitioned to comfort care and subsequently passed from metastatic disease in December 2018. Conclusion The occurrence of eccrine porocarcinoma in a patient on long term immunosuppressive therapy for lung transplantation suggests a possible role for chronic immunosuppression in the induction of a subset of eccrine porocarcinomas, as in other cutaneous malignancies.

scholarly journals A Patient With Optic Nerve Pit Maculopathy Successfully Treated With Juxtapapillary Laser Photocoagulation

2021 ◽  
Author(s):  
Homayoun Nikkhah ◽  
Iman Ansari ◽  
Kiana Hassanpour
Keyword(s):  
Optic Nerve ◽  
Optic Disc ◽  
Laser Photocoagulation ◽  
Systemic Hypertension ◽  
Serous Macular Detachment ◽  
Abnormal Finding ◽  
Macular Detachment ◽  
History Of ◽  
Funduscopic Examination ◽  
The Right

Optic disc pits are rare and congenital or acquired anomalies of the optic disc, usually remaining asymptomatic. However, serous macular detachment or optic disc maculopathy is the most common complication, causing significant visual deterioration, without a current consensus about treatment. A 55-year-old woman with a past medical history of diabetes mellitus and systemic hypertension was referred for an abnormal finding in the retina. The Corrected Distance Visual Acuity (CDVA) was 20/40 in the right eye and 20/30 in the left eye. Marcus-Gunn was negative and Slit-lamp biomicroscopy revealed no pathologic findings in both eyes. Funduscopic examination showed an excavation in the inferotemporal part of the Optic Nerve Head (ONH) with serous macular detachment extending to the optic disc. Based on clinical examination and paraclinical imaging fluorescein Angiogeraphy (FAG) Optical Coherence Tomography (OCT), optic pit maculopathy was diagnosed and the patient underwent Juxtapapillary Laser Photocoagulation (JLP). After 2 years of follow-up, there were anatomical and functional improvements.

scholarly journals Case report of fibrous dysplasia in a pediatric patient: importance of adequate treatment to avoid malignization

2021 ◽  
Author(s):  
João Victor Bezerra Ramos ◽  
João Lucas Pordeus de Menezes ◽  
Louyse Jerônimo de Morais ◽  
Maurus Marques de Almeida Holanda
Keyword(s):  
Fibrous Dysplasia ◽  
Malignant Transformation ◽  
Adequate Treatment ◽  
Long Term Follow Up ◽  
History Of ◽  
Daily Headache ◽  
The Right ◽  
Temporal Bones

Background: Fibrous dysplasia is a congenital and benign bone tumor. There may be malignant transformation in some cases, with a mortality rate of 53.6%. Objectives and Methods: To describe a patient with fibrous dysplasia in childhood in the parietal and temporal bones, and to report the importance of surgical correction to prevent malignant transformation. The case was studied and came from a referral hospital – João Pesssoa, PB. Results: History of daily headache and bulging in the temporal and parietal regions on the right. Computed tomography revealed lesions in the aspect of “ground glass”. Surgery was performed with exposure of two lesions, with craniectomy, followed by cranioplasty. Such an approach should be recommended, since malignant transformation occurs in up to 1% of cases, but after radiotherapy this rate can reach 44% of cases, mainly osteosarcoma. In this case, the anatomopathological study revealed a diagnosis of fibrous dysplasia and the patient has been followed up for 20 years without recurrences, which are common in adolescence. Conclusions: It is important to make a differential diagnosis with malignant diseases, in addition to contraindicating radiotherapy to prevent malignant transformation; long-term follow-up is essential to avoid relapses and / or complications resulting from the disease.

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