scholarly journals Early Cognitive Impairment after Intracerebral Hemorrhage in the INTERACT1 Study

2017 ◽  
Vol 44 (5-6) ◽  
pp. 320-324 ◽  
Author(s):  
Shoujiang You ◽  
Xia Wang ◽  
Richard I. Lindley ◽  
Thompson Robinson ◽  
Craig S. Anderson ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Intracerebral Hemorrhage ◽  
Mini Mental State Examination ◽  
Multivariable Analysis ◽  
The Elderly ◽  
Background Data ◽  
Acute Intracerebral Hemorrhage ◽  
State Examination ◽  
Intensive Blood Pressure

Background: Data on cognitive impairment after acute intracerebral hemorrhage (ICH) are limited. This study is aimed at determining the frequency and predictors of cognitive impairment among participants of the pilot phase, Intensive Blood Pressure (BP) Reduction in Acute Cerebral Hemorrhage Trial (INTERACT1). Methods: INTERACT1 was an open randomized trial of early intensive (target systolic BP <140 mm Hg) compared with contemporaneous guideline-recommended BP lowering in 404 patients with elevated systolic BP (150–220 mm Hg) within 6 h of ICH onset. Cognitive impairment was defined by scores ≤24 on the Mini-Mental State Examination (MMSE) assessed by interview on follow-up at 90 days. Results: A total of 231 (64.5%) of 358 90-day survivors had MMSE scores for analyses, and 75 (32.5%) had cognitive impairment. In multivariable analysis, older age (OR 2.48, 95% CI 1.73–3.56 per 10-year increase; p < 0.001), female sex (OR 2.06, 95% CI 1.00–4.23; p = 0.049), prior ICH (OR 2.87, 95% CI 1.08–7.65; p = 0.035), high baseline National Institute of Health Stroke Scale score (OR 1.06, 95% CI 1.00–1.13; p = 0.044), and high mean systolic BP over the first 24 h post-randomization (OR 1.34, 95% CI 1.07–1.68/10 mm Hg increase; p = 0.011) were independently associated with cognitive impairment. Conclusions: One third of patients have significant cognitive impairment early after ICH, which is more frequent in the elderly, females, those with prior ICH, and more severe initial neurological deficit and with persistently high early systolic BP.

scholarly journals The Association between Longest-Held Lifetime Occupation and Late-Life Cognitive Impairment: Korean Longitudinal Study of Aging (2006–2016)

2020 ◽  
Vol 17 (17) ◽  
pp. 6270
Author(s):  
Hye-Jin Kim ◽  
Jin-Young Min ◽  
Kyoung-Bok Min
Keyword(s):  
Cognitive Impairment ◽  
Longitudinal Study ◽  
Mini Mental State Examination ◽  
Late Life ◽  
White Collar ◽  
The Elderly ◽  
Blue Collar ◽  
Modifiable Factors ◽  
State Examination

The association between longest-held lifetime occupation and late-life cognitive impairment: Korean Longitudinal Study of Aging (2006–2016). Backgrounds: Our study hypothesized that occupation in adulthood may be one of the modifiable factors in cognitive performance. This follow-up study aimed to examine whether there was an association between the longest-held occupation in a lifetime and cognitive impairment. Methods: This study used data from the 2006, 2012, and 2016 waves of the Korean Longitudinal Study of Aging, and a total of 1733 subjects aged over 65 were included. Longest-held occupation in a lifetime was classified into blue-collar, pink-collar, and white-collar. Cognitive function was evaluated using the Korean version of the Mini-Mental State Examination. Results: In males, no significant associations were observed. In females, on the contrary, risk of cognitive impairment in the blue-collar occupation was consistently higher than in the white-collar occupation over the 10-year follow-up (2006, OR = 2.49, 95% CI 1.05–5.88; 2016, OR = 2.17, 95% CI 1.02−4.65). Conclusions: Lifetime occupation should be taken into consideration in the process of screening for cognitive decline in the elderly, especially females. This study needs to be interpreted cautiously in view of inherent data and methodological limitations.

Prestroke Physical Activity and Poststroke Cognitive Performance

2020 ◽  
Vol 49 (6) ◽  
pp. 632-638
Author(s):  
Andreas Gammelgaard Damsbo ◽  
Janne Kaergaard Mortensen ◽  
Kristian Lundsgaard Kraglund ◽  
Søren Paaske Johnsen ◽  
Grethe Andersen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cognitive Impairment ◽  
Functional Outcome ◽  
Cognitive Performance ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Protective Measure ◽  
Multivariable Analyses ◽  
State Examination ◽  
Physical Activity Scale

<b><i>Introduction:</i></b> Physical activity (PA) is associated with a lower risk of stroke and stroke mortality as well as a favorable stroke outcome. PA may also prevent general cognitive decline. Poststroke cognitive impairment is both common and disabling, and focusing on all possible preventive measures is important. Studies on the effect of PA on poststroke cognitive performance are sparse, however. We therefore aimed to examine the association between prestroke PA and poststroke cognitive performance. <b><i>Methods:</i></b> We studied the correlation between prestroke PA and poststroke cognitive performance in a prespecified analysis in The Efficacy of Citalopram Treatment in Acute Ischemic Stroke (TALOS) trial. We used the Physical Activity Scale for the Elderly (PASE) to collect information on PA during the 7-day period before stroke. PA was quantified, and patients were stratified into quartiles based on their PASE score. Cognitive performance was measured using the Symbol Digit Modalities Test (SDMT) at 1 and 6 months and the Mini-Mental State Examination (MMSE) at 6 months. The functional outcome was assessed using the modified Rankin Scale (mRS). <b><i>Results:</i></b> In total, 625 of 642 patients (97%) completed the PASE questionnaire. The median age was 69 (interquartile range [IQR]: 60–77), and the median PASE score was 137 (82–205). Higher prestroke PASE quartiles (2nd, 3rd, and 4th, each compared to the 1st) were independently associated with a higher SDMT score at 1 month in the both the univariable and multivariable analyses (2nd: 3.99 points, 95% confidence interval [CI]: 1.01–6.97; 3rd: 3.6, CI: 0.6–6.61; 4th: 4.1, CI: 0.95–7.24). This association remained at 6 months. PA was not statistically associated with the MMSE score or mRS. <b><i>Conclusion:</i></b> Higher prestroke PA was associated with a better cognitive performance as measured by the SDMT at 1 and 6 months poststroke. We found no significant association between prestroke PA and functional outcome. Our results are encouraging and support further investigations of PA as a protective measure against poststroke cognitive impairment.

Cognitive Functioning in Patients with Cerebral Aneurysms Measured with the Mini Mental State Examination and the Telephone Interview for Cognitive Status

Neurosurgery ◽  
2006 ◽  
Vol 59 (4) ◽  
pp. 803-811 ◽  
Author(s):  
Joseph T. King ◽  
Michael L. DiLuna ◽  
Domenic V. Cicchetti ◽  
Joel Tsevat ◽  
Mark S. Roberts
Keyword(s):  
Cognitive Impairment ◽  
Subarachnoid Hemorrhage ◽  
Cognitive Functioning ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Telephone Interview ◽  
Cerebral Aneurysms ◽  
Cognitive Status ◽  
State Examination

Abstract BACKGROUND: Clinicians and researchers use brief instruments, such as the Mini Mental State Examination (MMSE) and the Telephone Interview for Cognitive Status (TICS), to measure cognitive functioning in patients with cerebral aneurysms. MMSE and TICS scores are often dichotomized to classify patients as cognitively impaired or not. Frequently, after an initial MMSE face-to-face evaluation, the TICS is used for follow-up assessments by telephone. METHODS: A cross-sectional cohort of patients with cerebral aneurysms completed the MMSE at baseline and the MMSE or TICS at the 12-month follow-up examination. Multivariate logistic regression adjusting for demographics was used to model cognitive impairment. MMSE and TICS results were compared using the MMSE as the “gold standard.” RESULTS: Eleven out of 171 (6%) patients had baseline MMSE scores less than 24, indicating cognitive impairment. Multivariate analysis showed that a history of subarachnoid hemorrhage was associated with cognitive impairment measured with the MMSE (odds ratio, 13.9; P = 0.021; C statistic = 0.87); there was no relationship between subarachnoid hemorrhage or treatment and TICS cognitive impairment (i.e., score &lt; 27). In patients without recent or interim invasive interventions that might affect cognition (n = 65), raw baseline MMSE and 12-month TICS scores had fair correlations (r = 0.30, P = 0.015); however, dichotomized scores had poor agreement, and TICS sensitivity and positive predictive value was 0% compared with the MMSE. CONCLUSION: The MMSE may be more sensitive than the TICS to the effects of subarachnoid hemorrhage on cognitive functioning. Raw MMSE and TICS scores are well correlated, but dichotomized MMSE and TICS scores are probably not interchangeable in this patient population.

scholarly journals Fatores intrínsecos do risco de queda de idosos no domicilio: estudo descritivo

2018 ◽  
Vol 16 (4) ◽  
pp. 480
Author(s):  
Izabel Cristina Luiz ◽  
Ana Karine Ramos Brum
Keyword(s):  
Home Environment ◽  
Elderly Population ◽  
Mini Mental State Examination ◽  
Monitoring Program ◽  
The Elderly ◽  
Average Score ◽  
Intrinsic Factors ◽  
Risk Of Fall ◽  
State Examination

Goal: to associate the intrinsic factors for risk of fall with the occurrence of falls in the home environment in elderly people with chronic diseases. Method: a descriptive study with a quantitative approach, conducted between June and July 2015 with 36 octogenarian elderly, participants of a multidisciplinary chronic disease monitoring program in the state of Rio de Janeiro. We applied the Downton Scale for data collection. Results: all the elderly underwent the Mini Mental State Examination and presented a 27 point average score; 86.1% presented high intrinsic risk for falls, although sensorial handicap (P = 0.09), previous falls (p = 0.35), drug use (p = 1) and ambulation (p = 1) did not present any significant association with the occurrence of the fall during the six months of follow-up. Conclusion: There was a high intrinsic risk of falling in the elderly population studied. Among the most prevalent factors were the previous falls and use of medications, especially hypotensive drugs.

scholarly journals To evaluate the utility of 10 warning signs questionnaire in assessment of cognitive function among elderly people

2016 ◽  
Vol 7 (01) ◽  
pp. 168-170
Author(s):  
Sunil Kumar Raina ◽  
Vishav Chander
Keyword(s):  
Cognitive Impairment ◽  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Warning Signs ◽  
Correlation Data ◽  
Urban Rural ◽  
State Examination

ABSTRACT Introduction: Routine screening of high-risk elderly people for early cognitive impairment using mini-mental state examination (MMSE) and its modifications may be constrained by demographic and other variables. Warning signs (as reported by family/caregivers) may be a useful alternative. The present data analysis was carried out with the aim to identify the role of 10 warning signs screen as an alternative tool for screening for cognitive impairment among elderly. Materials and Methods: For the purpose of this analysis (correlation), data available with us from a study conducted on the elderly population (60 years and above) from selected geographical areas (Migrant, Urban, Rural, and Tribal) of Himachal Pradesh was used. Results: A high statistically significant was found between scores on 10 warning signs screen and Hindi mental state examination/Bharmouri mental state examination (modifications of MMSE). Conclusions: Ten warning signs screen can be an important screening total for assessment of cognitive impairment in the elderly Indians.

The Longitudinal Stability of Cognitive Impairment in Schizophrenia

1995 ◽  
Vol 166 (5) ◽  
pp. 630-633 ◽  
Author(s):  
Philip D. Harvey ◽  
Leonard White ◽  
Michael Parrella ◽  
Katherine M. Putnam ◽  
Margaret M. Kincaid ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mini Mental State Examination ◽  
Reliability Study ◽  
Cognitive Changes ◽  
Retest Reliability ◽  
Schizophrenic Patients ◽  
One Year ◽  
Test Retest Reliability ◽  
State Examination

BackgroundSevere cognitive impairment affects many patients with schizophrenia, especially geriatric in-patients. Little is known about the course of this impairment, however.MethodTwo hundred and twenty-four geriatric schizophrenic in-patients were examined for changes in cognitive functioning over a one-year follow-up period, and 45 of them were assessed over a two-year period. In addition, the subset of 45 patients participated in a one-week and one-month test-retest reliability study of the instrument used to assess cognitive impairment, the Mini-Mental State Examination (MMSE).ResultsThe average MMSE scores did not change over a one- or two-year follow-up period. The test-retest reliability of the scale was extremely good at both retest intervals.ConclusionAmong the implications of these data are that cognitive changes in geriatric schizophrenic patients are very slow and are more consistent with a neurodevelopmental process than a neurodegenerative course.

scholarly journals Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil

2008 ◽  
Vol 30 (4) ◽  
pp. 346-349 ◽  
Author(s):  
Izabella Dutra de Abreu ◽  
Paula Villela Nunes ◽  
Breno Satler Diniz ◽  
Orestes Vicente Forlenza
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Diagnostic Accuracy ◽  
Cognitive Decline ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Elderly Subjects ◽  
Cognitive State ◽  
State Examination

OBJECTIVE: To determine the diagnostic accuracy of the Mini-Mental State Examination combined to the Informant Questionnaire on Cognitive Decline in the Elderly for the identification of mild cognitive impairment. METHOD: 191 elderly subjects were assessed with the Mini-Mental State Examination, and their informants were assessed with the Informant Questionnaire on Cognitive Decline in the Elderly. Subjects were divided into three groups according to their cognitive state (controls: n = 67, mild cognitive impairment: n = 65 and dementia: n = 59), which was ascertained by clinical and neuropsychological evaluation. The diagnostic accuracy of each test in the discrimination of diagnostic groups (mild cognitive impairment vs. controls, mild cognitive impairment vs. dementia and dementia vs. controls) was examined with the aid of ROC curves. We additionally verified if the combination of both tests would increase diagnostic accuracy for mild cognitive impairment and control identification. RESULTS: The combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly scores did not increase the Mini-Mental State Examination diagnostic accuracy in the identification of patients with mild cognitive impairment. CONCLUSIONS: The present data do not warrant the combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly as a sufficient diagnostic tool in the diagnostic screening for mild cognitive impairment.

scholarly journals Creativity, paranormal beliefs and cognitive impairment in the elderly

2015 ◽  
Vol 5 (2) ◽  
pp. 253-265
Author(s):  
Inmaculada Méndez ◽  
Julia García-Sevilla ◽  
Juan P. Martínez ◽  
Isabel García-Munuera ◽  
Ana Mª Bermúdez ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Religious Beliefs ◽  
Mini Mental State Examination ◽  
Belief System ◽  
The Elderly ◽  
Cognitive Status ◽  
Sociodemographic Characteristics ◽  
Paranormal Beliefs ◽  
The Relationship ◽  
State Examination

In the case of older people, aesthetic thought and creativity are ways to keep mind and imagination active by contributing to prevent cognitive decline. Furthermore, having a religious belief system or even a belief system or paranormal experiences has proved to be beneficial for the health of the elderly. The objective was to study the relationship between creativity, degree of cognitive impairment and paranormal beliefs. The existence of differences depending on sociodemographic characteristics was analyzed. A group of 36 elderly people (16 men) aged between 66 and 95 years were administered the Mini-Mental State Examination (MEC), the CREA Test and the Paranormal Beliefs Scale. The main outcomes include that: those with better cognitive status are more creative; the less creative subjects had more traditional religious beliefs and even greater superstition; the elderly with better cognitive status were the least superstitious. It is remarkable that men were more creative, while women excelled in traditional religious beliefs. The study allows reflecting on the importance of professionals who work with the elderly to carry out programs to encourage creativity and even collect information about the belief system.

scholarly journals The Montreal Cognitive Assessment (MoCA-Ina) versus the Mini-Mental State Examination (MMSE-Ina) For Detecting Mild Cognitive Impairment among The Elderly

2021 ◽  
Vol 20 (1) ◽  
pp. 164-169
Author(s):  
Ida Untari ◽  
Achmad Arman Subijanto ◽  
Diah Kurnia Mirawati ◽  
Rossi Sanusi
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Medical Science ◽  
The Elderly ◽  
Rank Test ◽  
Cognitive Tests ◽  
Level Of Education ◽  
And Gender ◽  
State Examination

Background: There are many neuropsychological instruments are used for screening cognitivefunctions in adults, with or without health problems such asthe MMSE-Ina and MoCA-Ina. Objectives:This study was designed to test the correlations and differences between MMSE-Inaand MoCA-Ina for early detection of decreasing cognitive function in the elderly. Methods: Total278 subjects were randomly selected from the 17 sub dictricts of Surakarta Municipality, CentralJava, Indonesia. Data collection was carried out in December 2018 and January 2019, withallsubjects individually interviewed using two cognitive tests (which lasted 30 – 45 minutes) alongwith physical and neurological examinations. The MMSE-Ina and MoCA-Ina scores of eachparticipant were correlated using the non-parametric Spearman rank test. Both scores werecompared based on level of education and gender. Results: The MoCa-Ina detected using MCIwas 215 (77.3%) while MMSE-Ina was 189 (68%), with 176 (63.3%) in severe 10 (3.5%).This study also showed a strong correlation between the MMSE-Ina and MoCA-Ina scores (r= 0.633 p < 0.000). The cut pointin this study were 23/24 for the MMSE-Ina and 25/26 for theMoCA-Ina which was less than 23 and 25,indicated cognitive impairment. Conclusion: TheMoCA-Ina is usedto screen cognitive impairment in the elderly. Bangladesh Journal of Medical Science Vol.20(1) 2021 p.164-169

scholarly journals The Effect of Low Impact Aerobic Exercise on Elderly with Dementia Cognitive Function

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Raden Ayu Tanzila ◽  
Sheilla Yonaka Lindri ◽  
Nindia Rahma Putri
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Aerobic Exercise ◽  
Elderly People ◽  
Memory Impairment ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Quasi Experimental ◽  
State Examination

In the elderly population, at least 10% of those over 65 years old and 50% of those over 80 years old experience a decline in cognitive function that varies from a cognitive decline due to normal aging (age-associated memory impairment/AAMI) to a mild cognitive decline (mild cognitive impairment/MCI) and dementia. Dementia is an intellectual disorder that affects the cognitive function, memory, language function, and visuospatial function that causes irreversible changes. Many studies have stated that lifestyle management in the form of increased physical activity has a protective effect on impaired cognitive functions, inhibits cognitive function decline, and even improves cognitive function in healthy elderly people and elderly with mild cognitive impairment to dementia. Low impact aerobic exercise is a physical activity that is useful and suitable for the elderly. This study aimed to determine the effect of low impact aerobic exercise on the cognitive function of elderly people with dementia. This was a quasi-experimental study with one group pretest-posttest method that involved elderly people from Tresna Werdha Teratai Palembang, South Sumatera, Indonesia who were selected based on the inclusion and exclusion criteria (n=38) from December 2018 to February 2019. Treatment provided was a low impact aerobic exercise 3 times a week for 5 weeks. Dementia was then measured before and after treatment using the Mini-mental State Examination (MMSE). The mean values of gymnastics before the treatment and after the treatment were 18.36±4.559 and 19.69±5.724, respectively. A p value of 0.000 was obtained using the Wilcoxon test. In summary, low impact aerobic exercise influences the cognitive function of the elderly with dementia. PENGARUH SENAM AEROBIK LOW IMPACT TERHADAP FUNGSI KOGNITIF USILA DENGAN DEMENSIAPada usia lanjut (usila), sedikitnya 10% dari yang berusia lebih dari 65 tahun dan 50% dari yang berusia lebih dari 80 tahun mengalami penurunan fungsi kognitif yang bervariasi mulai dari penurunan kognitif karena penuaan normal (age-associate memory impairment/AAMI) serta penurunan kognitif ringan (mild cognitive impairment/MCI) hingga demensia. Demensia adalah gangguan intelektual yang meliputi fungsi kognitif, daya ingat, bahasa, fungsi visuospasial, dan bersifat ireversibel. Banyak studi menyatakan bahwa manajemen gaya hidup berupa peningkatan aktivitas fisik mempunyai efek protektif terhadap gangguan fungsi kognitif, menghambat penurunan fungsi kognitif, serta bahkan meningkatkan fungsi kognitif pada usila yang sehat dan usila dengan penurunan fungsi kognitif ringan sampai demensia. Senam aerobik low impact merupakan aktifitas fisik yang bermanfaat dan cocok diberikan kepada usila. Penelitian ini bertujuan mengetahui pengaruh senam aerobik low impact terhadap fungsi kognitif usila dengan demensia. Penelitian ini merupakan studi quasi-experimental dengan metode pretest-posttest one group yang melibatkan usila dari Tresna Werdha Teratai Palembang, Sumatera Selatan, Indonesia yang dipilih berdasar atas kriteria inklusi dan eksklusi (n=38) dari bulan Desember 2018 hingga Februari 2019. Perlakuan yang diberikan berupa senam aerobik low impact 3 kali per minggu selama 5 minggu. Demensia kemudian diukur sebelum dan sesudah perlakuan menggunakan Mini-mental State Examination (MMSE). Nilai rerata senam sebelum perlakuan dan setelah perlakuan adalah 18,36±4,559 dan 19,69±5,724 masing-masing. Nilai p=0,000 didapatkan dengan menggunakan Uji Wilcoxon. Simpulan, senam aerobik low impact memengaruhi fungsi kognitif usila dengan demensia.

Sign in / Sign up

Export Citation Format

Share Document