Bibliometric Analysis of Hidradenitis Suppurativa Publication Trends from Asia and Australasia

2021 ◽  
pp. 1-4
Author(s):  
Devea R. De ◽  
Alyssa M. Thompson ◽  
Justine Seivright ◽  
Swetha Atluri ◽  
Amanda Ederle ◽  
...  
Keyword(s):  
Bibliometric Analysis ◽  
Hidradenitis Suppurativa ◽  
Case Reports ◽  
Treatment Options ◽  
Publication Trends ◽  
Level Of Evidence ◽  
Asian Patients ◽  
Pubmed Database ◽  
High Level ◽  
Study Type

<b><i>Introduction:</i></b> Hidradenitis suppurativa (HS), once an orphan disease, has gained increased interest world-wide. The most highly cited works in HS are from North America and Europe despite known phenotypic and epidemiological differences globally. Herein, we perform a bibliometric analysis to characterize HS publication trends in Asia and Australasia (AA) over the last decade. <b><i>Methods:</i></b> PubMed database was searched to identify HS-related articles and were analyzed for senior authorship, country of origin, article topic, and study design. <b><i>Results:</i></b> The search criteria yielded 163 articles from AA. Rapid increase in publications started in 2015 with 75% (123/163) of total articles published in the last half of the decade. Case reports/series were consistently the most published study type yearly and overall (49%, 80/163). Efforts were made to increase high level of evidence publications with both randomized controlled trials from Japan and Turkey including all Asian patients. China, Japan, and India were the leading publishing countries with Australia, Israel, and Turkey increasingly contributing in the last half of the decade. <b><i>Conclusions:</i></b> Advancements in HS research are encouraging with increases in publication numbers and diversity; however, more geographical diversity is needed in order to garner a better understanding of the disease and treatment options.

scholarly journals Sound Waves for Unsound Entities: An Electronic Search Study to Evaluate the Diagnostic Efficacy of Ultrasonography in Cysts and Tumors of Maxillofacial Region

2013 ◽  
Vol 14 (4) ◽  
pp. 586-589 ◽  
Author(s):  
GA Raviraj ◽  
DD Darshan ◽  
Girish Katti ◽  
NS Manikantan ◽  
AD Manoj Kumar ◽  
...  
Keyword(s):  
Preliminary Report ◽  
Imaging Modality ◽  
Case Reports ◽  
Low Cost ◽  
Sound Waves ◽  
Maxillofacial Region ◽  
Level Of Evidence ◽  
Diagnostic Efficacy ◽  
Electronic Search ◽  
High Level

ABSTRACT Objective The purpose of this electronic search study was to evaluate the diagnostic efficacy of ultrasonography in cysts and tumors of maxillofacial region. Materials and methods An electronic search was performed for articles published from January 1989 to august 2009. Results Only 30 publications were searched and 22 publications showed high level of evidence (4 review articles, 12 clinical studies, 2 case reports, 1 quantitative analysis, 2 research articles and 1 preliminary report) with total of more than 2000 patients. Conclusion Ultrasonography is a noninvasive, low cost procedure, and recommended as a complimentary imaging modality. How to cite this article Darshan DD, Katti G, Raviraj GA, Manikantan NS, Kumar ADM, Balakrishnan D. Sound Waves for Unsound Entities: An Electronic Search Study to Evaluate the Diagnostic Efficacy of Ultrasonography in Cysts and Tumors of Maxillofacial Region. J Contemp Dent Pract 2013; 14(4):586-589.

scholarly journals Evidence-Based Management of Gout - A Systematic Search and Review

2020 ◽  
Author(s):  
Md Abu Bakar Siddiq
Keyword(s):  
Risk Factors ◽  
Treatment Options ◽  
Evidence Based ◽  
Level Of Evidence ◽  
Pharmacological Agents ◽  
New Synthesis ◽  
Pubmed Database ◽  
Anti Inflammatory ◽  
Clinical Conditions

Gout is the most common form of inflammatory arthritis. Hyperuricaemia is the pre-requisite for gout and is influenced by variable modifiable and non-modifiable risk factors. Clinical features unique for gout are due to deposition of monosodium urate (MSU) crystal in articular and extra articular tissues. Among various treating agents, anti-inflammatory drugs and urate lowering therapies (ULT) are used widely and successfully, however, non-medicinal means are also effective in the disorder. In their updated guidelines, ACR (2012) and EULAR (2016) recommended both medicinal and non-medicinal approaches that could be used in treating gout, though some of the recommendations are based on lower level of evidence. Moreover, researchers&rsquo; continued effort in finding new gout managing agents appear promising, for example, role of Lesinurad in gout management (CLEAR1, CLEAR2). In this new synthesis the author is aimed to provide updated information on gout management based on a systematic review including published work within last ten years between 2008 and 2018 and for this purpose, using &lsquo;clinical trials in gout management&rsquo; string, published worked searched in PubMed database from 1st September 2018 to 30 October 2018. Besides the recent ACR and EULAR evidence based management guidelines, the author reviewed another 91 (total 93) articles to make this new draft &ndash; 39 articles describe role of pharmacological agents and 54 describe different gout risks, pharmacokinetics/pharmacodynamics of ULT, association between raised sUA level and renal impairment, efficacy of non-pharmacological agents in reducing sUA. According to published work, anti-inflammatory agent is the most appropriate drug group in mitigating inflammatory symptoms of gout, though they often adversely affect over other vital 2 organs with impaired function. Besides ULT, uricase analogues are also found useful in non refractory gout. Since anti-inflammatory agents and ULT contraindicate in some clinical conditions, intra-articular steroid and or adrenocorticotropic hormone (ACTH) are appropriate alternatives instead. However, head-to-head comparison between different NSAIDs, NSAID and prednisolone, NSAID and colchicine are yet to perform. Use of combined anti-inflammatory preparations in gout is also based on lower level of evidence. Regarding effective maximum dose and long-standing impact of ULT on vital organs we are yet to reach a conclusion. Likewise, non-medicinal approaches are widely using in achieving target sUA level, though some of them are based on biased study outcomes and or study with inadequate power, requiring further analysis. Among non-pharmacological approaches, life-style modification, restriction of purine rich diets, avoidance of gout inciting agents are important, but inconclusive. Educating patients&rsquo; about diseases, risk factors, available treatment options and side effects from them are also important in terms of achieving sUA level, nevertheless too much counseling sometimes could be worthless.

scholarly journals Publication characteristics of studies published in the The Spine Journal from 2005 to 2015

2019 ◽  
Author(s):  
Joseph Park ◽  
Joseph A. Gil ◽  
Justin Kleiner ◽  
Adam E.M. Eltorai ◽  
Alan H. Daniels
Keyword(s):  
Clinical Decision Making ◽  
Fold Increase ◽  
Clinical Decision ◽  
Funding Source ◽  
Chi Square ◽  
Level Of Evidence ◽  
Level I ◽  
High Level ◽  
Study Type ◽  
Number Of Citations

BACKGROUND CONTEXT: There is a growing demand for evidence-based- practices and informed clinical decision making supported by reliable, high-quality research.PURPOSE: To analyze trends in the level of evidence of publications and to evaluate the publication characteristics that influence the quality of research in The Spine Journal (TSJ)STUDY DESIGN: Comprehensive publication assessment.SAMPLE: All studies published in TSJ from the years 2005, 2007, 2009, 2011, 2013, and 2015 were reviewed and analyzed.OUTCOME MEASURES: Level of evidence, study type, funding source, author country, author department, and number of citations.METHODS:  Multivariable logistic regression, and multivariable linear regression analyses, and chi square tests were used to analyze the trends of published studies level of evidence, study type, the specialties of authors, author countries, number of citations, and funding sources.RESULTS: A total of 1,456 articles were evaluated. There was a decrease in the percentage of high level evidence (level 1 and 2) studies from 73.6% in 2005 to 49.8% in 2015 (p=0.0045). There was a significant increase in the percentage studies with reporting funding support (p<0.0001). Funded studies were more likely to have a higher level of evidence (p<0.0001). The percentage of studies from international authors increased from 17.8% in 2005 to 69.1% in 2015 (p<0.0001). The percentage of studies with orthopedic authors decreased from 67% in 2005 to 44.9% in 2015 with a corresponding increase in the percentage of studies with neurosurgeon authors from 14.4% in 2005 to 23.2% by 2015, as well as an increase in the percentage of studies with a collaboration of authors from both specialties from 5.1% in 2005 to 8.7% in 2015 (p = 0.0007). Orthopedic and neurosurgery collaboration in authorship did not affect the level of evidence of the studies nor the number of citations of the studies (p=0.7583). Earlier studies had a higher SCOPUS citation number but were not affected by the level of evidence (p=0.2515) nor the department of the author(s) (p=0.9107).CONCLUSIONS: The publication characteristics of articles in TSJ have evolved between 2005 and 2015 with a 3.9-fold increase in International authorship and a 32% decrease in the proportion of Level I and Level II studies. Inter-departmental collaboration, funding source, and country of origin may affect level of evidence and number of citations. Continued efforts to increase level of evidence should be considered.

scholarly journals Boerhaave syndrome: A rare cause of retrosternal pain

2020 ◽  
Vol 17 (2) ◽  
pp. 83-88
Author(s):  
Adna Kafedžić ◽  
Nedim Katica
Keyword(s):  
Chest Pain ◽  
Case Reports ◽  
Treatment Options ◽  
Acute Chest Pain ◽  
Rare Condition ◽  
Individual Case ◽  
Retrosternal Pain ◽  
Specialist Treatment ◽  
Boerhaave Syndrome ◽  
High Level

Acute chest pain is one of the biggest challenges in diagnostic and therapeutic terms due to a number of differential diagnostic options. Boerhaave syndrome is a rare condition, but at the same time one of the most lethal diseases of the gastrointestinal tract. For this reason, a high level of suspicion is required in patients with presenting retrosternal pain. Classic symptoms such as vomiting, chest pain, and subcutaneous emphysema may not always be present. The approach to the patient with Boerhaave syndrome is multidisciplinary. The patient needs urgent rehydration, antibiotic treatment and consultation with a surgery specialist. Treatment is based on the clinical picture of the patient, the location and size of the perforation, but the most important prognostic factor is the time of diagnosis. There are still no official guidelines for the treatment of this condition, and knowledge of treatment options is based on individual case reports from the literature.

scholarly journals Internal hernia of caecum through the foramen of Winslow

2019 ◽  
Vol 12 (7) ◽  
pp. e228239
Author(s):  
Faez Ayoob ◽  
Rami Michael ◽  
Zachary Chadnick ◽  
Charles Fasanya
Keyword(s):  
Ct Scan ◽  
Internal Hernia ◽  
Case Reports ◽  
Treatment Options ◽  
Right Hemicolectomy ◽  
X Rays ◽  
Foramen Of Winslow ◽  
Internal Hernias ◽  
Pubmed Database ◽  
Abdominal Ct Scan

Internal hernias through the foramen of Winslow are very rare. An 80-year-old female patient presented with epigastric and right upper quadrant pain associated with abdominal distention, nausea and vomiting for 1 day. A CT scan showed an internal hernia with terminal ileum and caecum identified within the lesser sac. The diagnosis was confirmed by laparotomy. A right hemicolectomy was performed to prevent further recurrence. We reviewed case reports with the same presentation by searching the Pubmed database using the keywords: ‘foramen Winslow hernia, cecum’. We identified 23 publications. Our review extracted the following information: presentation, anatomical findings, pathological causes and surgical management. Misdiagnosis was common due to the limitations of plain abdominal X-rays. Abdominal CT scan is now the preferred radiological study and is more effective in establishing a diagnosis. Surgical treatment options varied. Right hemicolectomy has emerged as the preferred procedure to decrease the rate of recurrence.

scholarly journals TNF-α inhibitors in the treatment of hidradenitis suppurativa

2019 ◽  
Vol 10 ◽  
pp. 204062231985164 ◽  
Author(s):  
Kevin T. Savage ◽  
Kelsey S. Flood ◽  
Martina L. Porter ◽  
Alexa B. Kimball
Keyword(s):  
Clinical Trials ◽  
Hidradenitis Suppurativa ◽  
Complex Disease ◽  
Case Reports ◽  
Treatment Options ◽  
Certolizumab Pegol ◽  
Case Series ◽  
Phase Iii ◽  
Two Phase ◽  
Tnf Α

Hidradenitis suppurativa (HS) is a complex disease with a dramatic impact on the quality of life of patients that it afflicts. Despite this, there are few treatment options offering long-term relief. The exact pathophysiology of HS is unclear, although the current theory involves follicular obstruction, rupture, and subsequent inflammation leading to fistula and abscess development in intertriginous skin. Several inflammatory modulators have been implicated in the development of HS, including tumor necrosis factor (TNF)-α as well as interleukin (IL)-1β, IL-10, and IL-17. Initial evidence for the use of TNF-α inhibitors in HS stemmed from recognition that inflammatory bowel disease patients treated with these medications saw a concurrent improvement in their HS symptoms. Early case reports and case series illustrated TNF-α inhibitors’ value in the treatment of HS. Later, two phase III clinical trials, PIONEER I and PIONEER II, demonstrated that adalimumab is an efficacious treatment for HS. Infliximab represents another effective HS treatment option with its main advantage being dosing flexibility. In contrast, clinical trials have failed to show evidence for application of etanercept in HS. There is limited data on other TNF-α inhibitors such as certolizumab-pegol and golimumab. This review outlines the history, dosing, response, and adverse effects of TNF-α inhibitors in the treatment of HS.

scholarly journals Investigating Research Hotspots and Publication Trends of Spinal Stenosis: A Bibliometric Analysis during 2000-2018

2020 ◽  
Author(s):  
Keda Yang ◽  
Lei Pei ◽  
Kaicheng Wen ◽  
Siming Zhou ◽  
Lin Tao
Keyword(s):  
Bibliometric Analysis ◽  
Spinal Stenosis ◽  
Posterior Longitudinal Ligament ◽  
The United States ◽  
Publication Trends ◽  
Mesh Terms ◽  
Pubmed Database ◽  
High Incidence ◽  
Occurrence Matrix ◽  
Research Hotspots

Abstract Background: Spinal stenosis is a common elderly disease, present in a variety of forms. High incidence forces researchers to pay more attention and give countermeasures. Our study aimed to conclude the knowledge hierarchy and research anticipation of spinal stenosis according to bibliometric analysis.Methods: Admitted published papers were obtained from Web of Science Core collection and PubMed database. Bibliometric analysis was conducted by using online analysis software CiteSpace and Bibliographic Item Co-Occurrence Matrix Builder (BICOMB). Exported major MeSH terms were further biclustered with gCLUTO according to co-word analysis. Then the research hotspots and publication trends were identified based on the high-frequency MeSH terms.Results: 5606 scientific literatures were retrieved about spinal stenosis and the number maintained a roughly increasing trend from 108 in 2000 to 512 in 2018, only declining in 2011. The United States is the country keeping an academic leadership in this field. And the journal SPINE was the most authoritative with total 695 articles and average 12.73 citations. There were 17 major and 18 expanded MeSH terms extracted after bibliometric analysis. Co-word and biclustering analysis revealed seven research hotspots involved in etiology, pathogenesis, clinical manifestation, conservative treatment, operative indication, internal implantation and postoperative complications. Conclusions: In this study, we revealed the research hotspots in spinal stenosis focusing on the pathogenesis and surgical treatment. Narrowing caused by the pathological change of flavum ligamentum hypertrophy and posterior longitudinal ligament ossification attracts more attention in recent years. Besides, minimally invasive surgery and internal implantation fixation are more valid in clinical. Refining pathological classification, optimizing surgical method and instrument property will be an expectable direction of spinal stenosis.

scholarly journals Sleep related painful erection: an algorithm for evaluation and management

2019 ◽  
Vol 29 (1) ◽  
Author(s):  
Maher Abdessater ◽  
Anthony Kanbar ◽  
Ahmed S. Zugail ◽  
Abdalla Al hammadi ◽  
Bertrand Guillonneau ◽  
...  
Keyword(s):  
Side Effects ◽  
Randomized Clinical Trials ◽  
Current Knowledge ◽  
Case Reports ◽  
Treatment Success ◽  
Treatment Decision ◽  
Rare Condition ◽  
Level Of Evidence ◽  
Phosphodiesterase Type 5 Inhibitors ◽  
Pubmed Database

Abstract Background Sleep related painful erection (SRPE) is a rare parasomnia consisting of nocturnal penile tumescence accompanied by pain that awakens the individual. Normal non-painful erections are experienced when awake. No penile anatomic abnormalities are present. No conclusive randomized clinical trial is present in the literature about the management of this rare condition. The aim of this article is to review the current knowledge about the management of SRPE and to suggest an algorithm to help physicians evaluate and manage SRPE. Material and methods A literature review was conducted through PubMed database using the terms: sleep, pain, painful, penile, and erection. The reference lists of the articles were also reviewed. The search returned 23 references that were published between 1987 and 2019. Results were presented in a descriptive manner. Results Treatment decision for now is based on reports of the treatment success, the sustainability of remission, the tolerability by the patients and the potential side effects of each medication. From data available in literature, Baclofen is the mostly used medication with a tolerable profile of adverse effects. Phosphodiesterase type 5 inhibitors are considered potential treatments and are already widely used and tolerated for other indications, but so far only 2 successful trials have been reported for SRPE. Cinitapride is very promising, but only one case was studied and no side effects were reported. Clozapine can be very dangerous although highly effective. Conclusion Based on the limited number of treatment trials and reported cases, the low level of evidence and the lack of randomized clinical trials, no treatment consensus for SRPE can be reached. We suggested a useful tool for clinicians: an algorithm for the management of SRPE to facilitate their access to the literature without exhaustive return to case reports and series upon each case faced.

scholarly journals Systematic review of mydriatics used for screening of retinopathy in premature infants

2019 ◽  
Vol 3 (1) ◽  
pp. e000448 ◽  
Author(s):  
Lisa Jean Kremer ◽  
David M Reith ◽  
Natalie Medlicott ◽  
Roland Broadbent
Keyword(s):  
Premature Infants ◽  
Retinopathy Of Prematurity ◽  
Case Reports ◽  
Combination Regimen ◽  
Efficacy And Safety ◽  
Limited Evidence ◽  
Level Of Evidence ◽  
Effective Combination ◽  
Eye Examination ◽  
High Level

IntroductionRoutine retinopathy of prematurity eye examinations are an important part of neonatal care, and mydriatic medicines are essential in dilating the pupil for the eye examination. There are concerns about the level of evidence for efficacy and safety of these mydriatic medicines.ObjectiveThis review evaluates both efficacy and safety evidence of mydriatics used during the retinopathy of prematurity eye examination.MethodSystematic literature review.ResultsThere is limited evidence guiding clinical practice for safety and efficacy of mydriatics. The majority of publications are underpowered and with an unclear to high level of bias. There are a wide variety of mydriatic regimens evaluated for efficacy and safety, and multiple regimens are associated with case reports.ConclusionsCurrent international guideline seems unnecessarily high, especially when the reviewed literature suggest that lower doses are effective, albiet from underpowered studies. The lowest effective combination regimen appears to be phenylephrine 1% and cyclopentolate 0.2% (1 drop). Microdrop administration of this regimen would further increase the safety profile, however, efficacy needs to be assessed.

scholarly journals A Radiographic Classification for Retrograde Peri-implantitis

2016 ◽  
Vol 17 (4) ◽  
pp. 313-321 ◽  
Author(s):  
Rucha Shah ◽  
Raison Thomas ◽  
AB Tarun Kumar ◽  
Dhoom Singh Mehta
Keyword(s):  
Bone Loss ◽  
Classification System ◽  
Case Reports ◽  
Treatment Options ◽  
Treatment Algorithm ◽  
Case Series ◽  
Apical Part ◽  
Pubmed Database ◽  
Standard Classification ◽  
Radiographic Classification

ABSTRACT Background Retrograde peri-implantitis (RPI) is an inflammatory disease that affects the apical part of an osseointegrated implant, while the coronal portion of the implant sustains a normal bone-to-implant interface. It is a diagnostic and therapeutic dilemma for implantologists. There is lack of a standard classification system and a definite treatment algorithm for the same. This article aims to introduce a classification system for RPI based on the radiographic amount of bone loss around an implant apex. Materials and methods A search of PubMed database was conducted with the keywords “retrograde peri-implantitis” and “implant periapical lesion.” Preoperative intraoral periapical (IOPA) radiographs of implants with RPI in case reports/case series were compiled. A total of 54 IOPAs from 36 articles were compiled and were assessed. Results Three different classes were proposed. The amount of bone loss from the apex of the implant to the most coronal part of radiolucency was calculated as a percentage of the total implant length and classified into one of the three classes: Mild, moderate, and advanced. Treatment options and prognosis have been suggested for each class. Conclusion The proposed classification may allow for an easy and reproducible radiographic assessment of the RPI lesion and may serve as a guideline to prognosis and treatment planning. How to cite this article Shah R, Thomas R, Kumar ABT, Mehta DS. A Radiographic Classification for Retrograde Periimplantitis. J Contemp Dent Pract 2016;17(4):313-321.

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