scholarly journals Human papillomavirus, gene mutation and estrogen and progesterone receptors in breast cancer: a cross-sectional study

2021 ◽  
Vol 38 ◽  
Author(s):  
Abdallah Mohammed Elagali ◽  
Ahmed Abdelbadie Suliman ◽  
Mohammed Altayeb ◽  
Anas Ibrahim Dannoun ◽  
Narasimha Reddy Parine ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Human Papillomavirus ◽  
Gene Mutation ◽  
Progesterone Receptors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Estrogen And Progesterone Receptors ◽  
Cross Sectional

Knowledge and awareness of human papillomavirus (HPV) among young adults – a cross-sectional study

2020 ◽  
Vol 2 (68) ◽  
pp. 94
Author(s):  
Larisa Tomescu ◽  
Denis Şerban ◽  
Nicoleta Nicolae ◽  
Florina Borozan ◽  
Ioan Sas
Keyword(s):  
Young Adults ◽  
Human Papillomavirus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals First Prospective Cross-Sectional Study on the Impact of Immigration Background and Education in Early Detection of Breast Cancer

Breast Care ◽  
2020 ◽  
pp. 1-7
Author(s):  
Elna Kuehnle ◽  
Wulf Siggelkow ◽  
Kristina Luebbe ◽  
Iris Schrader ◽  
Karl-Heinz Noeding ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
First Generation ◽  
Participation Rate ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
First Generation Immigrants ◽  
Cancer Early Detection

<b><i>Background:</i></b> Although immigrant health is an important issue in national health policy, there is a serious shortage of data in many countries. Most studies lack information on educational status, which is a major limitation. This prospective cross-sectional study analyzed a real-world breast cancer population on the influence of immigration background and educational status on participation in breast cancer early detection programs in the federal state of Lower Saxony, Germany. <b><i>Methods:</i></b> Data collection was conducted from 2012 to 2016 in six certified breast cancer centers using a standardized questionnaire for patients’ interview and tumor-specific data from the patients’ medical records. <b><i>Results:</i></b> 2,145/3,047 primary breast cancer cases were analyzed. 17.5% of our patients had a history of immigration, including <i>n</i> = 202 first-generation immigrants and <i>n</i> = 168 second-generation immigrants. Most of them were citizens of EU27 member states. No significant difference was seen in age, tumor stage, histology, grading, Ki-67, Her2/neu-status, and hormone receptor status compared to the native cohort. 100% participation rate in the breast cancer early detection programs were seen in patients with no school graduation. With regards to the national mammography screening program, participation decreased significantly with educational status (<i>p</i> = 0.0003). <b><i>Conclusions:</i></b> No tumor biological differences were seen between immigrants and German natives. In first-generation immigrants, early detection programs were well accepted despite sociocultural and language differences. Participation rate decreased significantly with higher education levels irrespective of country of origin. Immigration background does not have a negative effect on the participation in breast cancer screening. This mainly relates to immigrants from EU27 member states.

scholarly journals Nurses’ and midwives’ knowledge, attitudes, and acceptance regarding human papillomavirus vaccination in Ghana: a cross-sectional study

BMC Nursing ◽  
2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Nancy Innocentia Ebu ◽  
Gifty Esinam Abotsi-Foli ◽  
Doreen Faakonam Gakpo
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cancer Risk Factors ◽  
Cervical Cancer Risk ◽  
Nurses And Midwives

Abstract Background Nurses and midwives play important roles in educating the public on cervical cancer prevention strategies. Aim This study sought to assess nurses’ and midwives’ knowledge of, attitudes towards, and acceptance of human papillomavirus (HPV) vaccination in relation to their background characteristics. Methods A descriptive cross-sectional study using questionnaires was conducted with a convenience sample of 318 female nurses and midwives, ages 20 to 59, at the Korle-Bu Teaching Hospital in Ghana. The data were summarised using frequencies, percentages, chi-square tests, and Fisher’s exact tests. Results The results indicated that 41.5% (n = 132) of the participants had high levels of knowledge about cervical cancer risk factors, and 17.6% (n = 56) of the respondents had received at least one dose of the HPV vaccine. Reasons for receiving the HPV vaccination included advice from a colleague (12.9%, n = 41) and perceived threat of cervical cancer (11.7%, n = 37). Of the 262 respondents who had not been vaccinated, 24.45% (n = 78) strongly agreed and 28.0% (n = 89) agreed with the statement that there was limited information on HPV vaccination. Also, there were statistically significant associations between age (X2 = 23.746, p = 0.001), marital status (X2 = 14.758, p = 0.005), completed level of education (X2 = 21.692, p = 0.001), and duration of working at the hospital (X2 = 8.424, p = 0.038) and acceptance of HPV vaccination. Conclusions This study demonstrated gaps in knowledge about cervical cancer risk factors and attitudes towards HPV vaccination, indicating the need for targeted measures to improve knowledge and attitudes. Also, measures to increase acceptance of HPV vaccination among nurses and midwives should consider their sociodemographic characteristics.

scholarly journals Knowledge of breast cancer among medical students in Syrian Private University, Syria: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hlma Ismail ◽  
Mosa Shibani ◽  
Hanaa Wael Zahrawi ◽  
Ali Fouad Slitin ◽  
Mhd Amin Alzabibi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Medical Students ◽  
Clinical Features ◽  
Smoking Status ◽  
Private University ◽  
Cross Sectional Study ◽  
General Information ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Breast cancer is the most common cancer among women and the second leading cause of cancer death globally. Since early diagnosis is crucial to reducing mortality, high levels of knowledge regarding general information, risk factors, and symptoms are required among healthcare professionals to deliver breast cancer care. This study aimed to determine Syrian medical students’ knowledge about breast cancer in the fields of general knowledge, common clinical features, and risk factors. Methods This cross-sectional study was conducted at the Syrian Private University in October 2019 (Breast Cancer Awareness Month), Damascus, during the Syrian war crisis. Data were collected through self-administered surveys and analyzed using the Statistical Package for Social Sciences version 25.0 (SPSS Inc., United States). The chi-square test was applied to assess the relationship between the level of knowledge and gender. One way analysis of variance was performed to assess the overall differences in mean knowledge score by study year, GPA, mother’s education, and source of information. Unpaired Student’s T-test was used to analyze the differences in mean knowledge scores (continuous variable) based on smoking status and alcohol consumption. Results Of 320 students, 301 completed the questionnaire (response rate = 94.0%), of which 179(59.5%) were males. The study revealed above-average knowledge scores (total mean = 68.4%) regarding breast cancer, general information (71.9%), common clinical features (71.6%), and risk factors (71.6%). Clinical students (4th, 5th, and 6th years) scored higher compared with pre-clinical students (1st, 2nd, and 3rd years). Conclusion This study showed above-average knowledge scores regarding breast cancer. More efforts to correct misinformation, through reassessing the university curriculum and promoting awareness about breast cancer are required.

Evaluation of ER, PR, HER2 / neu Receptor Status in Breast Cancer - A Cross Sectional Study from Manipur

2021 ◽  
Vol 8 (29) ◽  
pp. 2595-2600
Author(s):  
Themthingla Zimik ◽  
Angelica Laiphrakpam ◽  
Deepa Longjam ◽  
Sushila Devi L
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
Public Awareness ◽  
Progesterone Receptors ◽  
Cross Sectional Study ◽  
Correct Treatment ◽  
Cross Sectional ◽  
Duct Carcinoma ◽  
Treatment Protocols ◽  
Screening Programs

BACKGROUND Breast cancer is the most common cancer in women worldwide and has surpassed cervical cancer in India. As a result of regular mammography screening programs and public awareness, early-stage breast cancer with better prognosis has occurred. Immunohistochemistry (IHC) is now a common practice in tumour evaluation which are of importance in diagnosis as well as for deciding the treatment and of prediction of prognosis in breast cancer. The present study was undertaken in view of correlating the histopathology of the tumour and IHC profile with respect to oestrogen receptor (ER), progesterone receptor (PR) and HER2 / neu. METHODS The study is a cross-sectional prospective analysis of patients with primary carcinoma of breast who are undergoing surgery over a period of 2 years from September 2017 to August 2019. All specimens were processed and stained with haematoxylin and eosin and immunohistochemistry was done for oestrogen and progesterone receptors and HER 2neu. RESULTS A total of 20 cases of breast carcinoma specimens were studied, whose age ranged from 24 - 72 years of age. All the 20 cases occurred in females. Infiltrating duct carcinoma was the most histological subtype noted in this study comprising 85 % (17 / 20) of cases. In the study 50 % (10/20) of the cases showed ER / PR positivity with negative HER2 / neu while 15 % (3/15) of cases were negative for ER / PR and HER2 / neu and only one case showed positivity for all three markers. 10 cases (50 %) had lymph node metastases in this study. CONCLUSIONS Breast cancer is the most commonly diagnosed malignancy in Indian women and is also the leading cause of cancer death in women worldwide. Assessment of receptor (ER, PR and HER – 2 / neu) status along with histopathological grading and staging will guide the clinicians to impart a correct treatment protocols to the patients. It will also be of great help in assessing the prognosis. KEYWORDS Breast Cancer, Histopathology, Immunohistochemistry

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