Abstract P036: Socioeconomic Status and Risk of Diabetes over 35 Years

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Lena M Bjorck ◽  
Christina Stahl-Heden ◽  
Masuma Novak ◽  
Wai Giang Kok ◽  
Annika Rosengren
Keyword(s):  
Socioeconomic Status ◽  
Population Sample ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Low Ses ◽  
Occupational Class ◽  
Skilled Workers ◽  
Unskilled Workers

Background and aim: The link between low socioeconomic status (SES) and CHD is well established but whether low SES is also an independent predictor for development of diabetes type 2 is not clear. The aim of this study was to investigate whether SES, measured as occupational class, predicted subsequent development of diabetes type 2 over an extended follow-up. Methods: A total of 6941 men 47-55 years old, without prior diabetes, from a population sample of 9998 men, were investigated during 1970-73. Of the men, 23.7% were unskilled workers, 27.2% were skilled workers, 19.7% occupied either a supervisory manual position or were lower officials, 17.9% were officials at an intermediate position, and 11.6% were professionals, executives or senior officials. Follow-up was achieved through the national Swedish patient registry. Results: A total of 900 men (13%) were registered at any time with a diagnosis of diabetes over a 35-year follow-up. Compared with men in the highest occupational class, men with intermediate non-manual occupations had a multiple-adjusted hazard ratio (HR) of 1.10, 95% confidence interval (CI) 0.84-1.44, lower officials and foremen had an HR of 1.37 (1.06-1.78), semiskilled and skilled workers 1.39 (1.08-1.78), and unskilled workers 1.66 (1.30-2.13) after adjustment for smoking at baseline, BMI, blood pressure, serum cholesterol, treatment for hypertension and leisure time physical activity. Conclusions: Low SES is an independent risk factor for long-term risk of diabetes in men, with a 66% independent higher risk in unskilled workers, compared to professionals/senior officials.

Abstract P216: Blood Pressure Level as Predictor for Developing Diabetes Type 2

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Christina Stahl-Heden@ ◽  
Lena M Bjorck ◽  
Masuma Novak ◽  
Wai Giang Kok ◽  
Per-Olof Hansson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Level ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Pressure Level ◽  
Normal Range

Introduction and Aim: The link between diabetes type 2 and hypertension is a well established with both factors parts of the metabolic syndrome. Whether hypertension is an independent predictor for diabetes type 2 development has been examined in previous studies, however with divergent findings. The aim of this study was to investigate whether hypertension, including mildly elevated blood pressure within the normal range predicted subsequent development of diabetes type 2 over an extended follow-up. Methods and Results: Data were derived from participants of the intervention group of the Gothenburg primary prevention study where a random sample of 7333 men aged 47-55 years and free of diagnosed diabetes underwent a screening investigation in 1970 to 1973. During a 32-year follow-up, 956 men (13%) were diagnosed with diabetes according to the Swedish hospital discharge register. Development of diabetes type 2 was positively correlated to age, BMI, systolic blood pressure (SBP) and diastolic blood pressure (DBP), serum cholesterol, hypertension treatment, non-manual occupation, high tobacco use, sedentary lifestyle at the midlife screening. In a Cox regression model which adjusted for BMI and other risk factors we calculated the multiple adjusted hazard ratio for developing diabetes type 2 according to blood pressure level. Compared to a reference level of systolic blood pressure (SBP) below 130 mm Hg, men with SBP of 130-139 mmHg, 140-149 mmHg and > 150 mmHg had a multiple adjusted hazard ratios (HRs) of 1.41 (95% confidence interval) 1.11–1.80), 1.38 (1.08–1.75) and 1.67 (1.35–2.07), respectively. Mid-life diastolic blood pressure over 90 mmHg was associated to an increased risk of developing diabetes type 2 (multiple adjust HRs of 1,60 1,21–2,11) Conclusion: In this population, at mid-life, hypertension as well as moderately elevated systolic blood pressure levels within the normal range was shown to be independent predictors of diabetes type 2.

scholarly journals Endo-Perio Lesion and Uncontrolled Diabetes

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Sara Dhoum ◽  
Kaoutar Laslami ◽  
Fatimazahraa Rouggani ◽  
Amal El Ouazzani ◽  
Mouna Jabri
Keyword(s):  
Female Patient ◽  
General Condition ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Purulent Discharge ◽  
Diagnosis And Prognosis ◽  
Uncontrolled Diabetes

This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. A 50-year-old female patient with uncontrolled diabetes type 2 is suffering from a purulent discharge coming from the upper right canine. Endodontic and periodontal treatments were realized with 36 months radiological and clinical follow-up with the collaboration of her internist doctor.

Eksplorasi Kesadaran Diri, Persepsi Dan Sikap Pada Individu Yang Memiliki Riwayat Keluarga Diabetes Melitus Tipe 2

2019 ◽  
Vol 1 (1) ◽  
pp. 52-62
Author(s):  
Mulia Mayangsari
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Family History ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Self Awareness ◽  
Perceptions And Attitudes ◽  
History Of ◽  
Diabetes Melitus

 Individuals who have a family history oftype 2 diabetes mellitus (DM) have a highrisk for type 2 diabetes. Type 2 diabetescan be prevented by improving modifiablerisk factors, supported by self-awareness,perceptions and attitudes of individualswho have a high family history of DM. Thisstudy used a qualitative phenomenologicaldesign. A Purposive Sampling techiniquewas applied to determine individuals whohad parents with type 2 diabetes. Nineindividuals participated in this study. AQualitative content analysis with Collaiziapproach used as a data analysis method.The main themes depicted individuals selfawareness,perceptions, & attitudes were:denials that diabetes caused by heredityfactors; misperception about diabetes;“traditional modalities” as a preventionmeasurement toward type 2 diabetes; andDM is perceived as a “threatening disease”.Further study is needed to examine indepth the themes that have been identifiedon the number of participants are morenumerous and varied.

Risk Factors Associated With Hyperuricemia in Patients with Diabetes Type 2: About 190 Cases

2020 ◽  
Vol 2 (1) ◽  
pp. 12-16
Author(s):  
Fennoun H ◽  
Haraj NE ◽  
El Aziz S ◽  
Bensbaa S ◽  
Chadli A
Keyword(s):  
Type 2 Diabetes ◽  
Heart Disease ◽  
Glycemic Control ◽  
Ischemic Heart Disease ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Ischemic Heart ◽  
Factors Associated ◽  
Patients With Diabetes

Introduction: Hyperuricemia is common Type 2 diabetes at very high cardiovascular risk. Objective: Evaluate the relationship between hyperuricemia and diabetes type 2, and determine its predictive factors in this population. Patients and Methods: Retrospective study cross including 190 patients with diabetes type 2 hospitalized Service of Endocrinology of CHU Ibn Rushd Casablanca from January 2015 to December 2017. Hyperuricemia was defined as a serum uric acid concentration> 70 mg/L (men) and> 60 mg/L (women). The variables studied were the anthropometric measurements), cardiovascular factors (tobacco, hypertension, dyslipidemia), and degenerative complications (retinopathy, neuropathy, kidney failure, ischemic heart disease). The analyzes were performed by SPSS software. Results: Hyperuricemia was found in 26.5% of patients with a female predominance (76%), an average age of 55.9 years, and an average age of 12.4ans diabetes. The glycemic control was found in 84.6% of cases with mean glycated hemoglobin 8.6%. Factors associated al hyperuricemia were the blood pressure in 86% (p <0.05), dyslipidemia in 76.3% of cases (p <0.001) with hypertriglyceridemia in 48.3% of cases (p <0.02), and a hypoHDLémie 28% (p <0.001). The age, obesity, smoking, and glycemic control were associated significantly n al hyperuricemia. The research of degenerative complications of hyperuricemia has objectified renal impairment (GFR between 15 and 60ml / min) chez47% (p <0.001), it was kind of moderate in 35.8% (p <0.01) and severe in 5.1% (p <0.02), ischemic heart disease was found in 34% of cases (p <0.01). Conclusion: In our study, hyperuricemia in type 2 diabetes is common in female patients, especially with hypertension, dyslipidemia, and renal failure. Other factors such as age, obesity, smoking is not associated with hyperuricemia in type 2 diabetics.

scholarly journals Investigating GSTT1 and GSTM1 null genotype as the risk factor of diabetes type 2 retinopathy

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Alamdar Dadbinpour ◽  
Mohammad Hasan Sheikhha ◽  
Mojtaba Darbouy ◽  
Mohammad Afkhami-Ardekani
Keyword(s):  
Risk Factor ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Gstm1 Null Genotype

Dementie bij diabetes type 2 onvermijdelijk

2011 ◽  
Vol 54 (12) ◽  
pp. 635-635
Author(s):  
Ymte Groeneveld
Keyword(s):  
Diabetes Type 2 ◽  
Diabetes Type

scholarly journals Neuroinflammation as a Common Denominator of Complex Diseases (Cancer, Diabetes Type 2, and Neuropsychiatric Disorders)

2021 ◽  
Vol 22 (11) ◽  
pp. 6138
Author(s):  
Serena Asslih ◽  
Odeya Damri ◽  
Galila Agam
Keyword(s):  
Cell Activation ◽  
Neuronal Degeneration ◽  
Complex Diseases ◽  
Diabetes Type 2 ◽  
Neuropsychiatric Disorders ◽  
Diabetes Type ◽  
Common Denominator ◽  
Cancer Type ◽  
Complex Disorders

The term neuroinflammation refers to inflammation of the nervous tissue, in general, and in the central nervous system (CNS), in particular. It is a driver of neurotoxicity, it is detrimental, and implies that glial cell activation happens prior to neuronal degeneration and, possibly, even causes it. The inflammation-like glial responses may be initiated in response to a variety of cues such as infection, traumatic brain injury, toxic metabolites, or autoimmunity. The inflammatory response of activated microglia engages the immune system and initiates tissue repair. Through translational research the role played by neuroinflammation has been acknowledged in different disease entities. Intriguingly, these entities include both those directly related to the CNS (commonly designated neuropsychiatric disorders) and those not directly related to the CNS (e.g., cancer and diabetes type 2). Interestingly, all the above-mentioned entities belong to the same group of “complex disorders”. This review aims to summarize cumulated data supporting the hypothesis that neuroinflammation is a common denominator of a wide variety of complex diseases. We will concentrate on cancer, type 2 diabetes (T2DM), and neuropsychiatric disorders (focusing on mood disorders).

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