Abstract MP34: Associations Muscle Quality, Muscle Strength, and Muscle Mass With All-Cause Mortality in Elderly Men and Women

Circulation ◽  
2019 ◽  
Vol 139 (Suppl_1) ◽  
Author(s):  
Chong-Do Lee ◽  
Samuel Lee
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Muscle Quality ◽  
Elderly Men ◽  
Men And Women ◽  
All Cause Mortality

scholarly journals Evaluation of muscle quality and quantity for the assessment of sarcopenia using mid-thigh computed tomography: a cohort study

2021 ◽  
Author(s):  
Hiroki Oba ◽  
Yasumoto Matsui ◽  
Hidenori Arai ◽  
Tsuyoshi Watanabe ◽  
Hiroki Iida ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Motor Function ◽  
Mass Measurement ◽  
Muscle Quality ◽  
Cross Sectional ◽  
Men And Women ◽  
Ct Attenuation Value

Abstract BackgroundPreviously, sarcopenia was diagnosed based on walking speed, grip strength and muscle mass. However, recent consensus has proposed a concern regarding the use of muscle mass measurement for sarcopenia diagnosis due to lack of accuracy; therefore, new assessment methods in clinical practice are required. We investigated the correlation between computed tomography (CT) and various motor function tests to assess the utility of CT as a potential diagnostic method for sarcopenia.MethodsIn total, 214 patients who were examined at our center during the study period (2016–2017) were included in the study. Single-slice CT scan of the mid-thigh region was performed, from which cross-sectional area (CSA) and CT attenuation value (CTV) of quadriceps femoris were evaluated for each subject. Other assessments included skeletal muscle mass index, muscle strength and physical performance. Furthermore, subjects were classified into four groups as per the Asia Working Group of Sarcopenia (AWGS) 2019 criteria as those with: normal, poor muscle function/strength (poor function), sarcopenia and severe sarcopenia.ResultsCSA and muscle strength exhibited the strongest correlation. Some physical performance tests showed the strongest correlation with CTV. The CSA was significantly lower in women with sarcopenia group and in both men and women with severe sarcopenia (all p < 0.01); furthermore, the CTV was significantly lower in women with poor-function and in both men and women with severe sarcopenia group (all p < 0.01).ConclusionsCSA mostly correlated with muscle strength, whereas CTV mostly correlated with physical performance. CT with measurements of CSA and CTV enables the evaluation of muscle mass and quality simultaneously. CT is believed to be useful in inferring evaluation of motor function and assessment of sarcopenia.

scholarly journals Evaluation of muscle quality and quantity for the assessment of sarcopenia using mid-thigh computed tomography: a cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroki Oba ◽  
Yasumoto Matsui ◽  
Hidenori Arai ◽  
Tsuyoshi Watanabe ◽  
Hiroki Iida ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Motor Function ◽  
Working Group ◽  
Assessment Tool ◽  
Muscle Quality ◽  
Men And Women ◽  
European Working

Abstract Background For the diagnosis of Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP) revised the algorisms in 2019, where they added computed tomography (CT) as an assessment tool not only for quantity but also for quality in research purpose. However, the evidence for clinical appreciation of CT has been lacking. Therefore, we investigated the correlation between CT and various motor function tests to assess the utility of CT as a potential diagnostic tool for sarcopenia. Methods In total, 214 patients who were examined at our center during the study period (2016–2017) were included in the study. Single-slice CT scan of the mid-thigh region was performed, from which cross-sectional area (CSA) and CT attenuation value (CTV) of quadriceps femoris were evaluated for each subject. Other assessments included skeletal muscle mass index by DXA and BIA, muscle strength and physical performance. Furthermore, subjects were classified into four groups as per the Asia Working Group of Sarcopenia (AWGS) 2019 criteria as those with: normal, poor muscle function/strength (poor function), sarcopenia and severe sarcopenia. Results Knee muscle strength correlated with CSA (r = 0.60) and the correlation was significantly greater than that with DXA and BIA. For physical performance, standing-up test correlated with CSA (r = − 0.20) and CTV (r = − 0.40) and walking speed with CTV (r = 0.43), which was significantly greater than that with DXA and BIA. The CSA was significantly lower in women with sarcopenia group and in both men and women with severe sarcopenia (all p < 0.01). Furthermore, CTV was significantly lower in women with poor-function and in both men and women with severe sarcopenia group (all p < 0.01). Conclusions CSA mostly correlated with muscle strength, whereas CTV mostly correlated with physical performance. CT with measurements of CSA and CTV enables the evaluation of muscle mass and quality simultaneously. CT is believed to be useful in inferring evaluation of motor function and assessment of sarcopenia.

Muscle quality characteristics of muscles in the thigh, upper arm and lower back in elderly men and women

2018 ◽  
Vol 118 (7) ◽  
pp. 1385-1395 ◽  
Author(s):  
Akito Yoshiko ◽  
Takashi Kaji ◽  
Hiroki Sugiyama ◽  
Teruhiko Koike ◽  
Yoshiharu Oshida ◽  
...  
Keyword(s):  
Quality Characteristics ◽  
Muscle Quality ◽  
Elderly Men ◽  
Upper Arm ◽  
Men And Women ◽  
Lower Back

scholarly journals Intracellular Water Content in Lean Mass as an Indicator of Muscle Quality in an Older Obese Population

2020 ◽  
Vol 9 (5) ◽  
pp. 1580
Author(s):  
Mateu Serra-Prat ◽  
Isabel Lorenzo ◽  
Mònica Papiol ◽  
Elisabet Palomera ◽  
Maria Bartolomé ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Water Content ◽  
Muscle Mass ◽  
Lean Mass ◽  
Gait Speed ◽  
Bioelectrical Impedance ◽  
Intracellular Water ◽  
Muscle Quality ◽  
Timed Up And Go ◽  
Cross Sectional

Background: In aged populations, muscle strength depends more on muscle quality than on muscle quantity, while all three are criteria for the diagnosis of sarcopenia. Intracellular water content (ICW) in lean mass (LM) has been proposed as an indicator of muscle quality related to muscle strength in older people. Objectives: To evaluate the relationship between the ICW/LM ratio, muscle strength and indicators of functional performance in obese older adults, and to assess the value of the ICW/LM ratio as an indicator of muscle quality. Methodology: Design: cross-sectional study. Population: persons aged 65–75 years with a body mass index of 30–39 kg/m2. ICW and LM were estimated by bioelectrical impedance. Hand grip, gait speed, unipedal stance test, timed up-and-go (TUG) test, Barthel score and frailty (Fried criteria) were assessed. Sarcopenia was established according to EWGSOP2 criteria. Results: Recruited were 305 subjects (66% women), mean age 68 years. The ICW/LM ratio correlated with the TUG test, gait speed and grip strength, and was also associated with sex, the unipedal stance test and frailty. Independently of age, sex and muscle mass, the ICW/LM ratio was related with gait speed, the TUG test and unipedal stance capacity. One person (0.3%) had sarcopenia defined as low muscle strength and low muscle mass, while 25 people (8.2%) had sarcopenia defined as low muscle strength and poor muscle quality (ICW/LM). With this last definition, sarcopenia was related to frailty, gait speed and the TUG test. Conclusions: ICW content in LM could be a useful muscle quality indicator for defining sarcopenia. However, more studies are required to confirm our findings for other populations.

Muscle morphology, enzyme activity and muscle strength in elderly men and women

1981 ◽  
Vol 1 (1) ◽  
pp. 73-86 ◽  
Author(s):  
A. Aniansson ◽  
G. Grimby ◽  
M. Hedberg ◽  
M. Krotkiewski
Keyword(s):  
Enzyme Activity ◽  
Muscle Strength ◽  
Elderly Men ◽  
Muscle Morphology ◽  
Men And Women

scholarly journals Comparison of methods to identify individuals with obesity at increased risk of functional impairment among a population of home-dwelling older adults

2021 ◽  
pp. 1-8
Author(s):  
Anne Lene Nordengen ◽  
Linn Kristin Lie Øyri ◽  
Stine Marie Ulven ◽  
Truls Raastad ◽  
Kirsten Bjørklund Holven ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Body Mass ◽  
Functional Impairment ◽  
Muscle Quality ◽  
Obese Women ◽  
Total Body Mass ◽  
Increased Risk ◽  
Total Body

Abstract Obesity is associated with increased muscle mass and muscle strength. Methods taking into account the total body mass to reveal obese older individuals at increased risk of functional impairment are needed. Therefore, we aimed to detect methods to identify obese older adults at increased risk of functional impairment. Home-dwelling older adults (n 417, ≥ 70 years of age) were included in this cross-sectional study. Sex-specific cut-off points for two obesity phenotypes (waist circumference (WC) and body fat mass (FM %)) were used to divide women and men into obese and non-obese groups, and within-sex comparisons were performed. Obese women and men, classified by both phenotypes, had similar absolute handgrip strength (HGS) but lower relative HGS (HGS/total body mass) (P < 0·001) than non-obese women and men, respectively. Women with increased WC and FM %, and men with increased WC had higher appendicular skeletal muscle mass (P < 0·001), lower muscle quality (HGS/upper appendicular muscle mass) (P < 0·001), and spent longer time on the stair climb test and the repeated sit-to-stand test (P < 0·05) than non-obese women and men, respectively. Absolute muscle strength was not able to discriminate between obese and non-obese older adults. However, relative muscle strength in particular, but also muscle quality and physical performance tests, where the total body mass was taken into account or served as an extra load, identified obese older adults at increased risk of functional impairment. Prospective studies are needed to determine clinically relevant cut-off points for relative HGS in particular.

scholarly journals Whole‐grain intake and risk of all‐cause mortality among elderly men and women: the Cache, County Study on Memory, Health and Aging

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Heidi Wengreen ◽  
Anna Quach ◽  
Adele Cutler ◽  
Ronald Munger ◽  
Christopher Corcoran
Keyword(s):  
Whole Grain ◽  
Elderly Men ◽  
Men And Women ◽  
All Cause Mortality ◽  
Cache County
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