Abstract P396: Association of Subjective Social Status With Allostatic Load in The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Amanda C McClain ◽  
Linda Gallo ◽  
Carmen R Isasi ◽  
Robert Kaplan ◽  
Michelle I Cardel ◽  
...  
Keyword(s):  
Heart Rate ◽  
Social Status ◽  
Allostatic Load ◽  
Subjective Social Status ◽  
Health Study ◽  
Metabolic System ◽  
Lower Odds ◽  
Logistic Regression Models ◽  
One Step ◽  
The U.S

Introduction: Subjective social status (SSS) is inversely related to allostatic load (AL) markers, but little is known in Hispanics/Latinos. We assessed the hypotheses that SSS would be inversely associated with total AL and subsystem scores, regardless of objective socioeconomic status (OSS). Methods: Data were from baseline of the HCHS/SOL (n = 12,722, aged 18-74y). We assessed SSS using a 10-step ladder. Participants identified on which step they stood in relation to other people in the U.S. Higher scores indicated higher SSS (range: 1-10). Participants self-reported OSS as household income, educational attainment, and employment status. AL was comprised of 16 physiological markers from the parasympathetic (n=2; heart rate variability), inflammation (n=2; C-reactive protein, white blood cell), metabolic (anthropometrics, lipids, glucose, insulin resistance; n=8), and cardiopulmonary (blood and pulse pressures, resting heart rate, lung function; n=4) subsystems. Each marker was assigned a score of 1 if the value exceeded clinical cut-offs (or high-risk quartiles) or the participant reported taking medication to alter the marker. Otherwise, the marker was assigned a score of 0. Scores were summed across the 16 markers to create an AL score (0-16), with higher scores indicating higher AL. Scores were then dichotomized as high (vs. low) if scores were ≥ AL and subsystem medians. Multivariate-adjusted, survey-weighted linear and logistic regression models tested the association of SSS with AL and subsystem scores. Results: Sample means (95% CI) for SSS and AL were 4.4 (4.3-4.5) and 4.2 (4.1-4.3), respectively. A one-step increase on the SSS ladder was associated with lower AL ((β(SE): -0.1(0.02), p=0.003) and metabolic system (-0.04(0.01), p=0.001) scores. After adjusting for OSS, the association between SSS and AL was attenuated (-0.03(0.02), p=0.09), but remained significant for metabolic system scores (-0.03(0.01), p=0.01). When modeling dichotomized AL, a one-step increase was associated with lower odds of high AL (Odds Ratio (OR); 95% Confidence Intervals (CI): 0.94 (0.91-0.98), p=0.001), high parasympathetic system (0.96 (0.93-1.00), p=0.03), and high metabolic system (0.95 (0.92-0.98)) scores. After adjusting for OSS, higher SSS remained associated with lower odds of high AL (0.95 (0.92-0.99), p=0.01) and high metabolic system (0.96 (0.92-0.99), p=0.01) scores, but the association between SSS and lower parasympathetic subsystem scores was attenuated (0.97 (0.94-1.00), p=0.08). SSS was not associated with inflammation or cardiopulmonary subsystems. Conclusions: Among Hispanics/Latinos living in the U.S, OSS attenuated the relationship between SSS and AL. SSS may be influencing AL through the metabolic system, and could provide unique psychological and biobehavioral targets for reducing metabolic risk disparities among Hispanics/Latinos living in the U.S.

scholarly journals Associations of Pregnancy History with BMI and Weight Gain in 45–54-Year-Old Women

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Diana C Pacyga ◽  
Melissa Henning ◽  
Catheryne Chiang ◽  
Rebecca L Smith ◽  
Jodi A Flaws ◽  
...  
Keyword(s):  
Menopausal Status ◽  
Health Study ◽  
Age At First Birth ◽  
First Birth ◽  
Critical Determinant ◽  
Lower Odds ◽  
Logistic Regression Models ◽  
Younger Women ◽  
Live Births ◽  
Pregnancy History

ABSTRACT Background Midlife women have a higher risk of cardiometabolic disease than younger women, but the lifelong biological/lifestyle factors responsible for this increase are unclear. Objectives We investigated whether pregnancy history is a risk factor for midlife overweight/obesity and evaluated potential hormonal mechanisms. Methods The Baltimore Midlife Women's Health Study, a prospective cohort, recruited 772 women aged 45–54 y. Women reported pregnancy characteristics via questionnaires, trained staff measured weight/height to calculate midlife BMI, and serum hormones were assessed by ELISA. Logistic regression models assessed associations of pregnancy history with risk of midlife overweight/obesity and BMI gain since age 18. We additionally explored whether associations differed by menopausal status, and whether midlife hormones mediated relationships of pregnancy history and midlife BMI. Results These premenopausal or perimenopausal women were 66% Caucasian/White and 30% African American/Black, with a median of 2 live births (range: 0–11) and median age at first birth of 27 y (range: 12–46 y). Women with 0 and ≥2 live births had lower odds of overweight/obesity than those with 1 birth (OR = 0.47; 95% CI: 0.23, 0.96; P = 0.04, and OR = 0.58; 95% CI: 0.35, 0.95; P = 0.03, respectively). Women with ≥2 live births also had lower odds of BMI gain than those with 1 birth (OR = 0.66; 95% CI: 0.41, 1.06; P = 0.08). Furthermore, women who were older at their first birth had lower odds of overweight/obesity (OR = 0.96; 95% CI: 0.92, 1.00; P = 0.03) and BMI gain (OR = 0.97; 95% CI: 0.93, 1.00; P = 0.06). Number of pregnancies and age at last pregnancy were not associated with midlife overweight/obesity or BMI gain. Associations did not differ by menopausal status and were not explained by midlife hormones. Conclusions Earlier childbirth and having 1 child increased women's risk of midlife overweight/obesity and BMI gain since age 18. Additional studies should focus on women's childbearing years as a critical determinant of midlife metabolic health.

scholarly journals Association between Dietary Pattern and Periodontitis—A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4167
Author(s):  
Ersin Altun ◽  
Carolin Walther ◽  
Katrin Borof ◽  
Elina Petersen ◽  
Berit Lieske ◽  
...  
Keyword(s):  
Cohort Study ◽  
Periodontal Diseases ◽  
Gingival Recession ◽  
Population Based ◽  
Cross Sectional Study ◽  
Health Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lower Odds ◽  
Logistic Regression Models

The aim of the study was to investigate the relationship between specific known dietary patterns and the prevalence of periodontal disease in a northern population-based cohort study. We evaluated data from 6209 participants of the Hamburg City Health Study (HCHS). The HCHS is a prospective cohort study and is registered at ClinicalTrial.gov (NCT03934957). Dietary intake was assessed with the food frequency questionnaire (FFQ2). Periodontal examination included probing depth, gingival recession, plaque index, and bleeding on probing. Descriptive analyses were stratified by periodontitis severity. Ordinal logistic regression models were used to determine the association. Ordinal regression analyses revealed a significant association between higher adherence to the DASH diet/Mediterranean diet and lower odds to be affected by periodontal diseases in an unadjusted model (OR: 0.92; 95% CI: 0.87, 0.97; p < 0.001/OR: 0.93; 95% CI: 0.91, 0.96; p < 0.001) and an adjusted model (age, sex, diabetes) (OR: 0.94; 95% CI: 0.89, 1.00; p < 0.0365/OR: 0.97; 95% CI: 0.94, 1.00; p < 0.0359). The current cross-sectional study identified a significant association between higher adherence to the DASH and Mediterranean diets and lower odds to be affected by periodontal diseases (irrespective of disease severity). Future randomized controlled trials are needed to evaluate to which extent macro- and micronutrition can affect periodontitis initiation/progression.

Influences of subjective social status, control and perfectionism on international students' cross-cultural transition

2015 ◽  
Author(s):  
◽  
Chu-Chun Fu
Keyword(s):  
International Students ◽  
Social Status ◽  
Self Efficacy ◽  
Satisfaction With Life ◽  
Outcome Expectations ◽  
Subjective Social Status ◽  
Mediation Effect ◽  
Outcome Expectation ◽  
Sense Of Control ◽  
The U.S

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This study examined the influences of subjective social status, sense of control, and perfectionistic discrepancy on career development outcomes and satisfaction with life among 233 Chinese and Taiwanese international students before and after they study abroad in the U.S. The results showed that subjective social status at Time-1 was significantly associated with career outcome expectations, career search self-efficacy, and satisfaction with life at Time-2, but not significantly associated with Time-2 career adaptability. Post-arrival sense of control fully mediated the link between subjective social status in home country with career outcome expectations, career search self-efficacy, and satisfaction with life in the U.S. Moreover, a moderated-mediation effect was found, in which perfectionistic discrepancy weakened the sense of control-career outcome expectation association in the mediation model of subjective social status and career outcome expectation by sense of control. Additional results are provided. Implications of these findings are outlined.

DOES LOWER SUBJECTIVE SOCIAL STATUS YIELD RISKIER BIOMARKER PROFILES?

2014 ◽  
Vol 47 (06) ◽  
pp. 746-761 ◽  
Author(s):  
OMER GERSTEN ◽  
PAOLA S. TIMIRAS ◽  
W. THOMAS BOYCE
Keyword(s):  
Social Status ◽  
Allostatic Load ◽  
Subjective Social Status ◽  
Negative Finding ◽  
Biomarkers Of Aging ◽  
The Social ◽  
Aging Study ◽  
Nationally Representative ◽  
Taiwanese Men ◽  
The One

SummaryBoth objective and, more recently, subjective measures of low social status have been linked to poor health outcomes. It is unclear, however, through which precise physiological mechanisms such standing may influence health, although it has been proposed that those of lower status may have biomarker profiles that are more dysregulated (and hence pose a greater risk for poorer health). The main objective of this study was to investigate whether lower subjective social standing is associated with riskier neuroendocrine biomarker profiles. Data were from the Social Environment and Biomarkers of Aging Study (SEBAS), a nationally representative survey of Taiwanese men and women (ages 54–91) conducted in Taiwan in 2000. Five neuroendocrine markers (cortisol, dehydroepiandrosterone sulphate (DHEAS), adrenaline, noradrenaline and dopamine) were analysed both separately and collectively in an index termed neuroendocrine allostatic load (NAL) in relation to status – both self-reported and as measured through objective socioeconomic status (SES) indicators. For the biomarker DHEAS, some connection was found between its levels and the measures of status, but for the other markers and the NAL index almost no connection was found. The overall negative finding of this paper would be further supported with more and different measures of neuroendocrine system function and a reordering of the subjective social status questions in the survey such that the one probing about status in the community (that has no prompt) was asked before the one probing about status in all of Taiwan (which has a SES prompt).

scholarly journals Subjective Social Status and Objective Health Among Older People in England. A Longitudinal Approach With Biomarkers

2022 ◽  
Author(s):  
Lindsay Richards ◽  
Asri Maharani ◽  
Patrick Präg
Keyword(s):  
Older People ◽  
Social Status ◽  
Allostatic Load ◽  
Parental Education ◽  
Methodological Approach ◽  
Objective Measure ◽  
Subjective Social Status ◽  
Objective Health ◽  
The Status ◽  
New Evidence

Subjective social status has a known association with health, whereby better health outcomes are observed for those with higher perceived status. However, in this article we offer new evidence on the status–health relationship using a rigorous methodological approach that considers both observed and unobserved confounders. We use 14 years of data from the English Longitudinal Study of Aging and derive a measure of allostatic load with biomarkers as an objective measure of health. We apply ‘within–between’ panel regression models which reveal the expected association between subjective status and health when comparing participants (the ‘between’ estimate), but no association when examining temporal variation within participants (the ‘within’ estimate). When controlling for personality traits, optimism, and parental education the ‘between’ association between subjective status and allostatic also load disappears. These results suggest that perceived status is not a pathway to health, in and of itself, among older people.

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