scholarly journals Phytochemical Constituents and Anti-inflammatory Activities of <i>Momordicaaugustisepala</i> Seed and Stem Species Grown in Nigeria

2020 ◽  
Vol 8 (4) ◽  
pp. 54
Author(s):  
Ezekiel Gbadebo Adeyeni ◽  
Ezekiel Temidayo Ayodele ◽  
Taofik Adewale Adedosu ◽  
Olusola Nathaniel Majolagbe ◽  
Ruth Adeola Adeyeni
Keyword(s):  
Stem Species ◽  
Phytochemical Constituents ◽  
Anti Inflammatory

scholarly journals Phytochemical Analysis, Pharmacological and Safety Evaluations of Halophytic Plant, Salsola cyclophylla

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2384
Author(s):  
Hamdoon A. Mohammed ◽  
Mohsen S. Al-Omar ◽  
Salman A. A. Mohammed ◽  
Ahmad H. Alhowail ◽  
Hussein M. Eldeeb ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
High Concentration ◽  
Halophytic Plant ◽  
Anti Oxidant ◽  
Aqueous Ethanolic Extract ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Dpph Scavenging ◽  
Anti Inflammation

Salsola cyclophylla, an edible halophyte, is traditionally used for inflammation and pain. To confirm the claimed anti-inflammatory and analgesic properties, a detailed study on respective pharmacological actions was undertaken. The activities are contemplated to arise from its phytoconstituents. The LC-MS analysis of S. cyclophylla 95% aqueous-ethanolic extract revealed the presence of 52 compounds belonging to phenols, flavonoids, coumarins, and aliphatics class. A high concentration of Mn, Fe, and Zn was detected by atomic absorption spectroscopic analysis. The ethyl acetate extract showed the highest flavonoid contents (5.94 ± 0.04 mg/g, Quercetin Equivalents) and Fe2+-chelation (52%) potential with DPPH radicals-quenching IC50 at 1.35 ± 0.16 mg/mL, while the aqueous ethanolic extract exhibited maximum phenolics contents (136.08 ± 0.12 mg/g, gallic acid equivalents) with DPPH scavenging potential at IC50 0.615 ± 0.06 mg/mL. Aqueous ethanolic extract and standard quercetin DPPH radicals scavenging’s were equal potent at 10 mg/mL concentrations. The aqueous ethanolic extract showed highest analgesic effect with pain reduction rates 89.86% (p = 0.03), 87.50% (p < 0.01), and 99.66% (p = 0.0004) after 60, 90, and 120 min, respectively. Additionally, aqueous ethanolic extract exhibited the highest anti-inflammation capacity at 41.07% (p < 0.0001), 34.51% (p < 0.0001), and 24.82% (p < 0.0001) after 2, 3, and 6 h of extract’s administration, respectively. The phytochemical constituents, significant anti-oxidant potential, remarkable analgesic, and anti-inflammatory bioactivities of extracts supported the traditionally claimed anti-inflammatory and analgesic plant activities.

scholarly journals Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review

2018 ◽  
Vol 64 (3) ◽  
pp. 50-61 ◽  
Author(s):  
Ighodaro Igbe ◽  
Osaze Edosuyi ◽  
Agbonlahor Okhuarobo
Keyword(s):  
Drug Development ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Stem Bark ◽  
Deciduous Tree ◽  
Drug Candidates ◽  
Medicinal Properties ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Novel Drug

Summary Cussonia barteri Seem (Araliaceae) is a deciduous tree growing in savannah of Africa. Ethnomedicinally, it is used in Africa as an analgesic, anti-malarial, anti-inflammatory, anti-anaemic, anti-diarhoea, anti-poison, ani-pyschotic and anti-epileptic agent. This review provides a brief summary on the phytochemical screenings, ethnomedicinal and pharmacological applications of various parts of C. barteri. Leaves, stem bark and seed of C. barteri have been shown to be rich in saponins, flavonoids, phenols, sugars and alkaloids. Some of these constituents have been isolated and elucidated from C. barteri. Several compounds isolated from plant include triterpenes, saponins, polyenyne and quinic esters. Phytochemical constituents are also partly responsible for biological activities of C. barteri. Extracts and components isolated from the plant have demonstrated neuropharmacological, anti-larvicidal, anti-microbial, anti-inflammatory and antioxidant activities. Overall, the insights provided by this review reinforce the potential of C. barteri for drug development and create the need for further scientific probe of constituents of the plant with the aim of developing novel drug candidates.

scholarly journals ETHNO-PHARMACOLOGICAL AND PHYTOCHEMICAL CONSTITUENTS REVIEW OFECHINOPS ECHINATUS ROXB.

2015 ◽  
Vol 7 ◽  
pp. 69
Author(s):  
Qudsia Bano ◽  
Keyword(s):  
Evaluation Methods ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Anti Inflammatory

EchinopsechinatusRoxb. is a traditional plant that use medically traditional prescribing system. E. echinatus found in different in regions of Pakistan and India. Different evaluation methods are wereuse to know the phytochemical and pharmacological activities such as anti-inflammatory, Diuretic, analgesic, anti fertility of the plant. The aim of this review to summarized the works on E.

scholarly journals A Review on Natural Plants for Phytochemical Constituents and Pharmacological Activities

2021 ◽  
Vol 11 (2) ◽  
pp. 232-236
Author(s):  
K Muni Raja Lakshmi ◽  
M. Kiran ◽  
K. Sai Prasanna
Keyword(s):  
Medicinal Plants ◽  
Antioxidant Properties ◽  
Volatile Oil ◽  
Calotropis Procera ◽  
Pharmacological Activities ◽  
Antioxidant Agents ◽  
Phytochemical Constituents ◽  
Natural Plants ◽  
Anti Inflammatory ◽  
Anti Fungal

The present review aims for the study of phytoconstituents and pharmacological activities of some natural plants. The traditional medicinal plants have been found to acquire therapeutic activities significantly antimicrobial, anti-inflammatory antibacterial, anti-fungal, antioxidant properties etc. The plant-derived constituents are majorly for the aliments of used skin disease diabetes, bronchitis, asthma, arthritis, dry cough, ulcer and fever. The antimicrobial activity of the following plants like Justicia adathoda, Lantana Camara, Acacia leucophloea, Holoptelea integrifolia, Calotropis Procera, chlorophytum tuberosum, Bombax ceiba, Bacopa monnieri, Wedelia trilobata, Jatropha gossypifolia were obtained from the extraction of either  leaves, stem or flowers by using ethanol, methanol, aqueous, petroleum ether, chloroform. The phytochemical constituents of the extract have been shown the presence of alkaloids, glycosides, cardiac glucosides tannins, proteins, carbohydrates, saponin, quinines, triterpenes, steroids, polyphenolic, volatile oil, phenols, starch sugar, amino acid, resin and organic acids. This study evidenced the possible use of the mentioned plants as a source of natural medicines which are used as an antimicrobial, anti-inflammatory, anti-bacterial, anti-fungal, antioxidant agents. Keywords:  Medicinal plants, Antimicrobial, Anti-inflammatory, Antioxidants.

scholarly journals EVALUATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT OF WILD MUSHROOMS COLLECTED FROM HIMACHAL PRADESH

2017 ◽  
Vol 10 (3) ◽  
pp. 467 ◽  
Author(s):  
Aarti Bains ◽  
Astha Tripathi
Keyword(s):  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Total Phenol ◽  
Wild Mushrooms ◽  
Mushroom Species ◽  
Scavenging Effect ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Free Radical Scavenging Assay ◽  
Pleurotus Floridanus

ABSTRACTObjective: The objective of this study is to elucidate phytochemical contents, antioxidant, and anti-inflammatory activity of wild mushrooms collectedfrom Himachal Pradesh.Methods: Quantitative analysis of phytochemical constituents was carried out using standard methods while 1,1 diphenylpicrylhydrazyl nitric oxide,hydrogen peroxide-free radical scavenging assay were used to evaluate the antioxidant properties of selected wild mushrooms. Anti-inflammatorycapacity of samples was evaluated by human red blood cell membrane stabilization and albumin denaturation inhibition method.Results: The results obtained revealed that Pleurotus floridanus showed higher total phenol, flavonoid carotenoid, and ascorbic acid contentsof 61.13±2.3 mg/g, 15.2±1.13 mg/g, 12.42±0.42 μg/g, 17.36±0.40 μg/g, and 14.55±0.58 mg/g. All the species showed antioxidant potential, butP. floridanus proved to be more active while Macrocybe sp. proved to be least one.Conclusion: The mushroom species analyzed have been showed to be good source of phytoconstituents, antioxidants, and also possess antiinflammatoryproperties, thus can be used in the management of oxidative stress-induced disease.Keywords: Wild mushrooms, Scavenging effect, Total phenol, Antioxidant, Anti-inflammatory.

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