Spiral CT Analysis of the Effect of Long-Term Heavy-Load Wrist Movement on Metacarpal Bone Structure

2020 ◽  
Vol 10 (4) ◽  
pp. 847-852
Author(s):  
Lirong Zhou
Keyword(s):  
Cortical Bone ◽  
Cancellous Bone ◽  
Three Dimensional ◽  
Spiral Ct ◽  
Metacarpal Bone ◽  
Bone Volume ◽  
Control Group ◽  
Heavy Load ◽  
Volume Percentage

In order to analyze the influence of long-term heavy-load wrist exercise on metacarpal structure based on spiral CT, the metacarpal data of five groups of long-term heavy-load wrist athletes and volunteers are compared. The measurement parameters are cancellous bone volume, cortical bone volume, cancellous bone volume percentage and cortical bone volume percentage. After three-dimensional reconstruction and three-dimensional image cutting of metacarpal CT images and comparing the measured parameters, the volume of cancellous metacarpal bone in the experimental group is larger than that in the control group, which indicates that long-term and heavy-load wrist exercise can produce stress stimulation on metacarpal bone, which can reconstruct bone tissue and change its composition.

scholarly journals Cortical Bone Modifications after Radiotherapy: Cortex Porosity and Osteonal Changes Evaluated Over Time

2021 ◽  
Vol 32 (1) ◽  
pp. 9-15
Author(s):  
Juliana Simeão Borges ◽  
Gustavo Davi Rabelo ◽  
Milena Suemi Irie ◽  
João Lucas Carvalho Paz ◽  
Rubens Spin-Neto ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Cortical Thickness ◽  
Bone Microarchitecture ◽  
Total Porosity ◽  
Control Area ◽  
Bone Volume ◽  
Control Group ◽  
Significant Difference ◽  
Area And Perimeter ◽  
Haversian Canals

Abstract Aiming to evaluate cortical bone microarchitecture and osteonal morphology after irradiation, twelve male New Zealand rabbits were used. The animals were divided: control group (no radiation-NIr); and 3 irradiated groups, sacrificed after: 7 (Ir7d); 14 (Ir14d) and 21 (Ir21d) days. A single radiation dose of 30 Gy was used. Computed microtomography analyzed the cortical microarchitecture: cortical thickness (CtTh), bone volume (BV), total porosity (Ct.Po), intracortical porosity (CtPo-cl), channel/pore number (Po.N), fractal dimension (FD) and degree of anisotropy (Ct.DA). After scan, osteonal morphology was histologically assessed by means: area and perimeter of the osteons (O.Ar; O.p) and of the Haversian canals (C.Ar; C.p). Microtomographic analysis were performed by ANOVA, followed by Tukey and Dunnet tests. Osteon morphology analyses were performed by Kruskal-Wallis, and test Dunn’s. Cortical thickness was significant difference (p<0.010) between the NIr and irradiated groups, with thicker cortex at Ir7d (1.15±0.09). The intracortical porosity revealed significant difference (p<0.001) between irradiated groups and NIr, with lower value for Ir7d (0.29±0.09). Bone volume was lower in Ir14d compared to control. Area and perimeter of the osteons were statistically different (p<0.0001) between NIr and Ir7d. Haversian canals also revealed lower values (p<0.0001) in Ir7d (80.57±9.3; 31.63±6.5) compared to NIr and irradiated groups. Cortical microarchitecture was affected by radiation, and the effects appear to be time-dependent, mostly regarding the osteons morphology at the initial days. Cortex structure in Ir21d revealed similarities to control suggesting that microarchitecture resembles normal condition after a period.

scholarly journals Effects of long-term occlusal hypofunction and its recovery on the morphogenesis of molar roots and the periodontium in rats

2012 ◽  
Vol 83 (4) ◽  
pp. 597-604 ◽  
Author(s):  
Masahide Motokawa ◽  
Akiko Terao ◽  
Ersan I. Karadeniz ◽  
Masato Kaku ◽  
Toshitsugu Kawata ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Male Rats ◽  
Control Group ◽  
Disuse Atrophy ◽  
Micro Computed Tomography ◽  
Root Area ◽  
Wistar Strain ◽  
Length Width ◽  
Recovery Groups

ABSTRACT Objectives: To investigate the effects of long-term, artificially created, hypofunctional occlusion and its recovery on the morphology of rat molar roots. Material and Methods: Eighteen 5-week-old Wistar-strain male rats were randomly divided according to their periodontal conditions into normal, hypofunctional, and recovery groups (n  =  6 in each). In the experimental hypofunctional and recovery groups, a bite-raising appliance was set to produce hypofunction at the molar region. All groups were analyzed at 16 weeks of age using three-dimensional micro-computed tomography. Root length, width, and area as well as the thickness and the area of the periodontal ligament (PDL) space of the maxillary first molar were calculated. Results: Roots were longer and narrower in the hypofunctional group than in the control group. The mesial root in particular showed a dramatic change. Root area also decreased significantly in the hypofunctional group compared to the other groups. Moreover, the PDL thickness and area decreased significantly in the hypofunctional group compared to the control group, but increased in the recovery group compared to the hypofunctional group. Conclusions: These findings suggest that root size and PDL structure may be reduced due to disuse atrophy resulting from a defect in occlusal function, but may be recovered following a gain of occlusal stimuli.

Effects of Different Angulation Placement of Mini-Implant in Orthodontic

2011 ◽  
Vol 121-126 ◽  
pp. 1214-1219 ◽  
Author(s):  
Aisyah Omar ◽  
Muhammad Ikman Ishak ◽  
Muhamad Noor Harun ◽  
Eshamsul Sulaiman ◽  
Noor Hayaty Abu Kasim
Keyword(s):  
Cortical Bone ◽  
Cancellous Bone ◽  
Orthodontic Treatment ◽  
3D Model ◽  
Three Dimensional ◽  
Von Mises Stress ◽  
Element Analysis ◽  
Optimal Angle ◽  
Second Molar ◽  
Molar Teeth

Orthodontic is one of the treatments in dentistry field which concerned on malocclusion treatments such as improper bites, tooth irregularity and disproportionate jaw relationships. The mini-implant (OMI) is one of the components used in the orthodontic treatment, besides braces and spring. The application of OMI has been well accepted in orthodontic treatment. However, one of the main factors of OMI failures is the implant insertion procedure in which the clinician find it difficult to obtain the best angle to insert the OMI. Therefore, this study aims to evaluate stress in an OMI and bones using the finite element analysis (FEA) with variations of insertion angles and to identify their optimal angle for the implant placement. The three dimensional (3D) model of a left maxillary posterior bone section was constructed based on CT image dataset. That 3D model consists of cortical bone, cancellous bone, second premolar, first molar and second molar teeth. The 3D model of OMI was placed between root of second premolar and first molar teeth. The OMI was simulated with seven different angles of insertions: 30˚, 40˚, 50˚, 60˚, 70˚, 80˚ and 90˚. Within the seven different insertion angles, the results showed that the increase of insertion angle reduced the maximum equivalent von Mises stress in cortical bone, cancellous bone and OMI. Based on this FEA study, the optimal angle placement of OMI is when the implant positioned at vertical angle (90˚) to the bone surface.

Metacarpal Cortical Bone Area Predicts Tooth Loss in Men

2016 ◽  
Vol 2 (2) ◽  
pp. 179-186 ◽  
Author(s):  
E.K. Kaye ◽  
P. Vokonas ◽  
R.I. Garcia
Keyword(s):  
Bone Loss ◽  
Cortical Bone ◽  
Tooth Loss ◽  
Alveolar Bone ◽  
Metacarpal Bone ◽  
Alveolar Bone Loss ◽  
Bone Area ◽  
Number Of Teeth

The relationship between bone mineral density and tooth loss in men is unclear. The aim of this retrospective cohort study was to determine if relative metacarpal bone area (MCA) predicts tooth loss in a cohort of 273 male participants in the Dental Longitudinal Study and Normative Aging Study of the Department of Veterans Affairs. Outer and inner cortical bone widths of the middle metacarpal of the nondominant hand were measured on anteroposterior hand radiographs approximately 11 y apart. Baseline MCA was computed and categorized into quartiles. The men were followed from 1971 to 2015. Incident tooth loss during 2 intervals was examined: concurrent with the MCA measurements and long term over the total follow-up (17 ± 7 y). Radiographic alveolar bone loss (ABL) was measured on periapical radiographs as a percentage of the distance from the cementoenamel junction to root apex, and the number of teeth with ABL >40% was computed. Negative binomial generalized linear regression models estimated the mean number of teeth with ABL >40% and the number lost (concurrent and total), controlling for age, smoking, number of teeth at baseline, percentage teeth with ≥1 decayed/filled surface, and years of follow-up. At baseline, MCA was inversely related to number of teeth with >40% ABL. Men in the lowest MCA quartile (Q1) lost the most teeth, both concurrent with MCA measurements and long term, but the association differed by caries level (≤55% or >55% decayed/filled teeth). At the low caries level, the numbers lost in Q1 were 29% greater than in the highest MCA quartile (Q4). At the high caries level, the numbers lost in Q1 were more than twice those in Q4. Associations were attenuated when further controlled for number of teeth with ABL>40%. These findings suggest that systemic bone status plays a role in tooth loss and that the association may be mediated by alveolar bone loss. Knowledge Transfer Statement: Low relative metacarpal bone area was related to loss of alveolar bone and incident tooth loss in men. This information extends previous research, primarily studies of women, showing that osteoporosis adversely affects oral health. Knowledge of a patient’s systemic bone status may be important for managing his or her periodontal disease. Tooth loss in the absence of periodontal inflammation may signify systemic bone loss. Interprofessional communication is central to maintaining optimal oral and bone health.

scholarly journals Mineralized bone loss at different sites in dialysis patients: implications for prevention.

1998 ◽  
Vol 9 (7) ◽  
pp. 1225-1233
Author(s):  
H C Schober ◽  
Z H Han ◽  
A J Foldes ◽  
M S Shih ◽  
D S Rao ◽  
...  
Keyword(s):  
Bone Loss ◽  
Cortical Bone ◽  
Bone Tissue ◽  
Cancellous Bone ◽  
Bone Volume ◽  
Ethnic Composition ◽  
Maintenance Hemodialysis ◽  
Appendicular Skeleton ◽  
Structural Abnormality ◽  
Patient Groups

To characterize the magnitude and location of mineralized bone loss, 40 patients (20 men, 20 women, 29 white, 11 black) with clinically significant renal osteodystrophy who could be unambiguously classified based on histologic criteria as having osteitis fibrosa (OF; 20 cases) or osteomalacia (OM; 20 cases) were studied; they had been on maintenance hemodialysis for 4.6 +/- 3.0 yr. One hundred forty-two healthy women of similar age and ethnic composition served as control subjects. In all subjects, the proportions of mineralized bone, osteoid, and porosity (nonbone soft tissue) were measured separately in cortical and cancellous bone tissue, from intact full-thickness biopsies of the ilium, representative of the axial skeleton. The results were related to the volumes of cortical and cancellous bone tissue separately and to the volume of the entire biopsy core. Approximately three-quarters of the patients had measurements in the appendicular skeleton by single photon absorptiometry of the radius and morphometry of the metacarpal. Disease effects did not differ significantly between ethnic groups. Mineralized cortical bone volume (per unit of core volume) was reduced by approximately 45% in both patient groups. Mineralized cancellous bone volume was significantly increased by 36% in the patients with OF and nonsignificantly reduced by 9% in the patients with OM; however, the reduction in the latter patients was significant in relation to tissue volume. The combined total deficit for both types of iliac bone was approximately 20% in the patients with OF and approximately 40% in the patients with OM. Significant reductions in appendicular cortical bone were demonstrated in both patient groups at both measurement sites. Regardless of the current histologic classification, the major structural abnormality in the skeleton is generalized thinning of cortical bone due to increased net endocortical resorption, the most characteristic effect on bone of hyperparathyroidism. Protection of the skeleton from the adverse consequences of renal failure will require therapeutic intervention in patients with no symptoms of either renal or bone disease.

scholarly journals Enhanced Biocompatibility of Multi-Layered, 3D Bio-Printed Artificial Vessels Composed of Autologous Mesenchymal Stem Cells

Polymers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 538 ◽  
Author(s):  
Eui Hwa Jang ◽  
Jung-Hwan Kim ◽  
Jun Hee Lee ◽  
Dae-Hyun Kim ◽  
Young-Nam Youn
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Acute Inflammation ◽  
Three Dimensional ◽  
Control Group ◽  
Porous Structures ◽  
Small Vessels ◽  
Clinical Tools ◽  
Autologous Mesenchymal Stem Cells

Artificial vessels capable of long-term patency are essential clinical tools in vascular surgery that involves small vessels. On-going attempts to develop artificial vessels that complements restenosis have not been entirely successful. Here, we report on the fabrication of small-sized artificial vessels using a three-dimensional bio-printer. The fabrication employed biodegradable polycaprolactone and autologous MSCs harvested from the bone-marrow of canines. The MSCs were cultured and differentiated into endothelial-like cells. After confirming differentiation, artificial vessels comprising three-layers were constructed and implanted into the arteries of canines. The autologous MSCs printed on artificial vessels (cell-derived group) maintained a 64.3% patency (9 of 14 grafts) compared with artificial vessels without cells (control group, 54.5% patency (6 of 11 grafts)). The cell-derived vessels (61.9 cells/mm2 ± 14.3) had more endothelial cells on their inner surfaces than the control vessels (21 cells/mm2 ± 11.3). Moreover, the control vessels showed acute inflammation on the porous structures of the implanted artificial vessels, whereas the cell-derived vessels exhibited fibrinous clots with little to no inflammation. We concluded that the minimal rejection of these artificial vessels by the immune system was due to the use of autologous MSCs. We anticipate that this study will be of value in the field of tissue-engineering in clinical practice.

scholarly journals Case Report: Postmortem bone histomorphometric analysis in a 38-year-old Japanese man with immobilization osteoporosis because of orthostatic hypotension related to amyloid light chain amyloidosis

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 479
Author(s):  
Masaki Hatano ◽  
Izuru Kitajima ◽  
Masaki Nakamura ◽  
Kazuya Isawa ◽  
Tatsuya Suwabe ◽  
...  
Keyword(s):  
Orthostatic Hypotension ◽  
Cortical Bone ◽  
Cancellous Bone ◽  
Light Chain ◽  
Bone Volume ◽  
Histomorphometric Analysis ◽  
Trabecular Thickness ◽  
Normal Value ◽  
Light Chain Amyloidosis ◽  
Bone Width

We performed a postmortem bone histomorphometric analysis of iliac bone on a 38-year-old man who had been bedridden for the nine months before his death because of orthostatic hypotension and severe malnutrition related to amyloidκ-light-chain amyloidosis. Cancellous bone volume was greatly decreased, with a trabecular bone volume to total bone volume ratio of 6.77% (normal value, 19.56% ± 5.62%). Trabecular thinning was also apparent, with a trabecular thickness of 78.9 μm (normal value, 131.3 ± 28.1 μm), although the trabecula was still preserved. Cortical bone width was normal, although areas of porosity area were clear throughout the cortical bone. Our findings indicate that immobilization-related osteoporosis may be closely associated with loss of cancellous bone.

Long-term treatment with sodium warfarin results in decreased femoral bone strength and cancellous bone volume in rats

2002 ◽  
Vol 105 (4) ◽  
pp. 353-358 ◽  
Author(s):  
Ryan R Simon ◽  
Suzanne M Beaudin ◽  
Marilyn Johnston ◽  
Kimberly J Walton ◽  
Stephen G Shaughnessy
Keyword(s):  
Bone Strength ◽  
Cancellous Bone ◽  
Term Treatment ◽  
Bone Volume ◽  
Femoral Bone ◽  
Long Term Treatment

scholarly journals Influence of Gastrectomy on Cortical and Cancellous Bones in Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Jun Iwamoto ◽  
Yoshihiro Sato ◽  
Hideo Matsumoto
Keyword(s):  
Bone Formation ◽  
Bone Mass ◽  
Cortical Bone ◽  
Cancellous Bone ◽  
Femoral Diaphysis ◽  
Control Group ◽  
Sham Operation ◽  
Sprague Dawley ◽  
Osteoid Surface ◽  
Cortical Bone Mass

The aim of the present study was to examine the influence of gastrectomy (GX) on cortical and cancellous bones in rats. Twenty male Sprague-Dawley rats were randomized into the two groups of 10 animals each: a sham operation (control) group and a GX group. Seven weeks after surgery, the bone mineral content and density (BMC and BMD, resp.) and the mechanical strength of the femur were determined, and bone histomorphometric analyses were performed on the tibia. GX induced decreases in the BMC, BMD, ultimate force, work to failure, and stiffness of the femoral distal metaphysis and the BMC, BMD, and ultimate force of the femoral diaphysis. GX induced a decrease in cancellous bone mass, characterized by an increased osteoid thickness, osteoid surface, osteoid volume, and bone formation. GX also induced a decrease in cortical bone mass, characterized by increased endocortical bone resorption. The GX induced reductions in the bone mass and strength parameters were greater in cancellous bone than in cortical bone. The present study showed that the response of bone formation, resorption, and osteoid parameters to GX and the degree of GX-induced osteopenia and the deterioration of bone strength appeared to differ between cortical and cancellous bones in rats.

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