scholarly journals The role of trauma and partner support in perinatal depression and parenting stress: An Australian pregnancy cohort study

2019 ◽  
Vol 65 (3) ◽  
pp. 225-234 ◽  
Author(s):  
Megan Galbally ◽  
Stuart J Watson ◽  
Philip Boyce ◽  
Andrew J Lewis
Keyword(s):  
Depressive Symptoms ◽  
Parenting Stress ◽  
Childhood Trauma ◽  
Perinatal Depression ◽  
Protective Role ◽  
Partner Support ◽  
History Of Childhood ◽  
History Of ◽  
The Relationship

Background: Improving our understanding of the relationship between maternal depression and parenting stress is likely to lie in the range of additional factors that are associated with vulnerability to depression and also to parenting stress. Objectives: To examine the role of trauma and partner support, in understanding the relationship between perinatal depression and parenting stress. Methods: This study utilises data from 246 women in a pregnancy cohort study that followed women from early pregnancy until their infant was 12 months. Included were both women with a diagnosis of depression and those without depression. The measures included Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Edinburgh Postnatal Depression Scale, Childhood Trauma Questionnaire, Social Support Effectiveness Questionnaire and the Parenting Stress Index. Results: We found women with depression were more likely to report a history of childhood trauma. Depressive symptoms were positively associated with parenting stress while partner support was negatively associated with parenting stress. The protective role of partner support for parenting distress was observed in those with no history of childhood abuse and low depressive symptoms, but not in those with a trauma history and high depressive symptoms. Conclusions: These findings highlight the importance of early trauma in understanding the protective role of support on the relationship between parenting and depression. These findings can inform future studies and the refinement of future interventions aimed at both perinatal depression and parenting.

Childhood trauma and being at-risk for psychosis are associated with higher peripheral endocannabinoids

2019 ◽  
Vol 50 (11) ◽  
pp. 1862-1871 ◽  
Author(s):  
E. Appiah-Kusi ◽  
R. Wilson ◽  
M. Colizzi ◽  
E. Foglia ◽  
E. Klamerus ◽  
...  
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
Childhood Trauma ◽  
Childhood Maltreatment ◽  
Peripheral Blood ◽  
Endocannabinoid System ◽  
History Of Childhood ◽  
Increased Risk ◽  
History Of

AbstractBackgroundEvidence has been accumulating regarding alterations in components of the endocannabinoid system in patients with psychosis. Of all the putative risk factors associated with psychosis, being at clinical high-risk for psychosis (CHR) has the strongest association with the onset of psychosis, and exposure to childhood trauma has been linked to an increased risk of development of psychotic disorder. We aimed to investigate whether being at-risk for psychosis and exposure to childhood trauma were associated with altered endocannabinoid levels.MethodWe compared 33 CHR participants with 58 healthy controls (HC) and collected information about previous exposure to childhood trauma as well as plasma samples to analyse endocannabinoid levels.ResultsIndividuals with both CHR and experience of childhood trauma had higher N-palmitoylethanolamine (p < 0.001) and anandamide (p < 0.001) levels in peripheral blood compared to HC and those with no childhood trauma. There was also a significant correlation between N-palmitoylethanolamine levels and symptoms as well as childhood trauma.ConclusionsOur results suggest an association between CHR and/or childhood maltreatment and elevated endocannabinoid levels in peripheral blood, with a greater alteration in those with both CHR status and history of childhood maltreatment compared to those with either of those risks alone. Furthermore, endocannabinoid levels increased linearly with the number of risk factors and elevated endocannabinoid levels correlated with the severity of CHR symptoms and extent of childhood maltreatment. Further studies in larger cohorts, employing longitudinal designs are needed to confirm these findings and delineate the precise role of endocannabinoid alterations in the pathophysiology of psychosis.

scholarly journals Depression across pregnancy and the postpartum, antidepressant use and the association with female sexual function

2018 ◽  
Vol 49 (09) ◽  
pp. 1490-1499 ◽  
Author(s):  
Megan Galbally ◽  
Stuart J. Watson ◽  
Michael Permezel ◽  
Andrew J. Lewis
Keyword(s):  
Depressive Symptoms ◽  
Childhood Trauma ◽  
Sexual Functioning ◽  
Perinatal Depression ◽  
Mode Of Delivery ◽  
Depression Scale ◽  
Partner Support ◽  
Antidepressant Use ◽  
Female Sexual Functioning ◽  
The Impact

AbstractBackgroundThere is an established relationship between depression and sexual functioning in women. However, there is limited research examining the relationship between perinatal depression and sexual functioning.MethodsThis study draws on the Mercy Pregnancy and Emotional Wellbeing Study and reports on 211 women recruited in early pregnancy and followed to 12 months postpartum. Women were assessed for depression using the Structured Clinical Interview for the DSM-IV, repeated measurement of depressive symptoms using the Edinburgh Postnatal Depression Scale and sexual functioning using the Female Sexual Functioning Inventory. Data were also collected on antidepressant use, mode of delivery, history of childhood trauma, breastfeeding and partner support.ResultsWomen showed a decline in sexual functioning over pregnancy and the first 6 months postpartum, which recovered by 12 months. For women with depression, sexual functioning was lower throughout pregnancy and continued to be lower at 6 months postpartum than those without depression. Ongoing depressive symptoms at 12 months were also associated with lower sexual functioning. Sexual functioning was not predicted by mode of delivery, antidepressant use or childhood trauma. Breastfeeding predicted lower sexual functioning only at 6 months. Higher partner support predicted higher female sexual functioning.ConclusionsPregnancy and the postpartum are a time of reduced sexual functioning for women; however, women with depression are more likely to have lower levels of sexual functioning and this was not predicted by antidepressant use. In women with perinatal depression, consideration of the impact on sexual functioning should be an integral part of care.

The relationship of childhood trauma and DNA methylation of NMDA receptor genes in first-episode schizophrenia

Epigenomics ◽  
2021 ◽  
Author(s):  
Camila M Loureiro ◽  
Helene A Fachim ◽  
Fabiana Corsi-Zuelli ◽  
Rosana Shuhama ◽  
Paulo R Menezes ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Childhood Trauma ◽  
Genomic Dna ◽  
First Episode ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
History Of ◽  
First Episode Schizophrenia ◽  
Relationship Of ◽  
The Relationship

Aim: We investigated GRIN1, GRIN2A, GRIN2B and LINE-1 DNA methylation in first-episode schizophrenia patients, their nonaffected siblings and age- and sex-matched controls testing for associations between DNA methylation and exposition to childhood trauma. Materials & methods: The Childhood Trauma Questionnaire evaluated the history of childhood trauma. Genomic DNA was bisulfite converted and pyrosequencing was employed to quantify DNA methylation. Results: GRIN2A, GRIN2B and LINE-1 DNA methylation was not associated with childhood trauma in patients, siblings and controls. Siblings with childhood trauma had hypermethylation at CpG1 of GRIN1 compared with siblings without trauma. Conclusion: Childhood trauma may influence GRIN1 methylation in subjects with liability to psychosis, but not in frank schizophrenia or controls.

scholarly journals Association between childhood trauma and multimodal early-onset hallucinations

2020 ◽  
Vol 216 (3) ◽  
pp. 156-158 ◽  
Author(s):  
François Medjkane ◽  
Charles-Edouard Notredame ◽  
Lucie Sharkey ◽  
Fabien D'Hondt ◽  
Guillaume Vaiva ◽  
...  
Keyword(s):  
Suicidal Ideation ◽  
Adverse Events ◽  
Childhood Trauma ◽  
Traumatic Experiences ◽  
History Of Childhood ◽  
Sensory Modalities ◽  
Icd 10 ◽  
History Of ◽  
The Relationship ◽  
Psychiatric Problems

SummaryPrevious reports suggest that adverse events during childhood could be related to an array of psychiatric problems. Here, we question the relationship between childhood traumatic experiences and the sensory complexity of hallucinations in a cohort of 75 children and adolescents. We evidence a positive link between the number of sensory modalities involved in hallucinations and history of childhood trauma, even after controlling for the co-occurrence of suicidal ideation or the number of ICD-10 diagnoses. These findings support initiatives in which a routine exploration of traumatic events in childhood is performed when multimodal hallucinations are present.

The relationship between childhood trauma and theory of mind in schizophrenia

2016 ◽  
Vol 33 (S1) ◽  
pp. s259-s259 ◽  
Author(s):  
J. Mrizak ◽  
R. Trabelsi ◽  
A. Arous ◽  
A. Aissa ◽  
H. Ben Ammar ◽  
...  
Keyword(s):  
Theory Of Mind ◽  
Childhood Trauma ◽  
Short Story ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
Neurocognitive Impairments ◽  
History Of ◽  
Physical Neglect ◽  
Competing Interest ◽  
The Relationship

IntroductionA history of childhood trauma is reportedly more prevalent in people suffering from psychosis than in the general population. Previous studies linked childhood trauma (CT) to neurocognitive impairments in schizophrenia (SCZ), but rarely to theory of mind (TOM) deficits.ObjectivesTo investigate the relationship between TOM deficits and CT in SCZ.MethodsFifty-eight outpatients with stable SCZ completed the Childhood Trauma Questionnaire retrospectively assessing five types of childhood trauma (emotional, physical and sexual abuse, and emotional and physical neglect). They also completed an intention-inferencing task, in which the ability to infer a character's intentions from information in a short story is assessed.ResultsOur results suggest a relationship between specific kinds of CT and TOM deficits. A history of childhood physical neglect was significantly correlated to a worse performance in the intention-inferencing task (P = 0,001). Patients with higher scores of CT denial also had less correct answers (P = 0,035) and more false answers (P = 0,013).ConclusionsOur results need replication but underline the necessity of investigating psychosocial mechanisms underlying the development of social cognition deficits, including deficits in TOM.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Mediating role of cognitive biases, resilience and depressive symptoms in the relationship between childhood trauma and psychotic‐like experiences in young adults

2019 ◽  
Vol 14 (1) ◽  
pp. 87-96 ◽  
Author(s):  
Dagmara Mętel ◽  
Aleksandra Arciszewska ◽  
Artur Daren ◽  
Renata Pionke ◽  
Andrzej Cechnicki ◽  
...  
Keyword(s):  
Young Adults ◽  
Depressive Symptoms ◽  
Childhood Trauma ◽  
Cognitive Biases ◽  
Mediating Role ◽  
The Relationship

Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders

2016 ◽  
Vol 47 (5) ◽  
pp. 902-912 ◽  
Author(s):  
M. Aas ◽  
C. Henry ◽  
F. Bellivier ◽  
M. Lajnef ◽  
S. Gard ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Childhood Trauma ◽  
Clinical Features ◽  
Suicide Attempts ◽  
Bipolar Disorders ◽  
History Of Childhood ◽  
History Of ◽  
Axis I ◽  
Affective Lability ◽  
The Relationship

BackgroundMany studies have shown associations between a history of childhood trauma and more severe or complex clinical features of bipolar disorders (BD), including suicide attempts and earlier illness onset. However, the psychopathological mechanisms underlying these associations are still unknown. Here, we investigated whether affective lability mediates the relationship between childhood trauma and the severe clinical features of BD.MethodA total of 342 participants with BD were recruited from France and Norway. Diagnosis and clinical characteristics were assessed using the Diagnostic Interview for Genetic Studies (DIGS) or the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). Affective lability was measured using the short form of the Affective Lability Scale (ALS-SF). A history of childhood trauma was assessed using the Childhood Trauma Questionnaire (CTQ). Mediation analyses were performed using the SPSSprocessmacro.ResultsUsing the mediation model and covariation for the lifetime number of major mood episodes, affective lability was found to statistically mediate the relationship between childhood trauma experiences and several clinical variables, including suicide attempts, mixed episodes and anxiety disorders. No significant mediation effects were found for rapid cycling or age at onset.ConclusionsOur data suggest that affective lability may represent a psychological dimension that mediates the association between childhood traumatic experiences and the risk of a more severe or complex clinical expression of BD.

scholarly journals Effect of Childhood Psychological Trauma on Mood and Neurotic Disorders: A Systematic Review

2021 ◽  
Vol 9 (12) ◽  
pp. 699-719
Author(s):  
Rohit Jaiswal
Keyword(s):  
Childhood Trauma ◽  
Age Groups ◽  
Psychological Trauma ◽  
Mental Illnesses ◽  
Research Papers ◽  
Neurotic Disorder ◽  
History Of Childhood ◽  
Neurotic Disorders ◽  
History Of ◽  
The Relationship

Abstract: Childhood trauma has been always associated with an increase in the prevalence of mental illnesses. Here, in this paper, we try to investigate and analyse different research papers to understand the relationship between childhood trauma and neurotic and mood disorders. We analysed more than 55 papers from the various sample populations which comprised various age groups. The results showed that childhood sexual and physical abuse is more prevalent in patients with depressive and anxiety disorders. Also, bipolar and neurotic excoriation patients had a history of childhood trauma. This concluded that childhood trauma can increase the risk of developing mood or neurotic disorders. Keywords: Childhood trauma, abuse, neurotic disorder and mood disorder.

Parenting Behaviors and Anxiety in Young Adults

2015 ◽  
Vol 36 (3) ◽  
pp. 170-176 ◽  
Author(s):  
Erin N. Stevens ◽  
Joseph R. Bardeen ◽  
Kyle W. Murdock
Keyword(s):  
Effortful Control ◽  
Parenting Behaviors ◽  
Protective Role ◽  
Anxiety Symptoms ◽  
Interactive Effects ◽  
Parental Overprotection ◽  
High Control ◽  
Development Of Anxiety ◽  
The Relationship

Parenting behaviors – specifically behaviors characterized by high control, intrusiveness, rejection, and overprotection – and effortful control have each been implicated in the development of anxiety pathology. However, little research has examined the protective role of effortful control in the relation between parenting and anxiety symptoms, specifically among adults. Thus, we sought to explore the unique and interactive effects of parenting and effortful control on anxiety among adults (N = 162). Results suggest that effortful control uniquely contributes to anxiety symptoms above and beyond that of any parenting behavior. Furthermore, effortful control acted as a moderator of the relationship between parental overprotection and anxiety, such that overprotection is associated with anxiety only in individuals with lower levels of effortful control. Implications for potential prevention and intervention efforts which specifically target effortful control are discussed. These findings underscore the importance of considering individual differences in self-regulatory abilities when examining associations between putative early-life risk factors, such as parenting, and anxiety symptoms.

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