scholarly journals Hybrid Knife, a Novel Drug Delivery Tool for Treatment of Tracheal Stenosis: A Case Report

2020 ◽  
pp. 014556132094664
Author(s):  
Yan Yin ◽  
Wen-hui Ma ◽  
Wei Li ◽  
Hai-feng Ma ◽  
Jian Kang ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
High Efficiency ◽  
Treatment Method ◽  
Subglottic Stenosis ◽  
Submucosal Layer ◽  
Topical Medication ◽  
Pressure Water ◽  
Technological Limitations ◽  
Novel Drug

The treatment of subglottic stenosis remains a challenge due to anatomic and technological limitations, and there is no consensus regarding treatment. Restenosis and granulation formation are the most common complications. Balloon dilatation combined with cryotherapy and adjuvant topical medication is one treatment method. However, the efficacy of adjuvant topical medication is controversial, and the lack of efficacy may be related to the effective dose of the drug delivered to the submucosal layer of the lesion. Therefore, a tool with high efficiency for delivering medications to the submucosal layer via injection may play an important role in treatment. A hybrid knife (HK) with a pressure water jet traditionally used in endoscopy submucosal dissection to inject saline into the submucosa was employed here to inject medications for subglottic stenosis, followed by electrical excision. Here, we report the case of a man with complex subglottic stenosis who underwent balloon dilatation combined with cryotherapy and an adjuvant submucosal triamcinolone injection performed with an HK. The drug was delivered more efficiently into the submucosal layer, and the lumen of the trachea was patent. Performing a submucosal injection with an HK may be a new approach to deliver medications to the submucosal layer for the treatment of tracheal stenosis.

scholarly journals Balloon tracheoplasty for tracheal stenosis after prolonged intubation: a simple procedure, but is it effective?

2021 ◽  
Vol 29 (1) ◽  
Author(s):  
Abdallah Nosair ◽  
Mahmoud Singer ◽  
Mohamed Elkahely ◽  
Rezk Abu-Gamila ◽  
Waleed Adel
Keyword(s):  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
Simple Procedure ◽  
Symptomatic Relief ◽  
Additional Treatment ◽  
Prolonged Intubation ◽  
Midterm Outcome ◽  
History Of ◽  
Balloon Tracheoplasty

Abstract Background Tracheal stenosis following prolonged intubation is a relatively rare but serious problem. This condition is usually managed by surgical or endoscopic interventions. Bronchoscopic balloon dilatation for tracheal stenosis is considered a valuable tool used for the management of tracheal stenosis. In this article, we try to evaluate the role of balloon tracheoplasty in the management of tracheal stenosis and to assess the number of dilatation sessions usually needed as well as the short to midterm outcome. Results This study involved 40 patients with tracheal stenosis diagnosed by computed tomography (neck and chest) and bronchoscopy at the Security Force Hospital in Riyadh, KSA, between January 2013 and August 2018. Patients’ data were retrospectively reviewed and analyzed. Patients’ age ranged between 18 and 60 years. Thirty patients were males (75%); those patients underwent balloon tracheoplasty via dilatation of areas of narrowing using catheter balloon insufflation guided by fiber-optic bronchoscope. Ninety-five percent of the patients had initial success with acceptable dilatation of the stenotic area and improvement of the symptoms. There were no technical or major problems which resulted from the procedure, and no patient complained of severe pain or severe discomfort after the procedure. From the total of 81 BBD sessions, no in-hospital mortality is related to the procedure itself, and ICU stay ranged between 1 and 5 days post-procedure. Among those 40 patients, 16 patients (40%) needed one session, 10 patients (25%) needed two sessions, 8 patients (20%) needed three sessions, and 6 patients (15%) needed more than three sessions of balloon dilatation. Conclusion Balloon tracheoplasty is a simple, safe method and could be a promising and effective approach that offers immediate symptomatic relief for tracheal stenosis in cases with a history of prolonged intubation. It is worth mentioning that BBD is considered as a temporary measure, and most of the cases will need definitive or additional treatment either resection or stent placement.

Idiopathic subglottic stenosis in a young female patient

2021 ◽  
Vol 14 (5) ◽  
pp. e241525
Author(s):  
Benjamin Pomerantz ◽  
Michael Pomerantz ◽  
Arkadiy Finn
Keyword(s):  
Balloon Dilatation ◽  
Young Female ◽  
Rigid Bronchoscopy ◽  
Pulmonary Function Testing ◽  
Subglottic Stenosis ◽  
Productive Cough ◽  
Shortness Of Breath ◽  
History Of ◽  
One Year ◽  
Function Testing

A previously healthy 30-year-old woman presented with 3 years of progressive shortness of breath and audible wheezing. One year prior to presentation, she developed a chronic non-productive cough. Pulmonary function testing revealed flattened inspiratory and expiratory peaks, characteristic of an extrathoracic fixed tracheal obstruction. Bronchoscopy confirmed subglottic stenosis (SGS). She had no history of intubation, tracheostomy or evidence of a systemic inflammatory illness. She was diagnosed with idiopathic SGS and referred for rigid bronchoscopy with balloon dilatation resulting in improvement in her symptoms.

scholarly journals Gold Extraction from Cyanidation Tailing Using Microwave Chlorination Roasting Method

Metals ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 1025 ◽  
Author(s):  
Fei Zhu ◽  
Libo Zhang ◽  
Haoyu Li ◽  
Shaohua Yin ◽  
Sivasankar Koppala ◽  
...  
Keyword(s):  
Microwave Field ◽  
High Efficiency ◽  
Chloride Concentration ◽  
Treatment Method ◽  
Gold Extraction ◽  
Microwave Roasting ◽  
Gold Mines ◽  
Chlorination Roasting ◽  
New Treatment ◽  
Gold Industry

At present, gold mines are increasingly scarce in the world. The yield of cyanidation tailing (CT) of refractory gold ores with a grade of 10 g/T is huge; however, the effective capitalization of the cyanidation tailing is a significant problem in the gold industry. In this work, a new treatment method, a microwave-roasting process developed. The effect of roasting temperature, calcium chloride concentration, holding time and mineral size on the recovery of Au researched under conventional and microwave conditions. It found that, under the same processing conditions, the Au recovery in the microwave field is much higher than that of conventional conditions. The preliminary reinforcing role of the microwave discussed in the recovery of gold. This might be because of the microwave absorption ability of CaCl2 is much better, heated quickly and the reactions intensified among CaCl2, O2, and H2O. As a result, the extraction of gold in CT drastically increased in the microwave field, and the microwave roasting technology shows the characteristics of environmental protection in terms of low energy consumption and high efficiency.

scholarly journals Therapeutic approach to children’s intussusception at late hospitalization

2003 ◽  
Vol 2 (2) ◽  
pp. 72-77
Author(s):  
M. K. Belyaev ◽  
K. K. Fyodorov
Keyword(s):  
Old Age ◽  
Therapeutic Approach ◽  
Pediatric Surgery ◽  
High Efficiency ◽  
Abdominal Cavity ◽  
Treatment Method ◽  
Time Period

The goal of the investigation was to define whether conservative disinvagination would be safe and effective for long children’s intussusception. 368 children of 1 month to 13 years old age with intussusception have been treated in Novokuznetsk’ pediatric surgery clinic for a period from 1976 up to 2001. The number of boys was 248 (67,4%) and girls — 120 (32,6%) respectively. Patients of the age up to 1 year old were 185 (50,3%), older than 1 year — 183 (49,7%). 214 patients (58,2%) were hospitalized during the first 12 hours from the disease began, 71 patients (19,3%) — during 12—24 hours, 48 patients (13%) — during 24—48 hours, 35 patients (9,5%) — after 48 hours. In our clinic the method of conservative intussusception therapy is considered to be the priority and its application, if there are no any abdominal cavity complications (peritonitis), does not depend on introducing form, patients’ age, time period of hospitalization following the disease or recurrence beginning. The bloodless therapy has been found to be effective: the 1th stage — 93,2%, the 2nd stage — 93%, the 3d stage — 86,4% and the 4th stage — 91,7%. Thus, our facts earnestly prove both the potential of bloodless intussusception treatment method for children at late hospitalization (after 24 hours) and its safety and high efficiency (88,3%).

scholarly journals Airway Management and Bronchoscopic Treatment of Subglottic and Tracheal Stenosis Using Holmium Laser with Balloon Dilatation

2018 ◽  
Vol 71 (S1) ◽  
pp. 453-458 ◽  
Author(s):  
Ashish Deshmukh ◽  
Sunil Jadhav ◽  
Virendra Wadgoankar ◽  
Unmesh Takalkar ◽  
Hafiz Deshmukh ◽  
...  
Keyword(s):  
Airway Management ◽  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
Holmium Laser

Comparison between traditional and small-diameter tube-assisted bronchoscopic balloon dilatation in the treatment of benign tracheal stenosis

2017 ◽  
Vol 12 (3) ◽  
pp. 1053-1060 ◽  
Author(s):  
Li-Hua Li ◽  
Yi-Lin Liang ◽  
Yu Li ◽  
Ming-Peng Xu ◽  
Wen-Tao Li ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
Small Diameter

scholarly journals Difficulty in tracheal extubation followed by tracheal collapse after balloon dilatation for tracheal stenosis therapy

Medicine ◽  
2018 ◽  
Vol 97 (22) ◽  
pp. e10907 ◽  
Author(s):  
Nana Li ◽  
Linjia Zhu ◽  
Jie Sun ◽  
Yinbing Pan ◽  
Mei Gao
Keyword(s):  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
Tracheal Extubation ◽  
Tracheal Collapse

Fluoroscopic-guided balloon dilatation and stenting in tracheal stenosis with metallic self-expandable stents and long-term follow-up results

2007 ◽  
Vol 51 (4) ◽  
pp. 351-357
Author(s):  
NK Bodhey ◽  
AK Gupta ◽  
KS Neelakandhan ◽  
PK Neema ◽  
TR Kapilamoorthy ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Balloon Dilatation ◽  
Long Term Follow Up

Mechanical Properties of Ultrafine-Grained Al-Mg Alloy Produced by Severe Plastic Deformation

2017 ◽  
Vol 743 ◽  
pp. 203-206 ◽  
Author(s):  
Alexander A. Kozulin ◽  
Vladimir A. Krasnoveikin ◽  
Vladimir A. Skripnyak ◽  
Evgeny N. Moskvichev ◽  
Valery E. Rubtsov
Keyword(s):  
Mechanical Properties ◽  
Plastic Deformation ◽  
Severe Plastic Deformation ◽  
High Efficiency ◽  
Physical And Mechanical Properties ◽  
Treatment Method ◽  
Mg Alloy ◽  
Complex Investigation ◽  
Angular Pressing ◽  
Ultrafine Grained

This study examines the effect of severe plastic deformation on the physical and mechanical properties of a light structural Al-Mg alloy. Severe plastic deformation has been performed by equal channel angular pressing through a die with an angle of 90° between the channels to produce ultrafine-grained structure in specimens of studied alloy. A complex investigation of the physical and mechanical properties of the processed alloy has been carried out to examine the microstructure and texture, and to measure microhardness, yield stress and ultimate tensile strength. The obtained results demonstrate high efficiency of the chosen treatment method and mode of producing a light ultrafine-grained alloy.

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