A Ternary Solution for Independent Acoustic Impedance and Speed of Sound Matching to Biological Tissues

1982 ◽  
Vol 4 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Jonathan Ophir ◽  
Paul Jaeger
Keyword(s):  
Speed Of Sound ◽  
Acoustic Impedance ◽  
Soft Tissues ◽  
Sound Propagation ◽  
Biological Tissues ◽  
Liquid System ◽  
The Body ◽  
Acoustic Parameters ◽  
Wide Range

In applications requiring a liquid which is acoustically well matched to biological tissues, it is often difficult to find a material which is matched well in terms of both the acoustic impedance and speed of sound propagation in it; changing one parameter invariably affects the other. A three component liquid system is described, which allows independent adjustment of these two acoustic parameters over a wide range. This range encompasses the soft tissues of the body. Results of parameter measurements are presented in the form which allows simple determination of the mixture required to match any combination of acoustic impedance and speed of sound propagation over a given range.

scholarly journals Large elastic deformations of isotropic materials. I. Fundamental concepts

1948 ◽  
Vol 240 (822) ◽  
pp. 459-490 ◽  
Keyword(s):  
The Body ◽  
Elastic Behaviour ◽  
Stress And Strain ◽  
Elastic Deformations ◽  
Hooke’S Law ◽  
Widespread Agreement ◽  
Wide Range ◽  
Hooke's Law ◽  
High Degree

The mathematical theory of small elastic deformations has been developed to a high degree of sophistication on certain fundamental assumptions regarding the stress-strain relationships which are obeyed by the materials considered. The relationships taken are, in effect, a generalization of Hooke’s law— ut tensio, sic vis . The justification for these assumptions lies in the widespread agreement of experiment with the predictions of the theory and in the interpretation of the elastic behaviour of the materials in terms of their known structure. The same factors have contributed to our appreciation of the limitations of these assumptions. The principal problems, which the theory seeks to solve, are the determination of the deformation which a body undergoes and the distribution of stresses in it, when certain forces are applied to it, and when certain points of the body are subjected to specified displacements. These problems are always dealt with on the assumption that the generalization of Hooke’s law is obeyed by the material of the body and that the deformation is small, i.e. the change of length, in any linear element in the material, is small compared with the length of the element in the undeformed state. Apart from the fact that the generalization of Hooke’s law is obeyed accurately by a very wide range of materials, under a considerable variety of stress and strain conditions, it has the further advantage that it leads to a mathematically tractable theory.

scholarly journals TECHNIQUE AND DEVICE FOR THE EXPERIMENTAL ESTIMATION OF THE ACOUSTIC IMPEDANCE OF VISCOELASTIC MEDIUM

2017 ◽  
Vol 8 (4) ◽  
pp. 314-326 ◽  
Author(s):  
O. V. Murav’eva ◽  
V. V. Murav’ev ◽  
D. V. Zlobin ◽  
O. P. Bogdan ◽  
V. N. Syakterev ◽  
...  
Keyword(s):  
Acoustic Impedance ◽  
Experimental Evaluation ◽  
Piezoelectric Element ◽  
Electric Circuit ◽  
Biological Tissues ◽  
Ultrasonic Waves ◽  
Acoustic Parameters ◽  
Laboratory Equipment ◽  
Viscoelastic Media ◽  
Silicone Sealant

Measuring the characteristics of process fluids allows us to evaluate their quality, biological tissues – to differentiate healthy tissues and tissues with pathologies. Measuring the characteristics of process fluids allows us to evaluate their quality, biological tissues – to differentiate healthy tissues and tissues with pathologies. One of the complex acoustic parameters is the impedance, which allows one to fully evaluate the characteristics of viscoelastic media. Most of impedance methods of measurements require using two or more reference media and the availability of calibrated acoustic transducers. The aim of this work ware introduced a methods and construction for the experimental evaluation of the longitudinal and shear impedance of viscoelastic media based on measuring the parameters of the amplitude-frequency characteristics and calculating the elements of the electric circuit for replacing the piezoelectric element which vibrating in the test medium.The paper introduces a methods and construction of the experimental evaluation of the impedances of viscoelastic media. The suggested methods is allowed measuring longitudinal and shear impedances and determining velocities of longitudinal and transverse ultrasonic waves and the values of the elastic moduli of viscoelastic media, including in various aggregate states. The technique is fairly simple to implement and can be reproduced using simple laboratory equipment.The obtained values of the acoustic impedances of the investigated media are in satisfactory agreement with their reference data. In contrast to the known methods for determining the acoustic impedance, the developed technique allows us to estimate with sufficient accuracy the parameter of the shear impedance of viscoelastic media that is difficult to measure at the frequencies of the megahertz range, which determines the shear modulus of the material and characterizes its resistance to shear deformations. The results of the implementation of the developed technique for the estimation of acoustic parameters for a number of media with zero shear elasticity (alcohol, acetone) and viscoelastic media (glycerin, architectural clay, silicone sealant and glue МР-55 before and after polymerization) are presented.

scholarly journals Constitutive modelling of arteries

2010 ◽  
Vol 466 (2118) ◽  
pp. 1551-1597 ◽  
Author(s):  
Gerhard A. Holzapfel ◽  
Ray W. Ogden
Keyword(s):  
Mechanical Behaviour ◽  
Soft Tissues ◽  
Elastic Strain Energy ◽  
Cylindrical Tube ◽  
Strain Energy Function ◽  
Biological Tissues ◽  
Constitutive Modelling ◽  
Highly Nonlinear ◽  
Wide Range ◽  
Modelling Effort

This review article is concerned with the mathematical modelling of the mechanical properties of the soft biological tissues that constitute the walls of arteries. Many important aspects of the mechanical behaviour of arterial tissue can be treated on the basis of elasticity theory, and the focus of the article is therefore on the constitutive modelling of the anisotropic and highly nonlinear elastic properties of the artery wall. The discussion focuses primarily on developments over the last decade based on the theory of deformation invariants, in particular invariants that in part capture structural aspects of the tissue, specifically the orientation of collagen fibres, the dispersion in the orientation, and the associated anisotropy of the material properties. The main features of the relevant theory are summarized briefly and particular forms of the elastic strain-energy function are discussed and then applied to an artery considered as a thick-walled circular cylindrical tube in order to illustrate its extension–inflation behaviour. The wide range of applications of the constitutive modelling framework to artery walls in both health and disease and to the other fibrous soft tissues is discussed in detail. Since the main modelling effort in the literature has been on the passive response of arteries, this is also the concern of the major part of this article. A section is nevertheless devoted to reviewing the limited literature within the continuum mechanics framework on the active response of artery walls, i.e. the mechanical behaviour associated with the activation of smooth muscle, a very important but also very challenging topic that requires substantial further development. A final section provides a brief summary of the current state of arterial wall mechanical modelling and points to key areas that need further modelling effort in order to improve understanding of the biomechanics and mechanobiology of arteries and other soft tissues, from the molecular, to the cellular, tissue and organ levels.

scholarly journals Ex-Vivo Exposure on Biological Tissues in the 2-μm Spectral Range with an All-Fiber Continuous-Wave Holmium Laser

Photonics ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 20
Author(s):  
Mariya S. Kopyeva ◽  
Serafima A. Filatova ◽  
Vladimir A. Kamynin ◽  
Anton I. Trikshev ◽  
Elizaveta I. Kozlikina ◽  
...  
Keyword(s):  
Solid State ◽  
Soft Tissues ◽  
Continuous Wave ◽  
Ex Vivo ◽  
Laser System ◽  
Biological Tissues ◽  
Holmium Laser ◽  
Experimental Point ◽  
Ablation Efficiency ◽  
Wide Range

We present the results on the interaction of an all-fiber Holmium-doped laser CW radiation at a wavelength of 2100 nm with soft tissues and compare it with the other results obtained by the most used solid-state laser systems. Ex-vivo single spot experiments were carried out on the porcine longissimus muscles by varying the laser impact parameters in a wide range (average output power 0.3, 0.5 and 1.1 W; exposure time 5, 30 and 60 s). Evaluation of the laser radiation exposure was carried out by the size of coagulation and ablation zones on the morphological study. Exposure to a power of 0.3 W (1.5–18 J of applied energy) caused only reversible changes in the tissues. The highest applied energy of 66 J for 1.1 W and a 60-s exposure resulted in a maximum ablation depth of approximately 1.2 mm, with an ablation efficiency of 35%. We have shown that it is not necessary to use high powers of CW radiation, such as 5–10 W in the solid-state systems to provide the destructive effects. Similar results can be achieved at lower powers using the simple all-fiber Holmium laser based on the standard single-mode fiber, which could provide higher power densities and be more convenient to manufacture and use. The obtained results may be valuable as an additional experimental point in the field of existing results, which in the future will allow one to create a simple optimal laser system for medical purposes.

scholarly journals Correcting the infrared images of soft biological tissues

2019 ◽  
Vol 55 (1) ◽  
pp. 110-117
Author(s):  
A. P. Ivanov
Keyword(s):  
Soft Tissues ◽  
Thermal Power ◽  
Spherical Shape ◽  
Biological Tissues ◽  
Thermal Source ◽  
Near Surface ◽  
Non Invasive ◽  
Calculation Results ◽  
Heat Transfer Parameter

Non-invasive (remote) thermographic methods based on IR images are being actively implemented. Using the calculation results of the temperature increment that occurs when a pathological source exists in the person’s skin, a number of ways of solving “inverse problems” are proposed. These include the determination of the depth of the thermal source by measuring the mono or polychrome increment of the normalized brightness of the tissue surface at one point; the source depth and heat transfer parameter by measuring the poly or monochrome one of the normalized brightness (or temperature) at two points; the thermal power of the source by measuring the increment of absolute brightness or temperature at one point; the depth of the thermal source and its size in the near-surface layer by measuring the increment of the normalized brightness at two points. In order to solve these problems, the thermophysical and optical properties of the soft tissues of the biological organism are indicated. Analytical solutions are given for describing the temperature and the glow that arises under its influence from the sources of cylindrical and spherical shape.

scholarly journals A focus on homocysteine in autism.

2013 ◽  
Vol 60 (2) ◽  
Author(s):  
Joanna Kałużna-Czaplińska ◽  
Ewa Żurawicz ◽  
Monika Michalska ◽  
Jacek Rynkowski
Keyword(s):  
Human Physiology ◽  
Folic Acid ◽  
Dietary Habits ◽  
Biological Fluids ◽  
Body Fluids ◽  
The Body ◽  
Autistic Children ◽  
Pathological Conditions ◽  
Wide Range

Homocysteine is an amino acid, which plays several important roles in human physiology. A wide range of disorders, including neuropsychiatric disorders and autism, are associated with increased homocysteine levels in biological fluids. Various B vitamins: B6 (pyridoxine), B12 (cobalamin), and B9 (folic acid) are required as co-factors by the enzymes involved in homocysteine metabolism. Therefore, monitoring of homocysteine levels in body fluids of autistic children can provide information on genetic and physiological diseases, improper lifestyle (including dietary habits), as well as a variety of pathological conditions. This review presents information on homocysteine metabolism, determination of homocysteine in biological fluids, and shows abnormalities in the levels of homocysteine in the body fluids of autistic children.

Simple shearing of soft biological tissues

2010 ◽  
Vol 467 (2127) ◽  
pp. 760-777 ◽  
Author(s):  
Cornelius O. Horgan ◽  
Jeremiah G. Murphy
Keyword(s):  
Simple Shear ◽  
Soft Tissues ◽  
Hydrostatic Stress ◽  
Biological Tissues ◽  
Soft Biological Tissues ◽  
Hyperelastic Materials ◽  
Pressure Term ◽  
Deformation State ◽  
Hydrostatic Stresses

Shearing is induced in soft tissues in numerous physiological settings. The limited experimental data available suggest that a severe strain-stiffening effect occurs in the shear stress when soft biological tissues are subjected to simple shear in certain directions. This occurs at relatively small amounts of shear (when compared with the simple shear of rubbers). This effect is modelled within the framework of nonlinear elasticity by consideration of a class of incompressible anisotropic materials. Owing to the large stresses generated for relatively small amounts of shear, particular care must be exercised in order to maintain a homogeneous deformation state in the bulk of the specimen. The results obtained are relevant to the development of accurate shear test protocols for the determination of constitutive properties of soft tissues. It is also demonstrated that there is a fundamental ambiguity in determining the normal stresses in simple shear when soft tissues are modelled as incompressible hyperelastic materials owing to the arbitrary nature of the hydrostatic pressure term. Two physically well-motivated approaches to determining the pressure are presented here, and the resulting hydrostatic stresses are compared and contrasted. The possible generation of cavitational damage owing to critical hydrostatic stress levels is briefly discussed.

scholarly journals RESEARCH OF THE RELATIONSHIP OF THE RATE OF ULTRASOUND IN METALS WITH THEIR IMPACT VISCOSITY AND HARDNESS UNDER THE CONDITIONS OF REDUCED TEMPERATURES

2020 ◽  
pp. 60-67
Author(s):  
Alexander A. Khlybov ◽  
Yuri G. Kabaldin ◽  
Maksim S. Anosov ◽  
Dmitry A. Ryabov ◽  
Yuri I. Matveev
Keyword(s):  
Impact Toughness ◽  
Longitudinal Wave ◽  
Speed Of Sound ◽  
Low Temperatures ◽  
Sound Propagation ◽  
Close Correlation ◽  
Wide Range ◽  
Velocity Of Propagation ◽  
Relationship Of ◽  
The Relationship

The paper presents the results of the study of the relationship between the velocity of propagation of longitudinal waves in a metal with the values ​​of impact toughness and hardness in a wide range of low temperatures. It’s been found that with a decrease of temperature, an increase of hardness, a decrease of impact toughness and an increase of the velocity of propagation of a longitudinal wave in the studied metals are observed, and the velocity of propagation of a longitudinal wave has a close correlation with the characteristics under consideration. An increase of the speed of sound with decreasing temperature, in our opinion, is explained by an increase of the thermal conductivity of metals. Thus, by the values ​​of the speed of sound propagation in metals, it is possible to predict the level of its impact toughness, as well as hardness at low temperatures, and, consequently, the tendency to brittle fracture of structures.

Electron Heat Transfer in a Quiescent Nonequilibrium Plasma

1970 ◽  
Vol 92 (3) ◽  
pp. 447-455 ◽  
Author(s):  
E. V. McAssey ◽  
Hsuan Yeh
Keyword(s):  
Heat Transfer ◽  
Nonequilibrium Plasma ◽  
Spherical Body ◽  
Operating Conditions ◽  
The Body ◽  
Electron Heat ◽  
Wide Range ◽  
Weakly Ionized ◽  
Body Potential

An asymptotic solution has been obtained for the electron heat transfer to a spherical body immersed in a weakly ionized, quiescent plasma. Dimensional analysis of the governing equations shows that the problem can be divided into two regions: charge-separated and quasi-neutral. For the charge-separated region, the equations must be solved numerically, whereas the quasi-neutral solution can be expressed in closed form. From these studies it was found that the extent of the charge-separated region (i.e, sheath) is of the order of Λ2/3. Within the sheath the effects of ionization and recombination are of the order of Λ4/3. The results include the variation of electron flux, electron heat transfer, and current as a function of body potential. The results are presented in a form to permit the easy determination of the electron heat transfer to a body immersed in a quiescent, weakly ionized plasma over a wide range of operating conditions. Furthermore, the electrical characteristics presented here can be used in conjunction with electron heating data to treat the body as a probe for diagnostic purposes.

Effect of highly porous bioceramics based on ZrO2 – Y2O3 – CeO2 system on the biological tissues of experimental animals

2020 ◽  
pp. 29-39
Author(s):  
M. V. Kalinina ◽  
◽  
N. Yu. Kovalko ◽  
D. N. Suslov ◽  
Yu. S. Andozhskaia ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Pore Space ◽  
Biological Tissues ◽  
The Body ◽  
Laboratory Animals ◽  
Experimental Animals ◽  
Average Grain Size ◽  
Porous Bioceramics ◽  
Highly Porous

By reverse co-deposition of hydroxides synthesized highly dispersed powder (the average size 8 – 10 nm) of the composition (ZrO2)0.92(Y2О3)0.03(СеО2)0.05, based on it use comprehensive a blowing agent and mechanical activation of the obtained highly porous ceramics (average grain size 60 – 65 nm). The synthesized ceramic material-an implant with an open porosity of 55 % and a pore size of 40 – 800 nm was placed in the body of laboratory animals. The reaction of biological tissues of experimental animals to the introduction of plates made of composite highly porous materials based on t-ZrO2 15 months after their implantation was studied. It is revealed that enhanced revascularization is registered in capsules, and perfusion of tissues is registered in intact zone of ceramics introduction. The possibility of germination of vessels in soft tissues into the available pore space of ceramics is shown. The results obtained in vivo suggest that porous bioceramics based on t-ZrO2 can be used in the production of endoprostheses and implants in such areas of medicine as orthopedics and traumatology.

Sign in / Sign up

Export Citation Format

Share Document