scholarly journals Olecranon metastases from primary lung cancer: case report and review of the literature

2019 ◽  
Vol 47 (10) ◽  
pp. 5312-5317
Author(s):  
Leyi Cai ◽  
Shuangxia Dong ◽  
Hua Chen
Keyword(s):  
Soft Tissue Mass ◽  
Primary Lung Cancer ◽  
Cancer Case ◽  
Computed Tomography Imaging ◽  
Distal Ulna ◽  
Tissue Mass ◽  
Poorly Differentiated Adenocarcinoma ◽  
History Of ◽  
Poorly Differentiated ◽  
History Of Pain

Tumours in the olecranon are rare. A 62-year-old man presented with a 3-week history of pain in his right elbow that was relieved using routine painkillers. Persistent pain resulted in a reduction of the range of motion in the elbow and pain in the extensor and flexor groups of muscles of the forearm, which resulted in the patient seeking medical assistance. Radiography showed a round, radiolucent focus in the depth of the distal ulna. Computed tomography imaging of the thorax demonstrated one solid soft tissue mass. Histological investigation showed the cancer was a poorly differentiated adenocarcinoma. The patient received local radiotherapy and systemic chemotherapy, but he died of his primary disease 3 months later.

scholarly journals Thymoma in an aged backyard Leghorn chicken, with reviews of a database and literature

2021 ◽  
Vol 33 (2) ◽  
pp. 336-339
Author(s):  
Julia Blakey ◽  
Carmen Jerry ◽  
Ana da Silva ◽  
Simone Stoute
Keyword(s):  
Soft Tissue Mass ◽  
Animal Health ◽  
Postmortem Examination ◽  
Cervical Region ◽  
Laboratory System ◽  
Unexpected Death ◽  
Tissue Mass ◽  
Microscopic Features ◽  
History Of ◽  
Backyard Chickens

A 7-y-old backyard Leghorn chicken ( Gallus domesticus) was submitted to the California Animal Health and Food Safety Laboratory System (CAHFS)–Turlock branch for postmortem examination, with a history of unexpected death. At postmortem examination, a hemorrhagic soft tissue mass was observed in the cervical region. Microscopically, a densely cellular neoplasm of polygonal epithelial cells and small lymphocytes was observed. The microscopic features of the neoplasm in combination with positive immunohistochemistry for pancytokeratin and CD3 were used to classify the lesion as a thymoma. Thymoma was diagnosed in only 5 birds submitted to CAHFS from 1990 to 2019. Thymoma has been described only rarely in birds, and is an unusual diagnosis in backyard chickens.

Dedifferentiated Liposarcoma With a Paraganglioma-like Histologic Pattern: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (7) ◽  
pp. 788-791
Author(s):  
Dating Liu ◽  
Guillermo Quinonez ◽  
Steven Latosinsky
Keyword(s):  
Neuron Specific Enolase ◽  
Malignant Neoplasm ◽  
Neuroendocrine Differentiation ◽  
Growth Patterns ◽  
Dedifferentiated Liposarcoma ◽  
Tissue Mass ◽  
Histologic Pattern ◽  
History Of ◽  
Poorly Differentiated ◽  
Well Differentiated

Abstract A 53-year-old man presented with a 4-month history of increasing abdominal discomfort and distension. A large retroperitoneal mass was found on imaging. Image-guided needle core biopsy demonstrated a poorly differentiated malignant neoplasm. A 30 × 32 × 33-cm soft tissue mass was removed. Microscopically, the tumor consisted of predominantly epithelioid malignant cells arranged in a paraganglioma-like growth pattern. Immunohistochemically, these cells were strongly positive for neuron-specific enolase. Stains for synaptophysin and chromogranin, however, were negative. There was no ultrastructural evidence of neuroendocrine differentiation. Adjacent sarcomatous areas were composed of spindled cells arranged in storiform and fibrosarcoma-like growth patterns. A small area of well-differentiated liposarcoma was identified, and a diagnosis of dedifferentiated liposarcoma was established. To the best of our knowledge, this represents the first reported case of dedifferentiated liposarcoma with a paraganglioma-like histologic pattern. A brief review focusing on the morphologic variations of dedifferentiated liposarcoma is also presented.

Poorly Differentiated Chordomas Showing Loss of INI1/SMARCB1: A Report of 2 Rare Cases With Diagnostic Implications

2018 ◽  
Vol 26 (7) ◽  
pp. 637-643 ◽  
Author(s):  
Bharat Rekhi ◽  
Kemal Kosemehmetoglu ◽  
Swapnil Rane ◽  
Figen Soylemezoglu ◽  
Elif Bulut
Keyword(s):  
Soft Tissue ◽  
Tumor Cells ◽  
Soft Tissue Mass ◽  
Head Movements ◽  
Cervical Region ◽  
Tissue Mass ◽  
First Case ◽  
Radiologic Imaging ◽  
Poorly Differentiated ◽  
Mitotic Figures

Poorly differentiated chordomas are rare musculoskeletal tumors. Case 1. A 42-year-old lady presented with quadriparesis of 2 months’ duration. Radiologic imaging disclosed a soft tissue mass in her left prevertebral- and paravertebral cervical region. Case 2. A 4-year-old male child presented with neck pain and restricted head movements of 1-year duration. Radiologic imaging revealed a contrast enhancing, paraspinal soft tissue mass in his cervical region. Microscopic examination in both the cases revealed a cellular malignant tumor composed of moderate to markedly pleomorphic cells with interspersed mitotic figures, along with focal myxoid change and necrosis. By immunohistochemistry, tumor cells in both cases were diffusely positive for pan cytokeratin (AE1/AE3) and brachyury, whereas these were negative for INI1/SMARCB1. Tumor cells in the second case were also positive for glypican3. The first case developed pulmonary metastasis, while the second case developed recurrence. Poorly differentiated chordomas are uncommon tumors, invariably characterized by loss of INI1. These tumors can be rarely seen in adults and need to be differentiated from their diagnostic mimics, in view of treatment implications and their relatively aggressive clinical outcomes.

Intramuscular Haemangioma of the Extensor Pollicis Brevis Muscle with Periosteal Reaction of the Radius: A Case Report and Review of the Literature

2007 ◽  
Vol 35 (5) ◽  
pp. 724-730 ◽  
Author(s):  
EH Kayias ◽  
GI Drosos ◽  
KI Kazakos ◽  
C Iatrou ◽  
KS Blatsoukas ◽  
...  
Keyword(s):  
Current Knowledge ◽  
Periosteal Reaction ◽  
Review Of The Literature ◽  
Tissue Mass ◽  
Bone Changes ◽  
History Of ◽  
Intramuscular Haemangioma ◽  
History Of Pain ◽  
The Right

We report the rare case of a histologically proven mixed-type intramuscular haemangioma, adjacent to the periosteum of the radius, that caused a periosteal reaction. We also carried out a review of the literature relevant to this case. A 28-year-old male professional drummer presented with an 8-month history of pain and swelling of the dorsal aspect of the right radius. Diagnosis was established on the basis of plain radiographs and magnetic resonance imaging, and was confirmed by histology. The lesion was treated solely by resection of the soft-tissue mass. The patient remained asymptomatic 4 years post-operatively, with no radiographic signs of recurrence. From a review of the literature, it is evident that the terminology for haemangiomas causing regional bone changes is unclear. A new classification of the intramuscular haemangiomas is proposed in order to distinguish between lesions that, according to current knowledge, exhibit radiological and clinical areas of overlap.

Vulval myxoid liposarcoma

2001 ◽  
Vol 11 (4) ◽  
pp. 321-322 ◽  
Author(s):  
R. Donnellan ◽  
M. Moodley
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Lymph Nodes ◽  
Soft Tissue Mass ◽  
Myxoid Liposarcoma ◽  
Complete Resection ◽  
Tissue Mass ◽  
History Of ◽  
Labium Majus ◽  
Draining Lymph Nodes

Abstract.Donnellan R, Moodley M. Vulval myxoid liposarcoma.A 26 year old woman presented with a 4-year history of a gradually enlarging fluctuant mass on the left labium majus. Histologic examination following excision revealed myxoid liposarcoma. Following the diagnosis, further surgery was performed to ensure complete resection. Routine excision of draining lymph nodes is not advocated. Although rare, myxoid liposarcoma should be considered in the differential diagnosis of a vulval soft tissue mass.

Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm

2021 ◽  
Vol 14 (2) ◽  
pp. e236856
Author(s):  
Susruta Manivannan ◽  
Feras Sharouf ◽  
George Lammie ◽  
Paul Leach
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Neuroendocrine Tumour ◽  
Clinical Findings ◽  
Neuroendocrine Neoplasm ◽  
Tumour Resection ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Left Hand ◽  
History Of

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

scholarly journals A case of Synchronous Malignancy of Stomach and Kidney

2014 ◽  
Vol 11 (1) ◽  
pp. 94-95 ◽  
Author(s):  
S SM Aslam ◽  
H Sridhar ◽  
MY Rao
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Left Kidney ◽  
Poorly Differentiated Adenocarcinoma ◽  
Primary Renal Cell Carcinoma ◽  
History Of ◽  
Poorly Differentiated ◽  
Polypoidal Growth ◽  
Synchronous Malignancy

The synchronous occurrence of primary renal cell carcinoma with gastric cancer is very rare. We report a case of 41 year old male who presented on 05/07/2011 to M S Ramaiah hospital, Bangalore with history of fever, pain abdomen and malena. Ultrasound abdomen and pelvis showed large heterogenous mass arising from the upper pole of left kidney. Computed tomography of the abdomen showed left renal cell carcinoma. Renal biopsy showed features consistent with renal cell carcinoma – clear cell type. Oesophagogastroduodenoscopy revealed gastric polypoidal growth. Gastric biopsy from the growth revealed poorly differentiated adenocarcinoma of stomach. We report this case to highlight a rare occurrence of synchronous malignancy of stomach and kidney. DOI: http://dx.doi.org/10.3126/kumj.v11i1.11053 Kathmandu University Medical Journal Vol.11(1) 2013: 94-95

scholarly journals Alfa-Fetoprotein-Producing Female Primary Urethral Adenocarcinoma with Neuroendocrine Differentiation

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Takao Natsuyama ◽  
Yozo Mitsui ◽  
Masato Uetani ◽  
Shigeyuki Ohta ◽  
Masafumi Inoue ◽  
...  
Keyword(s):  
Bladder Neck ◽  
Ileal Conduit ◽  
Neuroendocrine Differentiation ◽  
Urinary Frequency ◽  
Normal Range ◽  
Poorly Differentiated Adenocarcinoma ◽  
History Of ◽  
Poorly Differentiated ◽  
Proximal Urethra ◽  
Enhanced Computed Tomography

We report an extremely rare case of an alpha-fetoprotein- (AFP-) producing female primary urethral adenocarcinoma with neuroendocrine differentiation (NED). The patient was a 65-year-old woman with a 2-year history of urinary frequency and voiding difficulty. Enhanced computed tomography showed an approximately 3.0×5.0-cm mass around the proximal urethra and bladder neck. Of examined tumor markers, serum AFP was elevated (48.3 ng/mL), while others including carcinoembryonic antigen were within a normal range. Transurethral resection of the tumor led to a diagnosis of carcinosarcoma of the urethra, with a radical cystourethrectomy and ileal conduit formation subsequently performed. The pathological assessment was poorly differentiated adenocarcinoma in the urethra. Immunostaining showed tumor cells strongly positive for AFP. In addition, some cancer cells were positive for CD56, chromogranin A, and synaptophysin, indicating focal NED. The tumor was finally diagnosed as an AFP-producing urethral adenocarcinoma with NED. Serum AFP was immediately normalized after surgery and no sign of tumor recurrence has been noted 2 years postoperatively.

Olfactory ganglioneuroblastoma in a dog: case report and literature review

2021 ◽  
pp. 104063872110228
Author(s):  
Ashley M. Romano ◽  
Chad B. Frank
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Ganglion Cells ◽  
Soft Tissue Mass ◽  
Neoplastic Cell ◽  
Cell Populations ◽  
Intact Male ◽  
Tissue Mass ◽  
Immunohistochemical Markers ◽  
History Of

A 7-y-old, intact male Alaskan Malamute was presented with a 3-mo history of stertor and epistaxis. Computed tomography of the skull revealed generalized loss of gas throughout both nasal passages with replacement by a soft tissue mass that traversed the cribriform plate. Histopathology revealed neoplastic neuroblast cells arranged in anastomosing cords, as well as separately located aggregates of ganglion cells. Both neoplastic cell populations demonstrated immunoreactivity to MAP-2, TuJ-1, and synaptophysin. Neuroblastic cells additionally exhibited punctate immunoreactivity to MCK and CK8/18. We document here both the positive neural immunohistochemical markers for this neoplasm, as well as propose possible histomorphologic variants.

scholarly journals A Case Report of Carbohydrate Antigen 19-9 Producing Advanced Gastric Cancer

2016 ◽  
Vol 5 (2) ◽  
pp. 49
Author(s):  
Konomi Mizuguchi ◽  
Koichi Sato ◽  
Hiroshi Maekawa ◽  
Mutsumi Sakurada ◽  
Hajime Orita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Carbohydrate Antigen ◽  
Cancer Case ◽  
Gastric Cancer Case ◽  
Poorly Differentiated Adenocarcinoma ◽  
Epigastric Discomfort ◽  
Aortic Lymph Node ◽  
Poorly Differentiated ◽  
High Level

<p class="cco-body"><span lang="EN-GB">The gastric cancer producing carbohydrate antigen 19-9 (CA 19-9) is a rare and unknown that characterize informations.</span></p><p class="cco-body"><span lang="EN-GB">74-year-old woman who was admitted with complaints of epigastric discomfort. An advanced cancer was found in her lower gastric region; biopsy of the tumor revealed poorly-differentiated adenocarcinoma. Her serum CA 19-9 was extremely elevated at 2322 U/ml and computed tomography demonstrated enlargement of the para-aortic lymph node; thus the tumor was considered unresectable. The patient received 8 cycles of chemotherapy with S-1/cisplatin, which shrank the para-aortic lymph node dramatically, hence she underwent D2 gastrectomy. Immunohistochemical staining of the resected cancer revealed that a third of the cancer cells were positive for CA 19-9. In addition, her serum CA 19-9 decreased rapidly after surgery and she remains alive without recurrence three years after surgery.</span></p><p class="cco-body"><span lang="EN-GB">We report one high level of CA 19-9 gastric cancer case with dramatically chemosensitive.</span></p>

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