Non-Pharmacological Factors in Drug Therapy—The Inter-Action of Doctor, Patient and Tablet Appearance in the Treatment of Anxiety/Depressive Syndromes

1975 ◽  
Vol 3 (2) ◽  
pp. 125-133 ◽  
Author(s):  
A A Schiff ◽  
J E Murphy ◽  
J A Anderson

The degree to which placebo response is involved in an active treatment situation in normal clinical practice, and the factors comprising the placebo response, have been analyzed in a study on patients with anxiety/depressive syndromes. Four tablet preparations of different appearance but identical pharmacological activity were used over a three week period, and a comparison of therapeutic benefits between ‘treatments', doctors, and doctor—patient groupings was made, in addition to an analysis of the relationship of patients' self-assessments with their physicians' ratings. The results showed that although direct pharmacological effect was paramount in determining therapeutic outcome, detailed differences were related to various placebo factors. The similarity between physicians' and patients' ratings tends to decrease during the course of treatment, and possible reasons for this are reviewed in the light of previous work.

Ramus ◽  
2007 ◽  
Vol 36 (1) ◽  
pp. 25-38 ◽  
Author(s):  
Myles Lavan

(BJ6.350)Those who discard their weapons and surrender their persons, I will let live. Like a lenient master in a household, I will punish the incorrigible but preserve the rest for myself.So ends Titus' address to the embattled defenders of Jerusalem in the sixth book of Josephus'Jewish War(6.328-50). It is the most substantial instance of communication between Romans and Jews in the work. Titus compares himself to the master of a household and the Jewish rebels to his slaves. Is this how we expect a Roman to describe empire? If not, what does it mean for our understanding of the politics of Josephus' history? The question is particularly acute given that this is not just any Roman but Titus himself: heir apparent and, if we believe Josephus, the man who read and approved this historical account. It is thus surprising that, while the speeches of Jewish advocates of submission to Rome such as Agrippa II (2.345-401) and Josephus himself (5.362-419) have long fascinated readers, Titus' speech has received little or no attention. Remarkably, it is not mentioned in any of three recent collections of essays on Josephus. This paper aims to highlight the rhetorical choices that Josephus has made in constructing this voice for Titus—particularly his self-presentation as master—and the interpretive questions these raise for his readers. It should go without saying that the relationship of this text to anything that Titus may have said during the siege is highly problematic. (Potentially more significant, but unfortunately no less speculative, is the question of how it might relate to any speech recorded in the commentaries of Vespasian and Titus that Josephus appears to have used as a source.) What we have is a Josephan composition that is embedded in the broader narrative of theJewish War.


Author(s):  
Jonathan Kimmelman

Many representations of clinical translation present it as a linear process by which bench discoveries are advanced into clinical practice. The present chapter offers a conceptual framework that highlights distinctive ethical aspects of clinical translation. The framework understands clinical translation as a process not so much as developing new treatments but rather generating evidence on how to use (and how not to use) new as well as old interventions. It also emphasizes attending to the relationship of different studies with each other and the importance of coordinating different studies with each other. The model presented here foregrounds the role of coordination in realizing societal objectives of clinical translation at minimal burden and cost for patients and study volunteers.


2013 ◽  
Vol 12 (1) ◽  
pp. 112-132
Author(s):  
Paul Avis

AbstractHow can we explain the fact that the Anglican Covenant divides people of equal integrity and comparable wisdom around the world? We need to ask whether we have correctly understood both the ecclesiology of the Anglican Communion and the terms of the Covenant. What is implied in being a Communion of Churches, where the churches are the subjects of the relationship of communion (koinonia)? What does the Covenant commit its signatories to and, in particular, what does it say about doctrinal and ethical criteria for communion? Is it legitimate to apply biblical covenant language, in which the covenant relationship is between God and Israel, to relations between churches? By addressing some of the concerns of those who oppose it, a case is made in favour of the Covenant and some reassurances are offered. In conclusion, the mystical dimension of being in communion is affirmed.


2019 ◽  
Vol 26 (2) ◽  
pp. 911-924
Author(s):  
Mark J Rapoport ◽  
Carla Zucchero Sarracini ◽  
Benoit M Mulsant ◽  
Dallas P Seitz ◽  
Frank Molnar ◽  
...  

Clinicians face challenges in deciding which older patients with dementia to report to transportation administrators. This study used a qualitative thematic analysis to understand the utility and limitations of implementing a computer-based Driving in Dementia Decision Tool in clinical practice. Thirteen physicians and eight nurse practitioners participated in an interview to discuss their experience using the tool. While many participants felt the tool provided a useful ‘virtual second opinion’, specialist physicians felt that the tool did not add value to their clinical practice. Barriers to using the Driving in Dementia Decision Tool included lack of integration with electronic medical records and inability to capture certain contextual nuances. Opinions varied about the impact of the tool on the relationship of clinicians with patients and their families. The Driving in Dementia Decision Tool was judged most useful by nurse practitioners and least useful by specialist physicians. This work highlights the importance of tailoring knowledge translation interventions to particular practices.


2019 ◽  
Vol 91 (12) ◽  
pp. 75-83
Author(s):  
V V Fomin ◽  
T E Morosova ◽  
V V Tsurko

In recent years, the relationship of hyperuricemia and gout with a high risk of cardiovascular disease has been widely discussed. Therefore, it is important to systematically examine patients in order to diagnose comorbidities, among which cardiovascular disease and its complications occupy a leading place and consider mandatory treatment of patients with hyperuricemia and gout with high cardiovascular risk with lowering drugs, which fully reflects the provisions of the latest European recommendations for the management and treatment of patients with gout.


2017 ◽  
Vol 1 (2) ◽  
pp. 85-92
Author(s):  
Maya Sofiyani ◽  
M Imron Mawardi ◽  
P Sigit Purnomo ◽  
Hariza Adnani

The effort of leptospirosis prevention in Sleman currently only limited to counseling and treatment of the patient, while the patient search, ways of transmission of leptospirosis from rats to humans, have never implemented in an integrated manner. The study aimed to investigated the relationship between the environmental residential condition with the risk of leptospirosis in Sleman Regency. The research used a survey method  with case control study design. The results showed that environmental factors, which are not proved to have a relationship with the risk of leptospirosis were residential condition ({p=0,108} OR=3,818 {95%CI:0,922–15,811}), the trash bin condition ({p=1,000} OR=1,138 {95%CI:0,420–3,081}) and the sewer condition ({p=0,415} OR=0,551 {95%CI:0,187–1,624}). Environmental factors that associated with the risk of leptospirosis was the presence of rats ({p=0,001} OR=13,594 {95%CI:2,754–67,107}). The effort should be made in order to prevent the increasement of Leptospirosis cases by sanitation improvement and avoiding direct contact with rats as well as it litter. The Government should be pay more attention in the vector control programs, especially in leptospirosis prone areas so the prevention effort to be able run effectively and efficiently.


Author(s):  
S. G. Karthik ◽  
Edward B. Magrab

Abstract An intelligent graphical user interface that captures a product’s functional and assembly structure and the factory that will make it are described. The results are then used to evaluate a factory’s production rate for the product. The program requires the product to be either a functionally uncoupled or decoupled design. The interface then: (1) implements a visualization of the functionally decomposed product structure; (2) implements an abstraction of a factory; (3) automatically generates candidate primary manufacturing processes and materials that are compatible with each other based on a very small number of attributes; (4) enables the user to make Make/Buy decisions for the components comprising the product; (5) assists the user in the selection of secondary manufacturing processes that are compatible with the primary manufacturing processes and materials for parts made in-house, and specify the vendor and the supply lead time for outsourced parts; (6) enables the specification of alternate materials and manufacturing processes; (7) implements a visual representation of the assembly structure as specified by the user; and (8) partially automates the creation of the assembly structure, and assists in the selection of assembly methods that are compatible with the materials chosen. In addition, the program assists in the design for assembly by: (1) requiring the product development team to think about the assembly process early in the design stage; (2) providing a visualization of the relationship of all components comprising the product to its other components; (3) requiring the specification of the order in which they are to be assembled; and (4) requiring the selection of assembly processes that are compatible with each other and the materials chosen. It also requires the specification of the capabilities of the factory that is going to make one or more of the components of the product, and requires that Make/Buy decisions for the parts comprising the product be made.


Author(s):  
Kevin O’Neill

Teachers and researchers have been designing telementoring programs for more than fifteen years, yet there are many possible program designs that have not yet been attempted, and enormous potential yet to fulfill. An attempt is made to map out the “design space” of K-12 telementoring by discussing the major decisions made in designing a telementoring program, and the relationship of these decisions to one another. Where possible, research findings and examples of specific programs are cited in this discussion. By providing a look “under the hood” of telementoring programs, the chapter aims to help teachers become more equal partners in the effort to refine existing programs and develop new ones. Encouragement is offered to researchers to more fully articulate the rationale behind their designs in their writing, and to carry out more research on the efficacy of particular design choices, so that the field can develop cumulative literature on telementoring design.


Author(s):  
Keith Dowding

The chapter opens with some distinctions made in the study of power and semi-formally defines ‘outcome’ and ‘social’ or ‘power to’ and ‘power over’ showing the latter is a subset of the former. It argues both are legitimate ways of examining power. It argues that whilst ‘social power’ is often our concern, especially when discussing issues of freedom, domination and inequality we need to start by considering outcome power. Understanding why people can fail in their aims even when others are not acting against them – failure in their outcome power – is necessary for to understand the scope of social power. The chapter then examines the relationship between outcome power and freedom and discussesMorriss’s distinction between ability and ableness. Power is a dispositional concept and the ability that people have need to be distinguished from their exercise of their powers. It argues that if we only look at abilities we could eliminate the term power from our language since all we would need to is to look at their capacities or resources, but we also need to examine the way that agents change others incentives to act. The chapter introduces the formal aspects of the power index approach and through that discussion distinguishes power and luck. It then introduces bargaining power, formally distinguishes threats and offers and explains Harsanyi’s bargaining model of power and the extra element of reputation. It then discusses the relationship of luck and group power introducing the notion of systematic luck. It then concludes by discussing how we can study power in society.


1986 ◽  
Vol 10 (4) ◽  
pp. 339-352 ◽  
Author(s):  
Joan M. Singer ◽  
Jayne E. Stake

The relationship of math participation and success to self-esteem and career goals is examined in a sample of 64 women and 52 men college students at the end of their sophomore year. No gender differences were found in math anxiety or perceptions of the usefulness of mathematics, but women were less likely to select a math-related career goal. Among the men students, math participation and self-assessments of math ability were positively related to more general self-estimates of competence; among women, these variables were not related significantly. Women's choices for math-related careers were more closely associated with scholastic ability and math background than were men's career choices. These results are discussed in the context of societal pressures and supports for men and women in regard to math participation.


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