scholarly journals Depression as a Risk Factor for Physical Illness and Multimorbidity in a Cohort with No Prior Comorbidity: La Dépression Comme Facteur de Risque de Maladie Physique et de Multimorbidité Dans Une Cohorte Sans Comorbidité Antérieure

2020 ◽  
pp. 070674372097483
Author(s):  
Allanah Li ◽  
Laura C. Rosella ◽  
Paul Kurdyak ◽  
Walter P. Wodchis
Keyword(s):  
Short Form ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Physical Illness ◽  
Administrative Databases ◽  
Annual Household Income ◽  
Increased Risk ◽  
Nationally Representative ◽  
Regular Doctor

Objective: This study examines whether depression is associated with the development of physical illness and multimorbidity, after controlling for socioeconomic, behavioral, and other potential confounders. Methods: This is a retrospective cohort study in which adult respondents to three nationally representative population health surveys were linked to health administrative databases in Ontario, Canada, and followed for 10 years from survey index. Respondents with any of the study outcome conditions at baseline were excluded to create a final cohort of 29,838 participants. The main exposure of interest was depression, measured using the Composite International Diagnostic Interview–Short Form for Major Depression. We controlled for age, body mass index, marital status, immigrant status, annual household income, smoking, alcohol consumption, physical activity, health status, and having a regular doctor. The outcome measure was the development of physical illness over 10 years of follow-up, defined as 1 of 15 common chronic conditions using administrative data. Results: Among the 29,838 participants (15,259 [51%] female), 8% of females and 4% of males had depression at baseline. In this cohort with no comorbidities at baseline, even in the fully adjusted model, depression increased the risk of developing a first physical illness for females (hazard ratio [HR] 1.16; 95% CI, 1.07 to 1.26) and males (HR 1.20; 95% CI, 1.07 to 1.36) and increased the risk of developing a second physical illness for females (HR 1.16; 95% CI, 1.02 to 1.33) over 10 years of follow-up. Conclusions: For individuals with no prior comorbidities, depression is associated with a greater risk of developing subsequent physical illness and multimorbidity over time. Thus, depression identifies a population of people who may benefit from early identification, additional screening, and intervention. Further study needs to be done to determine whether interventions to manage and support people with depression can prevent or delay the increased risk of multimorbidity.

scholarly journals Myocardial infarction and generalised anxiety disorder: 10-year follow-up

2012 ◽  
Vol 200 (4) ◽  
pp. 324-329 ◽  
Author(s):  
Annelieke M. Roest ◽  
Marij Zuidersma ◽  
Peter de Jonge
Keyword(s):  
Myocardial Infarction ◽  
Anxiety Disorder ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Adverse Outcomes ◽  
Generalised Anxiety Disorder ◽  
Cardiovascular Prognosis ◽  
Increased Risk ◽  
And Gender

BackgroundFew studies have addressed the relationship between generalised anxiety disorder and cardiovascular prognosis using a diagnostic interview.AimsTo assess the association between generalised anxiety disorder and adverse outcomes in patients with myocardial infarction.MethodPatients with acute myocardial infarction (n = 438) were recruited between 1997 and 2000 and were followed up until 2007. Current generalised anxiety disorder and post-myocardial infarction depression were assessed with the Composite International Diagnostic Interview. The end-point consisted of all-cause mortality and cardiovascular-related readmissions.ResultsDuring the follow-up period, 198 patients had an adverse event. Generalised anxiety disorder was associated with an increased rate of adverse events after adjustment for age and gender (hazard ratio: 1.94; 95% confidence interval: 1.14–3.30; P = 0.01). Additional adjustment for measures of cardiac disease severity and depression did not change the results.ConclusionsGeneralised anxiety disorder was associated with an almost twofold increased risk of adverse outcomes independent demographic and clinical variables and depression.

scholarly journals Food Insecurity and Geriatric Hospitalization

2019 ◽  
Vol 16 (13) ◽  
pp. 2294
Author(s):  
Rachel S. Bergmans ◽  
Briana Mezuk ◽  
Kara Zivin
Keyword(s):  
Older Adults ◽  
Best Practices ◽  
Food Insecurity ◽  
Short Form ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Increased Risk ◽  
Bidirectional Relationship ◽  
Longitudinal Associations ◽  
Retirement Study

Food insecurity (FI) has been associated with hospitalization, although the pathways underlying this relationship are poorly understood, in part due to the potential for a bidirectional relationship. This study aimed to determine associations of FI with concurrent and future hospitalization among older adults; mediation by depression and; whether hospitalization increased risk of FI. Participants came from the 2012 and 2014 waves of the Health and Retirement Study (HRS; n = 13,664). HRS is a prospective cohort representative of U.S. adults over the age of 50. Primary analyses included those who were not hospitalized in 2012 (n = 11,776). Not having enough money to buy necessary food or eating less than desired defined food insecurity. The Composite International Diagnostic Interview Short Form provided depression symptomology. Logistic and linear regression examined concurrent and longitudinal associations of FI in 2012 and 2014 with hospitalization in 2014. Path analysis tested mediation of FI with hospitalization frequency by depression symptomology. Finally, logistic regression examined whether hospitalization in 2012 was longitudinally associated with FI in 2014. FI was not associated with future hospitalization (odds ratio (OR) = 1.1; 95% confidence interval (CI) = 0.9–1.4), however; FI was associated with concurrent hospitalization status (OR = 1.4; 95% CI = 1.1–1.8). Depression symptomology explained 17.4% (95% CI = 2.8–32.0%) the association of FI with concurrent hospitalization frequency. Additionally, hospitalization was associated with becoming food insecure (OR = 1.5; 95% CI = 1.2–2.0). Findings may inform best practices for hospital discharge among older adults.

scholarly journals The Depression Scale as a screening instrument for a subsequent depressive episode in primary healthcare patients

2007 ◽  
Vol 191 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Outi Poutanen ◽  
Anna-Maija Koivisto ◽  
Matti Joukamaa ◽  
Aino Mattila ◽  
Raimo K. R. Salokangas
Keyword(s):  
Primary Care ◽  
Primary Healthcare ◽  
Depressive Episode ◽  
Short Form ◽  
Depression Scale ◽  
Composite International Diagnostic Interview ◽  
Screening Instrument ◽  
Diagnostic Interview ◽  
Scale Scores

BackgroundThere are numerous instruments for screening for depression. A feasible screen is good at both recognising and predicting depression.AimsTo study the ability of the Depression Scale and its items to recognise and predict a depressive episode.MethodA sample of patients attending primary care was examined in 1991–1992 and again 7 years later. The accuracy of the Depression Scale at baseline and at follow-up was tested against the Short Form of the Composite International Diagnostic Interview (CIDI-SF) diagnosis of depression at follow-up. The sensitivity and specificity of the Depression Scale and its items were assessed.ResultsBoth baseline and follow-up Depression Scale scores were consistent with the CIDI–SF diagnoses. It was possible to find single items efficient at both recognising and predicting depression.ConclusionsThe Depression Scale is a useful screening instrument for depression, with both diagnostic and predictive validity.

scholarly journals Family functioning but not social capital is associated with better mental health in adolescents affected by violence and displacement by armed conflict in Colombia

2021 ◽  
pp. 002076402110454
Author(s):  
William Tamayo-Aguledo ◽  
Alida Acosta-Ortiz ◽  
Aseel Hamid ◽  
Carolina Gómez-García ◽  
María Camila García-Durán ◽  
...  
Keyword(s):  
Mental Health ◽  
Social Capital ◽  
Family Functioning ◽  
Armed Conflict ◽  
Composite International Diagnostic Interview ◽  
Poor Mental Health ◽  
Diagnostic Interview ◽  
Cross Sectional ◽  
Nationally Representative ◽  
Cognitive Social Capital

Background: The effect of the Colombian armed conflict on the mental health of adolescents is still poorly understood. Aims: Given social interventions are most likely to inform policy, we tested whether two potential intervention targets, family functioning and social capital, were associated with mental health in Colombian adolescents, and whether this was moderated by experience of violence and displacement. Methods: We examined the cross-sectional association between family functioning, cognitive social capital, structural social capital and 12-month prevalence of Composite International Diagnostic Interview (CIDI) diagnosed psychiatric disorder, using data on 12 to 17-year-old adolescents ( N = 1,754) from the 2015 National Mental Health Survey of Colombia, a nationally representative epidemiological study. We tested whether associations survived cumulative adjustment for demographic confounders, experience of non-specific violence and harm and displacement by armed conflict. Results: Neither structural nor cognitive social capital were associated with better mental health. Better family functioning was associated with reduced risk of poor mental health in an unadjusted analysis (OR 0.90 [0.85–0.96]), and after cumulative adjustments for demographic confounders (OR 0.91 [0.86–0.97]), non-specific violence and harm (OR 0.91 [0.86–0.97]) and social capital variables (OR 0.91 [0.85–0.97]). In the final model, each additional point on the family APGAR scale was associated with a 9% reduced odds of any CIDI diagnosed disorder in the last 12 months. Conclusions: Better family functioning was associated with better mental health outcomes for all adolescents. This effect remained present in those affected by the armed conflict even after accounting for potential confounders.

scholarly journals Shades of Blue and Gray: A Comparison of the Center for Epidemiologic Studies Depression Scale and the Composite International Diagnostic Interview for Assessment of Depression Syndrome in Later Life

2019 ◽  
Vol 60 (4) ◽  
pp. e242-e253 ◽  
Author(s):  
Linh Dang ◽  
Liming Dong ◽  
Briana Mezuk
Keyword(s):  
Short Form ◽  
Depression Scale ◽  
Composite International Diagnostic Interview ◽  
Later Life ◽  
Epidemiologic Studies ◽  
Diagnostic Interview ◽  
Psychiatric Research ◽  
And Gender ◽  
Ethnicity And Gender ◽  
Design And Methods

Abstract Background and Objectives Psychiatric research lacks the equivalent of a thermometer, that is, a tool that accurately measures mental disorder regardless of context. Instead, the psychometric properties of scales that purport to assess psychopathology must be continuously evaluated. To that end, this study evaluated the diagnostic agreement between the eight-item Center for Epidemiologic Studies Depression Scale (CESD-8) and the Composite International Diagnostic Interview—short form (CIDI-SF) in the Health and Retirement Study (HRS). Research Design and Methods Data come from 17,613 respondents aged >50 from the 2014 wave of the HRS. Kappa coefficients were used to assess the agreement between the 2 instruments on depression classification across a range of thresholds for identifying case status, including variation across subgroups defined by age, race/ethnicity, and gender. Results The point prevalence of depression syndrome estimated by the CESD was higher than that estimated by the CIDI-SF (CESD: 9.9%–19.5% depending on the cutoff applied to the CESD vs CIDI-SF: 7.7%). Assuming CIDI-SF as the gold standard, the CESD yielded a sensitivity of 56.2%–70.2% and specificity of 84.7%–94.0% across the range of cutoffs. The agreement on depression classification was weak (κ = 0.32–0.44). Discussion and Implications Depression cases identified by the CESD have poor agreement with those identified by the CIDI-SF. Conceptually, psychological distress as measured by the CESD is not interchangeable with depression syndrome as measured by the CIDI-SF. Population estimates of depression among older adults based on the CESD should be interpreted with caution.

scholarly journals Physical Functioning Decline and Mortality in Older Adults With Multimorbidity: Joint Modeling of Longitudinal and Survival Data

2018 ◽  
Vol 74 (2) ◽  
pp. 226-232 ◽  
Author(s):  
Melissa Y Wei ◽  
Mohammed U Kabeto ◽  
Andrzej T Galecki ◽  
Kenneth M Langa
Keyword(s):  
Older Adults ◽  
Mortality Risk ◽  
Physical Functioning ◽  
Survival Data ◽  
Short Form ◽  
Joint Modeling ◽  
Full Spectrum ◽  
Increased Risk ◽  
The Impact

Abstract Background Multimorbidity is common among older adults and strongly associated with physical functioning decline and increased mortality. However, the full spectrum of direct and indirect effects of multimorbidity on physical functioning and survival has not been quantified. We aimed to determine the longitudinal relationship of multimorbidity on physical functioning and quantify the impact of multimorbidity and multimorbidity-attributed changes in physical functioning on mortality risk. Methods The Health and Retirement Study (HRS) is a nationally representative population-based prospective cohort of adults aged 51 or older. In 2000, participants were interviewed about physician-diagnosed chronic conditions, from which their multimorbidity-weighted index (MWI) was computed. Between 2000 and 2011, participants reported their current physical functioning using a modified Short Form-36. With MWI as a time-varying exposure, we jointly modeled its associations with physical functioning and survival. Results The final sample included 74,037 observations from 18,174 participants. At baseline, participants had a weighted mean MWI of 4.6 ± 4.2 (range 0–36.8). During follow-up, physical functioning declined: −1.72 (95% confidence interval [CI] −1.77, −1.67, p < .001) HRS physical functioning units per point MWI in adjusted models. Over follow-up, 6,362 (34%) participants died. Mortality risk increased 8% (hazard ratio 1.08, 95% CI 1.07–1.08, p < .001) per point MWI in adjusted models. Across all population subgroups, MWI was associated with greater physical functioning decline and mortality risk. Conclusions Multimorbidity and its associated decline in physical functioning were significantly associated with increased mortality. These associations can be predicted with an easily interpreted and applied multimorbidity index that can better identify and target adults at increased risk for disability and death.

scholarly journals Childhood Adversities and Traumata in Lebanon: A National Study

2014 ◽  
Vol 10 (1) ◽  
pp. 116-125 ◽  
Author(s):  
Lynn Itani ◽  
Youmna C Haddad ◽  
John Fayyad ◽  
Aimee Karam ◽  
Elie Karam
Keyword(s):  
Traumatic Event ◽  
Traumatic Events ◽  
Composite International Diagnostic Interview ◽  
Female Gender ◽  
National Sample ◽  
Diagnostic Interview ◽  
National Study ◽  
Childhood Adversities ◽  
Nationally Representative ◽  
Personal Trauma

Background: The goal of this paper is to map the total occurrence and evaluate the risk of co-occurrence of childhood adversities (CA) and a wide variety of childhood traumatic events (including war) in a national sample. Method: The nationally representative sample included 2,857 respondents and the instrument used was the Composite International Diagnostic Interview which screened for all CAs and traumatic events. Results: 27.9% experienced CAs; the most common were parental death and parental mental/substance use disorder. 70.6% experienced a war-related traumatic event during their lifetime, and around half of them (38.1%) experienced it below the age of 18 years. 51.3% of the subjects experienced a traumatic event not related to war during their lifetime, and 19.2% experienced it before the age of 18 years. Sexual abuse, being a refugee during war, and experiencing a natural disaster were associated with female gender. Having any CA was associated with active war exposure (OR: 4.2, CI: 2.0-8.6); war-related direct personal trauma (OR: 3.9, CI: 1.5-10.0); war-related trauma to others (OR: 2.4, CI: 1.3-4.4); non-war direct personal trauma (OR: 3.8, CI: 2.0-7.4); and any non-war childhood traumatic event (OR: 1.9, CI: 1.1-3.1). Conclusion:Childhood is awash with adversities and traumatic events that co-occur and should be measured simultaneously; otherwise, the effects of a subset of traumata or adversities could be wrongly thought to be the contributor to negative outcomes under study.

scholarly journals The Moderating Effects of Coping Strategies on Major Depression in the General Population

2002 ◽  
Vol 47 (2) ◽  
pp. 167-173 ◽  
Author(s):  
JianLi Wang ◽  
Scott B Pat ten
Keyword(s):  
Major Depression ◽  
General Population ◽  
Coping Strategies ◽  
Life Stress ◽  
Depressive Disorders ◽  
Short Form ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
World Health ◽  
Moderating Effects

Objectives: To evaluate the moderating effects of various coping strategies on the as sociation between stressors and the prevalence of major depression in the general population. Methods: Subjects from the Alberta buy- incomponent of the 1994 –1995 National Population Health Survey (NPHS) were included in the analysis ( n = 1039). Each subject was asked 8 questions about coping strategies that dealt with unexpected stress from family problems and personal crises. Major depression was measured using the World Health Organization's (WHO) Composite International Diagnostic Interview-Short Form (CIDI- SF) for major depression. The im pacts of coping strategies in relation to psychological stres sors on the prevalence of major depression were de ter mined by examining interactions between coping and life stress on major depression using logistic regression modelling. Results: No robust impact of coping strategies in relation to various categories of stress evaluated in the NPHS was observed. There was evidence that the use of “pray and seek religious help” and “talks to others about the situations” as coping strategies by women moderated the risk of major depression in the presence of financial stress and relation ship stress (with a partner). Using emotional expression as a coping strategy by women might de crease the risk of major depression in the presence of 1 or more re cent life events, personal stress, relationship stress (with a partner), and environmental stress. Conclusion: Different coping strategies may have a differential impact on the prevalence of major depression in specific circumstances. These findings may be important both to prevent and to treat depressive disorders.

scholarly journals Comorbid Depression among Untreated Illicit Opiate Users: Results from a Multisite Canadian Study

2005 ◽  
Vol 50 (9) ◽  
pp. 512-518 ◽  
Author(s):  
T Cameron Wild ◽  
Nady el-Guebaly ◽  
Benedickt Fischer ◽  
Suzanne Brissette ◽  
Serge Brochu ◽  
...  
Keyword(s):  
Major Depression ◽  
Drug Use ◽  
Service Use ◽  
Short Form ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Quebec City ◽  
Comorbid Depression ◽  
Chi Square ◽  
Targeted Interventions

Objectives: This study aimed to describe patterns of major depression (MDD) in a cohort of untreated illicit opiate users recruited from 5 Canadian urban centres, identify sociodemographic characteristics of opiate users that predict MDD, and determine whether opiate users suffering from depression exhibit different drug use patterns than do participants without depression. Method: Baseline data were collected from 679 untreated opiate users in Vancouver, Edmonton, Toronto, Montreal, and Quebec City. Using the Composite International Diagnostic Interview Short Form for Major Depression, we assessed sociodemographics, drug use, health status, health service use, and depression. We examined depression rates across study sites; logistic regression analyses predicted MDD from demographic information and city. Chi-square analyses were used to compare injection drug use and cocaine or crack use among participants with and without depression. Results: Almost one-half (49.3%) of the sample met the cut-off score for MDD. Being female, white, and living outside Vancouver independently predicted MDD. Opiate users suffering from depression were more likely than users without depression to share injection equipment and paraphernalia and were also more likely to use cocaine ( Ps < 0.05). Conclusions: Comorbid depression is common among untreated opiate users across Canada; targeted interventions are needed for this population.

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