scholarly journals Are Changes in Self-Rated Health Associated With Memory Decline in Older Adults?

2016 ◽  
Vol 29 (8) ◽  
pp. 1410-1423 ◽  
Author(s):  
Rebecca Bendayan ◽  
Andrea M. Piccinin ◽  
Scott M. Hofer ◽  
Graciela Muniz
Keyword(s):  
Older Adults ◽  
Delayed Recall ◽  
Memory Decline ◽  
Screening Programs ◽  
Self Rated Health ◽  
Good Pattern ◽  
Approach Method ◽  
Rate Of Decline ◽  
Fair Poor ◽  
With Memory

Objective: The association between patterns of change in self-rated health (SRH) and memory trajectories in older adults was examined using a systematic approach. Method: Data from the Health and Retirement Study ( n = 6,016) and the English Longitudinal Study of Ageing ( n = 734) were analyzed. Individuals were grouped into five categories according to their pattern of change in SRH over 8 years: stable excellent/very good/good, stable fair/poor, improvement, decline, and fluctuating pattern without a trend. Memory was measured using immediate and delayed recall tests. Kruskal–Wallis, chi-squares tests, and linear mixed models were used to examine the association. Results: Different rates of decline in memory can be identified in the different patterns of change in SRH. Those who had a stable excellent/very good/good pattern had the slowest rate of decline. Discussion: Our findings suggest that SRH status and patterns of change could be used as a marker of cognitive decline in prevention screening programs.

scholarly journals Memory Decline and Depression Onset in U.S. and European Older Adults

2018 ◽  
Vol 32 (3-4) ◽  
pp. 189-198
Author(s):  
Rebecca Bendayan ◽  
Amanda Kelly ◽  
Scott M. Hofer ◽  
Andrea M. Piccinin ◽  
Graciela Muniz-Terrera
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Empirical Evidence ◽  
Mixed Models ◽  
Delayed Recall ◽  
Memory Decline ◽  
Lower Baseline ◽  
Health Aging ◽  
Persistent Depression ◽  
Retirement Study

Objectives: We explore the association between different patterns of change in depressive symptoms and memory trajectories in US and European Mediterranean (Spain, France, Italy, and Israel) and non-Mediterranean (Sweden, Denmark, Netherlands, Germany, Belgium, Switzerland, and Austria) older adults. Methods: Samples consisted of 3,466 participants from the Health Retirement Study (HRS) and 3,940 participants from the Survey of Health, Aging and Retirement (SHARE). Individuals were grouped as follows: non-case depression (NO DEP), persistent depression (DEP), depression onset (ONSET), depression recovery (RECOV), and fluctuating (FLUCT). Memory was measured using immediate and delayed recall tests. Linear mixed models were used. Results: DEP and RECOV had significantly lower baseline memory scores compared to NO DEP, at intercept level. At slope level, ONSET had a significantly faster decline in both tasks compared to NO DEP. Discussion: Cross-cohort robust and consistent new empirical evidence on the association between depression onset and faster decline in memory scores is provided.

scholarly journals Musical instrument engagement across the life course and episodic memory in late life: An analysis of 60 years of longitudinal data from the Wisconsin Longitudinal Study

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253053
Author(s):  
Jamie L. Romeiser ◽  
Dylan M. Smith ◽  
Sean A. P. Clouston
Keyword(s):  
High School ◽  
Episodic Memory ◽  
Cognitive Reserve ◽  
High School Graduates ◽  
Musical Instrument ◽  
Delayed Recall ◽  
Memory Decline ◽  
Musical Engagement ◽  
Rate Of Decline ◽  
Over Time

Background As the global burden of dementia increases, the absence of treatment underscores the need for identification of factors that may improve cognitive reserve–the ability to stave off cognitive decline in old age. The beneficial association between musical instrument engagement and episodic memory has been identified in children, young adults, and older adults. Yet, previous studies in musical instrument engagement have rarely examined the potential for adolescence and adulthood exposures to independently improve cognition, nor have they been linked with the rate of memory decline over time in older adults. We investigated whether adolescent musical instrument engagement and continued musical instrument engagement over the adult life course were separately associated with higher episodic memory, as well as rate of decline in a large longitudinal cohort. Methods Data were from a prospective cohort of high school graduates from 1957. High school music engagement (HSME) was ascertained through graduate yearbooks and assessed as membership in musical performance groups. A questionnaire was used to assess musical engagement through adulthood (MEA) at ages 35, 55, and 65. The episodic memory score was composed of immediate and delayed recall task scores, and was assessed when participants were aged approximately 65 and 72 years old among 5,718 individuals. Linear mixed models were used to assess the association between music, and memory performance and decline over time. Results Of high school graduates who participated in the study, 38.1% played music in high school, and 21.1% played music in adulthood. While musical engagement was more common in those who played in childhood, 40% of those who played continuously as an adult did not play in high school. High HSME (B = 0.348, p = 0.049) and continuous MEA (B = 0.424, p = 0.012) were associated with higher memory scores at age 65 after covariate adjustment. When examining memory decline, the benefits of high HSME decreased over time (B = -0.435, p = 0.048), while the rate of decline did not differ between MEA groups. Exploratory models revealed differential benefits for HSME and immediate recall, and MEA and delayed recall. Conclusion This study provides further evidence that musical engagement in childhood or adulthood is associated with non-musical cognitive reserve. These two exposures may act differentially in different domains of episodic memory. Further work is needed to determine the relationship between musicianship and the rate of cognitive decline.

scholarly journals Religiosity and self-rated health among older adults in Colombia

2019 ◽  
pp. 67-76
Author(s):  
Carlos A Reyes Ortiz ◽  
Claudia Payan ◽  
Geraldine Altamar ◽  
Jose F Gomez Montes ◽  
Harold G Koenig
Keyword(s):  
Older Adults ◽  
Rural Areas ◽  
Community Dwelling ◽  
Cross Sectional Survey ◽  
Significant Interaction Effect ◽  
Cross Sectional ◽  
Self Rated Health ◽  
Urban And Rural Areas ◽  
Fair Poor ◽  
The Relationship

Objective: To identify the relationship between religiosity and self-rated health among older adults in Colombia. Methods: Data are drawn from the SABE (Salud, Bienestar y Envejecimiento) Colombia Study, a cross-sectional survey conducted in 2015 involving 18,871 community-dwelling adults aged 60 years and older living in urban and rural areas of Colombia. Religiosity was assessed by self-rated religiosity (how religious are you: not at all, somewhat or very). Self-rated health during previous 30 days was assessed as very good, good, fair, poor or very poor, analyzed as an ordinal variable(1-5) using weighted logistic regression, adjusting for confounders. Results: Those who were more religious were older, female, had lower socioeconomic status, and were more likely to be married. Multivariate analyses demonstrated that older adults who were more religious had better self-rated health (OR 0.92 95% CI 0.86- 0.99, p= 0.038); however, there was a significant interaction effect between gender and religiosity on self-rated health (p= 0.002), such that the relationship between religiosity and health was stronger in men (OR 0.86, 95% CI: 0.79-0.94, p= 0.001) but not significant in women. Conclusion: Older adults in Colombia who consider themselves more religious, especially men, are less likely to perceive their physical health as poor compared to those who are less religious.

scholarly journals Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults Undergoing Coronary Revascularization

JAMA ◽  
2021 ◽  
Vol 325 (19) ◽  
pp. 1955
Author(s):  
Elizabeth L. Whitlock ◽  
L. Grisell Diaz-Ramirez ◽  
Alexander K. Smith ◽  
W. John Boscardin ◽  
Kenneth E. Covinsky ◽  
...  
Keyword(s):  
Older Adults ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Coronary Revascularization ◽  
Artery Bypass ◽  
Coronary Intervention ◽  
Bypass Grafting ◽  
Memory Decline ◽  
Percutaneous Coronary ◽  
With Memory

scholarly journals Cardiovascular risk factors and memory decline in middle-aged and older adults: the English Longitudinal Study of Ageing

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Beatriz Olaya ◽  
Maria Victoria Moneta ◽  
Martin Bobak ◽  
Josep Maria Haro ◽  
Panayotes Demakakos
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Longitudinal Study ◽  
Cognitive Decline ◽  
Cardiovascular Risk Factors ◽  
Middle Aged ◽  
Memory Decline ◽  
With Memory ◽  
English Longitudinal Study

Abstract Background We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers. Methods We analysed data from 4372 participants aged 50–64 and 3005 persons aged 65–79 years old from the English Longitudinal Study of Ageing who were repeatedly evaluated every 2 years and had six interviews of a 10-year follow-up. We measured the following baseline risk factors: diabetes, hypertension, smoking, physical inactivity and obesity to derive a cardiovascular risk factor score (CVRFs). Adjusted linear mixed effect regression models were estimated to determine the association between number of CVFRs and six repeated measurements of verbal memory scores, separately for middle-aged and older adults. Results CVRFs was not significantly associated with memory at baseline. CVFRs was significantly associated with memory decline in middle-aged (50-64y), but not in older (65-79y) participants. This association followed a dose-response pattern with increasing number of CVFRs being associated with greater cognitive decline. Comparisons between none versus some CVRFs yielded significant differences (p < 0.05). Conclusions Our findings confirm that the effect of cumulative CVRFs on subsequent cognitive deterioration is age-dependent. CVRFs are associated with cognitive decline in people aged 50–64 years, but not in those aged ≥65 years. Although modest, the memory decline associated with accumulation of cardiovascular risk factors in midlife may increase the risk of late-life dementia.

scholarly journals Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers

Neurology ◽  
2017 ◽  
Vol 89 (17) ◽  
pp. 1782-1788 ◽  
Author(s):  
Kaitlin B. Casaletto ◽  
Fanny M. Elahi ◽  
Brianne M. Bettcher ◽  
John Neuhaus ◽  
Barbara B. Bendlin ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Aging ◽  
Brain Aging ◽  
Memory Performance ◽  
Verbal Learning ◽  
Delayed Recall ◽  
Age Related ◽  
T Tau ◽  
The Relationship ◽  
With Memory

Objective:To determine the association between synaptic functioning as measured via neurogranin in CSF and cognition relative to established Alzheimer disease (AD) biomarkers in neurologically healthy older adults.Methods:We analyzed CSF concentrations of neurogranin, β-amyloid (Aβ42), phosphorylated tau (p-tau), and total tau (t-tau) among 132 neurologically normal older adults (mean 64.5, range 55–85), along with bilateral hippocampal volumes and a measure of episodic memory (Auditory Verbal Learning Test, delayed recall). Univariable analyses examined the relationship between neurogranin and the other AD-related biomarkers. Multivariable regression models examined the relationship between neurogranin and delayed recall, adjusting for age and sex, and interaction terms (neurogranin × AD biomarkers).Results:Higher neurogranin concentrations were associated with older age (ρ = 0.20, p = 0.02), lower levels of p-tau and t-tau, and smaller hippocampal volumes (p < 0.03), but not with CSF Aβ42 (p = 0.18). In addition, CSF neurogranin demonstrated a significant relationship with memory performance independent of the AD-related biomarkers; individuals with the lowest CSF neurogranin concentrations performed better on delayed recall than those with medium or high CSF neurogranin concentrations (p < 0.01). Notably, CSF p-tau, t-tau, and Aβ42 and hippocampal volumes were not significantly associated with delayed recall scores (p > 0.40), and did not interact with neurogranin to predict memory (p > 0.10).Conclusions:Synaptic dysfunction (assessed via neurogranin) may be an early pathologic process in age-related neurodegeneration, and a sensitive marker of age-related cognitive abilities, potentially preceding or even acting independently from AD pathogenesis. Synaptic functioning may be a useful early marker of cognitive aging and possibly a target for future brain aging interventions.

scholarly journals Spouse-Appraised Memory Functioning Predicts Memory Decline Better Than Subjective Memory Complaints in Community Dwelling Older Adults at Genetic Risk for Alzheimer's Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Youssef Bellaali ◽  
John L. Woodard ◽  
Bernard Hanseeuw ◽  
Adrian Ivanoiu
Keyword(s):  
Older Adults ◽  
Community Dwelling ◽  
Carrier Status ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Memory Decline ◽  
Apoe Ε4 ◽  
Memory Functioning ◽  
Community Dwelling Older Adults ◽  
With Memory

Objective: Alzheimer's disease (AD) begins with subtle memory decline, years before dementia onset. The presence of subjective memory complaints (SMC) has been proposed as a marker of preclinical AD. However, recent evidence has demonstrated early and progressive loss of awareness of memory difficulties in non-demented older adults harboring AD pathology. We investigated the respective contributions of SMC and spouse-appraised memory functioning (SAM) to predict memory decline in a large cohort of community dwelling older adults.Methods: The Wisconsin Longitudinal Study collected cognitive data from a community-based cohort of 3,583 participants in both 2005 and 2011. The participant and the participant's spouse were each asked to rate the participant's memory functioning using a Likert scale. We predicted change in objective episodic memory with models including baseline SMC, baseline SAM, or both SMC and SAM. We also evaluated an awareness index (SMC minus SAM). We then tested the interaction between Apolipoprotein E (APOE ε4) carrier status and SMC/SAM to evaluate whether the effects were driven by individuals at-risk for AD pathology.Results: In separate models, SMC (−0.081 ± 0.036, p = 0.025) and SAM (−0.084 ± 0.278, p = 0.003) were both associated with memory decline over ~6 years. However, the AI was not significantly associated with memory decline (0.031 ± 0.024, p = 0.19). When both predictors were included in the same model, SAM (−0.074 ± 0.03, p = 0.0092) was associated with memory decline, while SMC was not significant (−0.061 ± 0.04, p = 0.99). The association between SAM and memory decline was stronger in the APOE ε4 carriers than in the non-carriers (APOE-by-SAM interaction: F = 6.07; p = 0.002), and follow up analyses revealed that SAM was particularly predictive of decline only for APOE ε4 carriers. The association between SMC and memory decline was independent of APOE ε4 carrier status (APOE-by-SMC interaction: F = 2.29; p = 0.13).Conclusions: Spouse-appraised memory functioning was more predictive of memory decline than SMC or an awareness index, particularly in APOE ε4 carriers, who are at increased risk for AD pathology.

scholarly journals LONGITUDINAL ASSOCIATIONS BETWEEN PERCEIVED STRESS AND MEMORY COMPLAINTS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S220-S221
Author(s):  
Tyler Bell ◽  
Tyler Bell ◽  
Jacqueline Mogle ◽  
Nikki Hill
Keyword(s):  
Older Adults ◽  
Perceived Stress ◽  
Multilevel Models ◽  
Memory Decline ◽  
Memory Complaints ◽  
Aging Study ◽  
One Year ◽  
Stress Influences ◽  
Cognitively Intact ◽  
With Memory

Abstract Memory complaints increase cognitive decline but show weak concurrent associations with objective memory. Instead, affect might underlie some memory complaints and their impact on future cognition. Perceived stress influences cognitive performance, but temporal associations with memory complaints is unknown. We therefore explored longitudinal relationships between perceived stress and memory complaints among cognitively normal older adults. From the Einstein Aging Study (n=507, Mage=77.88, 63.30% female; 73.21% White), multilevel models examined bi-directional concurrent and one-year-lagged associations between within-person changes in perceived stress and memory complaints (frequency of forgetting, perceived one-year memory decline, perceived ten-year memory decline). Perceived stress positively covaried with memory complaints. Looking at lagged effects, only frequency of forgetting predicted next-year perceived stress. Higher frequency of forgetting thus increases perceived stress while perceived decline associates with current perceived stress. Reframing perceptions of forgetfulness might reduce stress in cognitively intact older adults, which in turn may benefit cognition long term.

scholarly journals Links between autobiographical memory richness and temporal discounting in older adults

2019 ◽  
Author(s):  
Karolina M. Lempert ◽  
Kameron A. MacNear ◽  
David A. Wolk ◽  
Joseph W. Kable
Keyword(s):  
Older Adults ◽  
Autobiographical Memory ◽  
Cortical Thickness ◽  
Temporal Discounting ◽  
Autobiographical Memories ◽  
Memory Decline ◽  
Fine Grained ◽  
Making Choices ◽  
Future Outcomes ◽  
With Memory

AbstractWhen making choices between smaller, sooner rewards and larger, later ones, people tend to discount or devalue future outcomes. This propensity can be maladaptive, especially as individuals age and their decisions about health, investments, and relationships become increasingly consequential. Individual differences in temporal discounting in older adults have been associated with episodic memory abilities, as well as with cortical thickness in the entorhinal cortex. The mechanism by which better memory might lead to more future-oriented choice remains unclear, however. Here we used a fine-grained measure of autobiographical memory richness (Autobiographical Interview scoring protocol) to examine which categories of episodic details are associated with temporal discounting in cognitively normal older adults. We also examined whether recalling autobiographical memories prior to choice can alter temporal discounting in this group. Time, place, and perceptual details, but not event or emotion/thought details, were associated with temporal discounting. Furthermore, time, place, and perceptual details and temporal discount rates were associated with entorhinal cortical thickness. Retrieving autobiographical memories prior to choice did not affect temporal discounting overall, but the extent to which the memories were rich in event and time details predicted whether they would reduce discounting after they were recalled. Thus, more future-oriented decision-makers may have more contextual (i.e., time, place, and perceptual) details in their recollections overall, and retrieving central event details at the time of choice may shift decisions toward being more patient. These findings will help with the development of interventions to nudge intertemporal choices, especially in older adults with memory decline.

Sign in / Sign up

Export Citation Format

Share Document