Epidemiology and clinics of mushroom poisoning in Northern Italy: A 21-year retrospective analysis

2017 ◽  
Vol 37 (7) ◽  
pp. 697-703 ◽  
Author(s):  
G Cervellin ◽  
I Comelli ◽  
G Rastelli ◽  
F Sanchis-Gomar ◽  
F Negri ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Early Identification ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Clinical Information ◽  
Northern Italy ◽  
Gastrointestinal Toxicity ◽  
Mushroom Poisoning ◽  
Limited Information ◽  
Life Threatening

Background: Limited information exists about epidemiology and management of mushroom poisoning. We analyzed and described epidemiology, clinical presentation, and clinical course of mushroom-poisoned patients admitted to emergency departments (EDs) of the Province of Parma, Italy. Methods: Data from the database of mycological service were matched with clinical information retrieved from hospitals’ database, from January 1, 1996 to December 31, 2016. Results: Mycologist consultation was obtained in 379/443 identified mushroom poisonings. A remarkable seasonality was found, with significant peak in autumn. Thanks to the collaboration, the implicated species could be identified in 397 cases (89.6%); 108 cases (24.4%) were due to edible mushrooms, Boletus edulis being the most represented (63 cases). Overall, 408 (92%) cases presented with gastrointestinal toxicity. Twenty cases of amatoxin poisoning were recorded (11 Amanita phalloides and 9 Lepiota brunneoincarnata). One liver transplantation was needed. We observed 13 cases of cholinergic toxicity and 2 cases of hallucinogenic toxicity. Finally, 46 cases were due to “mixed” toxicities, and a total of 69 needed hospitalization. Conclusions: Early identification and management of potentially life-threatening cases is challenging in the ED, so that a mycologist service on call is highly advisable, especially during periods characterized by the highest incidence of poisoning.

scholarly journals Complicated staphylococcal pericarditis in a child: a case report

2020 ◽  
Vol 7 (11) ◽  
pp. 2252
Author(s):  
Fehmida Sultana ◽  
Deepti Jujaray ◽  
Ravi P. V. Kiran
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Early Identification ◽  
Clinical Presentation ◽  
Paediatric Population ◽  
Acute Pericarditis ◽  
Life Threatening

Although primary pericarditis is unusually experienced and diagnosed in paediatric population, it has probable life threatening sequel. This case report presents a case of complicated community acquired staphylococcal pericarditis, which illustrates how evasive the diagnosis of pericardial effusion can be. Early identification of pericarditis and pericardial effusion is vital to enable emergent intervention to enhance prognosis and alleviate mortality. The purpose of this report is to probe into the etiology of acute pericarditis and also to review the clinical presentation, the management and complications connected with acute pericarditis. 

Pleomorphic xanthoastrocytoma presenting with life-threatening hemorrhage in a child

2009 ◽  
Vol 3 (2) ◽  
pp. 157-159 ◽  
Author(s):  
Joshua J. Wind ◽  
P. Benjamin Kerr ◽  
Jennifer A. Sweet ◽  
Vivek R. Deshmukh
Keyword(s):  
Intracerebral Hemorrhage ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Case Reports ◽  
Young Patients ◽  
Pleomorphic Xanthoastrocytoma ◽  
First Case ◽  
Life Threatening

Pleomorphic xanthoastrocytomas are glial-based tumors that arise most frequently in young patients and usually follow a more benign and indolent clinical course than their other glial-based tumor counterparts. These tumors most frequently present with seizures, and only 3 previous case reports exist of hemorrhagic tumor as the clinical presentation. The authors present the first case of life-threatening intracerebral hemorrhage from pleomorphic xanthoastrocytoma in a child.

scholarly journals Recurrent hepatobiliary sepsis in a patient with von Meyenburg complexes: a case report and review of the literature

2016 ◽  
Vol 26 (2) ◽  
pp. 133-136 ◽  
Author(s):  
Doreen Siew Ching Koay ◽  
Wei Qiang Leow ◽  
Thuan Tong Tan ◽  
Gabrielle Slapak
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Congenital Malformation ◽  
Medical Therapy ◽  
Clinical Presentation ◽  
Review Of The Literature ◽  
Unique Case ◽  
Von Meyenburg Complex ◽  
Life Threatening ◽  
Immunodeficiency States

The von Meyenburg complex (VMC) is a rare, congenital malformation of the ductal plate. It is typically asymptomatic and usually discovered incidentally. We report a unique case of recurrent life-threatening hepatobiliary sepsis caused by VMC and a review of the literature. A 62-year-old man presented with recurrent episodes of life-threatening hepatobiliary sepsis. Extensive investigations only showed that he has VMCs without any other source of sepsis or underlying immunodeficiency states. Despite prolonged courses of antibiotics which resolved each episode of sepsis, he suffers repeated recurrences of hepatobiliary sepsis. Liver transplantation is now being considered in view of his refractoriness to medical therapy. As VMC can present with severe hepatobiliary sepsis, it is therefore essential to recognise its presence. This case adds to the literature the atypical but life-threatening clinical presentation of VMC.

scholarly journals Sumag (sulphacetamide) induced allergic reaction, aggravating superficial thrombophlebitis

2020 ◽  
Vol 7 (10) ◽  
pp. 1579
Author(s):  
Dharmendra Jain ◽  
Abhishek Kaushley ◽  
Vaibhav Mishra
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Case Report ◽  
Allergic Reaction ◽  
Early Identification ◽  
Clinical Course ◽  
Superficial Thrombophlebitis ◽  
Management Of Complications ◽  
Life Threatening

Adverse drug reaction (ADR) is not only require early identification of the offending drugs but also requires proper care and management of complications. Also adverse drug reaction need to be differentiated from the problem unrelated to the drug so that needed medications are not unnecessarily stopped. Adverse drug reaction may be unpredictable and represent a life-threatening risk. ADR can also complicate the management of any infection. This case report provide the precise clinical course of a rare ADR.

Lemierre syndrome – a forgotten complication of acute tonsillitis

1995 ◽  
Vol 109 (7) ◽  
pp. 657-661 ◽  
Author(s):  
C. B. Koay ◽  
T. Heyworth ◽  
P. Burden
Keyword(s):  
Young Adults ◽  
Mortality Rate ◽  
Clinical Picture ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Disease Process ◽  
Acute Tonsillitis ◽  
Lemierre Syndrome ◽  
Threatening Condition ◽  
Life Threatening

AbstractLemierre syndrome, also known as postanginal sepsis, is an illness characterized by the development of a fusobacterial septicaemia with multiple metastatic foci following an attack of acute tonsillitis. It typically affects previously healthy adolescents and young adults who, following an attack of sore throat, become acutely ill with hyperpyrexia, rigors and multiple metastatic abscesses. The clinical picture tends to vary widely because of the possible involvement of a number of body systems and organs in the disease process. This serious complication of oropharyngeal sepsis had a mortality rate in excess of 90 percent in the pre-antibiotic era. Although now rarely seen and often forgotten, it remains a potentially life-threatening condition. We present four cases of post-tonsillitis fusobacterial septicaemia to illustrate the variability of the clinical presentation and stormy clinical course frequently associated with this rare syndrome.

Escherichia coli Sepsis and Prolonged Hypophosphatemia Following Exertional Heat Stroke

PEDIATRICS ◽  
1990 ◽  
Vol 86 (2) ◽  
pp. 307-309
Author(s):  
MARK A. KAY ◽  
EDWARD D. B. MCCABE
Keyword(s):  
Early Identification ◽  
Sports Medicine ◽  
Clinical Course ◽  
Heat Stroke ◽  
Altered Mental Status ◽  
Exertional Heat Stroke ◽  
Gram Negative ◽  
American Academy Of Pediatrics ◽  
Life Threatening ◽  
Etiologic Relationship

Because of the increasing emphasis on physical activity, sports medicine represents a growing proportion of medical care. Climatic heat stress, including heat stroke, is of sufficient concern that its preventability has been addressed by the American Academy of Pediatrics.1 Although heat stroke is defined by the triad of hyperpyrexia, anhydrosis, and altered mental status, the clinical course of these patients may include multiple complications.2-8 In this article we describe a previously unrecognized etiologic relationship between two of these complications, which may permit early identification and prevention of life-threatening consequences to heat stroke. Two cases of Gram-negative sepsis have been described in previously healthy young adults suffering from fatal exertional heat stroke.7,8

An Overview of Dementias

2012 ◽  
Vol 21 (3) ◽  
pp. 75-84
Author(s):  
Venkata Vijaya K. Dalai ◽  
Jason E. Childress ◽  
Paul E Schulz
Keyword(s):  
Clinical Presentation ◽  
Treatment Options ◽  
Current Treatment ◽  
Great Variability ◽  
Health Concern ◽  
Public Health Concern ◽  
Life Threatening ◽  
The Common ◽  
Neurodegenerative Dementias ◽  
Made In

Dementia is a major public health concern that afflicts an estimated 24.3 million people worldwide. Great strides are being made in order to better diagnose, prevent, and treat these disorders. Dementia is associated with multiple complications, some of which can be life-threatening, such as dysphagia. There is great variability between dementias in terms of when dysphagia and other swallowing disorders occur. In order to prepare the reader for the other articles in this publication discussing swallowing issues in depth, the authors of this article will provide a brief overview of the prevalence, risk factors, pathogenesis, clinical presentation, diagnosis, current treatment options, and implications for eating for the common forms of neurodegenerative dementias.

Computer-Aided Diagnosis in Jaundice: Comparison of Knowledge-based and Probabilistic Approaches

1996 ◽  
Vol 35 (01) ◽  
pp. 41-51 ◽  
Author(s):  
F. Molino ◽  
D. Furia ◽  
F. Bar ◽  
S. Battista ◽  
N. Cappello ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Information ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Clinical Documentation ◽  
Data Set ◽  
Knowledge Based ◽  
Number Of Patients ◽  
Support Tools ◽  
Aided Diagnosis

AbstractThe study reported in this paper is aimed at evaluating the effectiveness of a knowledge-based expert system (ICTERUS) in diagnosing jaundiced patients, compared with a statistical system based on probabilistic concepts (TRIAL). The performances of both systems have been evaluated using the same set of data in the same number of patients. Both systems are spin-off products of the European project Euricterus, an EC-COMACBME Project designed to document the occurrence and diagnostic value of clinical findings in the clinical presentation of jaundice in Europe, and have been developed as decision-making tools for the identification of the cause of jaundice based only on clinical information and routine investigations. Two groups of jaundiced patients were studied, including 500 (retrospective sample) and 100 (prospective sample) subjects, respectively. All patients were independently submitted to both decision-support tools. The input of both systems was the data set agreed within the Euricterus Project. The performances of both systems were evaluated with respect to the reference diagnoses provided by experts on the basis of the full clinical documentation. Results indicate that both systems are clinically reliable, although the diagnostic prediction provided by the knowledge-based approach is slightly better.

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