‘A patient act of adjustment’: Subjectivisation, adjectives and Jane Austen

2021 ◽  
pp. 096394702110232
Author(s):  
Victorina González-Díaz
Keyword(s):  
Historical Linguistic ◽  
Jane Austen ◽  
Standard English ◽  
Recent Scholarship ◽  
Starting Point ◽  
Word Senses ◽  
Previous Scholarship ◽  
Character Types

Previous scholarship on Jane Austen has often commented on the moral overtones of her lexical choices; more specifically, the fact that “incorrect” lexical innovations and fashionable words (i.e. new usages) tend to be deployed as part of the idiolect of foolish, gullible or morally reprehensible characters. By contrast, ethically sound characters normally move within the limits of established (‘old’) usages and the “correct” Standard English repertoire. Taking the historical linguistic concept of subjectivisation as starting point, this case-study explores the use of two adjectives ( lovely and nice) in Austen’s novels. The article (a) demonstrates that a straightforward socio-moral classification of ‘old’ and ‘new’ word-senses in Austen’s fiction is not fully adequate and (b) advocates, in line with recent scholarship, a more nuanced approach to the study of her fictional vocabulary, where old and new senses of a word (in this case, lovely and nice) move across the idiolect of different character-types for ironic, character- and plot-building purposes.

scholarly journals The visual multiplicity of films and its implications for audio description: A case study of the film What Dreams May Come

2013 ◽  
Author(s):  
Anna Maszerowska
Keyword(s):  
Detailed Analysis ◽  
Verbal Communication ◽  
Audio Description ◽  
Starting Point ◽  
The Many

Multilingualism in film is largely understood in terms of verbal communication. However, multiplicity also strongly manifests itself at the level of visual narration. The many codes within the cinematographic language encourage a broadening of the concept of multilingualism beyond the spectrum of words alone. This article examines the implications of visual multiplicity for media accessibility and, in particular, for audio description. Taking as a starting point Chaume’s (2004a, 2004b) classification of signifying codes of cinematographic language, we carry out a detailed analysis of the film What Dreams May Come (1998), discuss the composition of the filmic image and suggest strategies for achieving a successful descriptive integration of the visual and the verbal.

Chemometric Analysis for the Classification of some Groups of Drugs with Divergent Pharmacological Activity on the Basis of some Chromatographic and Molecular Modeling Parameters

2018 ◽  
Vol 21 (2) ◽  
pp. 125-137
Author(s):  
Jolanta Stasiak ◽  
Marcin Koba ◽  
Marcin Gackowski ◽  
Tomasz Baczek
Keyword(s):  
Correlation Analysis ◽  
Pharmacological Activity ◽  
Correlation Coefficients ◽  
Principal Component ◽  
Cardiovascular Drugs ◽  
New Drugs ◽  
Analgesic Drugs ◽  
Starting Point ◽  
Chromatographic Parameters

Aim and Objective: In this study, chemometric methods as correlation analysis, cluster analysis (CA), principal component analysis (PCA), and factor analysis (FA) have been used to reduce the number of chromatographic parameters (logk/logkw) and various (e.g., 0D, 1D, 2D, 3D) structural descriptors for three different groups of drugs, such as 12 analgesic drugs, 11 cardiovascular drugs and 36 “other” compounds and especially to choose the most important data of them. Material and Methods: All chemometric analyses have been carried out, graphically presented and also discussed for each group of drugs. At first, compounds’ structural and chromatographic parameters were correlated. The best results of correlation analysis were as follows: correlation coefficients like R = 0.93, R = 0.88, R = 0.91 for cardiac medications, analgesic drugs, and 36 “other” compounds, respectively. Next, part of molecular and HPLC experimental data from each group of drugs were submitted to FA/PCA and CA techniques. Results: Almost all results obtained by FA or PCA, and total data variance, from all analyzed parameters (experimental and calculated) were explained by first two/three factors: 84.28%, 76.38 %, 69.71% for cardiovascular drugs, for analgesic drugs and for 36 “other” compounds, respectively. Compounds clustering by CA method had similar characteristic as those obtained by FA/PCA. In our paper, statistical classification of mentioned drugs performed has been widely characterized and discussed in case of their molecular structure and pharmacological activity. Conclusion: Proposed QSAR strategy of reduced number of parameters could be useful starting point for further statistical analysis as well as support for designing new drugs and predicting their possible activity.

scholarly journals Assessment of health/functioning of older adults who consume psychoactive substances

2018 ◽  
Vol 71 (3) ◽  
pp. 942-950
Author(s):  
Vania Dias Cruz ◽  
Silvana Sidney Costa Santos ◽  
Jamila Geri Tomaschewski-Barlem ◽  
Bárbara Tarouco da Silva ◽  
Celmira Lange ◽  
...  
Keyword(s):  
Older Adults ◽  
Qualitative Case Study ◽  
International Classification Of Functioning ◽  
Psychoactive Substances ◽  
Systematic Observation ◽  
Health Functioning ◽  
Final Consideration ◽  
Theory Of Complexity

ABSTRACT Objective: To assess the health/functioning of the older adult who consumes psychoactive substances through the International Classification of Functioning, Disability and Health, considering the theory of complexity. Method: Qualitative case study, with 11 older adults, held between December 2015 and February 2016 in the state of Rio Grande do Sul, using interviews, documents and non-systematic observation. It was approved by the ethics committee. The analysis followed the propositions of the case study, using the complexity of Morin as theoretical basis. Results: We identified older adults who consider themselves healthy and show alterations - the alterations can be exacerbated by the use of psychoactive substances - of health/functioning expected according to the natural course of aging such as: systemic arterial hypertension; depressive symptoms; dizziness; tinnitus; harmed sleep/rest; and inadequate food and water consumption. Final consideration: The assessment of health/functioning of older adults who use psychoactive substances, guided by complex thinking, exceeds the accuracy limits to risk the understanding of the phenomena in its complexity.

Ein rechtsfreier Raum? Die legale Situation auf den Färöern im Spiegel der ‚Færeyinga saga‘

2020 ◽  
Vol 25 (1) ◽  
pp. 30-45
Author(s):  
Andreas Schmidt
Keyword(s):  
Cultural Norms ◽  
Old Icelandic ◽  
Power Politics ◽  
Starting Point ◽  
Narrative Literature ◽  
The Law

AbstractThe chapter argues for a more nuanced and empirically based understanding of the discourse on law and socio-cultural norms in Old Icelandic literature on the grounds of a narratological reading of ‘Færeyinga saga’ as a case study. It has often been claimed that Icelandic sources express an ideal of freedom based on communality as guaranteed by the law. By contrast, ‘Færeyinga saga’ represents a cynical discourse on power politics that renders law as an invariable concept obsolete and works solely on the principle that ‘might is right’. This cynicism, however, is presented in a form that leaves the narrative open to interpretation, showing that regardless of its possible dating, narrative literature can serve as a starting point for social discussion. Consequently, the discourse on law in medieval Iceland must be perceived as more polyphonic than has been allowed for by previous unifying readings in scholarship.

scholarly journals Sparse Autoencoder-based Multi-head Deep Neural Networks for Machinery Fault Diagnostics with Detection of Novelties

2021 ◽  
Vol 34 (1) ◽  
Author(s):  
Zhe Yang ◽  
Dejan Gjorgjevikj ◽  
Jianyu Long ◽  
Yanyang Zi ◽  
Shaohui Zhang ◽  
...  
Keyword(s):  
Fault Diagnosis ◽  
Supervised Classification ◽  
Deep Neural Networks ◽  
Activation Function ◽  
Reconstruction Error ◽  
Fine Tuning ◽  
Fault Diagnostics ◽  
Sparse Autoencoder

AbstractSupervised fault diagnosis typically assumes that all the types of machinery failures are known. However, in practice unknown types of defect, i.e., novelties, may occur, whose detection is a challenging task. In this paper, a novel fault diagnostic method is developed for both diagnostics and detection of novelties. To this end, a sparse autoencoder-based multi-head Deep Neural Network (DNN) is presented to jointly learn a shared encoding representation for both unsupervised reconstruction and supervised classification of the monitoring data. The detection of novelties is based on the reconstruction error. Moreover, the computational burden is reduced by directly training the multi-head DNN with rectified linear unit activation function, instead of performing the pre-training and fine-tuning phases required for classical DNNs. The addressed method is applied to a benchmark bearing case study and to experimental data acquired from a delta 3D printer. The results show that its performance is satisfactory both in detection of novelties and fault diagnosis, outperforming other state-of-the-art methods. This research proposes a novel fault diagnostics method which can not only diagnose the known type of defect, but also detect unknown types of defects.

‘More Product, Less Process’ (MPLP): An early printed book project

2021 ◽  
pp. 096100062110267
Author(s):  
Karen Attar
Keyword(s):  
18Th Century ◽  
The United States ◽  
Global Changes ◽  
Main Research ◽  
Advantages And Disadvantages ◽  
Main Research Interest ◽  
Printed Books ◽  
Starting Point ◽  
19Th And 20Th Century

This article addresses the challenge to make printed hidden collections known quickly without sacrificing ultimate quality. It takes as its starting point the archival mantra ‘More product, less process’ and explores its application to printed books, mindful of projects in the United States to catalogue 19th- and 20th-century printed books quickly and cheaply with the help of OCLC. A problem is lack of time or managerial inclination ever to return to ‘quick and dirty’ imports. This article is a case study concerning a collection of 18th-century English imprints, the Graveley Parish Library, at Senate House Library, University of London. Faced with the need to provide metadata as quickly as possible for digitisation purposes, Senate House Library decided, in contrast to its normal treatment of early printed books, to download records from the English Short Title Catalogue and amend them only very minimally before releasing them for public view, and to do this work from catalogue cards rather than the books themselves. The article describes the Graveley Parish collection, the project method’s rationale, and the advantages and disadvantages of sourcing the English Short Title Catalogue for metadata. It discusses the drawbacks of retrospective conversion (cataloguing from cards, not books): insufficient detail in some cases to identify the relevant book, and ignorance of the copy-specific elements of books which can constitute the main research interest. The method is compared against cataloguing similar books from photocopies of title pages, and retrospective conversion using English Short Title Catalogue is compared against retrospective conversion of early printed Continental books from cards using Library Hub Discover or OCLC. The control groups show our method’s effectiveness. The project succeeded by producing records fast that fulfilled their immediate purpose and simultaneously would obviously require revisiting. The uniform nature of the collection enabled the saving of time through global changes.

scholarly journals Exceptional nonrelativistic effective field theories with enhanced symmetries

2021 ◽  
Vol 2021 (2) ◽  
Author(s):  
Tomáš Brauner
Keyword(s):  
Effective Field Theories ◽  
Explicit Construction ◽  
Effective Field ◽  
Field Theories ◽  
Relativistic Case ◽  
Starting Point ◽  
Higher Power ◽  
Mere Presence ◽  
Spatial Rotations

Abstract We initiate the classification of nonrelativistic effective field theories (EFTs) for Nambu-Goldstone (NG) bosons, possessing a set of redundant, coordinate-dependent symmetries. Similarly to the relativistic case, such EFTs are natural candidates for “exceptional” theories, whose scattering amplitudes feature an enhanced soft limit, that is, scale with a higher power of momentum at long wavelengths than expected based on the mere presence of Adler’s zero. The starting point of our framework is the assumption of invariance under spacetime translations and spatial rotations. The setup is nevertheless general enough to accommodate a variety of nontrivial kinematical algebras, including the Poincaré, Galilei (or Bargmann) and Carroll algebras. Our main result is an explicit construction of the nonrelativistic versions of two infinite classes of exceptional theories: the multi-Galileon and the multi-flavor Dirac-Born-Infeld (DBI) theories. In both cases, we uncover novel Wess-Zumino terms, not present in their relativistic counterparts, realizing nontrivially the shift symmetries acting on the NG fields. We demonstrate how the symmetries of the Galileon and DBI theories can be made compatible with a nonrelativistic, quadratic dispersion relation of (some of) the NG modes.

scholarly journals The DWQ-EMR Embedded Tool to Enhance the Family Physician-Caregiver Connection: A Pilot Case Study

Geriatrics ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 29
Author(s):  
Kristina Marie Kokorelias ◽  
Einat Danieli ◽  
Sheila Dunn ◽  
Sid Feldman ◽  
David Patrick Ryan ◽  
...  
Keyword(s):  
Family Caregivers ◽  
Best Practice ◽  
Data Gathering ◽  
Family Physicians ◽  
Efficient Manner ◽  
Efficient Access ◽  
Increased Risk ◽  
Starting Point ◽  
To Receive

The number of family caregivers to individuals with dementia is increasing. Family physicians are often the first point of access to the health care system for individuals with dementia and their caregivers. Caregivers are at an increased risk of developing negative physical, cognitive and affective health problems themselves. Caregivers also describe having unmet needs to help them sustain care in the community. Family physicians are in a unique position to help support caregivers and individuals with dementia, but often struggle with keeping up with best practice dementia service knowledge. The Dementia Wellness Questionnaire was designed to serve as a starting point for discussions between caregivers and family physicians by empowering caregivers to communicate their needs and concerns and to enhance family physicians’ access to specific dementia support information. The DWQ aims to alert physicians of caregiver and patient needs. This pilot study aimed to explore the experiences of physicians and caregivers of people using the Questionnaire in two family medicine clinics in Ontario, Canada. Interviews with physicians and caregivers collected data on their experiences using the DWQ following a 10-month data gathering period. Data was analyzed using content analysis. Results indicated that family physicians may have an improved efficacy in managing dementia by having dementia care case specific guidelines integrated within electronic medical records. By having time-efficient access to tailored supports, family physicians can better address the needs of the caregiver–patient dyad and help support family caregivers in their caregiving role. Caregivers expressed that the Questionnaire helped them remember concerns to bring up with physicians, in order to receive help in a more efficient manner.

scholarly journals Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology

2021 ◽  
Vol 22 (14) ◽  
pp. 7292
Author(s):  
Luca Marsili ◽  
Jennifer Sharma ◽  
Alberto J. Espay ◽  
Alice Migazzi ◽  
Elhusseini Abdelghany ◽  
...  
Keyword(s):  
Spinocerebellar Ataxia Type ◽  
Niemann Pick Disease ◽  
Whole Exome ◽  
Heterozygous Variant ◽  
History Of ◽  
Ataxia Syndrome ◽  
Niemann Pick

The gold standard for classification of neurodegenerative diseases is postmortem histopathology; however, the diagnostic odyssey of this case challenges such a clinicopathologic model. We evaluated a 60-year-old woman with a 7-year history of a progressive dystonia–ataxia syndrome with supranuclear gaze palsy, suspected to represent Niemann–Pick disease Type C. Postmortem evaluation unexpectedly demonstrated neurodegeneration with 4-repeat tau deposition in a distribution diagnostic of progressive supranuclear palsy (PSP). Whole-exome sequencing revealed a new heterozygous variant in TGM6, associated with spinocerebellar ataxia type 35 (SCA35). This novel TGM6 variant reduced transglutaminase activity in vitro, suggesting it was pathogenic. This case could be interpreted as expanding: (1) the PSP phenotype to include a spinocerebellar variant; (2) SCA35 as a tau proteinopathy; or (3) TGM6 as a novel genetic variant underlying a SCA35 phenotype with PSP pathology. None of these interpretations seem adequate. We instead hypothesize that impairment in the crosslinking of tau by the TGM6-encoded transglutaminase enzyme may compromise tau functionally and structurally, leading to its aggregation in a pattern currently classified as PSP. The lessons from this case study encourage a reassessment of our clinicopathology-based nosology.

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