A nanosized rigid spherical inclusion with interfacial diffusion and sliding

2017 ◽  
Vol 23 (7) ◽  
pp. 1049-1060
Author(s):  
Xu Wang
Keyword(s):  
Steady State ◽  
Stress Field ◽  
Normal Stress ◽  
Spherical Inclusion ◽  
Surface Elasticity ◽  
Relaxation Times ◽  
Imperfect Interface ◽  
Time Dependent ◽  
Interfacial Diffusion ◽  
The Matrix

We examine the time-dependent deformations around a nanosized rigid spherical inclusion in an infinite elastic matrix under uniaxial tension at infinity. The elastic matrix is first endowed with separate Gurtin–Murdoch surface elasticity. Furthermore, interfacial diffusion and sliding both occur on the inclusion–matrix interface. Closed-form expressions of the time-dependent displacements and stresses in the matrix are derived by using Papkovich–Neuber displacement potentials. A concise and elegant expression of the steady-state normal stress on the surface of the inclusion is also obtained. It is seen that the displacements and stresses in the matrix evolve with two relaxation times which are reliant on three size-dependent parameters, one from surface elasticity and the other two from interfacial diffusion and sliding. Numerical results are presented to demonstrate the influence of surface elasticity on the relaxation times and on the stress distribution near the inclusion. It is observed that the surface elasticity can alter the nature of the steady state normal stress on the surface of the inclusion from tension to compression. When the radius of the inclusion is not greater than the ratio of residual surface tension to remote tension, the steady state normal stress on the surface of the inclusion is always compressive. The related problem of a nanosized rigid spherical inclusion with a spring-type imperfect interface is also solved. We find that it is feasible to design a neutral spherical inclusion that does not disturb a prescribed uniform uniaxial stress field or even any uniform stress field outside the inclusion through a judicious choice of the four imperfect interface parameters.

A Spherical Inclusion with Inhomogeneous Interface in Conduction

2003 ◽  
Vol 19 (1) ◽  
pp. 1-8
Author(s):  
T. Chen ◽  
C. H. Hsieh ◽  
P. C. Chuang
Keyword(s):  
Infinite Number ◽  
Effective Conductivity ◽  
Spherical Inclusion ◽  
Cone Angle ◽  
Imperfect Interface ◽  
Infinite Matrix ◽  
Algebraic Equations ◽  
Legendre Series ◽  
Linear Set ◽  
The Matrix

ABSTRACTA series solution is presented for a spherical inclusion embedded in an infinite matrix under a remotely applied uniform intensity. Particularly, the interface between the inclusion and the matrix is considered to be inhomegeneously bonded. We examine the axisymmetric case in which the interface parameter varies with the cone angle θ. Two kinds of imperfect interfaces are considered: an imperfect interface which models a thin interphase of low conductivity and an imperfect interface which models a thin interphase of high conductivity. We show that, by expanding the solutions of terms of Legendre polynomials, the field solution is governed by a linear set of algebraic equations with an infinite number of unknowns. The key step of the formulation relies on algebraic identities between coefficients of products of Legendre series. Some numerical illustrations are presented to show the correctness of the presented procedures. Further, solutions of the boundary-value problem are employed to estimate the effective conductivity tensor of a composite consisting of dispersions of spherical inclusions with equal size. The effective conductivity solely depends on one particular constant among an infinite number of unknowns.

scholarly journals Picosecond-Duration Vibrational Relaxation Kinetics in the Excited S1 State of Perylene and Anthracene Molecules

1983 ◽  
Vol 3 (1-6) ◽  
pp. 249-261 ◽  
Author(s):  
A. Freiberg ◽  
T. Tamm ◽  
K. Timpmann
Keyword(s):  
Steady State ◽  
Luminescence Spectrum ◽  
Vibrational Relaxation ◽  
Vibrational Energy ◽  
Streak Camera ◽  
Relaxation Times ◽  
Temporal Behavior ◽  
Vibrational Energy Relaxation ◽  
The Matrix ◽  
Measured Relaxation

We present and discuss the results of a direct observation of the picosecond range temporal behavior of vibronic lines in the luminescence spectrum of the matrix-isolated perylene and anthracene molecules. A novel subtractive dispersion mount of monochromators in conjunction with the synchroscan streak camera has been used. From spectrochronograms measured at different excitation wavelengths the vibrational energy relaxation times have been obtained. These are in the range of 20–30 ps and are most probably determined by the existence of the phonon bath of the matrix. A comparison of the measured relaxation constants with those estimated from the steady-state hot luminescence spectrum has been made.

An Analytical Model for Dynamic Wear

1989 ◽  
Vol 111 (3) ◽  
pp. 468-474 ◽  
Author(s):  
Ji-Yi Lin ◽  
H. S. Cheng
Keyword(s):  
Steady State ◽  
Stress Field ◽  
Wear Rate ◽  
Frictional Force ◽  
Wear Behavior ◽  
Time Dependent ◽  
Material Strength ◽  
Wear Model ◽  
Asperity Contacts ◽  
Dynamic Wear

A wear model which permits the wear rate to be dependent on time is introduced to study the dynamic wear behavior observed in practice. In this model, it is postulated that the wear rate is proportional to a forcing term, I, which is contributed by the stress field induced by the frictional force at the asperity contacts; and inversely proportional to a wear resisting term, S, which is related to the material antiwear strength near the surface. One of the important characteristics of the dynamic wear model is that both I and S are now time dependent or wear dependent because when wear progresses the material strength at various layers would change and the stress field would also change as a result of the change of surface topography. Using this dynamic wear model, it is shown that the commonly observed running-in, steady-state, or accelerated wear phenomena can be explained.

The Elastic Inclusion With a Sliding Interface

1984 ◽  
Vol 51 (2) ◽  
pp. 308-310 ◽  
Author(s):  
T. Mura ◽  
R. Furuhashi
Keyword(s):  
Stress Field ◽  
Shear Deformation ◽  
Spherical Inclusion ◽  
Elastic Inclusion ◽  
Ellipsoidal Inclusion ◽  
Spheroidal Inclusion ◽  
Sliding Interface ◽  
Shear Traction ◽  
The Matrix ◽  
Invariant Transformation

It is found that when an ellipsoidal inclusion undergoes a shear eigenstrain and the inclusion is free to slip along the interface, the stress field vanishes everywhere in the inclusion and the matrix. It is assumed in the analysis that the inclusion interface cannot sustain any shear traction. There exists a shear deformation that transforms an ellipsoid into the identical ellipsoid without changing its orientation (ellipsoid invariant transformation). This is not true, however, for a spheroidal inclusion. The amount of slip and the associated stress field are calculated for a spherical inclusion for a given uniform eigenstrain εij*.

scholarly journals Expression of VEGF-A Signaling Pathway in Cartilage of ACLT-induced Osteoarthritis Mouse Model

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jia-jia Qian ◽  
Qi Xu ◽  
Wei-min Xu ◽  
Ren Cai ◽  
Gui-cheng Huang
Keyword(s):  
Signaling Pathway ◽  
Cruciate Ligament ◽  
Time Dependent ◽  
Pathological Changes ◽  
The Matrix ◽  
Vegfr2 Signaling ◽  
Cox 2 ◽  
Anterior Cruciate ◽  
A Disintegrin And Metalloproteinase ◽  
Safranin O

Abstract Background Anterior cruciate ligament transection surgery (ACLT)-induced OA model was often used to investigate the molecular mechanism of knee osteoarthritis (KOA). Researches have shown that vascular endothelial growth factor (VEGF) played an important role in OA. The present study aimed to investigate the pathological changes after ACLT surgery and reveal the expression characteristics of the VEGF-A/VEGFR2 signaling pathway in this model. Methods Moderate KOA model was established by ACLT, and 1, 2, 4, 8, and 12 weeks after surgery, hematoxylin-eosin (HE) and Safranin-O(S-O) staining were used to detect the pathological changes in mouse knee cartilage, and the matrix biomarkers A Disintegrin and Metalloproteinase with Thrombospondin Motifs 5(ADAMTS5), Collagen II (COL-II) were detected using immunohistochemistry (IHC), CD31 was detected by immunofluorescence (IF) to show the vascular invasion in cartilage, and proteins expression of VEGF-A pathway were detected by Western blot (WB). Meanwhile, the inflammatory biomarkers cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in cartilage were detected by WB. Results ACLT surgery can lead to degeneration of cartilage in mice, and the characteristics of the lesion were time-dependent. The ADAMTS5-positive cells increased while COL-II decreased in OA cartilage with time, and new blood vessels labeled by CD31 can be seen from 1 week in OA cartilage, and increased in 8 and 12 weeks. The expression of VEGF-A, VEGFR2, COX-2, and iNOS were higher than control groups, which were basically consistent with the degree of osteoarthritis. Conclusions The degenerative degree of articular cartilage was time-dependent; angiogenesis and inflammation were important pathological changes of cartilage in KOA. The expression of the VEGF-A/VEGFR2 signaling pathway was basically correlated with the degree of KOA.

scholarly journals Ground- and excited-state characteristics in photovoltaic polymer N2200

RSC Advances ◽  
2021 ◽  
Author(s):  
Guanzhao Wen ◽  
Xianshao Zou ◽  
Rong Hu ◽  
Jun Peng ◽  
Zhifeng Chen ◽  
...  
Keyword(s):  
Density Functional Theory ◽  
Excited State ◽  
Steady State ◽  
Excited States ◽  
Density Functional ◽  
Density Functional Theory Calculations ◽  
Time Dependent ◽  
Functional Theory ◽  
Time Resolved ◽  
Dependent Density

Ground- and excited-states properties of N2200 have been studied by steady-state and time-resolved spectroscopies as well as time-dependent density functional theory calculations.

scholarly journals A Numerical Approach for Evaluating the Time-Dependent Distribution of a Quasi Birth-Death Process

2021 ◽  
Author(s):  
Michel Mandjes ◽  
Birgit Sollie
Keyword(s):  
Continuous Time ◽  
Real Life ◽  
Numerical Approach ◽  
Time Dependent ◽  
Death Process ◽  
Continuous Time Markov Chain ◽  
Likelihood Estimator ◽  
Real Life Data ◽  
The Matrix ◽  
Birth Death

AbstractThis paper considers a continuous-time quasi birth-death (qbd) process, which informally can be seen as a birth-death process of which the parameters are modulated by an external continuous-time Markov chain. The aim is to numerically approximate the time-dependent distribution of the resulting bivariate Markov process in an accurate and efficient way. An approach based on the Erlangization principle is proposed and formally justified. Its performance is investigated and compared with two existing approaches: one based on numerical evaluation of the matrix exponential underlying the qbd process, and one based on the uniformization technique. It is shown that in many settings the approach based on Erlangization is faster than the other approaches, while still being highly accurate. In the last part of the paper, we demonstrate the use of the developed technique in the context of the evaluation of the likelihood pertaining to a time series, which can then be optimized over its parameters to obtain the maximum likelihood estimator. More specifically, through a series of examples with simulated and real-life data, we show how it can be deployed in model selection problems that involve the choice between a qbd and its non-modulated counterpart.

scholarly journals Determinants of mRNA stability in Dictyostelium discoideum amoebae: differences in poly(A) tail length, ribosome loading, and mRNA size cannot account for the heterogeneity of mRNA decay rates.

1988 ◽  
Vol 8 (5) ◽  
pp. 1957-1969 ◽  
Author(s):  
R A Shapiro ◽  
D Herrick ◽  
R E Manrow ◽  
D Blinder ◽  
A Jacobson
Keyword(s):  
Steady State ◽  
Dictyostelium Discoideum ◽  
Mrna Decay ◽  
Decay Rates ◽  
Time Dependent ◽  
Translational Efficiency ◽  
Cdna Clones ◽  
Dependent Manner ◽  
Significant Difference ◽  
Kinetics Of

As an approach to understanding the structures and mechanisms which determine mRNA decay rates, we have cloned and begun to characterize cDNAs which encode mRNAs representative of the stability extremes in the poly(A)+ RNA population of Dictyostelium discoideum amoebae. The cDNA clones were identified in a screening procedure which was based on the occurrence of poly(A) shortening during mRNA aging. mRNA half-lives were determined by hybridization of poly(A)+ RNA, isolated from cells labeled in a 32PO4 pulse-chase, to dots of excess cloned DNA. Individual mRNAs decayed with unique first-order decay rates ranging from 0.9 to 9.6 h, indicating that the complex decay kinetics of total poly(A)+ RNA in D. discoideum amoebae reflect the sum of the decay rates of individual mRNAs. Using specific probes derived from these cDNA clones, we have compared the sizes, extents of ribosome loading, and poly(A) tail lengths of stable, moderately stable, and unstable mRNAs. We found (i) no correlation between mRNA size and decay rate; (ii) no significant difference in the number of ribosomes per unit length of stable versus unstable mRNAs, and (iii) a general inverse relationship between mRNA decay rates and poly(A) tail lengths. Collectively, these observations indicate that mRNA decay in D. discoideum amoebae cannot be explained in terms of random nucleolytic events. The possibility that specific 3'-structural determinants can confer mRNA instability is suggested by a comparison of the labeling and turnover kinetics of different actin mRNAs. A correlation was observed between the steady-state percentage of a given mRNA found in polysomes and its degree of instability; i.e., unstable mRNAs were more efficiently recruited into polysomes than stable mRNAs. Since stable mRNAs are, on average, "older" than unstable mRNAs, this correlation may reflect a translational role for mRNA modifications that change in a time-dependent manner. Our previous studies have demonstrated both a time-dependent shortening and a possible translational role for the 3' poly(A) tracts of mRNA. We suggest, therefore, that the observed differences in the translational efficiency of stable and unstable mRNAs may, in part, be attributable to differences in steady-state poly(A) tail lengths.

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