Do Personality Traits Predict Functional Impairment and Quality of Life in Adult ADHD? A Controlled Study

2015 ◽  
Vol 23 (1) ◽  
pp. 12-21 ◽  
Author(s):  
J. Allison He ◽  
Kevin M. Antshel ◽  
Joseph Biederman ◽  
Stephen V. Faraone
Keyword(s):  
Quality Of Life ◽  
Personality Traits ◽  
Social Adjustment ◽  
Functional Impairment ◽  
Negative Binomial ◽  
Self Report ◽  
Controlled Study ◽  
Adhd Symptoms ◽  
Functional Impairments

Objective: To examine the association of personality traits and characteristics on quality of life and functioning in adults with ADHD. Method: Participants were adults with ( n = 206) and without ADHD ( n = 123) who completed the Temperament and Character Inventory (TCI), the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), and the Social Adjustment Scale–Self-Report (SAS-SR). Participants also provided information on academic, motor vehicle operation, legal, social, familial, and occupational functioning. Outcomes were examined using stepwise linear regression, logistic regression (for binary outcomes), and negative binomial regression (for count outcomes) controlling for ADHD symptoms, psychiatric comorbidity, and executive dysfunction. Results: Adults with ADHD significantly differed from controls across nearly all TCI personality domains. On average, adults with ADHD endorsed more novelty seeking, harm avoidance, and self-transcendence, and less reward dependence, persistence, self-directedness, and cooperativeness. Personality traits and characteristics, especially self-directedness, significantly predicted functional impairments even after controlling for ADHD symptoms, executive function deficits, and current psychiatric comorbidities. Conclusion: In adults with ADHD, personality traits exert unique associations on quality of life and functional impairment across major life domains, beyond the relations expected of and associated with ADHD symptoms and other associated psychiatric conditions and cognitive vulnerabilities. Addressing personality traits in adults with ADHD may lead to improvements in quality of life and reductions in functional impairment.

Quality of life in children and adolescents with obsessive-compulsive disorder: The Pediatric Quality of Life Enjoyment and Satisfaction Questionnaire (PQ-LES-Q)

2019 ◽  
Vol 83 (4) ◽  
pp. 377-397 ◽  
Author(s):  
Brian A. Zaboski ◽  
Alexandra Gilbert ◽  
Rebecca Hamblin ◽  
Jessica Andrews ◽  
Amaya Ramos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Functional Impairment ◽  
Intensive Treatment ◽  
Self Report ◽  
Obsessive Compulsive ◽  
Satisfaction Questionnaire ◽  
Compulsive Disorder

The current study examined quality of life (QOL) and its clinical correlates among 225 intensive treatment-seeking children and adolescents with obsessive-compulsive disorder (OCD) using the Pediatric Quality of Life Enjoyment and Satisfaction Questionnaire (PQ-LES-Q). Youth completed the PQ-LES-Q along with self-report measures assessing functional impairment, anxiety sensitivity, OCD symptoms, nonspecific anxiety, depression, and social anxiety. Parents completed measures on their child's anxiety, the presence of inattention/hyperactivity, depression, functional impairment, and frequency of family accommodation of symptoms. Contrary to expectation, child-reported OCD symptoms did not significantly predict QOL; however, lower overall QOL was strongly associated with the presence of comorbid major depressive disorder (g=3D −0.76) and slightly related to comorbid social phobia (g=3D −0.36). These results suggest that assessing and addressing comorbid conditions in the treatment of youth with OCD is an important component of intensive treatment.

The effects of atomoxetine on emotional control in adults with ADHD: An integrated analysis of multicenter studies

2015 ◽  
Vol 30 (4) ◽  
pp. 511-520 ◽  
Author(s):  
P. Asherson ◽  
S. Stes ◽  
M. Nilsson Markhed ◽  
L. Berggren ◽  
P. Svanborg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Effect Size ◽  
Adult Adhd ◽  
Self Report ◽  
Integrated Analysis ◽  
Emotional Control ◽  
Adhd Symptoms ◽  
Multicenter Studies ◽  
Small Effect Size

AbstractPurpose:To investigate the effects of atomoxetine on emotional control in adults with ADHD.Methods:We performed an integrated analysis using individual patient data pooled from three Eli Lilly-sponsored studies. An integrated analysis can be viewed as a meta-analysis of individual patient-level data, rather than study-level summary data.Results:Two populations were identified: a large sample of patients with pre-treatment baseline data (the “overall population”; n = 2846); and a subset of these patients with placebo-controlled efficacy data from baseline to 10 or 12 weeks after initiating treatment (the “placebo-controlled population”; n = 829). At baseline, in the overall population, ∼50% of ADHD patients had BRIEF-AS (Behavior Rating Inventory of Executive Function-Adult Version Self-Report) Emotional control subscores between 21 and 30, compared with ∼10% of normative subjects in the BRIEF-A manual. At endpoint, in the placebo-controlled population, atomoxetine led to a small (effect size 0.19) but significant (P = 0.013) treatment effect for emotional control. The effect size was 0.32 in patients with BRIEF-AS Emotional control scores > 20 at baseline. Improvements in emotional control correlated with improvements in the core ADHD symptoms and quality-of-life.Discussion:As deficient emotional control is associated with impaired social, educational and occupational functioning over and above that explained by core ADHD symptoms alone, improvements in emotional control may be clinically relevant.Conclusion:At baseline, adults with ADHD were more likely to have impaired emotional control than normative subjects. In the adult ADHD patients, atomoxetine treatment was associated with improvements in emotional control, as well as in core ADHD symptoms and quality-of-life.

Functional and psychosocial impairment in adults with undiagnosed ADHD

2006 ◽  
Vol 37 (1) ◽  
pp. 97-107 ◽  
Author(s):  
STEPHEN L. ABLE ◽  
JOSEPH A. JOHNSTON ◽  
LENARD A. ADLER ◽  
RALPH W. SWINDLE
Keyword(s):  
Quality Of Life ◽  
Educational Attainment ◽  
Functional Impairment ◽  
Adult Adhd ◽  
Self Report ◽  
Administrative Claims ◽  
Psychosocial Impairment ◽  
Care Plans ◽  
Lower Educational Attainment

Background. Identify a group of adults with ‘undiagnosed’ attention deficit hyperactivity disorder (ADHD) and compare their personal and family medical histories, psychosocial profiles, functional impairment and quality of life with non-ADHD controls. Additionally, compare adults with undiagnosed and diagnosed ADHD to investigate possible reasons why the undiagnosed avoid clinical detection.Method. ICD-9 codes for ADHD in administrative claims records and responses to a telephone-administered adult ADHD screener [the Adult ADHD Self-Report Scale (ASRS)] were used to classify approximately 21000 members of two large managed health-care plans as ‘undiagnosed’ (no coded diagnosis; ASRS positive) or ‘non-ADHD’ controls (no coded diagnosis; ASRS negative). Patients identified as ‘undiagnosed’ ADHD were compared with samples of non-ADHD controls and ‘diagnosed’ ADHD patients (ICD-9 coded ADHD diagnoses) on the basis of demographics, socio-economic status, past and present mental health conditions, and self-reported functional and psychosocial impairment and quality of life.Results. A total of 752 ‘undiagnosed’ ADHD subjects, 199 ‘non-ADHD’ controls and 198 ‘diagnosed’ ADHD subjects completed a telephone interview. Overall, the ‘undiagnosed’ ADHD cohort demonstrated higher rates of co-morbid illness and greater functional impairment than ‘non-ADHD’ controls, including significantly higher rates of current depression, and problem drinking, lower educational attainment, and greater emotional and interpersonal difficulties. ‘Undiagnosed’ ADHD subjects reported a different racial composition and lower educational attainment than ‘diagnosed’ ADHD subjects.Conclusion. Individuals with ‘undiagnosed’ ADHD manifest significantly greater functional and psychosocial impairment than those screening negative for the disorder, suggesting that ADHD poses a serious burden to adults even when clinically unrecognized.

scholarly journals Emotional Dysregulation And Quality of Life In Young Adults With ADHD- A Cross Sectional Study

2021 ◽  
Author(s):  
Maayan Ben Dor Cohen ◽  
Eran Eldar ◽  
Adina Maeir ◽  
Mor Nahun
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Attention Deficit ◽  
Adult Adhd ◽  
Emotional Dysregulation ◽  
Self Report ◽  
Adhd Group ◽  
Adhd Symptoms ◽  
Cross Sectional

Abstract Objective: Attention Deficit Hyperactivity Disorder (ADHD) is associated with emotional dysregulation (ED) and impaired quality of life (QoL). However, the role of ED in explaining the relationship between ADHD and QoL is unclear. The purpose of the present study was to do so in a sample of non-referred young adults with and without ADHD.Method: The study design was cross-sectional. A non-clinical sample of 62 young adults with ADHD (mean age = 24.86 years, SD = 3.25) and 69 controls (mean age = 23.84 years, SD = 2.59) were recruited. The Adult ADHD Quality-of-Life scale was used to measure QoL; The Adult ADHD Self-Report Scale was used to measure ADHD symptoms. The Self-Report Wender-Reimherr Adult Attention Deficit Disorder Scale and the Difficulties in Emotion Regulation Scale were used to measure ED. Group differences on all measures were tested using univariate and multivariate analyses of covariance, while controlling for age. Univariate analyses of variance were conducted to investigate the possible effect of medication on all outcome measures in the ADHD group. Finally, a moderation analysis was used in order to examine the impact of ED on QoL beyond that accounted for by ADHD symptoms.Results: Both QoL and ED were significantly worse for the ADHD group compared to the control group. The medication status of the ADHD group participants had no significant effect on the level of ADHD symptoms, ED or QoL. ED moderated the effect of ADHD symptoms on QoL for the ADHD group.Conclusion: The findings support the centrality of ED in ADHD and its crucial influence on QoL. Young adults with ADHD and high levels of ED are at risk for aversive impact on their well-being regardless of their ADHD symptoms level.

Quality of Life Among Children and Adolescents With Tourette Disorder and Comorbid ADHD: A Clinical Controlled Study

2018 ◽  
Vol 23 (8) ◽  
pp. 817-827 ◽  
Author(s):  
Seda Erbilgin Gün ◽  
Ayse Kilincaslan
Keyword(s):  
Quality Of Life ◽  
Family Functioning ◽  
Rating Scale ◽  
Controlled Study ◽  
Adhd Group ◽  
Adhd Symptoms ◽  
Family Assessment Device ◽  
Tic Severity ◽  
Comorbid Adhd

Objective: To examine (a) the quality of life (QOL) in children with Tourette’s disorder (TD) and ADHD (TD + ADHD) compared with ADHD without tics (ADHD alone) and (b) the effects of the severity of tics, ADHD symptoms, comorbid diagnoses, and family functioning on QOL. Method: The assessments included the Kiddie-Schedule for Affective Disorders and Schizophrenia, Yale Global Tic Severity Scale, ADHD Rating Scale, Pediatric Quality of Life Inventory, and Family Assessment Device. Results: The TD + ADHD group had poorer psychosocial QOL. Agreement between child and parent ratings was higher in the TD + ADHD group, and children reported higher scores than their parents in both groups. Severity of tics and ADHD symptoms had stronger negative associations with parent-reported than child-reported QOL. Significant positive correlations were detected between QOL and family functioning in both groups. Conclusion: Children with TD + ADHD have lower QOL than their peers with ADHD alone. Family functioning seems to affect QOL in both groups.

Aspects Of Quality Of Life In Depression

2016 ◽  
Vol 33 (S1) ◽  
pp. S421-S422
Author(s):  
M.G. Puiu ◽  
M.C. Manea ◽  
I.A. Andrei ◽  
A.M. Cristache ◽  
A.A. Frunza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Social Adjustment ◽  
Rating Scale ◽  
Antidepressant Treatment ◽  
Statistical Significance ◽  
International Classification Of Diseases ◽  
Social Adaptation ◽  
Self Report

IntroductionThe quality of life in patients with depression may be a measure of the efficiency of its management. Although quality of life is a subjective concept, difficult to assess, it may be reflected by the degree of social adaptation and the individual's level of functioning.ObjectiveThe study evaluates the time evolution of depressive symptoms and of some parameters attesting the quality of life in patients diagnosed with depression who are on antidepressant treatment.AimsHighlighting the evolution in time of depressive symptoms and patients’ perceptions on some aspects of quality of life.MethodsThere were included 23 patients who met the criteria of depressive episode, single or within recurrent depressive disorder, according to the International Classification of Diseases (ICD-10-AM), requiring antidepressant treatment. Subjects were evaluated at baseline and after 12 weeks of treatment using the Hamilton Rating Scale for Depression (HAMD), Sheehan disability scale (SDS), Social Adjustment Scale – Self-report (SASS).ResultsStatistically significant decrease in mean HAMD scores was observed in the second administration. There were registered statistically significant differences of scores obtained in the two administrations for the 17 items of the SASS scale. Correlations with statistical significance between HAMD scores and some of the SDS areas were observed.ConclusionsResults showed a favorable course of depressive symptoms while under treatment and differences in time of subjects’ perception on several aspects evaluated on SASS for the group studied. Correlations with statistical significance between HAMD scores and some SDS areas were observed.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Effects of Tracheostomy on Well-being and Body-Image Perceptions

2005 ◽  
Vol 133 (3) ◽  
pp. 366-371 ◽  
Author(s):  
Dror Gilony ◽  
Dalia Gilboa ◽  
Tzvia Blumstein ◽  
Havi Murad ◽  
Yoav P. Talmi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Image ◽  
Personality Traits ◽  
Satisfaction With Life ◽  
Well Being ◽  
Satisfaction With Life Scale ◽  
Controlled Study ◽  
Tertiary Referral Center ◽  
Related Quality

OBJECTIVE: Quality of life after tracheostomy was addressed by measuring its impact on well being and body image perceptions. STUDY DESIGN AND SETTING: A controlled study in a laryngotracheal clinic of a tertiary referral center. Three groups were studied: 24 cannulated, 19 decannulated, and 20 noncannulated patients. They filled up 3 conventional questionnaires. RESULTS: (1) Satisfaction-with-life scale: reduced scores were detected between cannulated and noncannulated patients. (2) Personality traits: neuroticism and extroversion: no differences were noted. (3) Body cathexis scale: both cannulated and decannulated patients scored less than noncannulated. In tracheostomy-specific issues, decannulated patients scored better than cannulated patients. CONCLUSIONS: Reduced scores after tracheostomy indicate an overall diminished quality of life. These changes correlate with personality traits. Decannulated patients exhibited only slight improvement indicating an incomplete psychosocial recovery. SIGNIFICANCE: This is the first report on tracheostomy related quality of life in noncancer patients conducted with specific psychological questionnaires.

scholarly journals M233. EXPERIENTIAL NEGATIVE SYMPTOMS ARE MORE PREDICTIVE OF REAL-LIFE FUNCTIONAL OUTCOME THAN EXPRESSIVE NEGATIVE SYMPTOMS IN CLINICAL HIGH-RISK STATES

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S225-S225
Author(s):  
Louise Birkedal Glenthoej ◽  
Tina Dam Kristensen ◽  
Christina Wenneberg ◽  
Carsten Hjorthøj ◽  
Merete Nordentoft
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
Functional Outcome ◽  
Negative Symptoms ◽  
Real Life ◽  
Self Report ◽  
Functional Impairments ◽  
Life Functioning

Abstract Background Negative symptoms are key features of schizophrenia spectrum disorders that are linked to psychosis development and functional impairments. This study investigated the predictive power of negative symptoms domains on multiple aspects of real-life functional outcome in individuals at Ultra High-Risk (UHR) for psychosis. Methods A total of 146 UHR individuals were enrolled in a randomised, clinical trial. This study reports on analyses secondary to the RCT. The UHR individuals were assessed at baseline with the Scale for the Assessment of Negative Symptoms (SANS) encompassing the four domains of affect, alogia, avolition, and anhedonia. Functioning measures, comprising overall-, social-, and role functioning, self-report social functioning, and quality of life, were obtained at 12-month follow-up. Regression analyses elucidated on the relationship between the four negative symptom domains and functional outcomes. Results The aspects of negative symptoms most predictive of real-life functioning at 12-month follow-up were anhedonia and avolition explaining 6–19% of the variance on the functional outcome measures. The finding was maintained when controlling for the effect of neurocognition, antipsychotic medication, and depressive symptoms. Discussion Our study finds experiential negative symptoms to predict multiple areas of real-life functioning and quality of life, while expressive negative symptoms exert a modest influence on the functional prognosis of UHR individuals. Hence, experiential negative symptoms (such as motivational deficits and asociality) may constitute an important treatment target in intervention approaches aimed at enhancing the functional outcome of UHR individuals.

Cathartic Effect of Suicide Attempts Not Limited to Depression

Crisis ◽  
2003 ◽  
Vol 24 (2) ◽  
pp. 73-78 ◽  
Author(s):  
Yves Sarfati ◽  
Blandine Bouchaud ◽  
Marie-Christine Hardy-Baylé
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Personality Traits ◽  
Rating Scales ◽  
Suicide Attempts ◽  
World Health ◽  
Life Questionnaire ◽  
Short Term

Summary: The cathartic effect of suicide is traditionally defined as the existence of a rapid, significant, and spontaneous decrease in the depressive symptoms of suicide attempters after the act. This study was designed to investigate short-term variations, following a suicide attempt by self-poisoning, of a number of other variables identified as suicidal risk factors: hopelessness, impulsivity, personality traits, and quality of life. Patients hospitalized less than 24 hours after a deliberate (moderate) overdose were presented with the Montgomery-Asberg Depression and Impulsivity Rating Scales, Hopelessness scale, MMPI and World Health Organization's Quality of Life questionnaire (abbreviated versions). They were also asked to complete the same scales and questionnaires 8 days after discharge. The study involved 39 patients, the average interval between initial and follow-up assessment being 13.5 days. All the scores improved significantly, with the exception of quality of life and three out of the eight personality traits. This finding emphasizes the fact that improvement is not limited to depressive symptoms and enables us to identify the relative importance of each studied variable as a risk factor for attempted suicide. The limitations of the study are discussed as well as in particular the nongeneralizability of the sample and setting.

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