Obesity-Related Parameters Are Associated With Blood Pressure in Palestinian Children

Hypertension has been established as a common health condition in young people. Most studies have focused on the impact of body mass index (BMI), but the relationships between body composition parameters and blood pressure in Palestinian children has not previously been investigated. We aimed to analyze the prevalence of overweight/obesity and elevated blood pressure/hypertension and investigate the associations among obesity-related parameters, including anthropometric and body composition markers and blood pressure levels in a population of 971 Palestinian school children (50% girls; mean age 10.3 ± 1.1 years). Anthropometric measurements including height, waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), and waist to height ratio (WHtR) were assessed. A body composition analyzer was used to measure body weight, fat mass, and fat-free mass. Blood pressure including systolic (SBP), diastolic (DBP) and mean arterial pressure (MAP) were measured using a Dinamap vital signs monitor. The prevalence of overweight/obesity was 25.3% in the girls and 23.1% in the boys. 26.3% of the children had elevated systolic blood pressure, or systolic hypertension; whereas 23.4% had elevated diastolic blood pressure, or diastolic hypertension. All obesity-related variables, with the exception of WHR and WHtR, showed statistical differences among the normotension, elevated blood pressure and hypertension groups for systolic and diastolic blood pressure ( p < 0.05). Children with elevated blood pressure or hypertension had significantly higher weight, BMI, WC, HC, fat mass, and fat-free mass values compared to participants with normotension, supporting the direct association between obesity and hypertension in this population. Weight-reduction interventions are essential for reducing the prevalence of childhood hypertension in Palestinian children.

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Distress tolerance moderates the relationship between anger experience and elevated blood pressure

South African Journal of Psychology ◽

10.1177/0081246319832540 ◽

2019 ◽

Vol 50 (1) ◽

pp. 39-53 ◽

Cited By ~ 1

Author(s):

Maria Chidi C Onyedibe ◽

Peace N Ibeagha ◽

Ike E Onyishi

Keyword(s):

Blood Pressure ◽

Diastolic Blood Pressure ◽

Distress Tolerance ◽

Diastolic Pressure ◽

Short Form ◽

University Teaching ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Anger Experience ◽

The Relationship

Previous studies have linked anger to elevated blood pressure. However, the nature of the association between anger and elevated blood pressure is unclear. This study is aimed at investigating the moderating effect of distress tolerance on the relationship between anger experience and elevated blood pressure. A total of 310 patients drawn from a university teaching hospital in southeast Nigeria participated in this study. They comprised 156 men and 154 women who were aged between 20 and 80 years (mean age = 50.45). Participants responded to the measures of distress tolerance and Novaco Anger Inventory—Short Form. The blood pressures of the participants were obtained with sphygmomanometer and stethoscope. The results of the hierarchical multiple regression analysis indicated that anger experience significantly predicted both systolic and diastolic blood pressure. The results also showed that distress tolerance was a significant predictor of systolic and diastolic blood pressure. Distress tolerance moderated the relationship between anger experience and systolic and diastolic blood pressure. The relationships between anger and systolic and diastolic pressure were stronger for patients with low distress tolerance compared to patients with high distress tolerance. It is recommended that psychological interventions aimed at increasing people’s level of distress tolerance are emphasized in the management of elevated blood pressure.

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High Fructose Intake Contributes to Elevated Diastolic Blood Pressure in Adolescent Girls: Results from The HELENA Study

Nutrients ◽

10.3390/nu13103608 ◽

2021 ◽

Vol 13 (10) ◽

pp. 3608

Author(s):

Laurent Béghin ◽

Inge Huybrechts ◽

Elodie Drumez ◽

Mathilde Kersting ◽

Ryan W Walker ◽

...

Keyword(s):

Blood Pressure ◽

Diastolic Blood Pressure ◽

Adolescent Girls ◽

Elevated Blood Pressure ◽

Dietary Habit ◽

Elevated Blood ◽

Fructose Intake ◽

High Fructose ◽

Natural Foods ◽

Helena Study

Background: The association between high fructose consumption and elevated blood pressure continues to be controversial, especially in adolescence. The aim of this study was to assess the association between fructose consumption and elevated blood pressure in an European adolescent population. Methods: A total of 1733 adolescents (mean ± SD age: 14.7 ± 1.2; percentage of girls: 52.8%) were analysed from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study in eight European countries. Blood pressure was measured using validated devices and methods for measuring systolic blood pressure (SBP) and diastolic blood pressure (DBP). Dietary data were recorded via repeated 24 h recalls (using specifically developed HELENA–DIAT software) and converted into pure fructose (monosaccharide form) and total fructose exposure (pure fructose + fructose from sucrose) intake using a specific fructose composition database. Food categories were separated at posteriori in natural vs. were non-natural foods. Elevated BP was defined according to the 90th percentile cut-off values and was compared according to tertiles of fructose intake using univariable and multivariable mixed logistic regression models taking into account confounding factors: centre, sex, age and z-score–BMI, MVPA (Moderate to Vigorous Physical Activity) duration, tobacco consumption, salt intake and energy intake. Results: Pure fructose from non-natural foods was only associated with elevated DBP (DBP above the 10th percentile in the highest consuming girls (OR = 2.27 (1.17–4.40); p = 0.015) after adjustment for cofounding factors. Conclusions: Consuming high quantities of non-natural foods was associated with elevated DBP in adolescent girls, which was in part due to high fructose levels in these foods categories. The consumption of natural foods containing fructose, such as whole fruits, does not impact blood pressure and should continue to remain a healthy dietary habit.

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2017 ACC/AHA blood pressure classification and incident peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study

European Journal of Preventive Cardiology ◽

10.1177/2047487319865378 ◽

2019 ◽

Vol 27 (1) ◽

pp. 51-59 ◽

Cited By ~ 1

Author(s):

Yifei Lu ◽

Shoshana H Ballew ◽

Hirofumi Tanaka ◽

Moyses Szklo ◽

Gerardo Heiss ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Diastolic Blood Pressure ◽

Peripheral Artery Disease ◽

Cox Regression ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Peripheral Artery ◽

Artery Disease ◽

Stage 1

Aims The aim of this study was to evaluate the associations of blood pressure categorization based on the 2017 American College of Cardiology and American Heart Association guideline with the risk of peripheral artery disease (PAD). Methods Among 13,113 middle-aged participants, we investigated the associations of 2017 blood pressure categories (systolic <120 and diastolic <80 mmHg (normal if no anti-hypertensive medications; reference), 120–129 and <80 (elevated), 130–139 and/or 80–89 (stage 1 hypertension), and ≥140 and/or ≥90 (stage 2 hypertension)) with incident PAD (hospitalizations with a diagnosis or leg revascularization) using Cox regression models. Analyses were separately conducted in individuals with and without anti-hypertensive medications. Results During a median follow-up of 25.4 years, 466 incident PAD occurred (271 cases in 9858 participants without anti-hypertensive medications). In participants without anti-hypertensive medications, we observed significant hazard ratios of PAD in elevated blood pressure (1.80 (1.28–2.51)) and stage 2 hypertension (2.40 (1.72–3.34)), but not in stage 1 hypertension. Analyzing systolic and diastolic blood pressure separately, higher systolic blood pressure categories showed significant associations with incident PAD in a graded fashion whereas, for diastolic blood pressure, only ≥90 mmHg did. Generally similar patterns were seen among participants on anti-hypertensive medication, while they had higher risk of PAD than those without at each blood pressure category. Conclusions Systolic blood pressure, including the category of 130–139 mmHg, showed stronger associations with incident PAD than did diastolic blood pressure. Consequently, elevated blood pressure conferred similar or even greater risk of PAD than stage 1 hypertension, with implications on how to interpret new blood pressure categories in terms of leg vascular health.

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Plasma Dopamine β-Hydroxylase and Noradrenaline Amounts in Essential Hypertension

Clinical Science ◽

10.1042/cs0440617 ◽

1973 ◽

Vol 44 (6) ◽

pp. 617-620 ◽

Cited By ~ 71

Author(s):

L. B. Geffen ◽

R. A. Rush ◽

W. J. Louis ◽

A. E. Doyle

Keyword(s):

Blood Pressure ◽

Nervous System ◽

Essential Hypertension ◽

Sympathetic Nervous System ◽

Diastolic Blood Pressure ◽

Plasma Catecholamines ◽

Plasma Noradrenaline ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Sympathetic Nervous

1. Plasma dopamine β-hydroxylase (DβH) amounts were measured by radioimmunoassay in twenty-eight patients, twenty of whom had essential hypertension. There was a positive correlation between resting diastolic blood pressure and plasma DβH concentration. 2. Plasma DβH amounts also correlated significantly with those of plasma noradrenaline (NA) in individual patients. 3. These findings provide further support for the conclusions drawn from studies of plasma catecholamines that the sympathetic nervous system contributes toward the maintenance of the elevated blood pressure in essential hypertension.

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Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation

International Journal of Molecular Sciences ◽

10.3390/ijms20174261 ◽

2019 ◽

Vol 20 (17) ◽

pp. 4261 ◽

Cited By ~ 2

Author(s):

Johannes Wild ◽

Rebecca Schüler ◽

Tanja Knopp ◽

Michael Molitor ◽

Sabine Kossmann ◽

...

Keyword(s):

Blood Pressure ◽

Mouse Model ◽

Skin Disease ◽

Vascular Dysfunction ◽

Vascular Inflammation ◽

Skin Inflammation ◽

Severe Psoriasis ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

The Impact

Background: Psoriasis is hallmarked by vascular dysfunction, arterial hypertension, and an increased risk for cardiovascular diseases. We have shown recently that skin-driven interleukin (IL)-17A expression promotes psoriasis-like disease in mice, and this is associated with vascular inflammation, vascular dysfunction, and hypertension. As an intensive risk-factor reduction is recommended for psoriasis patients, we aimed to elucidate the impact of the angiotensin II receptor type 1 (AT1) antagonist telmisartan in a mouse model of severe psoriasis-like skin disease. Methods and Results: Elevated blood pressure measured by tail-cuff plethysmography in mice with keratinocyte-specific IL-17A overexpression (K14-IL-17Aind/+ mice) was significantly reduced in response to telmisartan. Importantly, vascular dysfunction, as assessed by isometric tension studies of isolated aortic rings, vascular inflammation measured by flow cytometry analysis of CD45+CD11b+ immune cells, as well as the increased peripheral oxidative stress levels assessed by L-012-enhanced chemiluminescence were not attenuated by telmisartan treatment of K14-IL-17Aind/+ mice, nor was the persisting skin inflammation. Conclusion: We provide first evidence for an effective antihypertensive treatment in experimental psoriasis by AT1 blockade, but without any impact on vascular inflammation and dysfunction in our mouse model of severe psoriasis-like skin disease. This suggests that vascular function and inflammation in psoriasis might not be attenuated as long as skin inflammation persists.

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Optimal Blood Pressure Keeps Our Brains Younger

Frontiers in Aging Neuroscience ◽

10.3389/fnagi.2021.694982 ◽

2021 ◽

Vol 13 ◽

Author(s):

Nicolas Cherbuin ◽

Erin I. Walsh ◽

Marnie Shaw ◽

Eileen Luders ◽

Kaarin J. Anstey ◽

...

Keyword(s):

Blood Pressure ◽

Risk Factor ◽

Diastolic Blood Pressure ◽

Premature Death ◽

Progressive Increase ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Brain Health ◽

Optimal Blood Pressure ◽

Blood Pressure Range

Background: Elevated blood pressure (BP) is a major health risk factor and the leading global cause of premature death. Hypertension is also a risk factor for cognitive decline and dementia. However, when elevated blood pressure starts impacting cerebral health is less clear. We addressed this gap by estimating how a validated measure of brain health relates to changes in BP over a period of 12 years.Methods: Middle-age (44–46 years at baseline, n = 335, 52% female) and older-age (60–64 years, n = 351, 46% female) cognitively intact individuals underwent up to four brain scans. Brain health was assessed using a machine learning approach to produce an estimate of “observed” age (BrainAGE), which can be contrasted with chronological age. Longitudinal associations between blood pressures and BrainAGE were assessed with linear mixed-effects models.Results: A progressive increase in BP was observed over the follow up (MAP = 0.8 mmHg/year, SD = 0.92; SBP = 1.41 mmHg/year, SD = 1.49; DBP = 0.61 mmHg/year, SD = 0.78). In fully adjusted models, every additional 10 mmHg increase in blood pressure (above 90 for mean, 114 for systolic, and 74 for diastolic blood pressure) was associated with a higher BrainAGE by 65.7 days for mean, and 51.1 days for systolic/diastolic blood pressure. These effects occurred across the blood pressure range and were not exclusively driven by hypertension.Conclusion: Increasing blood pressure is associated with poorer brain health. Compared to a person becoming hypertensive, somebody with an ideal BP is predicted to have a brain that appears more than 6 months younger at midlife.

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The impact of elevated blood pressure upon 10-year mortality among Japanese men in Hawaii: The Honolulu heart program

Journal of Chronic Diseases ◽

10.1016/0021-9681(83)90145-5 ◽

1983 ◽

Vol 36 (8) ◽

pp. 569-579 ◽

Cited By ~ 29

Author(s):

Katsuhiko Yano ◽

Daniel Mcgee ◽

Dwayne M. Reed

Keyword(s):

Blood Pressure ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Japanese Men ◽

The Impact

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Effects of a 4 week touch rugby and self-paced interval running intervention on health markers in active young men

Sport Sciences for Health ◽

10.1007/s11332-020-00636-4 ◽

2020 ◽

Vol 16 (4) ◽

pp. 635-643

Author(s):

Nick Dobbin ◽

Daniel Bloyce ◽

Stephen Fȏn Hughes ◽

Craig Twist

Keyword(s):

Blood Pressure ◽

Body Composition ◽

Diastolic Blood Pressure ◽

Sport Activity ◽

Team Sports ◽

Young Men ◽

Fat Free Mass ◽

Post Intervention ◽

Percentage Body Fat ◽

Inflammatory Status

Abstract Background Modified team sport activity has been proposed as effective exercise modality for promoting markers of health that are comparable or greater than continuous forms of activity. However, research using modified team sports is currently limited to sedentary populations using 2–3 sessions across a minimum of 8 weeks. Aim To investigate the effects of a 4-week touch rugby and self-paced interval running intervention on a range of health markers in active men. Methods Sixteen participants (age 26.4 ± 6.4 years) were matched for age, demographic and physical activity before completing a single touch rugby (n = 8) or running (n = 8) session per week for 4 weeks. Measures of systolic and diastolic blood pressure, resting heart rate (RHR), body composition and biochemical status were recorded pre- and post-intervention. Results ANCOVA analysis revealed between-group differences for impedance (P = 0.027), fat mass (P = 0.008), percentage body fat (P = 0.008) and fat-free mass (P = 0.002), with greater changes after touch rugby. Systolic blood pressure decreased for both groups with greater reductions observed after touch rugby (P = 0.002). No between-group difference was observed for RHR, interleukin-6 or C-reactive protein (P > 0.05). Contrasting internal, external and perceptual loads were observed. Conclusion The results of this study suggest that a single session of touch rugby over a 4-week period elicited greater improvements in body composition and SBP than self-paced running, with both being equally beneficial for improving RHR, diastolic blood pressure and inflammatory status in active young men.

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The Impact of Metabolic Syndrome on the Incidence of Atrial Fibrillation: A Nationwide Longitudinal Cohort Study in South Korea

Journal of Clinical Medicine ◽

10.3390/jcm8081095 ◽

2019 ◽

Vol 8 (8) ◽

pp. 1095 ◽

Cited By ~ 2

Author(s):

Kwon ◽

Kim ◽

...

Keyword(s):

Atrial Fibrillation ◽

Blood Pressure ◽

Metabolic Syndrome ◽

Abdominal Obesity ◽

National Health ◽

Fasting Glucose ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Increased Risk ◽

The Impact

Aims: To evaluate the impact of metabolic syndrome (MetS) status on the incidence of atrial fibrillation (AF) in Koreans. Methods and results: Data obtained from the Korean National Health Insurance Service from 2009 to 2016 were analyzed. In total, 7,830,602 men and women (between 30 and 69 years of age) without baseline AF who underwent a national health examination between January 2009 and December 2009 were enrolled. Patients were evaluated to determine the impact of MetS status on their risk of developing AF until December 2016. Using the National Cholesterol Education Program Adult Treatment Panel III criteria, patients were placed into one of three groups depending on MetS component numbers: 0 (normal), 1–2 (Pre-MetS) or 3–5 (MetS). During a mean follow-up of 7.3 years, 20,708 subjects (0.26%) were diagnosed with AF. After multivariable adjustment, the risk of AF was significantly and positively correlated with MetS status (hazard ratios (HR) 1.391, 95% confidence interval (CI) 1.322–1.464 in Pre-MetS and HR 1.722, 95% CI 1.621–1.829 in MetS). When subgroup analyses were conducted according to MetS components, abdominal obesity (HR 1.316, p < 0.001), elevated blood pressure (HR 1.451, p < 0.001), and elevated fasting glucose (HR 1.163, p < 0.001) were associated with an increased risk of AF. Conclusion: MetS and pre-MetS are significantly associated with an increased risk of AF in Korean adults. Of the MetS components, abdominal obesity, elevated blood pressure, and elevated fasting glucose are potent risk factors for the risk of AF in this population.

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